Search results for " Psychiatry and Mental Health"

showing 10 items of 109 documents

Acetylcholinesterase inhibitors and memantine in bipolar disorder: A systematic review and best evidence synthesis of the efficacy and safety for mul…

2016

Abstract Background Acetylcholinesterase inhibitors (AceI) and memantine might prove useful in bipolar disorder (BD) given their neuroprotective and pro-cognitive effects, as highlighted by several case reports. We aimed to systematically review the efficacy and safety of AceI and memantine across multiple outcome dimensions in BD. Methods Systematic PubMed and SCOPUS search until 04/17/2015 without language restrictions. Included were randomized controlled trials (RCTs), open label studies and case series of AceI or memantine in BD patients reporting quantitative data on depression, mania, psychotic symptoms, global functioning, or cognitive performance. We summarized results using a best-…

Malelaw.inventionpsychosis.0302 clinical medicinePiperidinesRandomized controlled triallawDonepezilDonepezilRandomized Controlled Trials as Topicbipolar disorderClinical Trials as TopicEvidence-Based MedicineDepressionMemantineMiddle AgedManiaPsychiatry and Mental healthClinical PsychologyTreatment Outcomeacetylcholinesterase inhibitorsdepressionIndansFemalemedicine.symptomPsychologyManiamedicine.drugAdultmedicine.medical_specialtyBipolar disorderPlaceboBipolar disorder Acetylcholinesterase inhibitors Memantine Depression Mania Psychosis03 medical and health sciencesmaniaMemantineInternal medicinemedicineGalantamineHumansBipolar disorderAcetylcholinesterase inhibitors; Bipolar disorder; Depression; Mania; Memantine; Psychosis.PsychiatryDepressive DisorderGalantaminePsychosismedicine.disease030227 psychiatryAcetylcholinesterase inhibitorsMoodPsychotic DisordersAcetylcholinesterase inhibitors; Bipolar disorder; Depression; Mania; Memantine; Psychosis; Psychiatry and Mental Health; Clinical PsychologyCase-Control StudiesmemantineCholinesterase InhibitorsExcitatory Amino Acid Antagonists030217 neurology & neurosurgeryJournal of Affective Disorders
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Aspirin and incident depressive symptoms: A longitudinal cohort study over 8 years

2017

Objective: Aspirin exhibits anti-atherosclerotic and anti-inflammatory properties—two potential risk factors for depression. The relationship between aspirin use and depression, however, remains unclear. We investigated whether the aspirin use is associated with a decreased incidence of depressive symptoms in a large North American cohort. Methods: Data from the Osteoarthritis Initiative dataset, a multicenter, longitudinal study on community-dwelling adults was analyzed. Aspirin use was defined through self-report in the past 30 days and confirmed by a trained interviewer. Incident depressive symptoms were defined as a score of ≥16 in the 20-item Center for Epidemiologic Studies-Depression…

Malemedicine.medical_specialtyLongitudinal studyEpidemiologyAspirin; Cohort; Depression; Epidemiology; Psychiatry; Survey; Geriatrics and Gerontology; Psychiatry and Mental Healthaspirin cohort depression epidemiology psychiatry surveyArticle03 medical and health sciences0302 clinical medicine*aspirinFibrinolytic AgentsInternal medicineMedicineHumansLongitudinal Studies*epidemiologySurveyAgedProportional Hazards Models*surveyPsychiatryAspirinDepressive Disorder*cohortAspirinbusiness.industryProportional hazards modelDepressionIncidence (epidemiology)IncidenceHazard ratioAnti-Inflammatory Agents Non-SteroidalCohortMiddle Aged030227 psychiatryPsychiatry and Mental Health*psychiatryCohortPropensity score matchingPhysical therapyRegression AnalysisFemaleGeriatrics and Gerontologybusiness*depression030217 neurology & neurosurgeryFibrinolytic agentmedicine.drug
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Acetylcholinesterase inhibitors are associated with weight loss in older people with dementia: A systematic review and meta-analysis

