Search results for " STRESS"

Strategie di difesa attivate in risposta a stress, in embrioni di Paracentrotus lividus

2012

Sea urchin embryos are able to activate different defense strategies against stress. This model system allows to investigate numerous phenomena in multipotent cells, which interact among themselves, in their natural position, bypassing the disadvantages of isolated cells, deprived of their normal network. Cadmium (Cd) treatment triggers the accumulation of metal in embryonic cells and the activation of defense systems depending on concentration and exposure time, through the synthesis of heat shock proteins and/or the initiation of apoptosis. Here we show that Paracentrotus lividus embryos exposed to subacute/sublethal concentrations of Cd adopt autophagy as an additional stratagem to safeg…

A possible role of autophagy for the execution of apoptosis in cadmium-exposed sea urchin embryos

2012

The sea urchin embryo is a suitable model system that offers an excellent opportunity to investigate different defence strategies activated in stress conditions. We previously showed that cadmium treatment provokes the accumulation of metal in dose- and time-dependent manner in embryonic cells and the activation of defence systems, such as the synthesis of HSPs and/or the initiation of apoptosis. Analysing autophagy, by neutral red, acridine orange and LC3-detection, we demonstrated that Cd-exposed embryos adopt this process as an additional stratagem to safeguard the developmental program. We observed that embryos treated with subletal Cd concentration activate a massive autophagic respons…

Sea urchin embryo as a model system for studing autophagy induced by cadmium stress

2010

Bank Erosion and Secondary Circulation in a Meandering Laboratory Flume

2014

Abstract This paper reports peculiar results of experimental investigation on the secondary circulation motion of flow along a meander wave. Experiments were conducted in a large amplitude meandering laboratory channel for two values of the width-to-depth ratio. Here attention is focalized on how secondary motion affects the bank shear stress distribution, influencing the stability of the outer bank. The analysis essentially highlights that, especially for small width-to-depth ratio, as the channel curvature increases, besides the classical central-region secondary circulation cell a counter-rotating circulation cell forms in the outer-bank region. Such counter-rotating circulation cell all…

Therapeutic dosages of raloxifene do not modify myeloperoxidase and F2alpha-isoprostane levels in postmenopausal women.

2005

We investigated the effect of a therapeutic dose of raloxifene on the plasma levels of myeloperoxidase and F2alpha-isoprostanes, two markers of oxidative stress recently described as reliable indicators of coronary heart disease. Contrary to changes described in the literature for estrogens (E), raloxifene did not modify the levels of either myeloproxidase or F2alpha-isoprostanes after 3 or 6 months of treatment.

Mothers' parenting stress and adolescents' emotional separation: The role of youngsters' self orientation

2015

The study examined the association among mothers’ parenting stress, adolescents’ emotional separation and self-orientation toward connectedness. Participants were 194 Italian adolescents, aged from 15 to 19 years (mean age = 17.39, SD = 1.18), and their mothers, aged from 33 to 64 years (mean age = 44.35, SD = 5.40). General findings showed that adolescents’ emotional separation may not necessarily be associated with their mothers’ parenting stress, but both of these variables may be related to adolescents’ personal characteristics, which may contribute to define parent-child relationship. Particularly, adolescents’ orientation towards a connected self was associated negatively with emotion…

Relationships between core self-evaluation, leader empowering behavior, and job security among Jordan University Hospital nurses

2021

Nurses are facing real stressors due to patients’ needs and leaders’ demands. The aim of this study is to explore the perceived level of core self-evaluation (CSE), leader empowering behavior (LEB), and job security among Jordan University Hospital nurses in Amman, the capital of Jordan. Furthermore, it investigates the relationship between the selected variables. Differences of gender, educational level, experience, and site of work are also examined with job security. Moreover, it evaluates the contribution of CSE, LEB, gender, educational level, experience, and site of work in predicting job security among Jordan University Hospital nurses. A descriptive cross-sectional design was adopte…

Reliability and validity of the Home Care STAT (Safety Task Assessment Tool).

2013

Abstract Home care workers are a priority population for ergonomic assessment and intervention, but research on caregivers' exposures to hazards is limited. The current project evaluated the reliability and validity of an ergonomic self-assessment tool called Home Care STAT (Safety Task Assessment Tool). Participants (N = 23) completed a background survey followed by 10–14 days of self-monitoring with the STAT. Results showed that the most frequent task was house cleaning, and that participants regularly performed dangerous manual client moving and transferring tasks. Researcher in-home observations of 14 workers (duration ≤2 h) demonstrated that workers' self-assessments were moderately re…

Magnesium homeostasis and aging.

2010

Aging is very often associated with magnesium (Mg) deficit. Total plasma magnesium concentrations are remarkably constant in healthy subjects throughout life, while total body Mg and Mg in the intracellular compartment tend to decrease with age. Dietary Mg deficiencies are common in the elderly population. Other frequent causes of Mg deficits in the elderly include reduced Mg intestinal absorption, reduced Mg bone stores, and excess urinary loss. Secondary Mg deficit in aging may result from different conditions and diseases often observed in the elderly (i.e. insulin resistance and/or type 2 diabetes mellitus) and drugs (i.e. use of hypermagnesuric diuretics). Chronic Mg deficits have been…

Oxidative stress in environmental-induced carcinogenesis.

2009

Reactive oxygen species (ROS) are the more abundant free radicals in nature and have been related with a number of tissue/organ injuries induced by xenobiotics, ischemia, activation of leucocytes, UV exposition, etc. Oxidative stress is caused by an imbalance between ROS production and a biological system's ability to readily detoxify these reactive intermediates or easily repair the resulting damage. Thus, oxidative stress is accepted as a critical pathophysiological mechanism in different frequent human pathologies, including cancer. In fact ROS can cause protein, lipid, and DNA damage, and malignant tumors often show increased levels of DNA base oxidation and mutations. Different lifesty…