Search results for " Right"
showing 10 items of 1166 documents
Deleting Full Length Titin Versus the Titin M-Band Region Leads to Differential Mechanosignaling and Cardiac Phenotypes
2019
Background: Titin is a giant elastic protein that spans the half-sarcomere from Z-disk to M-band. It acts as a molecular spring and mechanosensor and has been linked to striated muscle disease. The pathways that govern titin-dependent cardiac growth and contribute to disease are diverse and difficult to dissect. Methods: To study titin deficiency versus dysfunction, the authors generated and compared striated muscle specific knockouts (KOs) with progressive postnatal loss of the complete titin protein by removing exon 2 (E2-KO) or an M-band truncation that eliminates proper sarcomeric integration, but retains all other functional domains (M-band exon 1/2 [M1/2]-KO). The authors evaluated c…
Rare cardiomyopathies: Diagnostic features
2013
Cardiomyopathies (CM) are an important and heterogeneous group of diseases affecting the myocardium. They can induce mechanical and/or electrical disorders and are due to a variety of causes, they frequently are genetic. However, since their high number and their clinical complexity, the identification is still a challenge. Echocardiography is a very useful tool in the assessment of CM. In this review we aim to define the typical clinical features and to discuss the main diagnostic tool, above all echocardiography that can help physicians in the correct assessment of CM.
Protection of Social Rights as a Permament Challenge for the European Union
2021
Social rights protection in the European Union has undergone significant development. Currently their protection is regulated by relevant treaty provisions and the Charter of Fundamental Rights (Charter), both of a primary law nature, as well as by the non-binding European Pillar of Social Rights (Pillar). The aim of the paper is the assessment of the social rights protection in the EU, and whether all social rights provided in the CFR have their counterparts in the EPSR, hence whether and in what way the EPSR assists the actual exercise of social rights provided by the CFR. Comparing the content of the above-mentioned legal instruments makes it possible to answer the question whether all s…
Diritti dei bambini, diritti delle famiglie. Promuovere e formare le “capacità” genitoriali
2020
The paper focuses on the reasons for the link between children's rights and family rights, in order to highlight that parenting educational competences are challenging risk factor in contexts of poverty and always decisive factor for the actual promotion of the rights of children and adolescents. More precisely, firstly the passages of of the Convention in which the necessity of the family is argued as primary context of children's rights. Secondly, it will be problematized the very idea of children's rights in the light of the "capability approach". On this basis, it will be asked whether, from a pedagogical point of view, the family can, as a whole, be the holder of a right to education…
Children’s rights system in the Republic of Latvia in compliance with international law regarding out-of-family care system
2020
Children rights have been defined in international and domestic legal systems. Despite the ongoing development of children’s rights, it is still a relatively new legal subset of human rights. So far, under the United Nation Convention on the Rights of the Child, there has been the establishment of international and regional legal acts concerning the rights of the child. As a party to different international and regional legal acts, the Republic of Latvia has to undertake obligations to respect and ensure children’s rights in its jurisdiction. However, the necessity to examine international law before domestic legal acts of the Republic of Latvia is to allege full comprehension of a sense of…
Diritti per l’educazione. Contesti e orientamenti pedagogici
2020
The book focuses on the Convention on the Right of child as the result of a slow historical, cultural and in particular pedagogical path of progressive discovery of the specific dignity of childhood and adolescence. It is argue that, even if nowadays, more than thirty years after the drafting of the Convention, the attention to the intrinsic dignity of boys and girls, may seem indisputable and obvious, however such an attention is an achievement for a small part of the world and, also woth regard to the so-called advanced society, one might wonder to what extent and in what contexts, the twentieth century was the century of children and what is really, in the century we are living, the care…
Strenuous endurance exercise and right ventricular systolic function: no evidence of long-term sequelae.
2014
a Faculty of Medicine, Department of Physiology, University of Valencia, Valencia, Spain b Fundacion de Investigacion del Hospital Clinico Universitario Valencia (FIHCUV-INCLIVA), Valencia, Spain c Faculty of Health and Sport Science, University of Zaragoza, Huesca, Spain d Hospital Universitario 12 de Octubre, Research Institute (i + 12), Madrid, Spain e HospitalUniversitario Miguel Servet, Zaragoza, Spain f Cardiology Service, Hospital Universitario Miguel Servet, Zaragoza, Spain g European University of Madrid, Madrid, Spain h Faculty of Medicine, Physical Education and Sports Section, University of Zaragoza, Zaragoza, Spain
El derecho de autonomia del paciente menor: Virtualidad de la mediacion en conflictos sanitarios con menores
2017
La Ley 41/2002, de 14 de noviembre reconoce el derecho a la autonomía del paciente en el ámbito sanitario, configurado como un derecho subjetivo en el marco de los derechos de la personalidad. Recientemente, las Leyes Orgánica 8/2015, de 22 de julio y Ley 26/2015 de 28 de julio han introducido importantes reformas en la consideración de la madurez de los menores para decidir determinados actuaciones que afectan a su persona, confiriendo a sus progenitores la facultad de consentir intervenciones sanitarias que puedan suponer grave riesgo para su vida o salud. Regulación ésta que plantea ciertos interrogantes a la hora de ofrecer soluciones a ciertos conflictos familiares y sanitarios que se …
Margaret A. Simons, Rebel at Heart
2021
Abstract In this interview, Margaret A. Simons describes her path to philosophy and existentialism, her struggles in the male-dominated field in the 1960s and 1970s, and her political activism in the civil rights and women’s liberation movements. She also discusses her encounters with Simone de Beauvoir and Beauvoir’s refusal to own her philosophical originality, suggesting that Beauvoir may have adopted a more conventional narrative of a female intellectual to circumvent the public’s resistance to her radical ideas in the 1950s.
Law, Borders, and Speech Conference: Proceedings and Materials
2017
Tensions between national law and the Internet’s global architecture have existed since the network’s earliest days. They took on new urgency in recent years, with developments like French regulators’ efforts to globally enforce “Right to Be Forgotten” laws. New cases, technologies, and platform responses seem to come along every few months. Expert-level discussion of these issues is dynamic and fast-moving -- but the written literature is only starting to catch up. This volume contributes to that literature by capturing insights from the Stanford Center for Internet and Society’s Law, Borders, and Speech conference. The event honored the twentieth anniversary of David G. Post and David R. …