2016

We conducted a systematic review and meta-analysis investigating the influence of acetylcholinesterase inhibitors (AChEIs) therapy on nutritional status and weight across observational and interventional studies. Two authors searched major electronic databases from inception until 10/14/2015 for longitudinal, open-label and randomised double-blind placebo controlled (randomised controlled trials (RCTs)) studies of AChEIs in patients with dementia reporting nutritional status outcome data. Out of 3551 initial hits, 25 studies (12 open-label trials, 9 RCTs and 4 longitudinal studies) including 10 792 patients with dementia were meta-analysed. In longitudinal studies (median follow-up 6 months…

Malemedicine.medical_specialtyPlaceboRisk Assessment03 medical and health sciences0302 clinical medicineArts and Humanities (miscellaneous)Weight lossAlzheimer DiseaseInternal medicineWeight LossmedicineDementiaHumansCumulative incidence030212 general & internal medicineAgedRandomized Controlled Trials as TopicGeriatricsbusiness.industryDEMENTIAmedicine.diseaseMETA-ANALYSISALZHEIMER'S DISEASE; DEMENTIA; GERIATRICS; META-ANALYSIS; Neurology (clinical); Psychiatry and Mental Health; Surgery; Arts and Humanities (miscellaneous)Acetylcholinesterase inhibitorsALZHEIMER'S DISEASEPsychiatry and Mental HealthMeta-analysisPhysical therapyObservational studyFemaleSurgeryCholinesterase InhibitorsNeurology (clinical)medicine.symptombusinessOlder peopleGERIATRICS030217 neurology & neurosurgery
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Rates and correlates of suicidal ideation among stroke survivors: a meta-Analysis

2017

BACKGROUND: A better understanding of the epidemiological impact of suicidal ideation after stroke is required to identify subjects needing personalised interventions. OBJECTIVE: The aim of this meta-analysis was to estimate rates and correlates of suicidal ideation among stroke survivors. METHODS: We searched via Ovid, Medline, Embase and PsycInfo from database inception until August 2016. Predefined outcomes were (1) rates of suicidal ideation based on random-effects pooled proportion and (2) relevant sociodemographic and clinical correlates, using random-effects odds ratio (OR) or standardised mean difference (SMD) for categorical and continuous variables, respectively. RESULTS: Fifteen …

Malemedicine.medical_specialtyStatistics as TopicMEDLINEPsychological interventionPsycINFOmeta-analysisurgery03 medical and health sciences0302 clinical medicineRecurrenceEpidemiologyOdds RatiomedicineHumansSurvivors030212 general & internal medicinePsychiatryStrokeSuicidal ideationSettore MED/25 - PsichiatriaAgedarts and humanitiesDepressive DisorderneurologyOdds ratioMiddle Agedmedicine.diseasestrokedepression; epidemiology; meta-analysis; stroke; suicidal ideation; surgery; arts and humanities ; neurology; psychiatry and mental healthmeta-analysissuicidal ideationpsychiatry and mental healthObservational Studies as TopicCross-Sectional StudiesMeta-analysisdepressionFemaleSettore MED/26 - NeurologiaepidemiologyNeurology (clinical)medicine.symptomPsychology030217 neurology & neurosurgeryClinical psychology
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Nicotine enhances antisaccade performance in schizophrenia patients and healthy controls

2013

Abstract Nicotine has been proposed to be a cognitive enhancer, particularly in schizophrenia patients. So far, the published studies of nicotine effects on antisaccade performance in schizophrenia patients only tested participants who were deprived smokers. Thus, we aimed to test both smoking and non-smoking patients as well as healthy controls in order to extend previous findings. Moreover, we employed a paradigm using standard and delayed trials. We hypothesized that, if nicotine is a genuine cognitive enhancer, its administration would improve antisaccade performance both in smoking and non-smoking participants. A total of 22 patients with schizophrenia (12 smokers and 10 non-smokers) a…

