Search results for " Respiratory"

showing 10 items of 3117 documents

Balancing of mitochondrial translation through METTL8-mediated m3C modification of mitochondrial tRNAs.

2021

Mitochondria contain a specific translation machinery for the synthesis of mitochondria-encoded respiratory chain components. Mitochondrial tRNAs (mt-tRNAs) are also generated from the mitochondrial DNA and, similar to their cytoplasmic counterparts, are post-transcriptionally modified. Here, we find that the RNA methyltransferase METTL8 is a mitochondrial protein that facilitates 3-methyl-cytidine (m3C) methylation at position C32 of the mt-tRNASer(UCN) and mt-tRNAThr. METTL8 knockout cells show a reduction in respiratory chain activity, whereas overexpression increases activity. In pancreatic cancer, METTL8 levels are high, which correlates with lower patient survival and an enhanced resp…

0303 health sciencesMitochondrial DNAMitochondrial translationRespiratory chainTranslation (biology)[SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry Molecular Biology/Molecular biologyCell BiologyMethylationMitochondrionBiologyCell biology03 medical and health sciences0302 clinical medicineMitochondrial respiratory chain[SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN]Mitochondrial ribosomeMettl8 ; Rna Modification ; M(3)c ; Mt-trna ; TranslationMolecular Biology030217 neurology & neurosurgeryComputingMilieux_MISCELLANEOUS030304 developmental biology
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Impact of COVID-19 on the self-reported physical activity of people with complete thoracic spinal cord injury full-time manual wheelchair users

2021

Coronavirus SARS-CoV-2; COVID-19; 2019-nCoV; Activitat física; Lesió medul·lar Coronavirus SARS-CoV-2; COVID-19; 2019-nCoV; Actividad física; Lesión de la médula espinal Coronavirus SARS-CoV-2; COVID-19; 2019-nCoV; Physical activity; Spinal cord injury Context The emergence of COVID-19 caused a new public health crisis, leading to major changes in daily life routines, often including physical activity (PA) levels. The main goal of this study was to analyze the differences in self-reported physical activity of people with complete spinal cord injuries between the time prior to the COVID-19 lockdown and the lockdown period itself. Methods A sample of 20 participants with complete thoracic spi…

030506 rehabilitationmedicine.medical_specialty2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Clinical NeurologyPhysical activityManual wheelchair:terapéutica::terapéutica::modalidades de fisioterapia::terapéutica::tratamiento por actividad física [TÉCNICAS Y EQUIPOS ANALÍTICOS DIAGNÓSTICOS Y TERAPÉUTICOS]03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitation:Therapeutics::Therapeutics::Physical Therapy Modalities::Therapeutics::Exercise Therapy [ANALYTICAL DIAGNOSTIC AND THERAPEUTIC TECHNIQUES AND EQUIPMENT]:virosis::infecciones por virus ARN::infecciones por Nidovirales::infecciones por Coronaviridae::infecciones por Coronavirus [ENFERMEDADES]Pandèmia de COVID-19 2020-HumansMedicine:enfermedades del sistema nervioso::enfermedades del sistema nervioso central::enfermedades de la médula espinal::traumatismos de la médula espinal [ENFERMEDADES]ExercisePandemicsSpinal cord injurySpinal Cord Injuriesbusiness.industryPublic healthCOVID-19:Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections [DISEASES]medicine.disease:Nervous System Diseases::Central Nervous System Diseases::Spinal Cord Diseases::Spinal Cord Injuries [DISEASES]WheelchairsCommunicable Disease ControlSelf ReportNeurology (clinical)0305 other medical sciencebusinessMedul·la espinal - Malalties - Exercici terapèutic030217 neurology & neurosurgeryThoracic spinal cord injuryThe Journal of Spinal Cord Medicine
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sj-pdf-1-tai-10.1177_2049936121998562 – Supplemental material for Personal protective equipment use by healthcare workers in intensive care unit duri…

2021

Supplemental material, sj-pdf-1-tai-10.1177_2049936121998562 for Personal protective equipment use by healthcare workers in intensive care unit during the early phase of COVID-19 pandemic in Italy: a secondary analysis of the PPE-SAFE survey by Mariachiara Ippolito, Mahesh Ramanan, Davide Bellina, Giulia Catalisano, Pasquale Iozzo, Andrea Di Guardo, Alessandra Moscarelli, Giacomo Grasselli, Antonino Giarratano, Matteo Bassetti, Alexis Tabah and Andrea Cortegiani in Therapeutic Advances in Infectious Disease

110203 Respiratory Diseases111099 Nursing not elsewhere classifiedFOS: Clinical medicine111799 Public Health and Health Services not elsewhere classifiedFOS: Health sciences111403 Paediatrics111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
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sj-pdf-2-tai-10.1177_2049936121998562 – Supplemental material for Personal protective equipment use by healthcare workers in intensive care unit duri…

