Search results for " RESISTANCE"
showing 10 items of 2791 documents
Comparison of frictional resistance between passive self-ligating brackets and slide-type low-friction ligature brackets during the alignment and lev…
2019
Background To compare the frictional resistance between passive self-ligating brackets and conventional brackets with low-friction ligature under bracket/archwire and root/bone interface during dental alignment and leveling. Material and methods A tridimensional model of the maxilla and teeth of a patient treated with conventional brackets, and slide ligatures was generated employing the SolidWorks modeling software. SmartClip self-ligating brackets and Logic Line conventional brackets were assembled with slide low-friction ligatures, utilizing archwires with different diameters and alloys used for the alignment and leveling stage. Friction caused during the bracket/archwire interface and s…
New Modalities in Knee Osteoarthritis Treatment Using Autologous Bone Marrow-Derived Mononuclear Cells
2018
Abstract The clinical effects on knee osteoarthritis (OA) symptoms and tissue structure were evaluated after bone marrow-derived mononuclear cell intraarticular injection. A group of 32 patients with 34 knee joints in stage II–III osteoarthritis were treated by intraarticular injection of mononuclear cell suspension. Clinical results were obtained by KOOS (Knee Osteoarthritis Outcome Score) and KSS (Knee Society Score) scores during a 12 months follow-up period. Radiological evaluation was performed using magnetic resonance imaging. A comparison with a control group of 28 patients treated with routinely used three hyaluronic acid intra-articular injections was made. No adverse effects were …
An update on the relationships between rheumatoid arthritis and atherosclerosis
2010
Rheumatoid arthritis is a chronic inflammatory disease. Cardiovascular events are the most important cause of mortality and morbidity in patients with rheumatoid arthritis. Beyond the traditional cardiovascular risk factors, chronic systemic inflammation has been shown to be a crucial factor in atherosclerosis development and progression from endothelial dysfunction to plaque rupture and thrombosis. Many studies have shown that atherosclerosis is not a passive event like accumulation of lipids in the vessel walls; by contrast, it represents an active inflammation of the vessels. Inflammatory cells such as macrophages, monocytes and T cells play important roles in the development of both rhe…
Stiffness and Reinforcement Effect of electrical Resistance Strain Gauges
2007
: The increasing use of low-modulus materials, on which the reinforcement effect of the electrical resistance strain gauge is not negligible, has re-opened the research interest into this issue. This study deals with the evaluation of stiffness, and of the strain gauge Young's modulus involved in the estimation of both the global and the local reinforcement effect; the relationship between the strain gauge stiffness and the local reinforcement effect is also analysed. In particular, the experimental technique used to determine the stiffness of some commercial strain gauges is described. The results show that the strain gauge stiffness alone does not permit an accurate evaluation of the loc…
Shorter recovery time following high-intensity interval training induced higher body fat loss among overweight women
2018
Background: High intensity interval training (HIIT) has been widely employed as an exercise protocol to reduce fat, and also in addition, interval recovery periods are the most important factors which can have great impact on weight loss. Therefore, the aim of this study was the evaluation of different recovery time between HIIT program on metabolic responses and weight loss in overweight women. Methods: Twenty-four overweight (BMI 29.5±3.5 kg/m2) volunteer women were randomly assigned into three groups (n=8/group) to study the effects of different recovery times: (group 1; HIIT with 60/60 activity-rest ratio (sec), group 2; HIIT with 60/30 activity-rest ratio (sec), and group 3 was set as …
Destroying the Shield of Cancer Stem Cells: Natural Compounds as Promising Players in Cancer Therapy
2022
In a scenario where eco-sustainability and a reduction in chemotherapeutic drug waste are certainly a prerogative to safeguard the biosphere, the use of natural products (NPs) represents an alternative therapeutic approach to counteract cancer diseases. The presence of a heterogeneous cancer stem cell (CSC) population within a tumor bulk is related to disease recurrence and therapy resistance. For this reason, CSC targeting presents a promising strategy for hampering cancer recurrence. Increasing evidence shows that NPs can inhibit crucial signaling pathways involved in the maintenance of CSC stemness and sensitize CSCs to standard chemotherapeutic treatments. Moreover, their limited toxici…
Targeting GSK3 and Associated Signaling Pathways Involved in Cancer
2020
Glycogen synthase kinase 3 (GSK-3) is a serine/threonine (S/T) protein kinase. Although GSK-3 originally was identified to have functions in regulation of glycogen synthase, it was subsequently determined to have roles in multiple normal biochemical processes as well as various disease conditions. GSK-3 is sometimes referred to as a moonlighting protein due to the multiple substrates and processes which it controls. Frequently, when GSK-3 phosphorylates proteins, they are targeted for degradation. GSK-3 is often considered a component of the PI3K/PTEN/AKT/GSK-3/mTORC1 pathway as GSK-3 is frequently phosphorylated by AKT which regulates its inactivation. AKT is often active in human cancer a…
Nevardarbīgās pretošanās izpausmes 21. gadsimta revolūciju gaitā
2015
Maģistra darba nosaukums ir „Nevardarbīgās pretošanās izpausmes 21.gadsimta revolūciju gaitā”. Darbā tika pētītas krāsainās revolūcijas Gruzijā, Ukrainā, Baltkrievijā un Krievijā. Gruzijā un Ukrainā krāsainās revolūcijas bijušas veiksmīgas, proti, tika gāzti pastāvošie režīmi, toties Baltkrievijā un Krievijā mēģinājumi gāzt pastāvošos režīmus cieta neveiksmi. Krāsainās revolūcijas ir fenomens, kas vēl nav pilnībā izpētīts, tomēr tām ir iezīmes, kas to atšķir no revolūcijām to klasiskajā izpratnē. Pirmkārt, tas ir nevardarbīgo pretošanās metožu pielietojums. Otrkārt, krāsainās revolūcijas bieži vien ir saistītas ar vēlēšanu procesu, proti, negodīgas vēlēšanas kļūst par sabiedrības masas mobi…
Betatrophin Levels Are Related to the Early Histological Findings in Nonalcoholic Fatty Liver Disease
2021
Betatrophin, a liver hormone, regulates glucose and lipid metabolism. We investigated the betatrophin levels in nonalcoholic fatty liver disease (NAFLD) and searched for any relationship with histological severity and metabolic parameters. Fifty males with NAFLD [Nonalcoholic Steatohepatitis (NASH) (n = 32)