Search results for " RED"

showing 10 items of 2272 documents

Reducing NAFLD-screening time: A comparative study of eight diagnostic methods offering an alternative to ultrasound scans.

2018

Background & Aims: The use of ultrasound scan (US) in non-alcoholic fatty liver disease (NAFLD) screening overloads US waiting lists. We hypothesized and tested a hybrid two-step method, consisting of applying a formula, to exclude subjects at low risk, before US. Methods: The sample included 2970 males and females (937 with NAFLD) diagnosed by US. We selected eight formulas: Fatty Liver Index (FLI), Hepatic Steatosis Index (HIS), body mass index (BMI), waist circumference (WC), Abdominal Volume Index (AVI), waist-to-height ratio (WHtR), waist/height0.5 (WHT.5R) and Body Roundness Index (BRI), and calculated their performance in the two-step method evaluating percentage reduction of the…

AdultMalemedicine.medical_specialtyDiagnostic methodsWaistGastroenterologyBody Mass Index03 medical and health sciences0302 clinical medicineNon-alcoholic Fatty Liver DiseaseRisk FactorsInternal medicineScreening methodMedicineHumansAgedUltrasonographyHepatologyAnthropometrybusiness.industryWaist-Hip RatioFatty liverUltrasoundnutritional and metabolic diseasesPercentage reductionMiddle Agedmedicine.diseasescreening NAFLDItalyROC Curve030220 oncology & carcinogenesis030211 gastroenterology & hepatologyFemaleSteatosisWaist CircumferencebusinessBody mass indexLiver international : official journal of the International Association for the Study of the Liver
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Postural instability of extremely obese individuals improves after a body weight reduction program entailing specific balance training

2005

The purposes of this study were to compare postural stability between obese and lean subjects and to investigate the effect of a 3-week body weight reduction (BWR) program entailing specific balance training on postural stability of extremely obese patients. Time of balance maintenance and mean error on the medial-lateral direction at the trunk and lower limb level were assessed during a single limb stance on a movable platform in 19 non-obese and in 20 extremely obese individuals (age range: 20-40 yr). Time of balance maintenance was shorter (obese: 21.1+/-7.7 vs lean: 27.3+/-3.1 sec) and medial-lateral sway of the trunk was larger in obese (5.4+/-3.2 degrees) than in lean (3.2+/-1.1 degre…

AdultMalemedicine.medical_specialtyDiet ReducingEndocrinology Diabetes and Metabolismmedicine.medical_treatmentPostureBalance trainingPhysical exerciseOverweightBody weightEndocrinologyWeight LossmedicineHumansObesityPostural BalanceBalance (ability)Rehabilitationbusiness.industrymedicine.diseaseObesityTrunkPhysical FitnessPhysical therapyFemalemedicine.symptombusiness
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Body Composition and Power Performance Improved After Weight Reduction in Male Athletes Without Hampering Hormonal Balance

2014

The aim of this study was to investigate the effects of a 4-week weight reduction period with high protein and reduced carbohydrate intake on body composition, explosive power, speed, serum hormones, and acid-base balance in male track and field jumpers and sprinters. Eight participants were assigned to a high weight reduction group (HWR; energy restriction 750 kcal·d) and 7 to a low weight reduction group (LWR; energy restriction 300 kcal·d). Energy and carbohydrate intake decreased significantly (p ≤ 0.05) only in HWR by 740 ± 330 kcal·d and 130 ± 29 g·d, respectively. Furthermore, total body mass and fat mass decreased (p ≤ 0.05) only in HWR by 2.2 ± 1.0 kg and 1.7 ± 1.6 kg, respectively…

AdultMalemedicine.medical_specialtyDiet ReducingHydrocortisoneGlobulinPhysical Therapy Sports Therapy and RehabilitationDiet Carbohydrate-RestrictedSex hormone-binding globulinWeight lossSex Hormone-Binding GlobulinInternal medicineWeight LossmedicineHumansTestosteroneOrthopedics and Sports Medicineta315Balance (ability)HydrocortisoneAcid-Base EquilibriumbiologyChemistryTrack and FieldGeneral MedicineCarbohydrateexplosive powerEndocrinologySprintBody Compositionbiology.proteinDietary Proteinsmedicine.symptomproteinBiomarkersHormonemedicine.drugJournal of Strength and Conditioning Research
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Influence of exercise training on physiological and performance changes with weight loss in men.

