Search results for " Positron emission tomography"

showing 10 items of 22 documents

18F-Florbetaben PET/CT to Assess Alzheimer's Disease: A new Analysis Method for Regional Amyloid Quantification.

2019

Background and purpose While AD can be definitively confirmed by postmortem histopathologic examination, in vivo imaging may improve the clinician's ability to identify AD at the earliest stage. The aim of the study was to test the performance of amyloid PET using new processing imaging algorithm for more precise diagnosis of AD. Methods Amyloid PET results using a new processing imaging algorithm (MRI-Less and AAL Atlas) were correlated with clinical, cognitive status, CSF analysis, and other imaging. The regional SUVR using the white matter of cerebellum as reference region and scores from clinical and cognitive tests were used to create ROC curves. Leave-one-out cross-validation was carr…

Male18F-florbetabenAmyloidSensitivity and SpecificityAmyloid-PET Imaging030218 nuclear medicine & medical imagingWhite matter03 medical and health sciences0302 clinical medicineAlzheimer DiseasePositron Emission Tomography Computed Tomographymental disordersStilbenesmedicineImage Processing Computer-AssistedDementiaHumansRadiology Nuclear Medicine and imaging18F-florbetaben; Alzheimer's disease; Amyloid-PET Imaging; MR-lessAgedRetrospective StudiesPET-CTAniline CompoundsReceiver operating characteristicbusiness.industry18F-florbetaben Alzheimer's disease Amyloid-PET Imaging MR-less Aged Alzheimer Disease Female Humans Image Processing Computer-Assisted Magnetic Resonance Imaging Male Positron Emission Tomography Computed Tomography Retrospective Studies Sensitivity and Specificity Aniline Compounds StilbenesAlzheimer's diseasemedicine.diseaseMagnetic Resonance Imagingmedicine.anatomical_structureMR-lessFemaleNeurology (clinical)Differential diagnosisNuclear medicinebusiness030217 neurology & neurosurgeryPreclinical imagingFrontotemporal dementiaJournal of neuroimaging : official journal of the American Society of Neuroimaging
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Impact of positron emission tomography on strategy in liver resection for primary and secondary liver tumors.

2003

Outcome of patients with metastatic disease mainly depends on accurate preoperative tumor staging. 18[F]fluorodeoxyglucose positron emission tomography (18F-PET) has been proven to be a valuable diagnostic tool in a number of different tumors but its direct influence on liver surgery has not been thoroughly investigated. Between July 1999 and March 2000, 50 consecutive patients with 174 suspected liver lesions were admitted to the University Hospital Jena. All 50 patients underwent abdominal ultrasound, CT-scan, and 18-FDG positron emission tomography scanning. In 23 patients the diagnostic work-up was completed by MRI scan. Altogether there were a total of 174 histologically proven intrahe…

MaleCancer Researchmedicine.medical_specialtyFluorine RadioisotopesLiver tumorCarcinoma HepatocellularBreast NeoplasmsSensitivity and SpecificityResectionAdenoma Liver CellFluorodeoxyglucose positron emission tomographyFluorodeoxyglucose F18Internal medicinemedicineHumansMri scanNeoplasm StagingHematologymedicine.diagnostic_testbusiness.industryUltrasoundLiver NeoplasmsGeneral Medicinemedicine.diseaseUniversity hospitalOncologyPositron emission tomographyFemaleRadiologyRadiopharmaceuticalsbusinessNuclear medicineColorectal NeoplasmsFollow-Up StudiesTomography Emission-ComputedJournal of cancer research and clinical oncology
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Stereotactic Ablative Radiation Therapy for Lung Oligometastases: Predictive Parameters of Early Response by (18)FDG-PET/CT

2017

Abstract Objectives The objective of this study was to investigate fludeoxyglucose F 18 positron emission tomography/computed tomography ( 18 FDG-PET/CT) parameters as predictive of response after stereotactic ablative radiotherapy (SABR) for lung oligometastases. Methods The inclusion criteria of the current retrospective study were as follows: (1) lung oligometastases treated by SABR, (2) presence of 18 FDG-PET/CT before and after SABR for at least two subsequent evaluations, (3) Karnofsky performance status higher than 80, and (4) life expectancy longer than 6 months. All patients were treated with a biologically equivalent dose of at least 100 Gy with an alpha/beta ratio of 10. The foll…