Malemedicine.medical_treatmentStatistics as TopicNicotine2738 Psychiatry and Mental Health0302 clinical medicine2736 Pharmacology (medical)Pharmacology (medical)Nicotinic AgonistsCotinineCross-Over StudiesSmokingCognitionMiddle Aged16. Peace & justice3. Good healthPsychiatry and Mental healthNicotinic acetylcholine receptor3004 PharmacologySchizophreniaFemaleSmoking statusPsychologymedicine.drugClinical psychologyAdultNicotinemedicine.medical_specialtyAdolescentNicotine patch610 Medicine & healthAdministration CutaneousYoung Adult03 medical and health sciencesDouble-Blind MethodInternal medicineReaction TimeSaccadesmedicineHumansEffects of sleep deprivation on cognitive performanceBeneficial effectsPharmacologyAnalysis of Variancemedicine.disease030227 psychiatryElectrooculography10054 Clinic for Psychiatry Psychotherapy and PsychosomaticsSchizophrenia030217 neurology & neurosurgery
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DSM-IV Combined Type ADHD Shows Familial Association With Sibling Trait Scores

2008

Contains fulltext : 69060.pdf (Publisher’s version ) (Closed access) Attention deficit hyperactivity disorder (ADHD) is a discrete clinical syndrome characterized by the triad of inattention, hyperactivity, and impulsivity in the context of marked impairments. Molecular genetic studies have been successful in identifying genetic variants associated with ADHD, particularly with DSM-IV inattentive and combined subtypes. Quantitative trait locus (QTL) approaches to linkage and association mapping have yet to be widely used in ADHD research, although twin studies investigating individual differences suggest that genetic liability for ADHD is continuously distributed throughout the population, u…

Malequantitative geneticsGenetics and epigenetic pathways of disease [NCMLS 6]Genetic Linkageattention deficit hyperactivity disorder (ADHD)GENOMEWIDE SCANMedizin2804 Cellular and Molecular NeuroscienceNeuroinformatics [DCN 3]MULTIPLE-REGRESSION ANALYSIS2738 Psychiatry and Mental Health0302 clinical medicineDIFFICULTIES QUESTIONNAIREDEFICIT-HYPERACTIVITY DISORDERTwins DizygoticPerception and Action [DCN 1]Genetics(clinical)DF analysisAssociation mappingGenetics (clinical)linkage studyGeneticseducation.field_of_studyATTENTION-DEFICIT/HYPERACTIVITY DISORDERDOPAMINE TRANSPORTER GENE10058 Department of Child and Adolescent PsychiatryDiagnostic and Statistical Manual of Mental DisordersPsychiatry and Mental healthCHILD-BEHAVIOR CHECKLISTConduct disorderRegression AnalysisFemalemedicine.symptomFunctional Neurogenomics [DCN 2]Clinical psychology2716 Genetics (clinical)Quantitative Trait LociPopulation610 Medicine & healthQuantitative trait locusBiologyImpulsivityMental health [NCEBP 9]behavioral disciplines and activitiesINDIVIDUAL-DIFFERENCESInterviews as TopicGenomic disorders and inherited multi-system disorders [IGMD 3]quantitative trait locus (QTL)03 medical and health sciencesCellular and Molecular NeuroscienceCognitive neurosciences [UMCN 3.2]mental disordersmedicineHumansSibling RelationsAttention deficit hyperactivity disorderFamilyGenetic Predisposition to Diseaseddc:610Medizinische Fakultät » Universitätsklinikum Essen » LVR-Klinikum Essen » Klinik für Psychiatrie Psychosomatik und Psychotherapie des Kindes- und JugendaltersSiblingeducationTWIN DATAmedicine.diseaseTwin study030227 psychiatryGenetic defects of metabolism [UMCN 5.1]Attention Deficit Disorder with HyperactivityCONDUCT DISORDER030217 neurology & neurosurgeryAmerican Journal of Medical Genetics. Part B: Neuropsychiatric Genetics
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Visual–spatial training efficacy in children affected by migraine without aura: a multicenter study

