Search results for " Radical"

showing 10 items of 757 documents

CCDC 2090126: Experimental Crystal Structure Determination

2021

Related Article: Chris Gendy, J. Mikko Rautiainen, Aaron Mailman, Heikki M. Tuononen|2021|Chem.-Eur.J.|27|14405|doi:10.1002/chem.202102804

1-[26-bis(propan-2-yl)phenyl]-2244-tetramethyl-5-[222-tris(trimethylsilyl)digermanylidene]pyrrolidine radicalSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 2090120: Experimental Crystal Structure Determination

2021

Related Article: Chris Gendy, J. Mikko Rautiainen, Aaron Mailman, Heikki M. Tuononen|2021|Chem.-Eur.J.|27|14405|doi:10.1002/chem.202102804

1-[26-bis(propan-2-yl)phenyl]-5-{[111333-hexamethyl-2-(trimethylsilyl)trisilan-2-yl]germanylidene}-2244-tetramethylpyrrolidine radicalSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 957913: Experimental Crystal Structure Determination

2014

Related Article: I. S. Morgan, A. Peuronen, M. M. Hanninen, R. Clerac, H. M. Tuononen|2014|Inorg.Chem.|53|33|doi:10.1021/ic402954p

1-phenyl-3-(pyridin-2-yl)-124-benzotriazin-4(1H)-yl radicalSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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Intermolecular oxidative dehydrogenative 3,3′-coupling of benzo[b]furans and benzo[b]thiophenes promoted by DDQ/H+: total synthesis of shandougenine B

2016

With an excess of a strong acid, 2,3-dichloro-5,6-dicyano-1,4-quinone (DDQ) is shown to promote metal-free intermolecular oxidative dehydrogenative (ODH) 3,3'-coupling of 2-aryl-benzo[b]furans and 2-aryl-benzo[b]thiophenes up to 92% yield as demonstrated with 9 substrates. Based on the analysis of oxidation potentials and molecular orbitals combined with EPR, NMR and UV-Vis observations, the studied reaction is initiated by a DDQ-substrate charge transfer complex and presumably proceeds via oxidation of the substrate into an electrophilic radical cation that further reacts with another molecule of a neutral substrate. The coupling reactivity can easily be predicted from the oxidation potent…

116 Chemical sciencesEFFICIENTfree radicalscoupling reactionsvapaat radikaalit010402 general chemistryPhotochemistry01 natural sciencesMedicinal chemistryCoupling reactionoxidative dehydrogenationC BOND FORMATIONSCHOLL REACTIONELECTRON-TRANSFERMolecular orbitalReactivity (chemistry)luonnonaineiden synteesiDIPHOSPHINE LIGANDSta116BASIS-SETSCATALYZED STEREOSELECTIVE REACTIONS010405 organic chemistryChemistryOrganic ChemistrykytkentäreaktiotSubstrate (chemistry)Total synthesishapettava dehydroganaatiolaskennallinen kemiaCharge-transfer complex0104 chemical sciencesRadical ionsynthesis of natural productsACIDElectrophileCATION-RADICALSHETEROCYCLESOrganic Chemistry Frontiers
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Synthesis, Stability and Relaxivity of TEEPO-Met: An Organic Radical as a Potential Tumour Targeting Contrast Agent for Magnetic Resonance Imaging

2018

Cancer is a widespread and life-threatening disease and its early-stage diagnosis is vital. One of the most effective, non-invasive tools in medical diagnostics is magnetic resonance imaging (MRI) with the aid of contrast agents. Contrast agents that are currently in clinical use contain metals, causing some restrictions in their use. Also, these contrast agents are mainly non-specific without any tissue targeting capabilities. Subsequently, the interest has notably increased in the research of organic, metal-free contrast agents. This study presents a new, stable organic radical, TEEPO-Met, where a radical moiety 2,2,6,6-tetraethylpiperidinoxide (TEEPO) is attached to an amino acid, methio…

