Search results for " Phase"

showing 10 items of 1862 documents

Vitamin D kinetics in the acute phase of critical illness: A prospective observational study.

2017

Abstract Purpose The objective of this study was to assess the vitamin D kinetics in critically ill patients by performing periodic serum vitamin D measurements in short time intervals in the initial phase of a critical illness. Materials and methods We performed vitamin D serum measurements: at admission and then in 12-hour time intervals. The minimum number of vitamin D measurements was 4, and the maximum was 8 per patient. Results A total of 363 patients were evaluated for participation, and 20 met the inclusion criteria. All patients had an initial serum vitamin D level between 10.6 and 39 ng/mL. Nineteen patients had vitamin D levels between 10 and 30 ng/mL, which means that they had v…

AdultMalemedicine.medical_specialtyCritical IllnessCritical Care and Intensive Care MedicineGastroenterologyvitamin D deficiency03 medical and health sciencesPlasma0302 clinical medicineIntensive careInternal medicineSeverity of illnessmedicineVitamin D and neurologyHumans030212 general & internal medicineProspective StudiesVitamin DProspective cohort studyAgedbusiness.industryDiagnostic Tests Routine030208 emergency & critical care medicineMiddle Agedmedicine.diseaseVitamin D DeficiencySurgeryHospitalizationInitial phaseCritical illnessAcute DiseaseObservational studyFemalebusinessJournal of critical care
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Biomonitoring of Multiple Mycotoxins in Urine by GC–MS/MS: A Pilot Study on Patients with Esophageal Cancer in Golestan Province, Northeastern Iran

2021

A pilot study to investigate the occurrence of 10 mycotoxins (deoxynivalenol, DON

AdultMalemedicine.medical_specialtyEsophageal NeoplasmsLiquid Phase MicroextractionHealth Toxicology and Mutagenesislcsh:MedicinePilot ProjectsUrineIranToxicologymedicine.disease_cause01 natural sciencesGastroenterologyDiacetoxyscirpenolGas Chromatography-Mass SpectrometryArticlechemistry.chemical_compoundYoung Adult0404 agricultural biotechnologyInternal medicinemycotoxinsmedicineHumansZearalanoneesophageal cancerMycotoxinZearalenoneAgedAged 80 and overCreatininebusiness.industryToxin010401 analytical chemistrylcsh:RGC–MS/MSurine biomarkers04 agricultural and veterinary sciencesMiddle Aged040401 food science0104 chemical scienceschemistryCase-Control StudiesBody BurdenFemaleGas chromatography–mass spectrometrybusinessBiological MonitoringToxins
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Arterially enhancing liver lesions: significance of sustained enhancement on hepatic venous and delayed phase with magnetic resonance imaging.

2007

Benign hepatic vascular neoplasms and vascular pseudolesions are commonly encountered in magnetic resonance (MR) imaging. Most of these benign lesions demonstrate not only arterial-phase hyperintensity, but also persistent enhancement on venous and delayed imaging, unlike most malignant hepatic masses. These features, along with other MR findings and morphological characteristics, may allow for more confident diagnosis and distinction from hepatic malignancy. The objective of our study was to illustrate the MR imaging findings of hepatic lesions that demonstrate both early arterial and sustained enhancement on hepatic venous and delayed phase.

AdultMalemedicine.medical_specialtyHepatic VeinsHepatic ArteryVascular NeoplasmmedicineDelayed imagingHumansRadiology Nuclear Medicine and imagingmedicine.diagnostic_testbusiness.industryLiver DiseasesLiver NeoplasmsMagnetic resonance imagingDelayed phaseMiddle AgedMr imagingMagnetic Resonance ImagingHepatic malignancyHyperintensityRadiographic Image EnhancementRadiographic Image EnhancementFemaleRadiologyNuclear medicinebusinessJournal of computer assisted tomography
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Effects of plantar flexor muscle fatigue induced by electromyostimulation on postural coordination

2007

International audience; The aim of the present study was to investigate the influence of a modification of an intrinsic capacity (plantar flexor strength) on the implementation of in-phase and anti-phase mode of coordination. Analysis of hip and ankle relative phases during fore-aft tracking task was done before and after an electromyostimulation fatigue protocol on the soleus muscles. Results showed participants used exclusively in-phase and anti-phase modes of coordination, with a sudden switch from one to the other with target frequency increase. Regarding tracking tasks, fatigue induces a decrease of performance for lower frequencies, and a significant decrease of switch frequency (−0.0…