2017

Francesco Precenzano,1,* Maria Ruberto,2,* Lucia Parisi,3 Margherita Salerno,4 Agata Maltese,3 Beatrice Gallai,5 Rosa Marotta,6 Serena Marianna Lavano,7 Francesco Lavano,6 Michele Roccella3 1Clinic of Child and Adolescent Neuropsychiatry, Headache Center for Children and Adolescent. Department of Mental and Physical Health and Preventive Medicine, Università degli Studi della Campania Luigi Vanvitelli, 2Department of Medical-Surgical and Dental Specialties, Università degli Studi della Campania Luigi Vanvitelli, Naples, 3Department of Psychological, Pedagogical and Educational Sciences, 4Sciences for Mother and Child Health Promotion, University of Palermo, Palermo, 5D…

Migraine without aura; Visual–motor integration; Visual–motor training skills;medicine.medical_specialtyNeuropsychiatric Disease and TreatmentAuraMigraine without aura; Visual–motor integration; Visual–motor training skills; Psychiatry and Mental Health; Biological PsychiatryAudiologyGroup BVisual–motor training skill03 medical and health sciencesSettore M-PSI/04 - Psicologia Dello Sviluppo E Psicologia Dell'Educazione0302 clinical medicineVisual–motor integrationMedicinePsychiatryBiological PsychiatryOriginal ResearchVisual–motor training skillsbusiness.industryMean ageCognitionmedicine.diseaseSettore MED/39 - Neuropsichiatria Infantile030227 psychiatryClinical PracticeMulticenter studyMigrainePsychiatry and Mental HealthMigraine without auraPopulation studybusiness030217 neurology & neurosurgeryNeuropsychiatric Disease and Treatment
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Part 3. A question of perspective: The association between intrusive thoughts and obsessionality in 11 countries

2014

Abstract A key assumption of contemporary cognitive-behavioral models of obsessive–compulsive disorder (OCD) is that obsessional thoughts exist on a continuum with “normal” unwanted intrusive thoughts. Recently, however, some authors have challenged this notion. The present study aimed to clarify (a) the extent that different types of intrusive thoughts in nonclinical individuals are associated with obsessionality, (b) the relative contribution of frequency, distress and control ratings to obsessionality, and (c) the extent that existing findings (primarily from North American or European samples) generalize to other countries in the world. Five hundred and fifty-four non clinical individua…

OCDObsessive compulsive inventory[SHS.PSY]Humanities and Social Sciences/PsychologyIntrusive thoughts; Obsessionality; Obsessions; Obsessive-compulsive inventory-revised; OCD; Clinical Psychology; Psychiatry and Mental HealthVulnerability factorIntrusive thoughtsObsessionsObsessive-compulsive inventory-revisedDistressClinical PsychologyNon clinicalObsessionalityPsychiatry and Mental HealthPerceived controlObsessional thoughtsPsychologyComputingMilieux_MISCELLANEOUSClinical psychology
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Parent of origin effects in attention/deficit hyperactivity disorder (ADHD): analysis of data from the international multicenter ADHD genetics (IMAGE…

2008

Contains fulltext : 71540.pdf (Publisher’s version ) (Closed access) There are conflicting reports suggesting that the parental origin of transmitted risk alleles may play a role in the etiology of attention deficit/hyperactivity disorder (ADHD). A recent report by Hawi and colleagues observed a generalized paternal over-transmission of alleles associated with ADHD. This was not replicated in more recent studies. Using data from a large multicenter study we examined the overall and gene-specific parent of origin effect in 554 independent SNPs across 47 genes. Transmission disequilibrium and explicit parent of origin test were performed using PLINK. Overall parent of origin effect was tested…

