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Precursors of bipolar disorders: A systematic literature review of prospective studies

2015

Objective To evaluate the presence of affective signs and symptoms as precursors of bipolar disorder in prospective studies, including assessment of their prevalence, duration, and predictive value. Data sources We followed PRISMA guidelines to search PubMed, CINAHL, PsycINFO, EMBASE, SCOPUS, and ISI Web of Science databases to May 31, 2013, using the terms bipolar disorder AND (antecedent* OR predict* OR prodrom* OR prospect*) AND (diagnosis OR development). Hand searching of identified reports led to additional relevant references. Study selection We included only English-language articles containing (1) prospective, longitudinal studies with at least 2 structured clinical assessments (in…

medicine.medical_specialtyBipolar DisorderSettore MED/25 - PSCHIATRIANot Otherwise Specifiedbipolar disorder; humans; prodromal symptoms; psychiatry and mental Health; arts and humanities (miscellaneous); medicine (all)MEDLINEProdromal SymptomsPsycINFOmedicine.diseasearts and humanities (miscellaneous)Psychiatry and Mental healthSystematic reviewmental disordersmedicineHumansBipolar disorderMedical diagnosismedicine (all)PsychologyProspective cohort studyPsychiatryDepression (differential diagnoses)Clinical psychology
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