Search results for " PHOSPHATE"

showing 10 items of 293 documents

Erythrocytäre Anionenkonzentrationen bei renaler Insuffizienz

1966

In chronic renal insufficiency, concentrations of chloride and inorganic phosphate in human red blood cells are elevated. There is no correlation between serum non-protein nitrogen and the anionic concentrations of red blood cells. Positive correlations exist between corresponding cellular and extracellular anionic concentrations.

Pharmacologymedicine.medical_specialtyChemistryCell BiologyChlorideCellular and Molecular NeuroscienceEndocrinologyInorganic phosphateBiochemistryInternal medicinemedicineExtracellularMolecular MedicineChronic renal insufficiencyMolecular Biologymedicine.drugExperientia
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Control of cellular phosphatidylinositol 4,5-bisphosphate levels by adhesion signals and Rho GTPases in NIH 3T3 fibroblasts

2000

The involvement of small GTPases of the Rho family in the control of phosphoinositide metabolism by adhesion signals was examined in NIH 3T3 fibroblasts. Abrogation of adhesion signals by detachment of cells from their substratum resulted in a time-dependent decrease in the cellular level of PtdIns(4,5)P2 by approximately 50%. This effect could be mimicked by treatment of adherent cells with Clostridium difficile toxin B and toxin B-1470, which inhibit specific subsets of Rho and Ras GTPases. Detachment of cells that had been pretreated with the clostridial toxins did not cause a further reduction in PtdIns(4,5)P2 levels, suggesting that the target GTPases are integrated into the control of…

Phosphatidylinositol 45-Diphosphaterac1 GTP-Binding Proteinrho GTP-Binding ProteinsBacterial ToxinsCellClostridium difficile toxin BRAC1GTPasePhospholipaseBiologyTransfectionBiochemistryMicechemistry.chemical_compoundPhosphoinositide Phospholipase CBacterial ProteinsCell AdhesionmedicineAnimalsPhosphorylationInositol phosphatechemistry.chemical_classificationPhospholipase CCytotoxinsPhosphoric Diester Hydrolases3T3 CellsMolecular biologyRecombinant ProteinsCell biologyKineticsPhosphotransferases (Alcohol Group Acceptor)medicine.anatomical_structurechemistryPhosphatidylinositol 45-bisphosphateType C PhospholipasesCalciumSignal TransductionEuropean Journal of Biochemistry
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Regulation of NADPH oxidase-mediated superoxide production by acetylation and deacetylation

2021

Oral treatment of apolipoprotein E-knockout (ApoE-KO) mice with the putative sirtuin 1 (SIRT1) activator resveratrol led to a reduction of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activity in the heart. In contrast, the SIRT1 inhibitor EX527 enhanced the superoxide production in isolated human polymorphonuclear granulocytes. In human monocytic THP-1 cells, phorbol ester-stimulated superoxide production was enhanced by inhibitors of histone deacetylases (HDACs; including quisinostat, trichostatin A (TSA), PCI34051, and tubastatin A) and decreased by inhibitors of histone acetyltransferases [such as garcinol, curcumin, and histone acetyltransferase (HAT) Inhibitor II]. Thes…

Physiologyresveratrolsirtuin 1histone acetyltransferaseSirtuinechemistry.chemical_compoundHistone deacetylasesSirtuin 1Physiology (medical)NADPH-OxidasemedicineQP1-981ddc:610Original ResearchacetylationAcetyltransferasenNADPH oxidasebiologyNADPH oxidaseSirtuin 1SuperoxideAcetylationHistone acetyltransferaseTrichostatin AchemistryBiochemistryHistone acetyltransferasesAcetylationResveratrolNADPH oxidaseshistone deacetylasebiology.proteinHistone deacetylaseDDC 610 / Medicine & healthNicotinamide adenine dinucleotide phosphateRac1medicine.drug
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Mannose phosphate isomerase isoenzymes in Plutella xylostella support common genetic bases of resistance to Bacillus thuringiensis toxins in Llpidopt…

2001

ABSTRACT A strong correlation between two mannose phosphate isomerase (MPI) isoenzymes and resistance to Cry1A toxins from Bacillus thuringiensis has been found in a Plutella xylostella population. MPI linkage to Cry1A resistance had previously been reported for a Heliothis virescens population. The fact that the two populations share similar biochemical, genetic, and cross-resistance profiles of resistance suggests the occurrence of homologous resistance loci in both species.

