Search results for " PREDICTION"

Refining Prognosis in Chemoembolization for Hepatocellular Carcinoma: Immunonutrition and Liver Function

2021

A combination of albumin-bilirubin (ALBI) grading and the Prognostic Nutritional Index (PNI) was identified recently as a highly predictive tool for patients with hepatocellular carcinoma (HCC) undergoing tumor ablation. The present study evaluated this combination in patients undergoing transarterial chemoembolization (TACE). Between 2010 and 2020, 280 treatment-naïve patients were retrospectively identified. The influence of ALBI grade, PNI and the novel ALBI-PNI on the median overall survival (OS) was assessed. In the next step, the prognostic ability of the combined approach was compared to established scoring systems. Both ALBI grade 2−3 and a low PNI were highly predictive for median …

Dynamics and Predictability of a Heavy Dry-Season Precipitation Event over West Africa—Sensitivity Experiments with a Global Model

2009

Abstract In January 2002 the Cape Verde region in tropical West Africa was hit by an exceptionally heavy precipitation event. Rain rates of up to 116 mm (48 h)−1 caused harmful impacts on the local population. The rainfall was triggered by a series of two upper-level disturbances penetrating from the extratropics to the West African coast. This study investigates the dynamics and predictability of this event on the basis of simulations with the global model Global Model Europe (GME) of the German Weather Service [i.e., Deutscher Wetterdienst (DWD)] initialized by the European Centre for Medium-Range Weather Forecasts (ECMWF) analysis data. Free forecasts satisfactorily reproduce the upper-l…

Mating-induced differential peptidomics of neuropeptides and protein hormones in Agrotis ipsilon moths

2018

International audience; In many insects, mating induces drastic changes in male and female responses to sex pheromones or host-plant odors. In the male moth Agrotis ipsilon, mating induces a transient inhibition of behavioral and neuronal responses to the female sex pheromone. As neuropeptides and peptide hormones regulate most behavioral processes, we hypothesize that they could be involved in this mating-dependent olfactory plasticity. Here we used next-generation RNA sequencing and a combination of liquid chromatography, matrix assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry, and direct tissue profiling to analyze the transcriptome and peptidome of diffe…

ChemInform Abstract: New Reactions of Amino-Functionalized 3-Vinyl-1H-indoles and Tetrahydropyridin-4-yl Analogues with Dienophiles.

2010

Reactions of 3-[2-(morpholin-4-yl)vinyl]-1H-indole (1), the 1,2-dihydro-9H-carbazole 2, as well as the 3-(tetrahydropyridin-4-yl)-1H-indoles 3a and 3b with some carbo- and heterodienophiles are described. The scope and limitations of the synthetic utility of these amino- (or homoamino)-functionalized 3-vinyl-1H-indoles are reported and some MO calculations for the qualitative prediction of their reactivities are presented. The reactions gave rise to substitution products, redox products, Diels-Alder adducts, ene adducts, and Michael-type adducts (Schemes 2 and 3).

RIP-Chip analysis supports different roles for AGO2 and GW182 proteins in recruiting and processing microRNA targets.

2019

Background MicroRNAs (miRNAs) are small non-coding RNA molecules mediating the translational repression and degradation of target mRNAs in the cell. Mature miRNAs are used as a template by the RNA-induced silencing complex (RISC) to recognize the complementary mRNAs to be regulated. To discern further RISC functions, we analyzed the activities of two RISC proteins, AGO2 and GW182, in the MCF-7 human breast cancer cell line. Methods We performed three RIP-Chip experiments using either anti-AGO2 or anti-GW182 antibodies and compiled a data set made up of the miRNA and mRNA expression profiles of three samples for each experiment. Specifically, we analyzed the input sample, the immunoprecipita…

Toll-quality digital secraphone

2002

This paper describes the design and performance of a secraphone that, when plugged between any conventional telephone set and the public telephone network, protects the speech information travelling through the PSTN. The device has a transparent operating mode that does not alter the signal and a secure mode, accessed upon request of any of the speakers, that encrypts the speech with digital techniques, assuring privacy against unwanted listeners. At the transmission branch, voice is sampled, coded with a CELP scheme at 9600 bps (with a slow mode at 7200 bps), encrypted with a proprietary algorithm and interfaced to the line with a V.32 modem chip set. The keys for encryption are establishe…

Contextual neural-network based spectrum prediction for cognitive radio

2015

Cognitive radio is the technique of effective electromagnetic spectrum usage important for future wireless communication including 5G networks. Neural networks are nature-inspired computational models used to solve cognitive radio prediction problems. This paper presents the use of contextual Sigma-if neural network in prediction of channel states for cognitive radio. Our results indicate that Sigma-if neural network confirms better predictions than Multilayer Perceptron (MLP) network and decreases sensing time for the benefit of the increase of the effectiveness of e-m spectrum usage.

A Spline Collocation Scheme for the Spherical Shallow Water Equations

1999

CRISPR sequences are sometimes erroneously translated and can contaminate public databases with spurious proteins containing spaced repeats

2020

© The Author(s) 2020.

Measurement, Prediction, and Control of Individual Heart Rate Responses to Exercise-Basics and Options for Wearable Devices.

2018

The use of wearable devices or "wearables" in the physical activity domain has been increasing in the last years. These devices are used as training tools providing the user with detailed information about individual physiological responses and feedback to the physical training process. Advantages in sensor technology, miniaturization, energy consumption and processing power increased the usability of these wearables. Furthermore, available sensor technologies must be reliable, valid, and usable. Considering the variety of the existing sensors not all of them are suitable to be integrated in wearables. The application and development of wearables has to consider the characteristics of the p…