AdultMalemedicine.medical_specialtyMovementPosturePlantar flexion03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationIsometric ContractionHumansMedicine[PHYS.MECA.BIOM]Physics [physics]/Mechanics [physics]/Biomechanics [physics.med-ph]Muscle SkeletalRelative phases[ PHYS.MECA.BIOM ] Physics [physics]/Mechanics [physics]/Biomechanics [physics.med-ph]LegHipMuscle fatiguebusiness.industryGeneral Neuroscience[SPI.MECA.BIOM]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Biomechanics [physics.med-ph]030229 sport sciencesFlexor musclesAdaptation PhysiologicalElectric StimulationConstraintmedicine.anatomical_structureTorqueMuscle FatiguePhysical therapyAnkle[ SPI.MECA.BIOM ] Engineering Sciences [physics]/Mechanics [physics.med-ph]/Biomechanics [physics.med-ph]Anklebusiness030217 neurology & neurosurgeryMuscle ContractionNeuroscience Letters
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"Baseline physical functioning status of metastatic colorectal cancer patients predicts the overall survival but not the activity of a front-line oxa…

2010

BACKGROUND: No differences in response rate (RR), progression-free survival (PFS), overall survival (OS) and quality of life (QoL) were seen in patients randomly treated with biweekly oxaliplatin plus either fluorouracil/folinic acid or capecitabine. METHODS: We investigated the independent effect of baseline clinical characteristics and physical functioning (PF) domain on RR, PFS, and OS in 310 patients who completed the EORTC QLQ-C30 questionnaire. Multivariate analyses stratified by treatment were performed. An exploratory analysis was done by grouping patients with a PF score superior or equal to the highest quartile (n = 111), included between the highest and the lowest quartiles (n = …

AdultMalemedicine.medical_specialtyMultivariate analysisColorectal cancerSettore MED/06 - Oncologia MedicaKaplan-Meier EstimateGastroenterologyDisease-Free SurvivalCapecitabineTreatment Outcome; Prognosis; Aged 80 and over; Male; Retrospective Studies; Randomized Controlled Trials as Topic; Middle Aged; Kaplan-Meier Estimate; Colorectal Neoplasms; Female; Disease-Free Survival; Humans; Quality of Life; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials Phase III as Topic; Aged; Adult; Health Status Indicators; Multicenter Studies as TopicFolinic acidQuality of lifeInternal medicineAntineoplastic Combined Chemotherapy Protocols80 and overmedicineOverall survivalHealth Status IndicatorsHumansMulticenter Studies as TopicClinical TrialsRadiology Nuclear Medicine and imagingneoplasmsmetastatic colorectal canceroxaliplatin physical functioning statusAgedRandomized Controlled Trials as TopicRetrospective StudiesAged 80 and overbusiness.industryHematologyGeneral MedicineMiddle AgedPrognosismedicine.diseaseSurgeryOxaliplatinPhase III as TopicTreatment OutcomeClinical Trials Phase III as TopicOncologyQuartileQuality of LifeFemaleColorectal Neoplasmsbusinessmedicine.drug
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Meibomian glands structure in daily disposable soft contact lens wearers: a one‐year follow‐up study

2020

Purpose To assess the impact of daily disposable soft contact lenses on meibomian gland morphology over a period of 12 months. Methods Forty-one subjects (33 experienced and 8 neophytes) were fitted with either silicone-hydrogel or hydrogel daily contact lenses. The study protocol included four visits: baseline, day-2 for contact lens fit and follow-up measurements, as well as after 6 and 12 months of lens wear. Non-contact infrared meibography images were acquired with Keratograph 5M topographer (www.oculus.de) and analysed with an automated method, which objectively estimates the area of gland atrophy, gland length and width, number of glands and gland irregularity. Protocol at follow-up …

AdultMalemedicine.medical_specialtyOne year follow upMeibomian glandlaw.inventionYoung Adult03 medical and health sciences0302 clinical medicineAtrophylawOphthalmologyHumansMedicineOcular Surface Disease IndexProspective StudiesVision Ocularbusiness.industryOsmolar ConcentrationMeibomian GlandsContact Lenses Hydrophilicmedicine.diseaseeye diseasesSensory SystemsLens (optics)Contact lensOphthalmologymedicine.anatomical_structurePatient SatisfactionTears030221 ophthalmology & optometryFemaleDaily disposablesense organsbusinessEarly phase030217 neurology & neurosurgeryFollow-Up StudiesOptometryOphthalmic and Physiological Optics
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A randomised clinical trial to evaluate the acceptability and efficacy of an early phase, online, guided augmentation of outpatient care for adults w…

2019

AbstractBackgroundOutpatient interventions for adult anorexia nervosa typically have a modest impact on weight and eating disorder symptomatology. This study examined whether adding a brief online intervention focused on enhancing motivation to change and the development of a recovery identity (RecoveryMANTRA) would improve outcomes in adults with anorexia nervosa.MethodsParticipants with anorexia nervosa (n= 187) were recruited from 22 eating disorder outpatient services throughout the UK. They were randomised to receiving RecoveryMANTRA in addition to treatment as usual (TAU) (n= 99; experimental group) or TAU only (n= 88; control group). Outcomes were measured at end-of-intervention (6 w…