PopulationBacterial ToxinsBacillus thuringiensisDrug ResistanceIsomeraseApplied Microbiology and BiotechnologyMicrobiologyHemolysin ProteinsBacterial ProteinsBacillus thuringiensisInvertebrate MicrobiologyAnimalseducationPest Control BiologicalGeneticseducation.field_of_studyMannose-6-Phosphate IsomeraseEcologyHeliothis virescensbiologyBacillus thuringiensis ToxinsMannose phosphate isomeraseParasporal bodyfungiPlutellaMannose-6-Phosphate Isomerasebiology.organism_classificationEndotoxinsIsoenzymesLepidopteraElectrophoresis Polyacrylamide GelFood ScienceBiotechnologyApplied and environmental microbiology
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Activation of alpha-1A adrenoceptors mobilizes calcium from the intracellular stores in myocytes from rat portal vein.

1994

International audience; Intracellular free Ca++ concentration ([Ca++]i) was monitored using the fluorescence from the dye fura-2-acetoxymethylester in single myocytes from rat portal vein. In the presence of oxodipine (a L-type Ca++ channel inhibitor), norepinephrine (10 microM) evoked transient increases in [Ca++]i which were related to release of Ca++ from intracellular stores. The alpha-1 adrenoceptors mediating intracellular Ca++ release and inositol phosphate accumulation were identified by using subtype-selective agonists and antagonists. Pretreatment with chloroethylclonidine had little effect on the norepinephrine-induced increase in [Ca++]i and inositol phosphate accumulation. In c…

Portal VeinInositol Phosphates[SDV]Life Sciences [q-bio]Molecular Sequence Data[SDV.BC]Life Sciences [q-bio]/Cellular Biology[SDV.BC.BC]Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC]In Vitro TechniquesAntibodiesMuscle Smooth VascularRats[SDV] Life Sciences [q-bio]NorepinephrineChloride ChannelsReceptors Adrenergic alpha-1[SDV.BC.BC] Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC]AnimalsCalciumAmino Acid SequenceRats Wistar[SDV.BC] Life Sciences [q-bio]/Cellular BiologyAdrenergic alpha-AntagonistsCells CulturedSignal Transduction
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Modelling biological and chemically induced precipitation of calcium phosphate in enhanced biological phosphorus removal systems

2011

The biologically induced precipitation processes can be important in wastewater treatment, in particular treating raw wastewater with high calcium concentration combined with Enhanced Biological Phosphorus Removal. Currently, there is little information and experience in modelling jointly biological and chemical processes. This paper presents a calcium phosphate precipitation model and its inclusion in the Activated Sludge Model No 2d (ASM2d). The proposed precipitation model considers that aqueous phase reactions quickly achieve the chemical equilibrium and that aqueous-solid change is kinetically governed. The model was calibrated using data from four experiments in a Sequencing Batch Rea…

Precipitation (chemical)Waste component removalCalcium PhosphatesKinematicsPrecipitation (chemistry)Sequencing batch reactorWastewater treatmentPrecipitationActivated sludge modelWastewaterChemicals removal (water treatment)Precipitation processchemistry.chemical_compoundMathematical modelCalcium ionAqueous solutionChemical PrecipitationAmorphous calcium phosphateChemical equilibriumsEnvironmental RemediationWaste Management and DisposalEnvironmental Restoration and RemediationCalcium concentrationPriority journalWater Science and TechnologyWaste water managementMathematical modellingChemistryEcological ModelingPhosphorusPollutionRaw wastewatersSequencing batch reactorAmorphous calcium phosphateBiodegradation EnvironmentalEnhanced biological phosphorus removalPollutant removalCalibrationCrystallizationEnvironmental EngineeringInorganic chemistryAqueous phase reactionschemistry.chemical_elementArticleHydroxyapatitePhosphatesNumerical modelSolidChemical engineeringPhysicochemical propertyComputer SimulationCalcium phosphate precipitationBiological water treatmentTECNOLOGIA DEL MEDIO AMBIENTECivil and Structural EngineeringActivated sludge modelActivated sludge processBatch reactorsPrecipitation (chemistry)PhosphorusPrecipitation modelPhosphateChemical processKineticsActivated sludgeCalcium phosphateModels ChemicalActivated sludgePotassiumEnhanced biological phosphorus removalCalciumExperimentsSequencing batch reactorsCalcium phosphate dibasicHydrogenWater Research
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Sulfonation of Triphenylphosphines and Separation of Sulfonated Triphenylphosphines by Crystallization and Solvent Extraction

