Search results for " Ring"

Synthesis and biological evaluation of a D-ring-contracted analogue of lamellarin D

2017

A D-ring contracted analogue of the strongly cytotoxic marine pyrrole alkaloid lamellarin D was synthesized and investigated for its antiproliferative action towards a wild type and a multidrug resistant (MDR) cancer cell line. The compound was found to inhibit tumor cell growth at submicromolar concentrations and showed a lower relative resistance in the MDR cell line than the antitumor drug camptothecin to which lamellarin D shows cross resistance and with which lamellarin D shares the same binding site.

The translocation of signaling molecules in dark adapting mammalian rod photoreceptor cells is dependent on the cytoskeleton.

2008

In vertebrate rod photoreceptor cells, arrestin and the visual G-protein transducin move between the inner segment and outer segment in response to changes in light. This stimulus dependent translocation of signalling molecules is assumed to participate in long term light adaptation of photoreceptors. So far the cellular basis for the transport mechanisms underlying these intracellular movements remains largely elusive. Here we investigated the dependency of these movements on actin filaments and the microtubule cytoskeleton of photoreceptor cells. Co-cultures of mouse retina and retinal pigment epithelium were incubated with drugs stabilizing and destabilizing the cytoskeleton. The actin a…

Generalized centro-invertible matrices with applications

2014

Centro-invertible matrices are introduced by R.S. Wikramaratna in 2008. For an involutory matrix R, we define the generalized centro-invertible matrices with respect to R to be those matrices A such that RAR = A^−1. We apply these matrices to a problem in modular arithmetic. Specifically, algorithms for image blurring/deblurring are designed by means of generalized centro-invertible matrices. In addition, if R1 and R2 are n × n involutory matrices, then there is a simple bijection between the set of all centro-invertible matrices with respect to R1 and the set with respect to R2.

Computing with Rational Symmetric Functions and Applications to Invariant Theory and PI-algebras

2012

The research of the first named author was partially supported by INdAM. The research of the second, third, and fourth named authors was partially supported by Grant for Bilateral Scientific Cooperation between Bulgaria and Ukraine. The research of the fifth named author was partially supported by NSF Grant DMS-1016086.

Generation of Certain Matrix Groups by Three Involutions, Two of Which Commute

1997

Ž . We say that a group is 2, 2 = 2 -generated if it can be generated by three involutions, two of which commute. The problem of determining Ž . which finite simple groups are 2, 2 = 2 -generated was posed by Mazurov w x in 1980 in the Kourovka notebook 3 . An answer to this problem, for some classes of finite simple groups, was given by Ya. N. Nuzhin, namely for w x Chevalley groups of rank 1 in 4 , for Chevalley groups over a field of w x characteristic 2 in 5 , and for the alternating groups and Chevalley groups w x of type A in 6 . In this paper we consider the problem in the more n general context of matrix groups over arbitrary, finitely generated, commutative rings. As a special case…

Multiplicative loops of 2-dimensional topological quasifields

2015

We determine the algebraic structure of the multiplicative loops for locally compact $2$-dimensional topological connected quasifields. In particular, our attention turns to multiplicative loops which have either a normal subloop of positive dimension or which contain a $1$-dimensional compact subgroup. In the last section we determine explicitly the quasifields which coordinatize locally compact translation planes of dimension $4$ admitting an at least $7$-dimensional Lie group as collineation group.

On the automorphism group of the integral group ring of Sk wr Sn

1992

Abstract Let G = SkwrSn be the wreath product of two symmetric groups Sk and Sn. We prove that every normalized automorphism θ of the integral group ring Z G can be written in the form θ = γ ° τu, where γ is an automorphism of G and τu denotes the inner automorphism induced by a unit u in Q G.

Automorphisms of the integral group ring of the hyperoctahedral group

1990

The purpose of this paper is to verify a conjecture of Zassenhaus [3] for hyperoctahedral groups by proving that every normalized automorphism () of ZG can be written in the form () = Tu 0 I where I is an automorphism of ZG obtained by extending an automorphism of G linearly to ZG and u is a unit of (JJG. A similar result was proved for symmetric groups by Peterson in [2]; the reader should consult [3] or the survey [4] for other results of this kind. 1989

Automorphisms of the integral group rings of some wreath products

1991

Central Units, Class Sums and Characters of the Symmetric Group

2010

In the search for central units of a group algebra, we look at the class sums of the group algebra of the symmetric group S n in characteristic zero, and we show that they are units in very special instances.