Search results for " Preschool."
showing 10 items of 2092 documents
Validation of the French national health insurance information system as a tool in vaccine safety assessment: Application to febrile convulsions afte…
2013
In the French national health insurance information system (SNIIR-AM), routine records of health claimed reimbursements are linked to hospital admissions for the whole French population. The main focus of this work is the usability of this system for vaccine safety assessment programme. Self-controlled case series analyses were performed using an exhaustive SNIIR-AM extraction of French children aged less than 3 years, to investigate the relationship between MMR immunization and children hospitalizations for febrile convulsions, a well-documented rare adverse event, over 2009-2010. The results suggest a significant increase of febrile convulsions during the 6-11 days period following any MM…
'I had to help my child!': The role of emotions, risk, and trust in use of nasal decongestants in children.
2013
Recent studies suggest that a number of common cold medicines, including nasal decongestants are not suitable for small children. In Latvia nasal decongestants are primarily over-the-counter (OTC) medicines, and patient information leaflets generally permit use of these medicines for small children. The previous studies in Latvia investigating the use of medicines in cases of common cold demonstrated extensive use of decongestants in children less than six years of age, marking a necessity for more profound research. As a result a qualitative study was implemented in 2011 to identify sources of information that offer advice for the use of decongestants in children. The caregivers’ percepti…
Protecting sensitive patient groups from imaging using ionizing radiation: effects during pregnancy, in fetal life and childhood
2019
The frequency of imaging examinations requiring radiation exposure in children (especially CT) is rapidly increasing. This paper reviews the current evidence in radiation protection in pediatric imaging, focusing on the recent knowledge of the biological risk related to low doses exposure. Even if there are no strictly defined limits for patient radiation exposure, it is recommended to try to keep doses as low as reasonably achievable (the ALARA principle). To achieve ALARA, several techniques to reduce the radiation dose in radiation-sensitive patients groups are reviewed. The most recent recommendations that provide guidance regarding imaging of pregnant women are also summarized, and the…
Acute pancreatitis in children and rotavirus infection. Description of a case and minireview
2012
In this article, we describe a case of acute pancreatitis occurred on a 2-year-old boy following rotavirus gastroenteritis. Its characteristics are analyzed and contextualized among those of other 4 cases of pancreatitis associated with rotavirus infection found through a systematic review of the international literature. None of the five children underwent surgery or was referred to an intensive care unit and all the 5 children cured with normalization of pancreatic enzyme within 5-10 days. The pathogenesis of this rare complication remains to be cleared, and its actual incidence may be higher than that reported. Although acute pancreatitis associated with rotavirus gastroenteritis seems t…
Rotavirus infections, vaccines and virus variability
2014
Detection of a porcine-like rotavirus in a child with enteritis in Italy.
2008
ABSTRACT During a 1-year rotavirus surveillance of children hospitalized with acute gastroenteritis in Brescia Hospital, Italy, a chimerical rotavirus strain, G3P[6], was detected, displaying the VP7 and VP4 genes of porcine origin and the NSP4 and VP6 genes of human origin. The reassortant nature of the virus rules out a direct zoonotic event.
Monitoring the rate of hospitalization before rotavirus immunization in Italy utilizing ICD9-CM regional databases
2009
BACKGROUND: Recently, two Rotavirus (RV) vaccines were licensed in Italy, rendering RV illness a vaccine preventable disease. To assess the RV hospitalization rate in Italy, a study focused on the Regional hospital discharge forms (HDD) databases was carried out. RESULTS: Regional HDD databases from Piemonte, Veneto, Friuli-Venezia-Giulia and Marche were analyzed. A total of 434,335 hospitalizations were counted in the study timeframe and 13,234 VE diagnoses (3% of hospitalizations) were collected. A total of 8546 RVE cases (2% of hospitalizations, 64% of all VE) were observed, of which 1.2% were primary diagnoses (PD) and 0.8% secondary diagnosis (SD). The RVE hospitalization peak (4.9%) w…
Are Human P[14] Rotavirus Strains the Result of Interspecies Transmissions from Sheep or Other Ungulates That Belong to the Mammalian Order Artiodact…
2009
ABSTRACT A limited number of human G6P[14] rotavirus strains that cause gastroenteritis in humans have been isolated in Europe and Australia. The complete genome sequences were determined for five of these human strains—B10925-97 (isolated in Belgium in 1997), 111/05-27 (Italy, 2005), PA169 (Italy, 1987), MG6 (Australia, 1993), and Hun5 (Hungary, 1997)—and their genetic relatedness to animal rotavirus strains was evaluated by sequencing the complete genome of the sheep rotavirus OVR762 (G8P[14]; Spain, 2002), the guanaco ( Lama guanicoe ) rotavirus strains Arg/Chubut/99 and Arg/Río Negro/98 (G8P[14] and G8P[1], respectively; Argentina, 1999 and 1998), the sable antelope strain RC-18/08 (G6…
Heterogeneity and temporal dynamics of evolution of G1 human rotaviruses in a settled population.
2006
ABSTRACT A rotavirus sample collection from 19 consecutive years was used to investigate the heterogeneity and the dynamics of evolution of G1 rotavirus strains in a geographically defined population. Phylogenetic analysis of the VP7 gene sequences of G1P[8] human rotavirus strains showed the circulation of a heterogeneous population comprising three lineages and seven sublineages. Increases in the circulation of G1 rotaviruses were apparently associated with the introduction of novel G1 strains that exhibited multiple amino acid changes in antigenic regions involved in rotavirus neutralization compared to the strains circulating in the previous years. The emergence and/or introduction of G…
Canine-Origin G3P[3] Rotavirus Strain in Child with Acute Gastroenteritis
2007
Infection by an animal-like strain of rotavirus (PA260/97) was diagnosed in a child with gastroenteritis in Palermo, Italy, in 1997. Sequence analysis of VP7, VP4, VP6, and NSP4 genes showed resemblance to a G3P[3] canine strain identified in Italy in 1996. Dogs are a potential source of human viral pathogens.