1999

The purpose of this study was to examine the physiological effects of a weight-loss dietary regimen with or without exercise.Thirty-five overweight men were matched and randomly placed into either a control group (C; N = 6) or one of three dietary groups; a diet-only group (D; N = 8), a diet group that performed aerobic exercise three times per week (DE; N = 11); and a diet group that performed both aerobic and strength training three times per week (DES; N = 10).After 12 wk, D, DE, and DES demonstrated a similar and significant (Por = 0.05) reduction in body mass (-9.64, -8.99, and -9.90 kg, respectively) with fat mass comprising 69, 78, and 97% of the total loss in body mass, respectively…

AdultMalemedicine.medical_specialtyDiet ReducingPhysical Therapy Sports Therapy and RehabilitationPhysical exerciselaw.inventionBody Mass IndexOxygen ConsumptionRandomized controlled triallawWeight lossWeight LossMedicineHumansOrthopedics and Sports MedicineObesityExercise physiologyExerciseAnalysis of Variancebusiness.industrymedicine.diseaseObesityLipidsPhysical therapyBody CompositionRegression AnalysisAnalysis of variancemedicine.symptombusinessDietary regimenBody mass indexMedicine and science in sports and exercise
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Effects of Rapid Weight Reduction on Force Production and Vertical Jumping Height

1987

The effects of three weight reduction methods on maximal strength, rate of force development, vertical jumping height, and mechanical power were studied in track and field athletes and volleyball players. The three methods were sauna, diet with diuretic, and diuretic alone. The reductions in weight achieved were 3.4%, 5.8%, and 3.8% of body weight after sauna, diet + diuretic, and diuretic, respectively (P less than 0.001). Maximal isometric leg strength and the rate of isometric force development were decreased after the sauna and diet + diuretic treatments. Dehydration caused by the diuretic method alone did not impair neuromuscular performances. As had been expected from theoretical calc…

AdultMalemedicine.medical_specialtyDiet Reducingmedicine.medical_treatmentDiuresisPhysical Therapy Sports Therapy and RehabilitationIsometric exercisemedicine.disease_causeBody weightSteam BathJumpingWeight lossIsometric ContractionInternal medicinemedicineHumansOrthopedics and Sports MedicineChemistryBody WeightTrack and FieldWork (physics)Vertical jumpingDiuresisEndocrinologyPhysical Fitnessmedicine.symptomDiureticMuscle ContractionInternational Journal of Sports Medicine
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Effects of red orange juice intake on endothelial function and inflammatory markers in adult subjects with increased cardiovascular risk

2012

BACKGROUND Oxidative and inflammatory stresses are involved in the pathogenesis of atherosclerosis. The consumption of fruit and vegetables is associated with improved health and reduced cardiovascular risk. Red oranges have a high content of antioxidant and antiinflammatory substances, but there is a paucity of data concerning their effects on cardiovascular biomarkers in subjects with increased cardiovascular risk. OBJECTIVE We investigated the effect of red orange juice intake on endothelial function, oxidative stress, and markers of inflammation in subjects with increased cardiovascular risk. DESIGN Nineteen nondiabetic subjects with increased cardiovascular risk (aged 27-56 y) were inc…

AdultMalemedicine.medical_specialtyEndotheliumAnti-Inflammatory AgentsMedicine (miscellaneous)Inflammationmedicine.disease_causePlaceboAntioxidantsBeveragesYoung AdultRisk FactorsInternal medicineDiabetes mellitusDiabetes MellitusmedicineBody Fat DistributionHumansSingle-Blind MethodEndotheliumSettore MED/49 - Scienze Tecniche Dietetiche Applicateendothelial function cardiovascular risk red oranges inflammation FMDAgedInflammationOrange juiceCross-Over StudiesNutrition and DieteticsbiologyInterleukin-6Tumor Necrosis Factor-alphabusiness.industryC-reactive proteinMiddle Agedmedicine.diseaseCrossover studyOxidative StressC-Reactive ProteinEndocrinologymedicine.anatomical_structureCardiovascular DiseasesFruitbiology.proteinFemalemedicine.symptombusinessBiomarkersOxidative stressCitrus sinensis
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Coadministration of atorvastatin prevents nitroglycerin-induced endothelial dysfunction and nitrate tolerance in healthy humans.

2010

Objectives We aimed to assess whether concurrent administration of atorvastatin would modify the development of tolerance and endothelial dysfunction associated with sustained nitroglycerin (GTN) therapy in humans. Background Animal studies have demonstrated that administration of 3-hydroxy-3 methylglutaryl coenzyme A reductase inhibitors can protect against GTN-induced endothelial dysfunction and tolerance, likely through an antioxidant mechanism. Methods Thirty-six healthy male volunteers were randomized to receive continuous transdermal GTN (0.6 mg/h) and placebo, atorvastatin (80 mg/day) alone, or continuous transdermal GTN (0.6 mg/h) with concurrent atorvastatin (80 mg/day), all for 7 …

AdultMalemedicine.medical_specialtyEndotheliumendotheliumAdolescentBrachial Arterymedicine.medical_treatmentAtorvastatinVasodilator AgentsBlood PressurePlaceboNitroglycerinYoung AdultDouble-Blind MethodHeart RateReference ValuesInternal medicinemedicineAtorvastatinHumansPyrrolesEndothelial dysfunctionSalinetolerancebiologybusiness.industryDrug Administration RoutesDrug Tolerancemedicine.diseaseVasodilationOxidative StressBlood pressuremedicine.anatomical_structureEndocrinologyHeptanoic AcidsCirculatory systemHMG-CoA reductasebiology.proteincardiovascular systemlipids (amino acids peptides and proteins)Endothelium VascularHydroxymethylglutaryl-CoA Reductase InhibitorsCardiology and Cardiovascular Medicinebusinessmedicine.drugcirculatory and respiratory physiologyJournal of the American College of Cardiology
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Domains of Physical Activity in Relation to Stiffness Index in the General Population.

