Search results for " Regulation"

showing 10 items of 3187 documents

La patria potestad prorrogada y la patria potestad rehabilitada en el nuevo proyecto de ley de reforma de la legislación civil y procesal para el apo…

2021

It is intended to analyze and reflect in the present work about the institution of the extension of parental authority and parental authority rehabilitated in the new regulation in the Draft Law that reforms the civil and procedural legislation to support people with disabilities in the exercise of their legal capacity. In this project, the extended parental authority and the rehabilitated parental authority are eliminated from the scope of disability, following a criterion that demands the treatment of people with disabilities with the attention that their specific situation requires, eliminating a regime that seems contrary to the system of promoting the autonomy of adults with disabiliti…

:CIENCIAS JURÍDICAS [UNESCO]parental authorityrehabilitacióneliminating a regime that seems contrary to the system of promoting the autonomy of adults with disabilities. This study is linked and addressedas they will be affected by the reform and by the effect of the structural deficiencies suffered by the Justice system of our country. the present work about the institution of the extension of parental authority and parental authority rehabilitated in the new regulation in the Bill of Law that reforms the civil and procedural legislation to support people with disabilities in the exercise of its legal capacity. In this projectelimination 236 251eliminaciónrehabilitationPablo It is intended to analyze and reflect in the present work about the institution of the extension of parental authority and parental authority rehabilitated in the new regulation in the Draft Law that reforms the civil and procedural legislation to support people with disabilities in the exercise of their legal capacity. In this projectprojectproyectoUNESCO::CIENCIAS JURÍDICASthe extended parental authority and the rehabilitated parental authority are eliminated from the scope of disabilitypatria potestadExtensionwith the characteristics and needs of people with a severe intellectual disabilityas they will be affected by the reform and by the effect of the structural insufficiencies suffered by the Justice system of our country. Prórroga2070-8157 22082 Revista Boliviana de Derecho 584568 2021 32 8055222 La patria potestad prorrogada y la patria potestad rehabilitada en el nuevo proyecto de ley de reforma de la legislación civil y procesal para el apoyo a las personas con discapacidad (actual ley 8/2021) Tortajada Chardífollowing a criterion that demands the treatment of people with disabilities with the attention that their specific situation requireshealth care economics and organizations
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Pre-marital and pre-unional financial agreements and their circulation in the context of the new EU regulations 2016/1103 and 2016/1104

2021

Regulations (EU) 2016/1103 and 2016/1104 provide spouses and partners with the possibility to conclude agreements for the organization of their property regime but do not detail their content and structure. Moreover, while the possibility to conclude those agreements even prior to the marriage or the conclusion of a registered partnership is a valuable innovation in comparison with other European Regulations in family matters, some choices made by the European legislator on applicable law will likely be source of inconveniences. Furthermore, as for their recognition and enforcement in the participating Member States ? which will be based on the same rules enacted for decisions, authentic in…

:CIENCIAS JURÍDICAS [UNESCO]reglamentos UE 34 51where the jurisprudence of the Supreme Court is steadily opposed to their acceptance. : Pre-marital agreementswhile the possibility to conclude those agreements even prior to the marriage or the conclusion of a registered partnership is a valuable innovation in comparison with other European Regulations in family mattersPablo D. Regulations (EU) 2016/1103 and 2016/1104 provide spouses and partners with the possibility to conclude agreements for the organization of their property regime but do not detail their content and structure. Moreoversome choices made by the European legislator on applicable law will likely be source of inconveniences. FurthermoreEU regulationsacuerdos previos a la convivencialike ItalyUNESCO::CIENCIAS JURÍDICASas for their recognition and enforcement in the participating Member States ? which will be based on the same rules enacted for decisionsand court settlements ? attention should be paid to their admissibility in some of themAcuerdos prematrimoniales2386-4567 22661 Actualidad jurídica iberoamericana 587897 2021 15 8113547 Pre-marital and pre-unional financial agreements and their circulation in the context of the new EU regulations 2016/1103 and 2016/1104 BrunoPre-marital agreements [where the jurisprudence of the Supreme Court is steadily opposed to their acceptance.]authentic instrumentspre-unional agreements
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Jurisdiction by connection and proper administration of justice under eu regulations 1103/2016 and 1104/2016

2021

The author analyses the rules of jurisdiction by connection set by Articles 4 and 5 of Regulations No. 1103 and 1104 of 2016 in matters of property regimes of transnational couples, taking into account the objective of proper administration of justice pursued within EU Civil judicial cooperation. The Twin Regulations provide for appropriate procedural tools to facilitate concentration of jurisdiction before the courts of the same Member State, establishing an important role for the choice-of-court agreement, especially where property regime issues arise in connection with a matrimonial case or a partnership dissolution case. As we wait for the implementation of these rules by national and E…

