Search results for " Rh"
showing 10 items of 1715 documents
Control of irregular cardiac rhythm
2018
International audience; The aim of this work is to investigate the chaos control of the one di- mensional map which modelizes the duration of the current cardiac action potential (APD) as a function of the previous one. Using OGY control method, we obtain very satisfactory numerical results to stabilize the irregular heart rhythm into the normal rhythm.
THE REFERENCE SITE COLLABORATIVE NETWORK OF THE EUROPEAN INNOVATION PARTNERSHIP ON ACTIVE AND HEALTHY AGEING
2019
International audience; Seventy four Reference Sites of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) have been recognised by the European Commission in 2016 for their commitment to excellence in investing and scaling up innovative solutions for active and healthy ageing. The Reference Site Collaborative Network (RSCN) brings together the EIP on AHA Reference Sites awarded by the European Commission, and Candidate Reference Sites into a single forum. The overarching goals are to promote cooperation, share and transfer good practice and solutions in the development and scaling up of health and care strategies, policies and service delivery models, while at the…
Rhythmic variations in reaction times and evoked potentials
1995
The present work aimed to assess the existence of a regular ultradian cyclicity underlying the variations in amplitude of the N1-P2 component of acoustic EP during a relatively long recording session and investigate its relationship with behavioral measure as RT to the same stimulus. 128 tones were presented to each subject; 128 RTs and the associated EPs to target stimuli were recorded. N1-P2 amplitude has been measured at a single trial level through Woody adaptive filter modified by Wastell. Results showed that there are ultradian rhythmic variations of N1-P2 and RT, with a periodicity from about 5 to 40 min and these variations have similar patterns in the two measures in most of the su…
Red cell sorbitol concentration in relation to short- and medium-term variation of plasma glucose.
1989
To evaluate the time course of changes in red cell sorbitol (RCS) concentration in relation to variations of plasma glucose levels, RCS was determined in 7 normal subjects during i.v. glucose infusion (IVGTT); in 6 hyperglycemic insulin-dependent diabetic subjects while glycemia was normalized with Biostator GC 115 and in 4 diabetic patients in previously poor metabolic control, in whom normal glycemia was obtained in 8–10 days by intensive insulin therapy. During IVGTT, plasma glucose levels increased with significant differences from baseline at 5, 10, 16, 25, 60, 100 and 160 min and returned to basal levels after 3h; RCS concentration showed small and insignificant increases. During i.v.…
Ultradian rhythms in avoidance behavior of DBA mice
1994
This study investigates ultradian rhythm in avoidance behavior of mice, which may constitute a basic rest activity cycle (BRAC). Reaction times (RTs) of an avoidance response to a visual warning stimulus that preceded an electric shock were measured by the use of a computer-controlled shuttle box. The male naive DBA mice were brought to a criterion of 98% correct responses in numerous training sessions. For each subject, all the temporal sequences of the RTs in the trials following achievement of the criterion were examined with discrete Fourier transform. Periodograms were obtained from three sessions for each of the two animals in the first experiment and from 15 subjects in the second ex…
Is the nonREM–REM sleep cycle reset by forced awakenings from REM sleep?
2002
In selective REM sleep deprivation (SRSD), the occurrence of stage REM is repeatedly interrupted by short awakenings. Typically, the interventions aggregate in clusters resembling the REM episodes in undisturbed sleep. This salient phenomenon can easily be explained if the nonREM–REM sleep process is continued during the periods of forced wakefulness. However, earlier studies have alternatively suggested that awakenings from sleep might rather discontinue and reset the ultradian process. Theoretically, the two explanations predict a different distribution of REM episode duration. We evaluated 117 SRSD treatment nights recorded from 14 depressive inpatients receiving low dosages of Trimipram…
Application of 1H NMR-based serum metabolomic studies for monitoring female patients with rheumatoid arthritis
2015
AbstractRheumatoid arthritis is a chronic autoimmune-based inflammatory disease that leads to progressive joint degeneration, disability, and an increased risk of cardiovascular complications, which is the main cause of mortality in this population of patients. Although several biomarkers are routinely used in the management of rheumatoid arthritis, there is a high demand for novel biomarkers to further improve the early diagnosis of rheumatoid arthritis, stratification of patients, and the prediction of a better response to a specific therapy.In this study, the metabolomics approach was used to provide relevant biomarkers to improve diagnostic accuracy, define prognosis and predict and mon…
Prolidase deficiency in two dermatological patients in western Sicily
2020
Prolidase deficiency is a rare disorder inherited through an autosomal recessive gene. The hallmark of the disorder are iminodipeptiduria, chronic skin ulcers, recurring infections, mental retardation and characteristic facial appearance, although prolidase deficiency can occur with no clinical manifestation. The primary biological function of the enzyme involves the metabolism of collagen degradation products and the recycling of proline for collagen resynthesis. We describe two patients with prolidase deficiency and review the different clinical manifestations suggesting the pathogenetic mechanism through few hypotheses.
Safety of anti-tumor necrosis factor-alpha therapy in patients with rheumatoid arthritis and chronic hepatitis C virus infection.
2008
The prevalence of concurrent rheumatoid arthritis (RA) and hepatitis C virus (HCV) infection is probably underestimated because of the increasing spread of this virus worldwide, especially in developing countries. In these patients, anti-tumor necrosis factor-alpha (anti-TNF-alpha) therapy may aggravate hepatitis and increase viremia. We evaluated the safety of these treatments, which remain controversial.Thirty-one HCV-positive patients (23 women, 8 men, mean age 59+/-13 yrs, mean disease duration 13+/-11.5 SD yrs) with active RA [Disease Activity Score 28 (DAS28)3.2] unresponsive to conventional therapies were treated with TNF-alpha blockers (infliximab 11, etanercept 17, adalimumab 3) at…
[Prevalence of pericardial effusion in subjects with rheumatoid arthritis: an echocardiographic study].
1994
We used echocardiography to determine the prevalence of pericardial effusion in rheumatoid arthritis (RA) patients without cardiac systems and compared our results to those obtained in a control group of age-matched subjects. Thirty-six patients with RA (6 men, 30 women; mean age 51 +/- 11 years) were selected from a patient population in treatment at our outpatient Rheumatology Clinic. None of the patients had any symptoms of cardiac disease, and all patients with signs and/or systems of extracardiac disease were excluded from the study. The control group consisted of 60 volunteers (mean age 51 +/- 12 years) randomly selected from a larger group of subjects with neither symptoms, signs and…