Search results for " Regulator"
showing 10 items of 728 documents
The Sequential Switching Shunt Maximum Power Regulator and its Application in the Electric Propulsion System of a Spacecraft
2007
This paper describes a baseline solution of a Power Conditioning and Distribution Unit (PCDU) for Electrical Propulsion (EP) systems. The solution adopted uses two high efficiency, low-mass power regulators; a solar array regulator (SAR) based on the classical Sequential Switching Shunt Regulator with Maximum Power Point Tracking (MPPT) capability followed by a step-up converter to achieve the desired regulated bus voltage. This paper focuses on the first part of the PCDU, the Sequential Switching Shunt Maximum Power Regulator (S3MPR). This electrical architecture has been adapted and recently proposed for the Electric Propulsion power system of the European and Japanese Mercury Mission (Be…
Non-linear digital control improving transient response: Design and test on a multiphase VRM
2010
Multiphase interleaved buck converters are widely used for point of load applications, especially for VRMs. Performance optimization issue often clashes with size and cost requirements thus leading the industrial and academic research to focus on advanced solutions. This paper presents a control technique for multiphase VRMs including two interacting sections: the linear loop implements a PWM peak current mode control and the nonlinear subsystem modifies few linear loop parameters under load transients only. Steady-state performances are affected by the linear control only while dynamic performance optimization is a non-linear algorithm issue. The proposed control system improves the dynami…
On the Impact of Plant Model and Controller Sophistication on Performance of Disturbance Attenuation and System Robustness
2006
In the paper the problem of disturbance attenuation performance in single-loop control system is investigated. Modified MV control strategy with bounded control variance is used as benchmark for both LQG and classically and optimally tuned PID-type controllers. Certain time and frequency domain functions are then examined to further assess the control performance in terms of robustness. It has been shown that as long as the system to be controlled is delay-free, and there is no extreme demand on performance, simple lag-delay system model along with optimally tuned PID control algorithm provides control quality similar to that of LQG controlled original system assuming the same bound on cont…
Computer active control of damping fluid of a racing superbike suspension scheme for road safety improvement spin-off
2008
This paper describes in detail a computational investigation of a newly-conceived scheme of hydraulic active racing motorcycle suspension and its design application based on a computer-aided control of damping fluid. Through ad hoc tests on a full-scale model setup and the theoretical approach of a non linear 8th-order suspension scheme, this study gives enhancement of the damping fluid active control on the feedback branch of the entire control system for significant improvement of the suspension response to typical road inputs. Briefly, the fluid flow in suspension dampers - generated through well-suited high-pressure hydraulic circuit - shall be conveniently controlled in direction and m…
A back to back method for the temperature rise test of prefabricated substations: A case study
2015
In this work a back to back method is presented which allows to develop heating tests of prefabricated secondary substations with a limited number of supplying equipment (an induction regulator and a capacitor bank). The proposed method makes use of the transformer tap changers to create a voltage difference on the medium voltage side. In this way, only an adjunctive low voltage supply is needed. With the proposed test system, the heating tests are developed on a 1000 kVA prefabricated substation. Thanks to the experimental tests, the class of enclosure of the substation and the operating temperature and resistance of the power transformers are determined, according to the recommendations o…
Closed-loop bandwidth impact on MVSA for rotor broken bar diagnosis in IRFOC double squirrel cage induction motor drives
2013
This paper investigates the detectability of rotor broken bars in indirect rotor flux oriented control (IRFOC) for variable speed double cage induction motor drives, using vibration signature analysis techniques. The Impact of the closed loop control system cannot be neglected when the detection of rotor asymmetries in the machine is based on the signature analysis of electrical or mechanical variables. Therefore, the investigation of rotor fault components for different bandwidths of closed-loop regulators is necessary to evaluate its relevance in the above listed variables. This paper investigates the impact of the control system on relevance of the fault components computed from axial an…
Network pharmacology of cancer: From understanding of complex interactomes to the design of multi-target specific therapeutics from nature
2015
Despite massive investments in drug research and development, the significant decline in the number of new drugs approved or translated to clinical use raises the question, whether single targeted drug discovery is the right approach. To combat complex systemic diseases that harbour robust biological networks such as cancer, single target intervention is proved to be ineffective. In such cases, network pharmacology approaches are highly useful, because they differ from conventional drug discovery by addressing the ability of drugs to target numerous proteins or networks involved in a disease. Pleiotropic natural products are one of the promising strategies due to their multi-targeting and d…
Extensive molecular analysis of patients bearing CFTR-related disorders.
2012
Cystic fibrosis transmembrane conductance regulator (CFTR)–related disorders (CFTR-RDs) may present with pancreatic sufficiency, normal sweat test results, and better outcome. The detection rate of mutations is lower in CFTR-RD than in classic CF: mutations may be located in genes encoding proteins that interact with CFTR or support channel activity. We tested the whole CFTR coding regions in 99 CFTR-RD patients, looking for gene mutations in solute carrier (SLC) 26A and in epithelial Na channel (ENaC) in 33 patients who had unidentified mutations. CFTR analysis revealed 28 mutations, some of which are rare. Of these mutations, RT-PCR demonstrated that the novel 1525-1delG impairs exon 10 s…
Oligomeric Sensor Kinase DcuS in the Membrane of Escherichia coli and in Proteoliposomes: Chemical Cross-linking and FRET Spectroscopy
2010
The DcuSR (dicarboxylate uptake sensor and regulator) system of Escherichia coli is a typical two-component system consisting of a membranous sensor kinase (DcuS) and a cytoplasmic response regulator (DcuR) (11, 26, 48). DcuS responds to C4-dicarboxylates like fumarate, malate, or succinate (19). In the presence of the C4-dicarboxlates, the expression of the genes of anaerobic fumarate respiration (dcuB, fumB, and frdABCD) and of aerobic C4-dicarboxylate uptake (dctA) is activated. DcuS is a histidine protein kinase composed of two transmembrane helices with an intermittent sensory PAS domain in the periplasm (PASP) that was also termed the PDC domain (for PhoQ/DcuS/DctB/CitA domain or fold…
Gene Regulation and Species-Specific Evolution of Free Flight Odor Tracking in Drosophila
2018
Running title: flight evolution in Drosophila This is an invited contribution to the special issue on Genetics of Adaptation based on a symposium of the same name at the National Centre for Biological Sciences (TIFR, Bangalore, India) in November 2016; International audience; The flying ability of insects has coevolved with the development of organs necessary to take-off from the ground, generate, and modulate lift during flight in complex environments. Flight orientation to the appropriate food source and mating partner depends on the perception and integration of multiple chemical signals. We used a wind tunnel-based assay to investigate the natural and molecular evolution of free flight …