Search results for " Plastic"

showing 10 items of 3463 documents

Immunotherapy With Human Gamma Delta T Cells—Synergistic Potential of Epigenetic Drugs?

2018

Epigenetics has emerged as one of the fastest growing concepts, adding more than 45 new publications every day, spreading through various fields ( 1). Conrad Waddington coined the term “epigenetics” in 1942; however, a multitude of definitions has been endorsed by different researchers. In essence, Waddington’s definition of “epigenetics” and its redefinition by Holiday is at the heart of cellular function. Hence, it is obvious that epigenetic regulation plays a central role also in the specification, differentiation, and functional plasticity of T lymphocytes ( 2). T-cell fate decision in progenitor cells, functional CD4 T-cell plasticity, CD8 T-cell differentiation, but also T-cell memory…

Checkpoint Inhibitorslcsh:Immunologic diseases. Allergy0301 basic medicineDeltaOpinionmedicine.medical_treatmentImmune checkpoint inhibitorsCell PlasticityImmunologyNatural-killer Group 2 Member DBiologyEpigenesis Genetic03 medical and health sciencesCell Plasticitymedicineddc:6AnimalsHumansgamma delta T cellsImmunology and Allergyddc:610EpigeneticsIntraepithelial Lymphocytesprogrammed death 1DNA methylationnatural-killer group 2 member DProgrammed Death 1articlehistone acetylationGamma Delta T CellsImmunotherapy030104 developmental biologyHistone acetylationDNA methylationCancer researchIntraepithelial lymphocyteBromodomain And Extraterminal DomainBromodomain and ExtraTerminal domainImmunotherapyimmunotherapyProgrammed death 1lcsh:RC581-607checkpoint inhibitorsFrontiers in Immunology
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Dynamic Self-Consistent Field Approach for Studying Kinetic Processes in Multiblock Copolymer Melts

2020

The self-consistent field theory is a popular and highly successful theoretical framework for studying equilibrium (co)polymer systems at the mesoscopic level. Dynamic density functionals allow one to use this framework for studying dynamical processes in the diffusive, non-inertial regime. The central quantity in these approaches is the mobility function, which describes the effect of chain connectivity on the nonlocal response of monomers to thermodynamic driving fields. In a recent study [Mantha et al, Macromolecules 53, 3409 (2020)], we have developed a method to systematically construct mobility functions from reference fine-grained simulations. Here we focus on melts of linear chains …

Chemical Physics (physics.chem-ph)Physicsordering kineticsMesoscopic physicsPolymers and PlasticsField (physics)Thermodynamic equilibriumDynamic structure factorFOS: Physical sciencesNon-equilibrium thermodynamicsContext (language use)General ChemistryCondensed Matter - Soft Condensed MatterDynamic densityArticlelcsh:QD241-441lcsh:Organic chemistrydynamic density functional theoryPhysics - Chemical Physicstwo-length scale copolymerssingle chain structure factorSoft Condensed Matter (cond-mat.soft)Density functional theoryStatistical physicsmultiblock copolymersPolymers
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New Lignocellulosic Aristida adscensionis Fibers as Novel Reinforcement for Composite Materials: Extraction, Characterization and Weibull Distributio…

2019

In this research, the Aristida adscensionis fibers (AAFs) were taken out from the plants and its fundamental properties anlayzed for the first time. The AAFs were characterized and compared with other natural fibers by the use of physico-chemical analysis and various characterization techniques such as FT-IR, XRD, NMR, TGA, SEM and AFM. Chemical analysis showed that A. adscensionis fibers have a high cellulose content of 70.78% whereas the contents of lignin and wax are equal to 8.91% and 2.26%, respectively. The FT-IR, XRD and NMR analysis confirmed that AAFs are rich in cellulose content with CI and CS equal to 58.9% and 11.5 nm, respectively. Pycnometer analysis allowed to estimate a den…

Chemical analysiEnvironmental EngineeringMaterials sciencePolymers and PlasticsCharacterizationAristida adscensionisExtraction02 engineering and technologySingle fiber tensile testchemistry.chemical_compound020401 chemical engineeringUltimate tensile strengthMaterials ChemistryLigninFiber0204 chemical engineeringCelluloseComposite materialWeibull distributionWaxbiologyExtraction (chemistry)021001 nanoscience & nanotechnologybiology.organism_classificationSettore ING-IND/22 - Scienza E Tecnologia Dei Materialichemistryvisual_artvisual_art.visual_art_mediumPhysical analysi0210 nano-technologyAristida adscensionis fiber
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Direct identification of 103–107Mo by a rapid chemical separation procedure

1977

Abstract The nuclides 103–107Mo have been identified by means of γ-ray spectroscopy after the separation of molybdenum from fission products of 235U and 239Pu by a rapid chemical procedure. Half-lives of 67.5 ± 1.5 s for 103Mo, 59.4 ± 0.8 s for 104Mo, 36.7 ± 1.0 s for 105Mo, 8.4 ± 0.5 s for 106Mo and 3.5 ± 0.5 s for 107Mo have been determined and the main γ-lines were assigned to the decay of these isotopes. Some evidence for 108Mo with a half-life ≤2 s has also been obtained.