:CIENCIAS JURÍDICAS [UNESCO]related actions 148 163establishing an important role for the choice-of-court agreementley de sucesiones2386-4567 22661 Actualidad jurídica iberoamericana 587897 2021 15 8113554 Jurisdiction by connection and proper administration of justice under eu regulations 1103/2016 and 1104/2016 Pía Gasperiniproperty regimesJurisdictionfamily lawtaking into account the objective of proper administration of justice pursued within EU Civil judicial cooperation. The Twin Regulations provide for appropriate procedural tools to facilitate concentration of jurisdiction before the courts of the same Member StateUNESCO::CIENCIAS JURÍDICASMaría The author analyses the rules of jurisdiction by connection set by Articles 4 and 5 of Regulations No. 1103 and 1104 of 2016 in matters of property regimes of transnational couplesregímenes económicosthe author also explores some possible drawbacks they may present. Competencialey de familiaespecially where property regime issues arise in connection with a matrimonial case or a partnership dissolution case. As we wait for the implementation of these rules by national and European courtsacciones relacionadas.succession law
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Primeras consideraciones a la Ley Orga?nica 3/2021, de 24 de marzo, de regulación de la eutanasia. el reconocimiento de un nuevo derecho

2021

The aim of this paper is to carry out a brief study of the recent Organic Law 3/2021, of March 24, on the regulation of euthanasia (BOE. March 25, 2021) approved in Spain, from a constitutional perspective, highlighting its main aspects. The matter under study is not exempt from controversy because it covers legal, medical and ethical considerations of great complexity.

:CIENCIAS JURÍDICAS [UNESCO]suicidio asistidolifeassisted suicidederechosdespenalizaciónCuthanasiaof March 24de 24 de marzode regulación de la eutanasia. el reconocimiento de un nuevo derecho Agut Garcíahighlighting its main aspects. The matter under study is not exempt from controversy because it covers legalvidaon the regulation of euthanasia (BOE. March 25UNESCO::CIENCIAS JURÍDICASdeath2021) approved in Spainrightsmuertedecriminalization 980 995María Teresa The aim of this paper is to carry out a brief study of the recent Organic Law 3/20212070-8157 22082 Revista Boliviana de Derecho 584568 2021 32 8055245 Primeras consideraciones a la Ley Orga?nica 3/2021from a constitutional perspectivemedical and ethical considerations of great complexity. Eutanasia
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Derecho de acceso a la información : el desafío de una sociedad guiada por la transparencia en el ordenamiento jurídico español

2021

This study will address the two aspects of rights linked to information, the right to information and the right to information, to end with the formulation of some conclusions that, distancing themselves from a mere summary, seek to encourage doctrinal and political debate on assumptions that, being peacefully settled, should be reformulated in light of the repeated crisis of transparency. For this, it will be articulated by addressing, first, the most significant aspects of the right to information and its link with the right to freedom of expression, as well as the new challenges that these rights face in the digital age, to then analyze the right to information, its regulation in the Spa…

:CIENCIAS JURÍDICAS [UNESCO]the right to information and the right to informationbeing peacefully settledto then analyze the right to informationshould be reformulated in light of the repeated crisis of transparency. For this2070-8157 22082 Revista Boliviana de Derecho 584568 2021 32 8055240 Derecho de acceso a la información el desafío de una sociedad guiada por la transparencia en el ordenamiento jurídico español Alonso GarcíaTransparencydistancing themselves from a mere summaryexpress mention will be made of transparency from the perspective of political information. Transparencialibertad de expresiónthe most significant aspects of the right to information and its link with the right to freedom of expressionderecho a/de la informaciónUNESCO::CIENCIAS JURÍDICASseek to encourage doctrinal and political debate on assumptions thatbuen gobiernofreedom of expressionright to informationits regulation in the Spanish legal system and the doctrinal debate about its consideration as a fundamental right. As the last point of this contributionas well as the new challenges that these rights face in the digital agegood governance 828 861firstit will be articulated by addressingNieves This study will address the two aspects of rights linked to informationto end with the formulation of some conclusions that
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Application of the Article 28 (3) of the General Data Protection Regulation in contemporary Software as a Service (“SaaS”) business.

