Search results for " SERVER"
showing 10 items of 90 documents
Protein knot server: detection of knots in protein structures
2007
KNOTS (http://knots.mit.edu) is a web server that detects knots in protein structures. Several protein structures have been reported to contain intricate knots. The physiological role of knots and their effect on folding and evolution is an area of active research. The user submits a PDB id or uploads a 3D protein structure in PDB or mmCIF format. The current implementation of the server uses the Alexander polynomial to detect knots. The results of the analysis that are presented to the user are the location of the knot in the structure, the type of the knot and an interactive visualization of the knot. The results can also be downloaded and viewed offline. The server also maintains a regul…
The effect of time and place dependence when utilizing video lectures
2009
In many learning institutes, diversification of teaching with the help of various technologies has become an essential part of educational arrangements. With the increase in the use of networks for teaching purposes, the use of streaming videos is now one of the possibilities to be reckoned with in trying to increase flexibility in studies. Specially recorded on-demand videos provide the students with better chances to decide when, where and how to study. Information on how students use on-demand videos can be obtained, apart from student questionnaires, from the log files of a media server. These files offer an information source that, on the one hand, is diverse but, on the other, cumbers…
A secret sharing scheme for anonymous DNS queries
2013
Since its adoption in the early 90's, several privacy concerns have emerged about the Domain Name System (DNS). By collecting the DNS queries performed by each user, it is possible to characterize habits, interests and other sensitive data of the users. Usually, users resolve their {\em url} requests by querying the DSN server belonging to their Internet Service Provider (ISP) and therefore they assume they can trust it. However, different DNS servers can be used, by revealing sensitive data to a partially untrusted entity that can collect and sell this data for several purposes (target advertising, user profiling, etc.). In this paper we address the possibility to integrate tools in the cu…
Mutational Characterization of the Bile Acid Receptor TGR5 in Primary Sclerosing Cholangitis
2010
Background: TGR5, the G protein-coupled bile acid receptor 1 (GPBAR1), has been linked to inflammatory pathways as well as bile homeostasis, and could therefore be involved in primary sclerosing cholangitis (PSC) a chronic inflammatory bile duct disease. We aimed to extensively investigate TGR5 sequence variation in PSC, as well as functionally characterize detected variants.Methodology/Principal Findings: Complete resequencing of TGR5 was performed in 267 PSC patients and 274 healthy controls. Six nonsynonymous mutations were identified in addition to 16 other novel single-nucleotide polymorphisms. To investigate the impact from the nonsynonymous variants on TGR5, we created a receptor mod…
SQL datubāžu optimizācijas iespējas un salīdzinājums
2015
Datubāzes veiktspēja ir ļoti atkarīga no optimizatora darbības, zināmiem datubāzes defektiem un neprecīzas statistikas. Saturīgas statistikas palīdz strādāt un izvēlēties ātrākos SQL pieprasījumu izpildes plānus. Lai optimizators spētu atbilstoši darboties, tam ir nepieciešamas kvalitatīvas statistikas, bet bieži vien to vākšanas process ir laikietilpīgs un resursus patērējošs. Šajā darbā tiek apskatīti un salīdzināti populārāko datubāžu optimizatoru darbības principi un uzbūve, statistiku vākšanas uzstādījumi un parametri gan teorētiski, gan praktiski. Bakalaura darbs uzskatāms par informatīvu materiālu ar mērķi apkopot informāciju par datubāzēm un optimizācijas iespējām.
Sensitivity Analysis Of Key Customers And Revenue-Oriented Admission Control And Scheduling Algorithm
2013
Received: 15 January 2013 Abstract Accepted: 2 February 2013 The paper deals with the problem of Quality of Web Service (QoWS) in e-commerce Web servers, i.e. in retail Web stores. It concerns the admission control and scheduling algorithm for a Web server system, which aims at preventing the system from overload to provide high QoWS level and ultimately, to increase Web site’s conversion rate, i.e. to turn more visitors into customers. The sensitivity of the algorithm to changes in its basic parameter values was analyzed by using a simulation-based approach. Special attention was paid to evaluation of the parameter impact on conventional and business-related system performance metrics.
Timing and Side Channel Attacks
2015
How would you know the US pentagon is planning an attack on Iraq? One possible plan is to infiltrate the pentagon using spies, flipping traitors etc. But this sounds like lots of work and it is a dangerous work. That is the direct approach. Another possible plan is to ask the pizza delivery guys in the area. People planning an attack probably adds up to lots of people urgently trying to meet deadlines, staying late in the office and ordering pizza. So the pizza delivery guys know about a pending attack! The pizza delivery guys do not know the nature of the attack but they know “something is up” in the pentagon because for a few days people are staying late at the office and ordering pizza a…
Datu noliktavām specifisku īpašību salīdzināšana dažādās izstrādes vidēs
2016
Datu noliktavas pielietošana uzņēmumu vai organizāciju darbā ir efektīvs rīks datu izpētei un secinājumu veikšanai, kas ir nozīmīgi darba efektivitātes uzlabošanai. Taču kāda izstrādes vide labāk nodrošina datu noliktavām nepieciešamo funkcionalitāti? Šajā darbā tiek pētīts, kādas datu noliktavām specifiskas īpašības tiek atbalstītas izstrādes vidēs Microsoft SQL Server, Oracle, PostgreSQL un MySQL. Darbā tiek aplūkots, kādas ir datu noliktavām specifiskas īpašības, kas ir būtiskas datu noliktavas izstrādes vidē, kā arī tiek pētīts, kādas no šīm īpašībām un kādas papildus īpašības tiek atbalstītas katrā no aplūkotajām izstrādes vidēm. Uzdevuma veikšanai tiek pielietota viena datu noliktava,…
Proposal of a neuro-fuzzy model of a WWW server
2005
This paper presents the ways of designing simulation models of Web servers. At the beginning queuing network models are introduced, those models are generally known and often used in the initial phase of research on particular technical solutions. Next, an entirely new approach to the issue discussed is presented - neuro-fuzzy models, thanks to which, it is possible to automate the process of designing simulation models. The results of comparative tests of these two models are presented. Based on these results it can be concluded that neuro-fuzzy models are accurate and can be used in simulation research.
REP2: A Web Server to Detect Common Tandem Repeats in Protein Sequences
2020
Ensembles of tandem repeats (TRs) in protein sequences expand rapidly to form domains well suited for interactions with proteins. For this reason, they are relatively frequent. Some TRs have known structures and therefore it is advantageous to predict their presence in a protein sequence. However, since most TRs diverge quickly, their detection by classical sequence comparison algorithms is not very accurate. Previously, we developed a method and a web server that used curated profiles and thresholds for the detection of 11 common TRs. Here we present a new web server (REP2) that allows the analysis of TRs in both individual and aligned sequences. We provide currently precomputed analyses f…