Search results for " Primary"

Impact des allocations en ressources sur l'efficacité des écoles primaires en Côte d'Ivoire

2011

The quality of primary education in Côte d'Ivoire has deteriorated sharply over the past three decades. This situation is the result of an approximate management of the education system, which is characterized by a lack of educational support, a misallocation of resources, a congestion of classrooms (42 students for a teacher in primary school) and a lack of skilled and well trained teachers. In addition, the military-political conflict in September 2002 did not allow to improve this situation; on the contrary, it has further deteriorated the situation. Thus, the aim of this thesis is first to analyze the influence of resource endowments on the effectiveness of primary schools in Cote d'Ivo…

Cisplatin-induced endoreduplication in CHO cells: DNA damage and inhibition of topoisomerase II.

2006

It has been proposed that polyploid cells that arise during a variety of pathological conditions and as a result of exposure to genotoxicants, typically in the liver, become aneuploid through genetic instability. Aneuploidy contributes to, or even drives, tumour development. We have assessed the capacity of the drug cisplatin, one of the most commonly used compounds for the treatment of malignancies, to induce endoreduplication, a particular type of polyploidy, in cultured Chinese hamster AA8 cells. Taking into account that any interference with DNA topoisomerase II (topo II) function leads to endoreduplication, we have found that treatment of the cells with this platinum compound results i…

Characterization and phylogenetic analysis of a cDNA encoding the Fes/FER related, non-receptor protein-tyrosine kinase in the marine sponge Sycon ra…

1998

Abstract In search of ancient versions of phylogenetically conserved genes/proteins, which are typical for multicellular animals, we have decided to analyse marine sponges (Porifera), the most ancient and most primitive metazoan organisms. We report here the complete nucleotide sequence of Sycon raphanus cDNA coding for a 879 aa long protein (100 kDa), which displays high overall similarity in primary structure and organization of domains with non-receptor tyrosine kinases (TKs) from the Fes/FER family. The encoded protein, which we named Fes/FER_SR, has a highly conserved, 260 aa long tyrosine kinase domain at the C-terminus. Amino-terminal to the catalytic domain is an 85 aa long SH2 doma…

Integrēts latviešu valodas mācību saturs un tā metodika sākumskolā

1999

Análisis del papel de los maestros en el desarrollo de actividades de indagación en el practicum de primaria

2014

Resumen En este trabajo se examina el papel que juegan tres maestros en practicas en la aplicacion de actividades de indagacion en Primaria y como influye en su desarrollo. Para ello se analizan las grabaciones en video de estos docentes durante una actividad desarrollada en su practicum,  utilizando un sistema de categorias que tiene en cuenta: las fases didacticas como observacion o planteamiento de hipotesis,  las habilidades comunicativas como descripcion o preguntas, y quien realiza la accion (maestro o alumno). Los resultados muestran que los maestros en practicas encuentran dificultades ligadas a aspectos de: 1) estructuracion de las secuencias didacticas; 2) planteamiento de pregunt…

CREAPP K6-12: Tool to evaluate the creative potential of app oriented to the design of personal digital storytelling

2018

An instrument is presented that allows primary school teachers to evaluate the potentiality to develop creativity that have playful  online app K6-12 focused on the development of digital storytelling (DST), so they can select those that can be used in the classroom for that purpose. The instrument validated consists of 48 indicators associated with the six dimensions of the creativity: flexibility, originality, fluency, problem solving, elaboration of products and co-edition and dissemination. It was designed based on the opinions of experts in creativity and Information and Communication Technologies of the didactic field, theory of education and methodology; also with the assessments and…

Triple planes with $p_g=q=0$

2019

We show that general triple planes with p_g=q=0 belong to at most 12 families, that we call surfaces of type I,..., XII, and we prove that the corresponding Tschirnhausen bundle is direct sum of two line bundles in cases I, II, III, whereas is a rank 2 Steiner bundle in the remaining cases. We also provide existence results and explicit constructions for surfaces of type I,..., VII, recovering all classical examples and discovering several new ones. In particular, triple planes of type VII provide counterexamples to a wrong claim made in 1942 by Bronowski.

Are the new genetic tools for diagnosis of Wilson disease helpful in clinical practice?

2020

Summary The diagnosis of Wilson disease is not always easy. For many patients, a combination of tests reflecting disturbed copper metabolism may be needed. Testing for ATP7B variants has become part of the routine diagnostic approach. The methods of genetic testing include analysis of the 21 coding exons and intronic flanking sequences, in which exons with recurrent variants would be prioritised depending on the mutation frequency in the local population. If sequencing the entire ATP7B gene cannot identify 2 variants and the suspicion for Wilson disease is high, after reviewing the clinical data, WES (whole-exome sequencing) or WGS (whole-genome sequencing) could be applied. A workflow base…

Variables that Modulate Home Care Effectiveness in Patients with Chronic Cardiovascular Disease

2019

Introduction: The growing population of patients with chronic cardiovascular disease has many complex biomedical and psychosocial needs and requires an integrated teamwork approach. There is a need to develop a model for assessing the effectiveness of home care in patients with chronic cardiovascular disease, which would take the needs of informal caregivers into account.The purpose of the study was to determine the variables affecting the level of effectiveness of home care, defined as the co-occurrence of high: quality of life (QoL), health behaviours and met needs.Subjects and method: The study involved 193 patients under the care of district nurses and 161 informal caregivers. The study…

Subsidization of higher education versus expansion of primary enrollments : what can a shift of resources achieve in Sub-Saharan Africa ?

1985

International audience; In many LDCs today, the distribution of public resources for education tends to be inefficient and inequitable in that subsidization often increases rather than decreases with the level of education. To improve efficiency and equity, a shift of resources from higher to primary education should therefore be considered. Such a shift would obviously imply an increase in the private cost of higher education, but its effect could be mitigated through a loan scheme. In this paper, our main purpose is to show what a cut in subsidies to higher education can achieve in terms of expanding primary enrollments. The results show that although the outcome differs from country to c…