Search results for " SIT"

showing 10 items of 2985 documents

Bedrock and soil geochemistry influence the content of chemical elements in wild edible mushrooms (Morchella group) from South Italy (Sicily)

2019

Chemical elements in the samples of wild edible mushrooms of the <em>Morchella</em> group collected from different unpolluted Sicilian sites was analyzed by the ICP-MS (method) to detect the content of their minerals and determine whether soil geology and geochemistry can influence the chemical composition in fungi. Results showed that the mushroom samples mainly contained a high concentration of K and P and a wide variety of minor and trace elements (V, Mo, Pb, Ce, Cs, Zr), including heavy metals. Statistical analysis showed that the mushrooms differed in their content of minor and trace elements based on the geological/geographic site of origin. Comparison with other studies s…

mineral contentICP-MS analysisGeochemistryICP-MS analysiBioconcentrationPlant ScienceSettore BIO/01 - Botanica Generalesite geologyGroup (periodic table)Geographic siteChemical compositionlcsh:QH301-705.5Ecology Evolution Behavior and SystematicsMushroomgeographygeography.geographical_feature_categoryBedrockSettore BIO/02 - Botanica SistematicafungiMorchellalanguage.human_languagelcsh:Biology (General)languagefungiaccumulation factorSicilianActa Mycologica
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Modeling the Sustainable Educational Process for Pupils from Vulnerable Groups in Critical Situations: COVID-19 Context in Lithuania, Latvia, and Est…

2022

The critical situation in education caused by COVID-19 has significantly reduced the involvement of pupils from vulnerable groups, particularly those with low learning achievements. The aim of this study is to reveal the modeling of the sustainable educational process and the factors that ensure optimal learning achievements of pupils from vulnerable groups in general education schools in critical educational transformation situations. To reveal the factors ensuring the sustainability of educational processes, this study was conducted in three Baltic countries (Lithuania, Latvia, and Estonia) involving 1432 subject teachers from public education schools. The results of the study highlight t…

modeling of the educational processEnvironmental effects of industries and plantsRenewable Energy Sustainability and the Environmentsustainable achievementsGeography Planning and DevelopmentCOVID-19TJ807-830Management Monitoring Policy and LawTD194-195Renewable energy sourcesEnvironmental sciencessustainable achievements; critical situations; learning difficulties; modeling of the educational process; COVID-19critical situationsGE1-350learning difficultiesSustainability
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Case-specific performance of MM-PBSA, MM-GBSA, and SIE in virtual screening.

2015

In drug discovery the reliable prediction of binding free energies is of crucial importance. Methods that combine molecular mechanics force fields with continuum solvent models have become popular because of their high accuracy and relatively good computational efficiency. In this research we studied the performance of molecular mechanics generalized Born surface area (MM-GBSA), molecular mechanics Poisson-Boltzmann surface area (MM-PBSA), and solvated interaction energy (SIE) both in their virtual screening efficiency and their ability to predict experimentally determined binding affinities for five different protein targets. The protein-ligand complexes were derived with two different app…

molecular mechanics generalized Born surface areaPhosphodiesterase InhibitorsMolecular Dynamics Simulationta3111Molecular mechanicsMolecular Docking Simulationbeta-LactamasesMolecular dynamicssolvated interaction energyBacterial ProteinsComputational chemistryAldehyde ReductaseDrug DiscoveryMaterials ChemistryHumansHSP90 Heat-Shock ProteinsPhysical and Theoretical ChemistryBeta-Lactamase InhibitorsSpectroscopymolecular mechanics Poisson-Boltzmann surface areaMM-GBSAVirtual screeningBinding SitesChemistryPhosphoric Diester Hydrolasesta1182Hydrogen BondingInteraction energyvirtual screeningComputer Graphics and Computer-Aided DesignMolecular Docking SimulationMM-PBSAModels ChemicalROC CurveSolvent modelsDocking (molecular)Area Under CurveBiological systemReceptors Progesteronebeta-Lactamase InhibitorsHydrophobic and Hydrophilic InteractionsProtein BindingJournal of molecular graphicsmodelling
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Il movimento del '77 nella "società dello spettacolo"

