Search results for " Physicochemical"

showing 10 items of 22 documents

Physicochemical Characterization, Antioxidant Activity, and Phenolic Compounds of Hawthorn (Crataegus spp.) Fruits Species for Potential Use in Food …

2020

Hawthorn belongs to the Crataegus genus of the Rosaceae family and is an important medicinal plant. Due to its beneficial effects on the cardiovascular system and its antioxidant and antimicrobial activity hawthorn has recently become quite a popular herbal medicine in phytotherapy and food applications. In this study, physicochemical characterization (color parameters, pH, titratable acidity, total soluble solids, soluble carbohydrate, total carotenoid, total phenols, and flavonoid contents), antioxidant activity (by ferric-reducing antioxidant power, FRAP assay), and quantification of some individual phenolic compounds of fruits of 15 samples of different hawthorn species (Crataegus spp.)…

Health (social science)030309 nutrition & dieteticsCrataegus spp.Flavonoidphysicochemical characteristicsHyperosidephenolic compoundsPlant Sciencelcsh:Chemical technologyHealth Professions (miscellaneous)MicrobiologyArticleCrataegus03 medical and health scienceschemistry.chemical_compound0404 agricultural biotechnologyChlorogenic acidlcsh:TP1-1185Food sciencePhenolsGallic acidchemistry.chemical_classification0303 health sciencesbioactive compoundsbiology<i>Crataegus</i> spp.; bioactive compounds; physicochemical characteristics; phenolic compounds; flavonoids<i>Crataegus</i> spp.04 agricultural and veterinary sciencesbiology.organism_classification040401 food sciencechemistryPhytochemicalflavonoidsQuercetinFood ScienceFoods
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Systematic study of the physicochemical properties of a homologous series of aminobisphosphonates

2012

ABSTRACT: Aminobisphosphonates, e.g., alendronate and neridronate, are a well known class of molecules used as drugs for various bone diseases. Although these molecules have been available for decades, a detailed understanding of their most important physicochemical properties under comparable conditions is lacking. In this study, ten aminobisphosphonates, H2N(CH2)nC(OH)[P(O)(OH)2]2, in which n = 2-5, 7-11 and 15 have been synthesized. Their aqueous solubility as a function of temperature and pH, pKa-values, thermal stability, IR absorptions, and NMR spectral data for both liquid (1H, 13C, 31P-NMR) and solid state (13C, 15N and 31P-CPMAS NMR) were determined. Peer reviewed

Magnetic Resonance Spectroscopy116 Chemical sciencesSolid-statePharmaceutical Sciencephysicochemical properties010402 general chemistry01 natural sciencesArticleAnalytical Chemistrylcsh:QD241-441Homologous serieschemistry.chemical_compoundlcsh:Organic chemistryComputational chemistrybisphosphonates; aqueous solubility; pKa; physicochemical propertiesaqueous solubilityDrug DiscoveryAqueous solubilityMoleculeOrganic chemistrypKaThermal stabilityPhysical and Theoretical ChemistrySolubilitySpectral datata116bisphosphonatesAlendronateDiphosphonates010405 organic chemistryChemistryOrganic ChemistryTemperaturebisphosphonates aqueous solubility pKa physicochemical propertiesWaterNuclear magnetic resonance spectroscopyHydrogen-Ion Concentration0104 chemical sciences3. Good healthSolubilityChemistry (miscellaneous)Molecular Medicine
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Chemometric and chemoinformatic analyses of anabolic and androgenic activities of testosterone and dihydrotestosterone analogues

2008

Predictive quantitative structure-activity relationship (QSAR) models of anabolic and androgenic activities for the testosterone and dihydrotestosterone steroid analogues were obtained by means of multiple linear regression using quantum and physicochemical molecular descriptors (MD) as well as a genetic algorithm for the selection of the best subset of variables. Quantitative models found for describing the anabolic (androgenic) activity are significant from a statistical point of view: R2 of 0.84 (0.72 and 0.70). A leave-one-out cross-validation procedure revealed that the regression models had a fairly good predictability [q2 of 0.80 (0.60 and 0.59)]. In addition, other QSAR models were …

MaleQuantitative structure–activity relationshipAnabolismStereochemistrymedicine.medical_treatmentClinical BiochemistryAnabolic and androgenic activitiesQSAR modelQuantitative Structure-Activity RelationshipPharmaceutical ScienceBiochemistrySteroidAnabolic AgentsMolecular descriptorDrug DiscoveryLinear regressionmedicineCluster AnalysisHumansComputer SimulationTestosteroneMolecular BiologyChemistryOrganic ChemistryDihydrotestosteroneModels ChemicalGenetic algorithmDihydrotestosteroneAndrogensQuantum and physicochemical molecular descriptorMolecular MedicineTestosterone and dihydrotestosterone steroid analoguesAlgorithmsAnabolic steroidApplicability domainmedicine.drugBioorganic and Medicinal Chemistry 16: 6448-6459 (2008)
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Passivation-Induced Physicochemical Alterations of the Native Surface Oxide Film on 316L Austenitic Stainless Steel

