Search results for " PORC"

A New Prosthetic Implant for Inguinal Hernia Repair: Its Features in a Porcine Experimental Model

2011

Even after more than 100 years of inguinal hernia repair, the rate of complications and recurrence remains unacceptably high. In the last decades, few effective advances in surgical technique and materials have been made. The authors see them as minor adjustments in the shape and materials of the prosthetic implants. Still, the underlying genesis of inguinal hernia remains undefined. Based upon this, it seems the surgical repair of inguinal protrusions cannot be based upon the pathogenesis because the etiology to date has not been addressed. Most hernia repairs are performed with some degree of point fixation (sutures/tacks) to stop the mesh from migrating and creating high recurrence rates…

Phosphonic Acid Analogs of Fluorophenylalanines as Inhibitors of Human and Porcine Aminopeptidases N: Validation of the Importance of the Substitutio…

2020

International audience; A library of phosphonic acid analogs of phenylalanine substituted with fluorine, chlorine and trifluoromethyl moieties on the aromatic ring was synthesized and evaluated for inhibitory activity against human (hAPN) and porcine (pAPN) aminopeptidases. Fluorogenic screening indicated that these analogs are micromolar or submicromolar inhibitors, both enzymes being more active against hAPN. In order to better understand the mode of the action of the most active compounds, molecular modeling was used. It confirmed that aminophosphonic portion of the enzyme is bound nearly identically in the case of all the studied compounds, whereas the difference in activity results fro…

Synthesis and Inhibitory Studies of Phosphonic Acid Analogues of Homophenylalanine and Phenylalanine towards Alanyl Aminopeptidases.

2020

A library of novel phosphonic acid analogues of homophenylalanine and phenylalanine, containing fluorine and bromine atoms in the phenyl ring, have been synthesized. Their inhibitory properties against two important alanine aminopeptidases, of human (hAPN, CD13) and porcine (pAPN) origin, were evaluated. Enzymatic studies and comparison with literature data indicated the higher inhibitory potential of the homophenylalanine over phenylalanine derivatives towards both enzymes. Their inhibition constants were in the submicromolar range for hAPN and the micromolar range for pAPN, with 1-amino-3-(3-fluorophenyl) propylphosphonic acid (compound 15c) being one of the best low-molecular inhibitors …

Fracture Resistance of New Metal-Free Materials Used for CAD-CAM Fabrication of Partial Posterior Restorations

2020

Background and Objectives: To evaluate in vitro the fracture resistance and fracture type of computer-aided design and computer-aided manufacturing (CAD-CAM) materials. Materials and Methods: Discs were fabricated (10 &times

Kernel intensity for space-time point processes with application to seismological problems

2010

Dealing with data coming from a space-time inhomogeneous process, there is often the need of semi-parametric estimates of the conditional intensity function; isotropic or anisotropic multivariate kernel estimates can be used, with windows sizes h. The properties of the intensities estimated with this choice of h are not always good for specific fields of application; we could try to choose h in order to have good predictive properties of the estimated intensity function. Since a direct ML approach cannot be followed, we propose an estimation procedure, computationally intensive, based on the subsequent increments of likelihood obtained adding an observation at time. The first results obtain…

Clinical outcomes of veneered zirconia anterior partial fixed dental prostheses: A 12-year prospective clinical trial

2019

Abstract Statement of problem Anterior veneered zirconia partial fixed dental prostheses (FDPs) have substituted for metal-ceramic to improve esthetics and biocompatibility. However, the material is susceptible to aging or hydrothermal degradation and to chipping of the feldspathic veneer. Whether these susceptibilities limit the clinical performance of anterior veneered zirconia FPDs is unclear. Purpose The purpose of this prospective clinical study was to analyze the mechanical and biologic behavior of zirconia partial FDPs in the anterior region over a 12-year follow-up period. Material and methods Twenty-seven 3- to 6-unit FDPs fabricated from zirconia veneered with feldspathic porcelai…

Review of group A rotavirus strains reported in swine and cattle

2013

Group A rotavirus (RVA) infections cause severe economic losses in intensively reared livestock animals, particularly in herds of swine and cattle. RVA strains are antigenically heterogeneous, and are classified in multiple G and P types defined by the two outer capsid proteins, VP7 and VP4, respectively. This study summarizes published literature on the genetic and antigenic diversity of porcine and bovine RVA strains published over the last 3 decades. The single most prevalent genotype combination among porcine RVA strains was G5P[7], whereas the predominant genotype combination among bovine RVA strains was G6P[5], although spatiotemporal differences in RVA strain distribution were observ…

Food partitioning between Serranus scriba and Scorpaena porcus (Perciformes) on the infralittoral ground of the South Tyrrhenian Sea.

1993

Food preferences of Scorpaena porcus and Serranus scriba were investigated from the stomach contents of fish caught with trammel nets in the Gulf of Palermo (Tyrrhenian Sea). Decapoda Natantia and Decapoda Brachyura were the main preferred prey in the diet of S. porcus whereas Decapoda Natantia, Decapoda Galatheidae and Pisces were the preferred prey for S. scriba. These results and the values of the index of overlapping alimentary requirements suggested competition for food resources between the two species. A more precise investigation, at species level, of the food remains of the most abundant taxon (Crustacea Decapoda) made it possible to demonstrate that the trophic niche overlap betwe…

Transbuccal delivery of l-dopa methyl ester: ex vivo permeation studies

2012

Recensione a Porcelio de’ Pandoni, De sestertio et talento, ediz. critica e trad. ital. a cura di N. Rozza, Napoli, Loffredo, 2022

2023

Review of the critical edition of «De sestertio et talento» by the Neapolitan humanist Porcelio de' Pandoni, edited by Nicoletta Rozza and Andrew Burnett and published in 2022 in Naples by the publisher Loffredo.