2007

Abstract The effect of sulfonation conditions on the formation of sulfonated triphenylphosphines and their separation from the post‐reaction mixture, containing concentrated sulphuric acid, was studied. The solvent extraction was found to be a suitable technique to separate sulfonated triphenylphosphines from concentrated sulphuric acid, and the purity and yield was higher than obtained by crystallization from various solvents. Tributyl phosphate was a suitable extractant. Sodium salts of sulfonated triphenylphosphines could then be recovered as precipitates by treating the organic phase with the sodium hydroxide solution and separation by crystallization. The solvent extraction simplified …

Process Chemistry and TechnologyGeneral Chemical EngineeringExtraction (chemistry)Inorganic chemistryFiltration and SeparationGeneral ChemistrySeparation processlaw.inventionchemistry.chemical_compoundchemistrylawSodium hydroxidePhase (matter)Yield (chemistry)Tributyl phosphateCrystallizationTriphenylphosphineSeparation Science and Technology
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NEUROPHYSIOLOGICAL AND NEUROCHEMICAL STUDIES WITH THE ISONICOTINOYLHYDRAZONE OF PYRIDOXAL 5-PHOSPHATE.

1964

Pyridoxal 5-PhosphateBrain chemistryCarboxy-LyasesBiochemistryCellular and Molecular Neurosciencechemistry.chemical_compoundNeurochemicalMesencephalonSeizuresCerebellumPonsIsoniazidPyridoxal phosphateTransaminasesBrain ChemistryPharmacologyMedulla OblongataGallamine TriethiodideChemistryAminobutyratesResearchBrainFrontal LobeElectrophysiologyBiochemistryPyridoxal PhosphateCatsJournal of neurochemistry
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Stabilization of the rhombohedral phase in LiZr2(PO4)3 by thermal quenching

1993

Abstract Two LiZr2(PO4)3 samples, which show rhombohedral and monoclinic symmetries, have been studied by powder XRD and MAS-NMR (31P and 7Li) techniques. In the monoclinic sample phosphorus occupies three crystallographic sites and lithium is preferentially placed in M2 environment. When the samples are subjected to successive heating-quenching treatments, the rhombohedral phase is not appreciably modified while the monoclinic phase is transformed into the rhombohedral one. In the quenched samples only one site for phosphorus has been detected and occupancy of lithium in the more symmetric M1 site is favoured. After the thermal treatments, when the samples are stored at room temperature fo…

QuenchingMagic angleIsotopes of lithiumchemistry.chemical_elementGeneral ChemistryCondensed Matter Physicschemistry.chemical_compoundCrystallographychemistryZirconium phosphatePhase (matter)General Materials ScienceLithiumPhosphorus-31 NMR spectroscopyMonoclinic crystal systemSolid State Ionics
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α1-Adrenoceptors in the rat cerebral cortex: New insights into the characterization of α1L- and α1D-adrenoceptors

2010

36 p., figuras y tablas, bibliografía

Rat cerebral cortexAdrenergic receptorG proteinInositol PhosphatesBiologyAlpha1-adrenoceptor subtypesBinding CompetitiveCytosolReceptors Adrenergic alpha-1medicineAnimalsRNA MessengerRats WistarBinding siteInositol phosphate[3H]prazosin binding studiesCellular localizationCerebral CortexPharmacologychemistry.chemical_classificationReverse Transcriptase Polymerase Chain ReactionCell MembraneRatsCell biologyCytosolmedicine.anatomical_structureGene Expression RegulationBiochemistrychemistryAlpha1L-adrenoceptorsCerebral cortexG-proteinsFemaleGuanosine TriphosphateIntracellularAlpha1D-intracellular localizationEuropean Journal of Pharmacology
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