MaleFludeoxyglucose F-18Lung Neoplasmsmedicine.medical_treatment18FDG-PET/CT; Lung malignancies; Predictive factors; SABR; Adenocarcinoma; Aged; Aged 80 and over; Carcinoma Non-Small-Cell Lung; Carcinoma Squamous Cell; Female; Fluorodeoxyglucose F18; Follow-Up Studies; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Recurrence Local; Neoplasm Staging; Positron Emission Tomography Computed Tomography; Prognosis; Radiopharmaceuticals; Retrospective Studies; Tumor Burden; Radiosurgery; Oncology; Pulmonary and Respiratory MedicineSABR volatility model030218 nuclear medicine & medical imaging0302 clinical medicinePositron Emission Tomography Computed TomographyAblative case80 and overMedicineNon-Small-Cell LungSABRmedicine.diagnostic_test(18)FDG-PET/CTMiddle AgedPrognosisTumor Burdenmedicine.anatomical_structureLocalOncologyPositron emission tomography030220 oncology & carcinogenesisLymphatic MetastasisFemaleRadiologyPredictive factorsPulmonary and Respiratory Medicinemedicine.medical_specialtyLung malignanciesStandardized uptake value18FDG-PET/CTAdenocarcinomaRadiosurgery03 medical and health sciencesFluorodeoxyglucose F18HumansAgedNeoplasm StagingRetrospective StudiesLungbusiness.industryCarcinomaRetrospective cohort studyRadiation therapyNeoplasm RecurrenceSquamous CellRadiopharmaceuticalsbusinessNuclear medicineFollow-Up Studies(18)FDG-PET/CT; Lung malignancies; Predictive factors; SABR
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Dysfunction of attention switching networks in amyotrophic lateral sclerosis

2019

Objective To localise and characterise changes in cognitive networks in Amyotrophic Lateral Sclerosis (ALS) using source analysis of mismatch negativity (MMN) waveforms. Rationale The MMN waveform has an increased average delay in ALS. MMN has been attributed to change detection and involuntary attention switching. This therefore indicates pathological impairment of the neural network components which generate these functions. Source localisation can mitigate the poor spatial resolution of sensor-level EEG analysis by associating the sensor-level signals to the contributing brain sources. The functional activity in each generating source can therefore be individually measured and investigat…

MaleMismatch negativitySource localisationEEG ElectroencephalographyMismatch negativityNetworkElectroencephalographylcsh:RC346-429PET Positron emission tomographyCognition0302 clinical medicineC9orf72AttentionEEGAUROC Area under receiver operating characteristic curveAmyotrophic lateral sclerosisAged 80 and overmedicine.diagnostic_test05 social sciencesCognitive flexibilityBrainRegular ArticleElectroencephalographyCognitionMiddle AgedSTG Superior temporal gyrusNeurologyMTG Mid temporal gyrusDLPFC Dorsolateral prefrontal cortexlcsh:R858-859.7FemaleLCMV Linearly constrained minimum varianceIFG Inferior frontal gyrusAdultCognitive Neurosciencelcsh:Computer applications to medicine. Medical informatics050105 experimental psychologyCWIT Colour-word interference test03 medical and health sciencesfMRI Functional magnetic resonance imagingMEG MagnetoencephalographymedicineMMN Mismatch negativityHumans0501 psychology and cognitive sciencesRadiology Nuclear Medicine and imagingLS Amyotrophic Lateral SclerosisAAL Automated Anatomical Labellinglcsh:Neurology. Diseases of the nervous systemAEP Auditory evoked potentialAgedbusiness.industryAmyotrophic Lateral SclerosisIQR Interquartile rangeNeurophysiologyqEEG Quantitative EEGmedicine.diseaseNeurology (clinical)Nerve NetFunctional magnetic resonance imagingbusinessNeuroscience030217 neurology & neurosurgeryeLORETA Exact low-resolution brain electromagnetic tomographyNeuroImage: Clinical
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A preliminary PET radiomics study of brain metastases using a fully automatic segmentation method

2020

AbstractBackgroundPositron Emission Tomography (PET) is increasingly utilized in radiomics studies for treatment evaluation purposes. Nevertheless, lesion volume identification in PET images is a critical and still challenging step in the process of radiomics, due to the low spatial resolution and high noise level of PET images. Currently, the biological target volume (BTV) is manually contoured by nuclear physicians, with a time expensive and operator-dependent procedure.This study aims to obtain BTVs from cerebral metastases in patients who underwent L-[11C]methionine (11C-MET) PET, using a fully automatic procedure and to use these BTVs to extract radiomics features to stratify between p…

MalePositron emission tomographyComputer scienceLesion volumelcsh:Computer applications to medicine. Medical informaticsBiochemistry030218 nuclear medicine & medical imagingLesion03 medical and health sciences0302 clinical medicineRadiomicsStructural BiologyArtificial IntelligencemedicineHumansSegmentationNeoplasm Metastasislcsh:QH301-705.5Molecular BiologyCancerActive contour modelRadiomicsmedicine.diagnostic_testBrain Neoplasmsbusiness.industryApplied MathematicsResearchCancerPattern recognitionMiddle AgedPrognosismedicine.diseaseComputer Science ApplicationsCancer treatmentBiological target volumelcsh:Biology (General)Positron emission tomographyFeature (computer vision)030220 oncology & carcinogenesisPositron-Emission TomographyFully automaticlcsh:R858-859.7FemaleActive contourArtificial intelligencemedicine.symptomRadiomicActive contour; Biological target volume; Cancer; Positron emission tomography; Radiomics.businessBMC Bioinformatics
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Radiomics analysis of 18F-Choline PET/CT in the prediction of disease outcome in high-risk prostate cancer: an explorative study on machine learning …