AdultMalemedicine.medical_specialtySocial adjustmentAdolescentPsychological interventionAnorexia nervosa; augmentation; early symptom change; feasibility; guidance; motivation; online; recovery; self-help; trialAnxietyBody Mass IndexYoung AdultrecoveryAmbulatory caremotivationSettore M-PSI/08 - Psicologia ClinicaaugmentationmedicineHumansAnorexia nervosa augmentation early symptom change feasibility guidance motivation online recovery self-help trialearly symptom changeself-helpApplied PsychologyonlineInternetbusiness.industryAnorexia nervosatrialClinical trialSelf CarePsychiatry and Mental healthAnorexia nervosa (differential diagnoses)Physical therapyAnxietyFemalemedicine.symptomEarly phasebusinessBody mass indexguidancefeasibility
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Prognostic Factors Determining Long-Term Survival in Well-Differentiated Thyroid Cancer: An Analysis of Four Hundred Eighty-Four Patients Undergoing …

2003

Identification of the prognostic factors relevant for long-term survival in differentiated thyroid cancer in a homogenously treated patient cohort in order to allow a better initial risk stratification.Four hundred eighty-four (358 females/126 males) patients with differentiated thyroid cancer (330 papillary [68.2%]; 154 follicular [31.8%]) were included. Inclusion criteria consisted of treatment with a uniform therapy scheme and continuous aftercare in the same institution. Initial diagnosis was between 1975-1995 (age at diagnosis, 14-84 years, median, 49.7). Tumor stage: pT1, n = 92; pT2, 211; pT3, 58; pT4, 123. Low-risk:or=pT3 NX M0, 331; high-risk pT4 and/or M1, 153. After thyroidectomy…

AdultMalemedicine.medical_specialtyTime FactorsEndocrinology Diabetes and Metabolismmedicine.medical_treatmentEndocrinologyRecurrenceCause of DeathInternal medicineAdenocarcinoma FollicularFollicular phaseLong term survivalmedicineHumansSurvivorsThyroid NeoplasmsThyroid cancerAgedNeoplasm StagingRetrospective StudiesCause of deathAged 80 and overbusiness.industryWell-Differentiated Thyroid CancerThyroidectomyRetrospective cohort studyMiddle Agedmedicine.diseaseSurgeryAdenocarcinoma PapillaryCohortFemalebusinessFollow-Up StudiesThyroid
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Differences in contractile behaviour between the soleus and medial gastrocnemius muscles during human walking

2012

The functional roles of individual lower limb muscles during human walking may differ depending on walking speed or duration. In this study, 11 volunteers walked on a treadmill for 60 min at speeds corresponding to both optimal and 20% above optimal energetic cost of transport whilst oxygen consumption and medial gastrocnemius (MG) and soleus fascicle lengths were measured. Although energetic cost of transport was ∼12% higher at the faster speed, it remained constant over 60 min at both speeds, suggesting that humans can walk for prolonged periods at a range of speeds without compromising energetic efficiency. The fascicles of both muscles exhibited rather ‘isometric’ behaviour during the e…

AdultMalemedicine.medical_specialtyTime FactorsPhysiologyMovementMedial gastrocnemiusEnergetic costWalkingAquatic ScienceYoung AdultOxygen ConsumptionPhysical medicine and rehabilitationFunctional importancemedicineHumansTreadmillMuscle SkeletalGaitMolecular BiologyEcology Evolution Behavior and SystematicsStance phaseChemistryAnatomyFascicleRespiratory quotientPreferred walking speedInsect ScienceExercise TestFemaleAnimal Science and Zoologyhuman activitiesMuscle ContractionJournal of Experimental Biology
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GnRH agonist administration at the time of implantation does not improve pregnancy outcome in intrauterine insemination cycles: a randomized controll…

2009

Objective To assess whether GnRH agonist administration in the luteal phase improves pregnancy outcome in intrauterine insemination (IUI) cycles. Design Single-center, randomized, single-blind, placebo-controlled trial. Setting University-affiliated infertility clinic, between February 2005 and December 2007. Patient(s) Three hundred forty-four women undergoing IUI owing to mild to moderate male factor or donor sperm indication. Intervention(s) Random administration to either a single subcutaneous injection of 0.1 mg triptorelin (group A; n = 172) 8 days after hCG administration, or solvent only (group B; n=172) at the same time. Main Outcome Measure(s) Pregnancy rate was the primary outcom…

AdultMalemedicine.medical_specialtyTime FactorsPregnancy Ratemedicine.medical_treatmentLuteal phaseDrug Administration Schedulelaw.inventionMiscarriageGonadotropin-Releasing HormonePlacebosRandomized controlled triallawPregnancyMedicineHumansSingle-Blind MethodEmbryo ImplantationInsemination ArtificialGynecologyPregnancyTriptorelin Pamoatebusiness.industryObstetricsArtificial inseminationUterusPregnancy OutcomeObstetrics and GynecologyFertility Agents Femalemedicine.diseaseTriptorelinPregnancy rateReproductive MedicineGestationFemalebusinessAlgorithmsmedicine.drugFertility and sterility
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