2019

Time of Flight Secondary Ion Mass Spectroscopy, X-Ray Photoelectron Spectroscopy, in situ Photo-Current Spectroscopy and electrochemical analysis were combined to characterize the physicochemical alterations induced by electrochemical passivation of the surface oxide film providing corrosion resistance to 316L stainless steel. The as-prepared surface is covered by a ~2 nm thick, mixed (Cr(III)-Fe(III)) and bi-layered hydroxylated oxide. The inner layer is highly enriched in Cr(III) and the outer layer less so. Molybdenum is concentrated, mostly as Mo(VI), in the outer layer. Nickel is only present at trace level. These inner and outer layers have band gap values of 3.0 and 2.6-2.7 eV, respe…

Materials sciencePassivation020209 energyOxidechemistry.chemical_elementFOS: Physical sciences02 engineering and technologyApplied Physics (physics.app-ph)Surface Analysisengineering.materialPhysical ChemistryMetallic MaterialsCorrosionBarrier layerchemistry.chemical_compoundPassive Film0202 electrical engineering electronic engineering information engineeringMaterials ChemistryElectrochemistry[CHIM]Chemical SciencesAustenitic stainless steelPassivation Physicochemical Characterization Native Surface Oxide 316L Austenitic Stainless SteelCondensed Matter - Materials ScienceRenewable Energy Sustainability and the EnvironmentMaterials Science (cond-mat.mtrl-sci)Physics - Applied Physics[CHIM.MATE]Chemical Sciences/Material chemistryStainless SteelCondensed Matter PhysicsSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsCorrosionNickelSettore ING-IND/23 - Chimica Fisica ApplicatachemistryChemical engineering13. Climate actionMolybdenum[PHYS.COND.CM-MS]Physics [physics]/Condensed Matter [cond-mat]/Materials Science [cond-mat.mtrl-sci]engineeringLayer (electronics)Journal of The Electrochemical Society
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Effect of refrigerated storage on microbiological, chemical and sensory characteristics of a ewes’ raw milk stretched cheese

2017

This study aimed to describe the effects of refrigerated storage up to 180 days on microbiological, chemical, physical, and sensory characteristics of a PDO ewes’ raw milk stretched cheese. To this aim, a total of 224 cheeses were manufactured in four consecutive production weeks, and series of 32 of them were examined before packaging and after 15, 30, 60, 90, 120, and 180 d of storage at 4 ± 2 °C in the dark, respectively. Lactic acid bacteria cocci displayed the highest levels (7.8 Log CFU*g−1) during early storage and decreased progressively over time (7.4 Log CFU*g−1), while the opposite trend was observed for lactic acid bacteria rods (from 6.5 to 7.3 Log CFU*g−1). TMC and enterocci s…

Microbiology (medical)Settore AGR/19 - Zootecnica SpecialePolymers and PlasticsFresh cheese; Physicochemical properties; Sensory analysis; Shelf-life; Storage; Food Science; Biomaterials; Safety Risk Reliability and Quality; Polymers and Plastics; Microbiology (medical)Sensory analysiStoragePhysicochemical propertieBiomaterialschemistry.chemical_compound0404 agricultural biotechnologyBrowningSettore AGR/18 - Nutrizione E Alimentazione AnimaleFood scienceSolubilitySafety Risk Reliability and QualityPolymers and PlasticbiologyShelf-life0402 animal and dairy science04 agricultural and veterinary sciencesRaw milkbiology.organism_classification040401 food science040201 dairy & animal scienceBiomaterialLactic acidchemistryOdorFatty acid compositionFresh cheeseBacteriaFood ScienceSettore AGR/16 - Microbiologia Agraria
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The effects of the traditional producing system on physicochemical, microbial and sensory properties of Caciocavallo Palermitano cheese

2015

Caciocavallo Palermitano (CP) is a traditional cheese made with raw milk from cows of Sicilian local breeds fed pasture-based diets in extensive farms (EXT), processed by an artisanal technology (ART) based on wooden tools and the action of native microflora. CP is obtained also in intensive farms (INT) where milk from cows of specialized breeds fed dry diets is transformed by advanced procedures (ADV) using a stainless steel equipment and lactic acid starter cultures. This research was planned to investigate the changes in cheese properties due to production system and ripening., Milk was collected 3 times from an EXT and an INT farm and processed in ART and ADV conditions. The 12 produced…

Settore AGR/19 - Zootecnica SpecialeTraditional production system Caciocavallo Palermitano Cheese microbial characteristics physicochemical e sensory propertiesSettore AGR/16 - Microbiologia Agraria
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Influence of Citrus Essential Oils on the Microbiological, Physicochemical and Antioxidant Properties of Primosale Cheese