2021

Objective: The aim of this study was (1) to investigate the application of texture analysis of choline PET/CT images in prostate cancer (PCa) patients and (2) to propose a machine-learning radiomics model able to select PET features predictive of disease progression in PCa patients with a same high-risk class at restaging. Material and methods: Ninety-four high-risk PCa patients who underwent restaging Cho-PET/CT were analyzed. Follow-up data were recorded for a minimum of 13 months after the PET/CT scan. PET images were imported in LIFEx toolbox to extract 51 features from each lesion. A statistical system based on correlation matrix and point-biserial-correlation coefficient has been impl…

Malemedicine.medical_specialtyMachine learningcomputer.software_genre030218 nuclear medicine & medical imagingCholineCorrelationMachine Learning03 medical and health sciences0302 clinical medicineArtificial IntelligencePositron Emission Tomography Computed TomographymedicineHumansRadiology Nuclear Medicine and imagingCholine; Machine learning; Positron emission tomography computed tomography; Prostate cancer; Radiomics.Prospective StudiesEntropy (energy dispersal)Prospective cohort studySurvival analysisPET-CTbusiness.industryProstatic NeoplasmsGeneral MedicineLinear discriminant analysismedicine.diseasePrimary tumorFeature (computer vision)030220 oncology & carcinogenesisRadiologyArtificial intelligenceNeoplasm Recurrence LocalbusinesscomputerMachine learning Positron emission tomography computed tomography Prostate cancer Radiomics Artificial Intelligence
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Imaging standardisation in metastatic colorectal cancer: a joint EORTC-ESOI-ESGAR expert consensus recommendation

2022

Background: Treatment monitoring in metastatic colorectal cancer (mCRC) relies on imaging to evaluate the tumor burden. Response Evaluation Criteria in Solid Tumors (RECIST) provide a framework on reporting and interpretation of imaging findings yet offer no guidance on a standardized imaging protocol tailored to mCRC patients. Imaging protocol heterogeneity remains a challenge for the reproducibility of conventional imaging endpoints and is an obstacle for research on novel imaging endpoints. Patients and methods: Acknowledging the recently highlighted potential of radiomics and artificial intelligence (AI) tools as decision support for patient care in mCRC, a multidisciplinary, internatio…

PROTOCOLCancer ResearchPositron emission tomographyArtificial intelligenceConsensusBEVACIZUMABMedizinImagingCancer -- ImagingHumansCRITERIAColon (Anatomy) -- Cancer -- TomographyComputed tomographyScience & TechnologyRadiomicsRectal NeoplasmsAbdomen -- Radiography -- Case studiesColon (Anatomy) -- Cancer -- TreatmentReproducibility of ResultsAbdomen -- Radiography -- StandardsOPEN-LABELColorectal cancerArtificial intelligence Standardisation Colorectal cancer Computed tomography Imaging Positron emission tomography RadiomicsOncologyColonic NeoplasmsSURVIVALStandardisationLife Sciences & Biomedicine
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Current Practices in the Management of Pulmonary Ground-Glass Opacities: A Survey of SICT Members

2018

Background Several gray areas and controversies exist concerning the management of pulmonary ground-glass opacities (GGOs), and there is a lack of consensus among clinicians on this topic. One of the main aims of the Italian Society of Thoracic Surgery is to promote education and research, so we decided to perform a survey on this topic to estimate current trends in practice in a large sample of thoracic surgeons. Methods A total of 160 thoracic surgeons responded, namely, completed our questionnaire (response rate, 53%; 160 of 302). The survey was composed of 36 questions divided into six subsections: (1) demographic characteristics of the respondents; (2) terminology and taxonomy; (3) rad…