2019

For the purposes of this thesis, regulatory requirements associated with the Data Processing Agreement (DPA) are subject to interpretation in the context of SaaS delivery models widely adopted by prominent SaaS providers. In addition, the author argues that, multiple parties processing personal data leads to problems in determining the correct processing role. Thereby, parties may struggle in meeting the requirements of Article 28 (3) of the General Data Protection Regulation (GDPR). Failure to ensure that processing is covered by the proper DPA is regarded as an infringement of the GDPR. For that reason, the thesis seeks to stress out complications associated with structuring DPA’s and pro…

:LAW/JURISPRUDENCE::Other law::European law [Research Subject Categories]General Data Protection Regulation (GDPR)
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Efficacy of an internet-based psychological intervention for problem gambling and gambling disorder: study protocol for a randomized controlled trial

2021

Gambling Disorder is a prevalent non-substance use disorder, which contrasts with the low number of people requesting treatment. Information and Communication Technologies (ICT) could help to enhance the dissemination of evidence-based treatments and considerably reduce the costs. The current study seeks to assess the efficacy of an online psychological intervention for people suffering from gambling problems in Spain. The proposed study will be a two-arm, parallel-group, randomized controlled trial. A total of 134 participants (problem and pathological gamblers) will be randomly allocated to a waiting list control group (N = 67) or an intervention group (N = 67). The intervention program i…

A ActionDGOJ Directorate General for the Regulation of GamblingCIDI Composite International Diagnostic InterviewPA Positive AffectSPIRIT Standard Protocol Items Recommendations for Interventional TrialsefficacyPsychological interventionMotivational interviewingGE Gambling ExpectanciesDSM-IV Diagnostic and Statistical Manual of Mental Disorders Fourth EditionOASIS The Overall Anxiety Severity and Impairment Scalelaw.inventionDERS Difficulties in Emotion Regulation ScaleRandomized controlled triallawPANAS The Positive and Negative Affect SchedulePsychologyRCT Randomized Controlled TrialUPPS-P The Short UPPS-P Impulsivity ScaleICD-10 International Statistical Classification of Diseases and Related Health Problems 10th RevisionCognitionT58.5-58.64GRCS-S Gambling-Related Cognitions ScalePC Predictive ControlBF1-990EDBs Emotion Driven BehavioursC ContemplationGSEQ Gambling Self-Efficacy QuestionnaireDSM-5 Diagnostic and Statistical Manual of Mental Disorders Fifth EditionAnxietyAddicció a Internetmedicine.symptomMI Motivational InterviewingPsychologyJocs per ordinadorM Maintenancemedicine.medical_specialtyemotion regulationG-SAS The Gambling Symptom Assessment ScaleEMA Ecological Momentary AssessmentODSIS The Overall Depression Severity and Impairment ScaleEfficacyWL Waiting ListIC Illusion of ControlIB Interpretative BiasMFS Monitoring Feedback and SupportCBTHealth InformaticsInformation technologyCBT Cognitive Behavioral TherapyImpulsivityCONSORT-EHEALTH Consolidated Standards of Reporting Trials of Electronic and Mobile Health Applications and Online TelehealthISG Perceived Inability to Stop GamblingQuality of life (healthcare)URICA The University of Rhode Island Change Assessment ScaleIntervention (counseling)medicineGD Gambling DisorderSCID-P The Structured Clinical InterviewPsychiatryQLI Quality Life IndexInternetEmotion regulationFull length ArticleSUS System Usability ScalegamblingEMI Ecological Momentary InterventionMINI Mini International Neuropsychiatric InterviewGI Gambling history interview and current gambling situation and related variables assessmentNA Negative AffectGamblingNODS NORC DSM-IV Screen for Gambling ProblemsPFIs Personal Feedback InterventionsDSM-III-R Diagnostic and Statistical Manual of Mental Disorders 3rd Edition RevisedHADS Hospital Anxiety Depression ScaleinternetP Precontemplation
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CLINICAL CHARACTERISTICS AND PLASMA LIPIDS IN SUBJECTS WITH FAMILIAL COMBINED HYPOLIPIDEMIA: A POOLED ANALYSIS

2013

Background. Angiopoietin-like 3 (ANGPTL3) regulates lipoprotein metabolism by modulating extracellular lipases. Loss-of function mutations in ANGPTL3 gene cause familial combined hypolipidemia (FHBL2). The mode of inheritance and hepatic and vascular consequences of FHBL2 have not been fully elucidated. To get further insights on these aspects, we re-evaluated the clinical and the biochemical characteristics of all reported cases of FHBL2. Methods and Results. One hundred fteen FHBL2 individuals carrying 13 different mutations in the ANGPTL3 gene (14 homozygotes, 8 compound heterozygotes and 93 heterozygotes) and 402 controls were considered. Carriers of 2 mutant alleles had undetectable pl…