2022

The aim of this study was to produce a fresh ovine pressed cheese within Pecorino &ldquo;Primosale&rdquo; typology with the addition of citrus essential oils (EOs). For this purpose, ewe&rsquo;s pasteurized milk was added with EOs from the peel of lemons, oranges and tangerines. Seven cheese productions were performed at the pilot plant scale level, including one control production (CP) without the addition of EOs and six experimental productions obtained by the addition of two EO concentrations (100 and 200 &micro;L/L) to milk. The acidification process was obtained by means of the starter cultures Lactococcus lactis CAG4 and PON36. All cheeses showed levels of lactic acid bacteria (LAB) a…

Settore AGR/19 - Zootecnica Specialeovine cheese; citrus essential oils; <i>Lactococcus lactis</i>; physicochemical properties; volatile organic compounds; antioxidant capacityPhysiologySettore AGR/13 - Chimica AgrariaClinical BiochemistryCell BiologyMolecular BiologyBiochemistryantioxidant capacity citrus essential oils Lactococcus lactis ovine cheese physicochemical properties volatile organic compoundsSettore AGR/16 - Microbiologia AgrariaAntioxidants
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Properties of titanium dioxide

2021

"Properties of titanium dioxide" presents a survey of the main physicochemical properties of TiO2 upon which rely all of the applications of this material. Structures and morphologies of titanium dioxide have been taken into account, also in correlation with thermodynamic properties. Bulk and surface defectivity has been described in detail, because of its relevant consequences in terms of catalytic activity. The basic mechanisms of interaction between photons and TiO2 have been discussed on the basis of the optoelectronic features of the semiconductor. Finally, electrical, mechanical, and rheological properties of TiO2 have been presented.

Titanium dioxide Physicochemical properties Photocatalytic activity. Optoelectronic propertieschemistry.chemical_compoundMaterials scienceSemiconductorchemistrybusiness.industryTitanium dioxideNanotechnologyChemical stabilityBiocompatible materialbusiness
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Applying pattern recognition methods plus quantum and physico-chemical molecular descriptors to analyze the anabolic activity of structurally diverse…

2008

The great cost associated with the development of new anabolic-androgenic steroid (AASs) makes necessary the development of computational methods that shorten the drug discovery pipeline. Toward this end, quantum, and physicochemical molecular descriptors, plus linear discriminant analysis (LDA) were used to analyze the anabolic/androgenic activity of structurally diverse steroids and to discover novel AASs, as well as also to give a structural interpretation of their anabolic-androgenic ratio (AAR). The obtained models are able to correctly classify 91.67% (86.27%) of the AASs in the training (test) sets, respectively. The results of predictions on the 10% full-out cross-validation test al…

Virtual screeningQuantitative structure–activity relationshipAnabolismChemical PhenomenaQuantitative Structure-Activity RelationshipComputational biologyLDA-assisted QSAR modelLigandsPattern Recognition AutomatedAnabolic AgentsMolecular descriptorCluster AnalysisComputer SimulationVirtual screeningMolecular StructureChemistryChemistry PhysicalDiscriminant AnalysisReproducibility of ResultsGeneral ChemistryLinear discriminant analysisCombinatorial chemistryAnabolic–androgenic ratioComputational MathematicsPattern recognition (psychology)Quantum and physicochemical molecular descriptorQuantum TheorySteroidsAnabolic–androgenic steroidAlgorithmsJournal of computational chemistry
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Physicochemical, Nutraceutical and Sensory Traits of Six Papaya (Carica papaya L.) Cultivars Grown in Greenhouse Conditions in the Mediterranean Clim…

2020

Six papaya (Carica papaya L.) cultivars, grown in a Mediterranean climate under greenhouse conditions, were screened for physicochemical properties, antioxidant capacity, nutritional and sensory characteristics. The fruits, harvested with more than 50% of yellow surface (between 60% and 77%) were tested for carotenoids content, phenolic content, reducing activity (ABTS) and cellular antioxidant activity (CAA50). The physicochemical traits were measured in terms of the titratable acidity and soluble content whereas proximal composition along with moisture, fats, total sugar, ash, vitamin A, C and E content. Moreover, the sensory profile was analyzed by a semi-trained panel. Although the six …

antiproliferative activityantioxidant activityTitratable acidBiologySensory analysislcsh:Agriculturechemistry.chemical_compound0404 agricultural biotechnologySettore BIO/10 - BiochimicaCultivarSugarCarotenoidCarotenoidchemistry.chemical_classificationABTSfruit qualitycarotenoidsphysicochemicallcsh:Sfood and beverages04 agricultural and veterinary sciencesSweetnessbiology.organism_classification040401 food scienceSettore AGR/03 - Arboricoltura Generale E Coltivazioni ArboreeHorticulturechemistry040103 agronomy & agricultureAntioxidant activity; Antiproliferative activity; Carotenoids; Fruit quality; Physicochemical0401 agriculture forestry and fisheriesCaricaAgronomy and Crop ScienceAgronomy
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