116 Chemical sciencesPharmaceutical ScienceContrast Media01 natural sciencesAnalytical Chemistrylaw.inventionGLUCOSENuclear magnetic resonancePiperidineslawHeterocyclic CompoundsNeoplasmsDrug DiscoveryMoietymagneettitutkimusSpin labelElectron paramagnetic resonanceta116orgaaniset yhdisteetmedicine.diagnostic_testMolecular StructureChemistryPhantoms ImagingRelaxation (NMR)radicalsMagnetic Resonance Imaging3. Good healthChemistry (miscellaneous)Molecular MedicineMRIRadical010402 general chemistryvapaat radikaalitImaging phantomArticleCyclic N-OxidesvarjoainetutkimusnitroxidesmedicineAnimalsHumanscontrast agentstyppiyhdisteetPhysical and Theoretical Chemistrymethionine010405 organic chemistryOrganic ChemistryElectron Spin Resonance SpectroscopyMagnetic resonance imagingIN-VITRO3126 Surgery anesthesiology intensive care radiologynitroxides; radicals; methionine; contrast agents; MRI; NMR; EPRIn vitroNMRTRANSPORT0104 chemical sciencesREDUCTIONSPIN-LABEL1182 Biochemistry cell and molecular biologyEPRMolecules; Volume 23; Issue 5; Pages: 1034
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CCDC 2097024: Experimental Crystal Structure Determination

2021

Related Article: Anni I. Taponen, Awatef Ayadi, Manu K. Lahtinen, Itziar Oyarzabal, Sébastien Bonhommeau, Mathieu Rouzières, Corine Mathonière, Heikki M. Tuononen, Rodolphe Clérac, Aaron Mailman|2021|J.Am.Chem.Soc.|143|15912|doi:10.1021/jacs.1c07468

3-methylpyridinium-1235-dithiadiazolyl radical cation 77'88'-tetracyanoquinodimethane radical anion propanenitrile solvateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 2097023: Experimental Crystal Structure Determination

2021

Related Article: Anni I. Taponen, Awatef Ayadi, Manu K. Lahtinen, Itziar Oyarzabal, Sébastien Bonhommeau, Mathieu Rouzières, Corine Mathonière, Heikki M. Tuononen, Rodolphe Clérac, Aaron Mailman|2021|J.Am.Chem.Soc.|143|15912|doi:10.1021/jacs.1c07468

3-methylpyridinium-1235-dithiadiazolyl radical cation 77'88'-tetracyanoquinodimethane radical anionSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1834563: Experimental Crystal Structure Determination

2018

Related Article: Serhii Krykun, Vincent Croué, Magali Allain, Zoia Voitenko, Juan Aragó, Enrique Ortí, Sébastien Goeb, Marc Sallé|2018|J.Mater.Chem.C|6|13190|doi:10.1039/C8TC04730H

48-bis[45-bis(methylsulfanyl)-2H-13-dithiol-2-ylidene]-48-dihydrobenzo[12-b:45-b']bisthiophene radical cation hexafluorophosphate tetrahydrofuran solvateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 2182459: Experimental Crystal Structure Determination

2022

Related Article: Anni I. Taponen, Awatef Ayadi, Noora Svahn, Manu K. Lahtinen, Mathieu Rouzières, Rodolphe Clérac, Heikki M. Tuononen, Aaron Mailman|2022|Cryst.Growth Des.|22|7110|doi:10.1021/acs.cgd.2c00795

4-(1-n-butylpyridinium-3-yl)-1235-dithiadiazolyl radical trifluoromethanesulfonateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1863394: Experimental Crystal Structure Determination

2018

Related Article: Anni I. Taponen, Joanne W. L. Wong, Kristina Lekin, Abdeljalil Assoud, Craig M. Robertson, Manu Lahtinen, Rodolphe Clérac, Heikki M. Tuononen, Aaron Mailman, Richard T. Oakley|2018|Inorg.Chem.|57|13901|doi:10.1021/acs.inorgchem.8b02416

4-(3H-1235-diselenadiazol-4-yl)pyridine radicalSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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