2014

movimenti antagonisti situazionismo general intellect postfordismo
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Indijas Republikas un Eiropas Savienības valodas politikas salīdzinājums

2017

Maģistra darba „Indijas Republikas un Eiropas Savienības valodas politikas salīdzinājums” mērķis ir aplūkot Indijas Republikas kā multilingvālas valsts un Eiropas Savienības kā pārnacionāla veidojuma valodu situāciju un salīdzināt abu valstisko veidojumu valodas politikas raksturīgākās iezīmes. Pētījumu papildina izvērsts Indijas Republikas un Eiropas Savienības vēsturiski sociālpolitisks fons, kas valodas politiku un valodu situāciju ļauj vērtēt no dažādiem skatpunktiem, kā arī ilustrē atšķirīgus aspektus (juridiskus, lingvistiskus, vēsturiskus, politiskus, ekonomiskus, sociālus un etnodemogrāfiskus), kuri ietekmē valodas ideoloģiju, praksi un pārvaldību un ir ņemami vērā gan valodas polit…

multilingvismsEiropas Savienībavalodas politikaIndijas RepublikaFiloloģijavalodas situācija
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Osteoprotegerin (OPG) and RANKL expression and distribution in developing human craniomandibular joint.

2005

Abstract During embryogenesis the bone tissue of craniomandibular joint (CMJ) is formed through two pathways: intramembranous ossification and endochondral ossification. The development process is under the control of regulatory factors.The osteoprotegerin (OPG) and the receptor activator of nuclear factor (NF)-κB ligand are key regulators of osteoclastogenesis. The aim of this study is the localization of OPG and RANKL mRNA and protein in the foetal CMJ by immunohistochemistry (IHC) and in situ hybridization (ISH). The main results were: OPG and RANKL mRNA and protein were co-localized in the same cell types; OPG and RANKL were specially immunolocated in osteogenic cells; immunolabeling wa…

musculoskeletal diseasesCartilage Articularmedicine.medical_specialtyReceptors Cytoplasmic and NuclearIn situ hybridizationBiologyBone tissueReceptors Tumor Necrosis FactorBone remodelingOsteoprotegerinOsteogenesisInternal medicineBone cellmedicineHumansRNA MessengerEndochondral ossificationIn Situ HybridizationGlycoproteinsMembrane GlycoproteinsReceptor Activator of Nuclear Factor-kappa BTemporomandibular JointRANK LigandOsteoprotegerinCell BiologyGeneral MedicineImmunohistochemistryCell biologyEndocrinologymedicine.anatomical_structureRANKLIntramembranous ossificationbiology.proteinCarrier ProteinsDevelopmental BiologyTissuecell
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Osteogenic differentiation of periodontal fibroblasts is dependent on the strength of mechanical strain

2012

Abstract Objective During orthodontic therapy the correct strength of mechanical strain plays a key role for bone remodelling during tooth movement. Aim of this study was to investigate the osteogenic differentiation of human periodontal ligament fibroblasts (HPdLF) depending on the applied strength of mechanical strain compared to osteoblasts (HOB). Design HPdLF and HOB were loaded with different strengths (1%, 5% and 10%) of static mechanical strain (SMS) for 12 h in vitro. Viability was verified by MTT and apoptosis by TUNEL assay. Gene expression of cyclin D1, collagen type-1 (COL-I), alkaline phosphatase (ALP), osteocalcin, osteoprotegerin (OPG) and receptor activator of the NF-κB liga…