2021

Supplemental material, sj-pdf-2-tai-10.1177_2049936121998562 for Personal protective equipment use by healthcare workers in intensive care unit during the early phase of COVID-19 pandemic in Italy: a secondary analysis of the PPE-SAFE survey by Mariachiara Ippolito, Mahesh Ramanan, Davide Bellina, Giulia Catalisano, Pasquale Iozzo, Andrea Di Guardo, Alessandra Moscarelli, Giacomo Grasselli, Antonino Giarratano, Matteo Bassetti, Alexis Tabah and Andrea Cortegiani in Therapeutic Advances in Infectious Disease

110203 Respiratory Diseases111099 Nursing not elsewhere classifiedFOS: Clinical medicine111799 Public Health and Health Services not elsewhere classifiedFOS: Health sciences111403 Paediatrics111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
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Author_response_1 – Supplemental material for Patterns and predictors of low physical activity in patients with stable COPD: a longitudinal study

2020

Supplemental material, Author_response_1 for Patterns and predictors of low physical activity in patients with stable COPD: a longitudinal study by María Piedad Sánchez-Martínez, Roberto Bernabeu-Mora, Jose Antonio García-Vidal, Josep Benítez-Martínez, Silvana Loana de Oliveira-Sousa and Francesc Medina-Mirapeix in Therapeutic Advances in Respiratory Disease

110203 Respiratory DiseasesFOS: Clinical medicine111702 Aged Health CareFOS: Health sciences111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
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Reviewer_2_v.1 – Supplemental material for Patterns and predictors of low physical activity in patients with stable COPD: a longitudinal study

2020

Supplemental material, Reviewer_2_v.1 for Patterns and predictors of low physical activity in patients with stable COPD: a longitudinal study by María Piedad Sánchez-Martínez, Roberto Bernabeu-Mora, Jose Antonio García-Vidal, Josep Benítez-Martínez, Silvana Loana de Oliveira-Sousa and Francesc Medina-Mirapeix in Therapeutic Advances in Respiratory Disease

110203 Respiratory DiseasesFOS: Clinical medicine111702 Aged Health CareFOS: Health sciences111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
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Author_Response_1 – Supplemental material for Satisfaction with chronic obstructive pulmonary disease treatment: results from a multicenter, observat…

2019

Supplemental material, Author_Response_1 for Satisfaction with chronic obstructive pulmonary disease treatment: results from a multicenter, observational study by Marco Contoli, Paola Rogliani, Fabiano Di Marco, Fulvio Braido, Angelo G. Corsico, Christian A. Amici, Roberto Piro, Riccardo Sarzani, Patrizia Lessi, Carla Scognamillo, Nicola Scichilone and Pierachille Santus in Therapeutic Advances in Respiratory Disease

110203 Respiratory DiseasesFOS: Clinical medicine111702 Aged Health CareFOS: Health sciences111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
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Author_Response_1 – Supplemental material for Switching from omalizumab to mepolizumab: real-life experience from Southern Italy

2020

Supplemental material, Author_Response_1 for Switching from omalizumab to mepolizumab: real-life experience from Southern Italy by Giovanna Elisiana Carpagnano, Corrado Pelaia, Maria D’Amato, Nunzio Crimi, Nicola Scichilone, Giulia Scioscia, Onofrio Resta, Cecilia Calabrese, Girolamo Pelaia, Carla Maria Irene Quarato and Maria Pia Foschino Barbaro in Therapeutic Advances in Respiratory Disease

110203 Respiratory DiseasesFOS: Clinical medicine111702 Aged Health CareFOS: Health sciences111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
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Author_Response_3 – Supplemental material for Patterns and predictors of low physical activity in patients with stable COPD: a longitudinal study

2020

Supplemental material, Author_Response_3 for Patterns and predictors of low physical activity in patients with stable COPD: a longitudinal study by María Piedad Sánchez-Martínez, Roberto Bernabeu-Mora, Jose Antonio García-Vidal, Josep Benítez-Martínez, Silvana Loana de Oliveira-Sousa and Francesc Medina-Mirapeix in Therapeutic Advances in Respiratory Disease

110203 Respiratory DiseasesFOS: Clinical medicine111702 Aged Health CareFOS: Health sciences111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
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Reviewer_2_v.1 – Supplemental material for Switching from omalizumab to mepolizumab: real-life experience from Southern Italy

2020

Supplemental material, Reviewer_2_v.1 for Switching from omalizumab to mepolizumab: real-life experience from Southern Italy by Giovanna Elisiana Carpagnano, Corrado Pelaia, Maria D’Amato, Nunzio Crimi, Nicola Scichilone, Giulia Scioscia, Onofrio Resta, Cecilia Calabrese, Girolamo Pelaia, Carla Maria Irene Quarato and Maria Pia Foschino Barbaro in Therapeutic Advances in Respiratory Disease

110203 Respiratory DiseasesFOS: Clinical medicine111702 Aged Health CareFOS: Health sciences111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
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