Search results for " Persistence"

showing 7 items of 57 documents

Absence of the lactase-persistence-associated allele in early Neolithic Europeans.

2007

Lactase persistence (LP), the dominant Mendelian trait conferring the ability to digest the milk sugar lactose in adults, has risen to high frequency in central and northern Europeans in the last 20,000 years. This trait is likely to have conferred a selective advantage in individuals who consume appreciable amounts of unfermented milk. Some have argued for the “culture-historical hypothesis,” whereby LP alleles were rare until the advent of dairying early in the Neolithic but then rose rapidly in frequency under natural selection. Others favor the “reverse cause hypothesis,” whereby dairying was adopted in populations with preadaptive high LP allele frequencies. Analysis based on the cons…

medicine.medical_treatmentPopulationLactoseBiologyDNA MitochondrialPolymorphism Single NucleotideBone and BonesWhite PeopleNOLactose IntolerancemedicineHumansAlleleeducationSelectionAllele frequencyAllelesHistory AncientLactaseGeneticseducation.field_of_studyMultidisciplinaryNatural selectionAncient DNAHaplotypeLactaseEmigration and ImmigrationBiological SciencesAncient DNA Dairying SelectionEuropeDairyingLactase persistenceAncient DNAGenetics PopulationTandem Repeat SequencesToothProceedings of the National Academy of Sciences of the United States of America
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Pharmacokinetics of new oral anticoagulants: implications for use in routine care

2018

Introduction: Since 2008, new oral anticoagulants (NOACs) have been approved for the prevention of venous thromboembolism (VTE) in patients receiving hip or knee replacement surgery, prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation (NVAF), treatment of deep vein thrombosis (DVT), and pulmonary embolism (PE). Premarketing randomized clinical trials (RCTs) of NOACs demonstrated their non-inferiority in terms of efficacy vs. warfarin (traditional oral anticoagulant–TOA), with lower risk of serious adverse drug reactions, especially cerebral hemorrhages. In clinical practice, pharmacokinetic aspects of NOACs have to be carefully taken into account to …

medicine.medical_treatmentnew oral anticoagulantsAdministration OralKnee replacement030204 cardiovascular system & hematologyToxicologyAdherence Bleeding Interactions New oral anticoagulants Over- and under-dosage Persistence Pharmacokinetics Real World Evidence0302 clinical medicineAtrial Fibrillationover- and underdosage030212 general & internal medicinepharmacokineticStrokeRoutine careRandomized Controlled Trials as Topicnew oral anticoagulantAtrial fibrillationpersistenceVenous ThromboembolismGeneral MedicinePulmonary embolismStrokepharmacokineticsHumanmusculoskeletal diseasesmedicine.medical_specialtyinteractionHemorrhageMedication Adherence03 medical and health sciencesPharmacokineticsmedicineHumansReal World EvidenceIn patientOver- and under-dosagecardiovascular diseasesreal-world evidenceIntensive care medicineAgedPharmacologybusiness.industryAnticoagulantAnticoagulantsinteractionsbleedingmedicine.diseaseAdherencePulmonary EmbolismbusinessVenous thromboembolismExpert Opinion on Drug Metabolism & Toxicology
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Prolonged stigma and flower lifespan in females of the gynodioecious plant Geranium sylvaticum

2017

In gynodioecious plants females need a reproductive advantage over hermaphrodites to be maintained in the same population. Generally, three main proximate causes for a female advantage are considered: inbreeding avoidance, different resource allocation patterns, and differences in ecological interactions. A mechanism potentially causing a female advantage that is rarely discussed is a difference in floral longevity between the genders. Females may have a longer stigma lifespan than hermaphrodites, which can affect pollination. Stigma and flower lifespan are rarely documented in gynodioecious species, although it is a common observation in dioecious species that female plants flower longer t…

pollen limitationfemale advantageflower persistencefungifood and beveragesgynodioecypölytysinbreeding avoidance
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Poverty Persistence Among Youth: A Comparative Analysis

2008

poverty persistence youth ECHP
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New insight on the role of the oral mucosa in aroma release

2017

saliva[SDV.AEN] Life Sciences [q-bio]/Food and Nutrition[SPI.GPROC] Engineering Sciences [physics]/Chemical and Process Engineering[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process Engineeringaroma persistence[SDV.AEN]Life Sciences [q-bio]/Food and Nutritionmucosa
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Role of mucosa and mucosal pellicle in aroma persistence

2016

International audience

salivacell culture[SDV.AEN] Life Sciences [q-bio]/Food and Nutritionmucosal pellicle[SPI.GPROC] Engineering Sciences [physics]/Chemical and Process Engineering[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process Engineeringaroma persistence[SDV.AEN]Life Sciences [q-bio]/Food and NutritionComputingMilieux_MISCELLANEOUS
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Patterns of Children’s Relationships With Parents and Teachers in Grade 1 : Links to Task Persistence and Performance

2022

Our study aimed to investigate the patterns of children’s relationships with their parents and teachers, the development of these relationships during Grade 1, and respective links to children’s learning (in task persistence and performance). Parents of 350 children answered questionnaires about the quality of their relationships with their children; 25 teachers answered questions about children’s task persistence at school and the quality of their relationships with their students; 350 children completed literacy and math performance tests; and six testers evaluated children’s task persistence when completing those tests. All measures were administered twice: at the start and end of Grade …

vanhempi-lapsisuhdeopintomenestysteacher-student relationshipGrade 1educationalakoululaisetparent-child relationshipbehavioral disciplines and activitiesopettaja-oppilassuhdeperformancetask persistence
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