musculoskeletal diseasesCell SurvivalPeriodontal LigamentGene ExpressionDentistryApoptosisEnzyme-Linked Immunosorbent AssayReal-Time Polymerase Chain ReactionCollagen Type IBone remodelingAndrologyCyclin D1OsteoprotegerinOsteogenesisIn Situ Nick-End LabelingHumansPeriodontal fiberCyclin D1RNA MessengerGeneral DentistryCells CulturedAnalysis of VarianceOsteoblastsTUNEL assaybiologybusiness.industryChemistryRANK LigandOsteoprotegerinCell DifferentiationCell BiologyGeneral MedicineFibroblastsAlkaline PhosphataseOtorhinolaryngologyRANKLOsteocalcinbiology.proteinAlkaline phosphataseStress MechanicalbusinessArchives of Oral Biology
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Influence of Drilling Technique on the Radiographic, Thermographic, and Geomorphometric Effects of Dental Implant Drills and Osteotomy Site Preparati…

2020

The aim of this comparative study is to analyze the influence of drilling technique on the radiographic, thermographic, and geomorphometric effects of dental implant drills and osteotomy site preparations. One hundred and twenty osteotomy site preparations were performed on sixty epoxy resin samples using three unused dental implant drill systems and four drilling techniques performed with a random distribution into the following study groups: Group A: drilling technique performed at 800 rpm with irrigation (n = 30)

musculoskeletal diseasesOsteotomy siteCone beam computed tomographymedicine.medical_treatmentRadiographyeducationlcsh:MedicineOsteotomyArticle03 medical and health sciences0302 clinical medicineotorhinolaryngologic diseasesmedicineheat generationdrill coolingDental implantOrthodonticsDrillbusiness.industrylcsh:RDrilling030206 dentistryGeneral Medicinedental implants drillsequipment and supplieslow drilling speed030220 oncology & carcinogenesisHeat generationbusinessosteotomyJournal of Clinical Medicine
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IAP proteins as targets for drug development in oncology.

2013

The inhibitors of apoptosis (IAPs) constitute a family of proteins involved in the regulation of various cellular processes, including cell death, immune and inflammatory responses, cell proliferation, cell differentiation, and cell motility. There is accumulating evidence supporting IAP-targeting in tumors: IAPs regulate various cellular processes that contribute to tumor development, such as cell death, cell proliferation, and cell migration; their expression is increased in a number of human tumor samples, and IAP overexpression has been correlated with tumor growth, and poor prognosis or low response to treatment; and IAP expression can be rapidly induced in response to chemotherapy or …

musculoskeletal diseasesProgrammed cell deathCell growthbusiness.industryCellular differentiationapoptosisCell migrationReviewBioinformaticsbody regionsInternal ribosome entry siteImmune systemOncologyDrug developmentApoptosisCancer researchMedicinePharmacology (medical)Smac mimeticsbiological phenomena cell phenomena and immunitybusinessantitumor therapyOncoTargets and therapy
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Different sitting positions influence cross country sit skiers performance : Sitting position influence on force generation and cycle characteristics

2018

Cross country sit skiing is a Paralympic discipline in which athletes due to physical impairment ski sitting on a sit-ski. The impairment influences performance directly and also through sitting position. Athletes with a better trunk control usually adopt a sitting position called “kneeing” in which the hip joints are higher than the knee joints. In contrast, athletes with high impact of impairment prefer a sitting position called “knee high” in which the hip joints are lower than the knee joints. Able bodied athletes skiing on the ergometer in these two sitting positions showed different performance. However, to the best of authors’ knowledge, no studies have examined performance, force pr…

musculoskeletal diseasesTrunk controlForce generationmedicine.medical_specialtySittingsitting positionbiomechanics03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationmedicineta315paralympialaisetCross countrybiologyAthletesBiomechanicscross country sit skiing030229 sport sciencesmusculoskeletal systemSitting Positionsbiology.organism_classificationvammaisurheiluParalympic sport; Sitting position; Performance; Cross country sit skiing; BiomechanicsPosition (obstetrics)biomekaniikkaparalympic sportPsychologyhuman activities030217 neurology & neurosurgeryperformance
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