ANGPTL3 mutations; angiopoietin-like 3; cardiovascular disease; diabetes mellitus; fatty liverSettore MED/09 - Medicina InternaCompound heterozygosityBiochemistryCohort StudiesHypobetalipoproteinemiasEndocrinologyANGPTL3cardiovascular diseaseGenotypeChildLipoproteinclinical characteristicsAged 80 and overbiologydiabetes mellituFatty liverHomozygoteLipoprotein(a)Middle AgedANGPTL3 mutationLipidsCardiovascular Diseasesdiabetes mellitusANGPTL3 Familial combined hypolipidemia LipoproteinAdultmedicine.medical_specialtyHeterozygoteANGPTL3; Familial combined hypolipidemia; clinical characteristicsAdolescentEvinacumabQD415-436Young AdultDiabetes mellitusInternal medicinemedicineHumansANGPTL3 mutationsAlleleFamilial combined hypolipidemiaAgedAngiopoietin-Like Protein 3fatty liverangiopoietin-like 3Cell Biologymedicine.diseaseEndocrinologyAngiopoietin-like ProteinsGene Expression RegulationMutationbiology.proteinPatient-Oriented and Epidemiological ResearchAngiopoietinsLipoproteinLipoprotein(a)
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Genome and phenotype microarray analyses of rhodococcus sp. BCP1 and rhodococcus opacus R7: Genetic determinants and metabolic abilities with environ…

2015

In this paper comparative genome and phenotype microarray analyses of Rhodococcus sp. BCP1 and Rhodococcus opacus R7 were performed. Rhodococcus sp. BCP1 was selected for its ability to grow on short-chain n-alkanes and R. opacus R7 was isolated for its ability to grow on naphthalene and on o-xylene. Results of genome comparison, includ- ing BCP1, R7, along with other Rhodococcus reference strains, showed that at least 30% of the genome of each strain presented unique sequences and only 50% of the predicted proteome was shared. To associate genomic features with metabolic capabilities of BCP1 and R7 strains, hundreds of different growth conditions were tested through Phenotype Microarray, b…

AROMATIC-COMPOUNDS; GENUS RHODOCOCCUS; HIGH-THROUGHPUT; PATHWAY; DEGRADATION; BIODEGRADATION; EQUI; PERFORMANCE; CATABOLISMGenomics RhodococcusGene predictionBacterial Proteinlcsh:MedicineBiologyGenomeXenobioticsRhodococcus opacusBacterial ProteinsRhodococcuslcsh:ScienceGenePhylogenyGeneticsComparative genomicsMultidisciplinarylcsh:RMetabolic Networks and PathwayPhenotype microarrayHigh-Throughput Nucleotide SequencingRhodococcus sp. BCP1 Rhodococcus opacus R7Genome analysisGene Expression Regulation BacterialGenomicsSequence Analysis DNAbiology.organism_classificationBIO/19 - MICROBIOLOGIA GENERALEBiodegradation EnvironmentalPhenotypeProteomeGenomiclcsh:QPhenotype MicroarrayRhodococcusMetabolic Networks and PathwaysRhodococcuhydrocarbon degradationResearch Article
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Collateral sensitivity of drug-resistant ABCB5- and mutation-activated EGFR overexpressing cells towards resveratrol due to modulation of SIRT1 expre…

2019

Abstract Background In the drug discovery field, natural products deemed a precious source of novel lead compounds. They have the ability to bypass or overcome multidrug resistance (MDR) in cancer cells. Purpose In this study, the natural polyphenolic stilbene resveratrol (RES) has been studied for its cytotoxic activity toward MDR cancer cells. Methods Resazurin assay was used to investigate the cytotoxicity of RES not only against a panel of drug-resistant cancer cells overexpressing P-glycoprotein/ABCB1, BCRP/ABCG2, ABCB5 (ATP-binding cassette transporters), but also mutation-activated EGFR. The assessment of proteins expression was done by Western blot analysis. COMPARE and hierarchical…

ATP Binding Cassette Transporter Subfamily BAbcg2Pharmaceutical ScienceResveratrol03 medical and health scienceschemistry.chemical_compound0302 clinical medicineSirtuin 1Cell Line TumorDrug DiscoveryCytotoxic T cellHumansATP Binding Cassette Transporter Subfamily B Member 1CytotoxicityPromoter Regions GeneticTranscription factor030304 developmental biologyPharmacology0303 health sciencesbiologySirtuin 1ChemistryNF-kappa BAntineoplastic Agents PhytogenicDrug Resistance MultipleMultiple drug resistanceErbB ReceptorsGene Expression Regulation NeoplasticComplementary and alternative medicineDrug Resistance NeoplasmResveratrol030220 oncology & carcinogenesisCancer cellMutationbiology.proteinCancer researchMolecular MedicinePhytomedicine : international journal of phytotherapy and phytopharmacology
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