Chemical procedureChemical separationFission productsPolymers and PlasticsIsotopeChemistryMolybdenumMaterials ChemistryAnalytical chemistrychemistry.chemical_elementNuclideSpectroscopyJournal of Inorganic and Nuclear Chemistry
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Neural inflammation alters synaptic plasticity probed by 10 Hz repetitive magnetic stimulation

2020

ABSTRACTSystemic inflammation is associated with alterations in complex brain functions such as learning and memory. However, diagnostic approaches to functionally assess and quantify inflammation-associated alterations in synaptic plasticity are not well-established. In previous work, we demonstrated that bacterial lipopolysaccharide (LPS)-induced systemic inflammation alters the ability of hippocampal neurons to express synaptic plasticity, i.e., the long-term potentiation (LTP) of excitatory neurotransmission. Here, we tested whether synaptic plasticity induced by repetitive magnetic stimulation (rMS), a non-invasive brain stimulation technique used in clinical practice, is affected by L…

ChemistryBrain stimulationSynaptic plasticityExcitatory postsynaptic potentialStimulationTumor necrosis factor alphaLong-term potentiationNeurotransmissionHippocampal formationNeuroscience
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Detecting Cd adaptation footprint in C. riparius with a multi-genomic approach

2021

AbstractEvolutionary processes and acquired tolerance to toxicants are important factors governing how animals respond to chemical exposure. Evidence for increased tolerance to cadmium (Cd), a widely distributed toxic metal in aquatic environments, in Chironomus riparius is conflicting and still questioned if it happens through phenotypic plasticity or genetic adaptation. The present study considered the relevance of directional environmental changes by increasing contaminant concentration in a multigenerational selection experiment. Evaluation of measurable life-cycle traits, transcriptomic responses and quantitative genetics from an evolve and resequencing (E&R) experiment were integr…

Chironomus ripariusTranscriptomeGeneticsPhenotypic plasticityved/biologyved/biology.organism_classification_rank.speciesQuantitative geneticsAdaptationBiologyIncreased toleranceGeneGenetic adaptation
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Pullulan and dextran: uncommon composition dependent Flory-Huggins interaction parameters of their aqueous solutions.

2008

Vapor pressure measurements were performed for aqueous solutions of pullulan ( M w 280 kg/mol) and dextran ( M w 60 and 2100 kg/mol, respectively) at 25, 37.5, and 50 degrees C. The Flory-Huggins interaction parameters obtained from these measurements, plus information on dilute solutions taken from the literature, show that water is a better solvent for pullulan than for dextran. Furthermore, they evince uncommon composition dependencies, including the concurrent appearance of two extrema, a minimum at moderate polymer concentration and a maximum at high polymer concentration. To model these findings, a previously established approach, subdividing the mixing process into two clearly separa…

Chromatography GasPolymers and PlasticsVapor pressureThermodynamicsBioengineeringFlory–Huggins solution theoryBiomaterialschemistry.chemical_compoundMaterials ChemistryPressureSolubilityGlucanschemistry.chemical_classificationAqueous solutionChromatographyWaterPullulanDextransPolymerSolventMolecular WeightDextranchemistryModels ChemicalSolventsThermodynamicsBiomacromolecules
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Interaction of polyelectrolytes with oppositely charged micelles studied by fluorescence and liquid chromatography

2005

It is studied by spectrofluorimetry the association of ionized cationic micelles (cetyltrimethylammonium bromide, CTAB) with oppositely charged polyelectrolyte [sodium poly(styrenesulfonate), PSSNa]. CTAB provokes a change in the fluorescence intensity emitted by PSSNa. The investigated surfactants form micelle-like aggregates before critical micellar concentration (CMC). Two approaches (binding and partition equilibrium) are used to obtain the association constant, KA, number of CTAB molecules in a binding site, N, and apparent partition coefficient, Γ. Analysis of the parameters as a function of polymer concentration and ionic strength μ is performed. The effect of μ shows an enhancement …

ChromatographyAqueous solutionPolymers and PlasticsChemistryOrganic ChemistryGeneral Physics and AstronomyMicellePolyelectrolytePartition coefficientchemistry.chemical_compoundBromideIonic strengthPartition equilibriumCritical micelle concentrationMaterials ChemistryEuropean Polymer Journal
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New insights on the thermal analysis of low moisture composite foods.

2014

Abstract Low moisture baked products were investigated with a view to characterising the effect of both formulation and humidity on their physical stability. At the end of the baking process, the samples were in the amorphous state as a result of starch gelatinization and sugar melting. Their thermal properties were analyzed with differential scanning calorimetry and their glass transitions were studied. The DSC thermograms were thoroughly studied through a Gaussian deconvolution of the first derivative of their heat flow. This approach evidenced a multiple phase behavior with different glass transitions in composite systems. They were associated with either a polymer-rich phase and/or a pl…

ChromatographyMaterials sciencePolymers and PlasticsMoistureCalorimetry Differential ScanningOrganic ChemistryComposite numberFlourCarbohydratesTemperatureHumidityAmorphous solidStarch gelatinizationDifferential scanning calorimetryChemical engineeringPhase (matter)Materials ChemistryThermal analysisGlass transitionFood AnalysisCarbohydrate polymers
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MALDI-TOF characterization of macromonomers

1996

Methacryloyl endfunctionalized oligostyrene macromonomers were characterized by matrix assisted laser desorption ionization/time of flight (MALDI-TOF) spectroscopy and by isocratic and gradient high performance liquid chromatography (HPLC). The molar mass distribution derived by the different techniques coincide for the investigated oligomers. Mixing experiments revealed that the MALDI-TOF peak areas do not necessarily represent the mixing ratio of the components. Combination of gradient HPLC and MALDI-TOF has resolved the chemical composition of the coupling products formed by reaction of the living anion with oxygen.

ChromatographyPolymers and PlasticsChemistryOrganic ChemistryMatrix isolationAnalytical chemistryMass spectrometryMacromonomerHigh-performance liquid chromatographyTime of flightMatrix-assisted laser desorption/ionizationMaterials ChemistryMolar mass distributionSpectroscopyMacromolecular Rapid Communications
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