2021

Background Regular exercise training represents an important modifier of arterial stiffness (AS). Therefore, sex‐specific relations between domains of physical activity (PA; commuting, domestic, and leisure‐time PA, including active sport and occupational PA) with AS were investigated. Methods and Results Stiffness index by digital photoplethysmography was investigated in 12 650 subjects from the GHS (Gutenberg Health Study). Self‐reported PA was evaluated by the “Short Questionnaire to Assess Health‐Enhancing Physical Activity” and reported as activity score peer week, being a combined measure of duration, frequency, and intensity of PA. Multivariable linear regression analysis demonstrat…

AdultMalemedicine.medical_specialtyEpidemiologyPopulationPhysical activityStiffness indexphysical activityPopulation basedRisk Assessmentpopulation basedPhysical medicine and rehabilitationSex FactorsVascular StiffnessRegular exerciseRisk FactorsGermanystiffness indexmedicineHumansHealthy LifestyleProspective StudiesPreventive CardiologyeducationExerciseOriginal Researcheducation.field_of_studybusiness.industryMiddle AgedProtective Factorsmedicine.diseaseLifestylemortalityPrimary PreventionCross-Sectional StudiesCardiovascular DiseasesArterial stiffnessPhysical EnduranceFemaleCardiology and Cardiovascular MedicinebusinessRisk Reduction Behaviorarterial complianceJournal of the American Heart Association
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Enhanced reduction in oxidative stress and altered glutathione and thioredoxin system response to unsaturated fatty acid load in familial hypercholes…

2014

Abstract Objectives Familial hypercholesterolemia (FH) is characterized by increased oxidative stress (OS) levels. In the postprandial state, lipids and lipoproteins modulate OS status through their impact on pro-oxidant and antioxidant mechanisms. The objective of this study was to evaluate in patients with FH the response to an unsaturated oral fat load test (OFLT) by analyzing the mRNA levels of genes involved in the glutathione and thioredoxin antioxidant systems. Design and Methods We analyzed 14 FH patients and 20 normolipidemic and normoglycemic controls. In both groups, mRNA values of antioxidant enzyme genes (glutathione and thioredoxin systems) were determined at baseline and at 2…

AdultMalemedicine.medical_specialtyGPX1Antioxidantmedicine.medical_treatmentGlutamate-Cysteine LigaseClinical Biochemistrymedicine.disease_causeGPX4Gene Expression Regulation EnzymologicGlutathione SynthaseHyperlipoproteinemia Type IIchemistry.chemical_compoundThioredoxinsDietary Fats UnsaturatedInternal medicinemedicineHumansUnsaturated fatty acidGlutathione PeroxidaseChemistryReverse Transcriptase Polymerase Chain ReactionGeneral MedicineGlutathioneFastingMiddle AgedPhospholipid Hydroperoxide Glutathione PeroxidaseGlutathioneOxidative StressPostprandialEndocrinologyGlutathione ReductaseFemaleThioredoxinOxidation-ReductionOxidative stressClinical biochemistry
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Effect of sperm glutathione peroxidases 1 and 4 on embryo asymmetry and blastocyst quality in oocyte donation cycles

2005

Objective To prospectively determine the impact of concrete components of the sperm oxidative glutathione stress system in terms of enzymatic activity and mitochondrial RNA (mRNA) expression on embryo quality and reproductive outcome. Human spermatozoa use the glutathione system to inactivate reactive oxygen metabolites, and there is a close correlation between some components of the glutathione system and male fertility. However, very few data are published regarding this system in sperm cells and its effect on fertilization ability and embryo development in human beings. Design An oocyte-donation model, used to homogenize the female factor. Setting University-affiliated private IVF settin…

AdultMalemedicine.medical_specialtyGPX1Glutathione reductaseFertilization in VitroBiologyGPX4Andrologychemistry.chemical_compoundGlutathione Peroxidase GPX1PregnancymedicineHumansCells CulturedGynecologychemistry.chemical_classificationGlutathione PeroxidaseOocyte Donationurogenital systemGlutathione peroxidaseObstetrics and GynecologyEmbryoGlutathioneMiddle AgedEmbryo MammalianPhospholipid Hydroperoxide Glutathione PeroxidaseSpermatozoaSpermBlastocystReproductive MedicinechemistryFemaleEmbryo qualityFertility and Sterility
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