Pulmonary and Respiratory MedicineMalemedicine.medical_specialtyLung NeoplasmsOutcome AssessmentAttitude of Health PersonnelComputed tomographyPractice Patterns030204 cardiovascular system & hematologyRisk AssessmentLung/diagnostic imaging Lung/pathology Lung Neoplasms/diagnostic imaging*Fluorodeoxyglucose positron emission tomography03 medical and health sciences0302 clinical medicineSettore MED/21 - CHIRURGIA TORACICAMedicalSurveys and QuestionnairesOutcome Assessment Health CaremedicineHumansPractice Patterns Physicians'TomographyLungSocieties MedicalSurgeonsPhysicians'medicine.diagnostic_testbusiness.industryGeneral surgeryConsensus conferenceThoracic SurgeryLarge sampleX-Ray ComputedHealth CareItalyCardiothoracic surgery030220 oncology & carcinogenesisHealth Care SurveysPositron-Emission TomographyCell lung-cancer Invasive adenocarcinoma Wedge resection In-situ Classification Association Tomography Lobectomy Diagnosis HistorySurgeryFemaleLung resectionCardiology and Cardiovascular MedicinebusinessSocietiesTomography X-Ray ComputedAttitude of Health Personnel; Female; Health Care Surveys; Humans; Italy; Lung; Lung Neoplasms; Male; Positron-Emission Tomography; Practice Patterns Physicians'; Risk Assessment; Societies Medical; Surgeons; Thoracic Surgery; Tomography X-Ray Computed; Outcome Assessment Health Care; Surveys and Questionnaires
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Robustness of PET Radiomics Features: Impact of Co-Registration with MRI

2021

Radiomics holds great promise in the field of cancer management. However, the clinical application of radiomics has been hampered by uncertainty about the robustness of the features extracted from the images. Previous studies have reported that radiomics features are sensitive to changes in voxel size resampling and interpolation, image perturbation, or slice thickness. This study aims to observe the variability of positron emission tomography (PET) radiomics features under the impact of co-registration with magnetic resonance imaging (MRI) using the difference percentage coefficient, and the Spearman’s correlation coefficient for three groups of images: (i) original PET, (ii) PET after co-…

TechnologyTomografía de emisión de positronesNeoplasias encefálicasCorrelation coefficientImagen por resonancia magnética:Phenomena and Processes::Mathematical Concepts::Probability::Uncertainty [Medical Subject Headings]QH301-705.5Computer scienceQC1-999:Diseases::Neoplasms::Neoplasms by Site::Nervous System Neoplasms::Central Nervous System Neoplasms::Brain Neoplasms [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Magnetic Resonance Imaging [Medical Subject Headings]Co registrationFluid-attenuated inversion recovery:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Magnetic resonance imagingRadiomicsRobustness (computer science):Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Techniques Radioisotope::Radionuclide Imaging::Tomography Emission-Computed::Positron-Emission Tomography [Medical Subject Headings]Resamplingradiomics feature robustness; imaging quantification; [11C]-methionine positron emission tomography; PET/MRI co-registration Appl.medicineGeneral Materials ScienceBiology (General)QD1-999InstrumentationSettore ING-INF/05 - Sistemi Di Elaborazione Delle InformazioniFluid Flow and Transfer Processesmedicine.diagnostic_testbusiness.industryTPhysicsProcess Chemistry and TechnologyRadiomics feature robustnessGeneral EngineeringPET/MRI co-registrationMagnetic resonance imagingPattern recognitionEngineering (General). Civil engineering (General)Imaging quantificationComputer Science ApplicationsChemistry:Chemicals and Drugs::Amino Acids Peptides and Proteins::Amino Acids::Amino Acids Essential::Methionine [Medical Subject Headings]Positron emission tomography[11C]-methionine positron emission tomography:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis [Medical Subject Headings]Artificial intelligenceTA1-2040businessApplied Sciences
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Role of fluorine 18 fluorodeoxyglucose positron emission tomography/computed tomography in gastrointestinal cancers

2015

AbstractFluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) has become a routine imaging modality for many malignancies and its use is currently increasing. In the present review article, we will summarize the evidence for FDG-PET/CT use in digestive cancers (excluding neuroendocrine tumours), and review the existing recommendations. While PET/CT is nowadays considered to be an important tool in the initial workup of oesophageal and anal cancers, new data are emerging regarding its use in assessing therapeutic efficacy, radiotherapy treatment planning, and detection of recurrence in case of isolated tumour marker elevation. Moreover, PET/CT may help …

medicine.medical_specialtyColorectal cancerColonoscopyDigestive System NeoplasmsMultimodal ImagingPatient Care PlanningFluorodeoxyglucose positron emission tomographyFluorodeoxyglucose F18Pancreatic cancerHumansMedicinePositron Emission Tomography-Computed TomographyFluorine-18-fluorodeoxyglucoseHepatologymedicine.diagnostic_testbusiness.industryOesophageal cancerGastroenterologyPancreatic cancerRadiotherapy treatment planningPrognosismedicine.diseaseColorectal cancerFDG-PET/CTAnal canal cancerReview articleNeuroendocrine TumorsPositron-Emission TomographyPractice Guidelines as TopicRadiologyNeoplasm Recurrence LocalRadiopharmaceuticalsTomography X-Ray ComputedbusinessDigestive and Liver Disease
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