ParentsCandidate geneGenetics and epigenetic pathways of disease [NCMLS 6]2804 Cellular and Molecular NeuroscienceMedizinNeuroinformatics [DCN 3]Linkage Disequilibrium2738 Psychiatry and Mental Health0302 clinical medicineRisk FactorsPerception and Action [DCN 1]Genetics(clinical)Genetics (clinical)0303 health sciencesTPH210058 Department of Child and Adolescent PsychiatryPsychiatry and Mental healthData Interpretation StatisticalFunctional Neurogenomics [DCN 2]Clinical psychologyGenetic Markers2716 Genetics (clinical)Single-nucleotide polymorphism610 Medicine & healthMental health [NCEBP 9]Polymorphism Single NucleotideGenetic determinismGenomic disorders and inherited multi-system disorders [IGMD 3]Molecular epidemiology [NCEBP 1]03 medical and health sciencesCellular and Molecular NeuroscienceCognitive neurosciences [UMCN 3.2]Translational research [ONCOL 3]medicineAttention deficit hyperactivity disorderHumansFamilyGenetic Predisposition to Diseaseddc:610Medizinische Fakultät » Universitätsklinikum Essen » LVR-Klinikum Essen » Klinik für Psychiatrie Psychosomatik und Psychotherapie des Kindes- und JugendaltersAlleleAlleles030304 developmental biologyChi-Square DistributionEndocrinology and reproduction [UMCN 5.2]business.industrymedicine.diseaseGenetic defects of metabolism [UMCN 5.1]Multicenter studyAttention Deficit Disorder with HyperactivityEtiologybusiness030217 neurology & neurosurgeryAmerican journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
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Intelligence in DSM-IV combined type attention-deficit/hyperactivity disorder is not predicted by either dopamine receptor/transporter genes or other…

2008

Contains fulltext : 69677.pdf (Publisher’s version ) (Closed access) A major goal of genetic studies of attention deficit hyperactivity disorder (ADHD) is to identify individual characteristics that might help segregate the disorder's inherent heterogeneity. [Mill et al. (2006); Arch Ger Psychiatry 63:462-469] recently reported a potentially important association between two dopamine-related risk polymorphisms (DRD4 variable number tandem repeat (VNTR) in exon 3 and DAT1 VNTR in the 3' UTR) and lowered IQ in ADHD. The objective of the current study was to replicate the [Mill et al. (2006); Arch Ger Psychiatry 63:462-469] findings in a clinical sample and to extend the analysis to a large ra…

ProbandMaleGenetics and epigenetic pathways of disease [NCMLS 6]Intelligence2804 Cellular and Molecular NeuroscienceMedizinNeuroinformatics [DCN 3]Receptors DopamineCohort Studies2738 Psychiatry and Mental Health0302 clinical medicineRisk FactorsPerception and Action [DCN 1]MedicineGenetics(clinical)ChildGenetics (clinical)10058 Department of Child and Adolescent Psychiatry3. Good healthVariable number tandem repeatPsychiatry and Mental healthChild PreschoolFemaleFunctional Neurogenomics [DCN 2]Clinical psychology2716 Genetics (clinical)AdolescentGenotypeSingle-nucleotide polymorphism610 Medicine & healthMental health [NCEBP 9]Genomic disorders and inherited multi-system disorders [IGMD 3]03 medical and health sciencesCellular and Molecular NeuroscienceCognitive neurosciences [UMCN 3.2]mental disordersAttention deficit hyperactivity disorderHumansGenetic Predisposition to Diseaseddc:610Medizinische Fakultät » Universitätsklinikum Essen » LVR-Klinikum Essen » Klinik für Psychiatrie Psychosomatik und Psychotherapie des Kindes- und JugendaltersAlleleRisk factorAssociation (psychology)AllelesDopamine Plasma Membrane Transport Proteinsbusiness.industrymedicine.disease030227 psychiatryGenetic defects of metabolism [UMCN 5.1]Genetic markerAttention Deficit Disorder with Hyperactivitybusiness030217 neurology & neurosurgery
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