Search results for " STRESS"
showing 10 items of 3936 documents
Adaptations to thermal variation in two Mediterranean limpets - cardiac response and haemocyte lysosomal stability
2012
Patella rustica and Patella caerulea are two congeneric limpet species, both occurring along the rocky shores of the Mediterranean but on different tidal heights. P. rustica is dominant in the upper intertidal zone while P. caerulea is more abundant in the lower part of the same zone. Understanding variations in physiological adaptations to thermal stress is vital when investigating intertidal species' distribution. Hence, to investigate the relationship between their physiological thermal tolerance and intertidal zonation, laboratory experiments were designed to test the hypothesis that the lower zoned P. caerulea has reduced upper thermal limits when compared with higher zoned P. rustica,…
Selection of Membrane RNA Aptamers to Amyloid Beta Peptide: Implications for Exosome-Based Antioxidant Strategies
2019
The distribution of amyloid beta peptide 42 (Aβ42) between model exosomal membranes and a buffer solution was measured. The model membranes contained liquid-ordered regions or phosphatidylserine. Results demonstrated that up to ca. 20% of amyloid peptide, generated in the plasma (or intracellular) membrane as a result of proteolytic cleavage of amyloid precursor proteins by β- and γ-secretases, can stay within the membrane milieu. The selection of RNA aptamers that bind to Aβ42 incorporated into phosphatidylserine-containing liposomal membranes was performed using the selection-amplification (SELEX) method. After eight selection cycles, the pool of RNA aptamers was isol…
Effects of liraglutide on plasma ghrelin concentrations and oxidative stress in patients with type 2 diabetes: a 2-month prospective pilot study.
2012
Dark matters : contrasting responses of stream biofilm to browning and loss of riparian shading
2022
Concentrations of terrestrial-derived dissolved organic carbon (DOC) in freshwater ecosystems have increased consistently, causing freshwater browning. The mechanisms behind browning are complex, but in forestry-intensive regions browning is accelerated by land drainage. Forestry actions in streamside riparian forests alter canopy shading, which together with browning is expected to exert a complex and largely unpredictable control over key ecosystem functions. We conducted a stream mesocosm experiment with three levels of browning (ambient vs. moderate vs. high, with 2.7 and 5.5-fold increase, respectively, in absorbance) crossed with two levels of riparian shading (70% light reduction vs.…
Luokanopettajien kokemuksia työperäisestä stressistä ja työyhteisön tuesta
2017
Tämän tutkimuksen tavoite oli selvittää millaisia subjektiivisia kokemuksia luokanopettajilla on työperäistä stressiä ja miten he kokevat työyhteisön tukevan stressaantunutta opettajaa. Tutkimuksen teoriataustana olivat erilaiset työstressiteoriat sekä sosiaalinen tuki ja sen merkitys työhyvinvointiin opettajan työssä. Tutkimuksemme oli kvalitatiivinen ja keräsimme aineiston teemahaastatteluilla, johon osallistui yhdeksän luokanopettajaa. Haastattelut toteutettiin syksyn 2016 aikana ja haastateltavat valikoituivat harkinnanvaraisella, kriteereihin perustuvalla otannalla. Analysoimme aineistomme aineistolähtöisellä, mutta kysymysohjautuvalla sisällönanalyysillä, tarkemmin teemoittelulla. Tul…
Luokanopettajien empaattisuus ja sen yhteydet työssä koettuun myötätuntouupumukseen sekä myötätuntotyytyväisyyteen
2011
Tutkimuksessa selvitettiin luokanopettajien itsearvioinneissaan ilmaisemaa empaattisuuden tasoa ja sitä, eroavatko naiset ja miehet toisistaan empatian suhteen. Lisäksi tutkittiin opettajien työssään kokemaa myötätuntouupumusta, joka tässä tutkimuksessa koostuu työuupumuksesta ja sekundaarista traumaattisesta stressistä, sekä myötätuntotyytyväisyyttä. Tutkimuksessa selvitettiin myös empatian yhteyttä näihin ilmiöihin. Taustatekijät (sukupuoli, työssäolovuodet, työmäärä, lomautus) huomioitiin ilmiöiden tarkastelussa. Myötätuntouupumusta ja -tyytyväisyyttä opettajien keskuudessa on aikaisemmin tutkittu hyvin vähän ja kyseessä on nuori tutkimusala myös kansainvälisellä tasolla. Aineisto (N = 1…
Autophagy
2021
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide…
MAGNESIUM IN AGING
2011
Magnesium and aging.
2009
Over the past decades, the clinical relevance and biological significance of magnesium (Mg) have been documented. Deficiency in Mg, aside from having a negative impact on the energy production pathway required by mitochondria to generate ATP, also reduces the threshold antioxidant capacity of the aging organism and its resistance to free-radical damage. Mg also acts as an antioxidant against free radical damage of the mitochondria. Chronic inflammation and oxidative stress have both been identified as pathogenic factors in aging and in several age-related diseases. Chronic Mg deficiency results in excessive production of oxygen-derived free radicals and low grade inflammation. Aging is very…
Analysis of the effects of magnetic field on the induced stress in drilled plates
2013
Abstract A drilled plate of ferromagnetic material suitably coupled by coils of enameled copper wire fed by a DC power supply to 30 V is considered in this paper. It is analyzed with finite element and later experiments are performed to validate the obtained results. After polishing the plate, two strain gauges for measuring the deformation along the x axis and along the z axis are installed. The values of strain are 5 μm/m in z direction and −2 μm/m in x direction. The experimental–numerical comparison shows that the laboratory results are lower than numerical, while signs and orders of magnitude are the same. It is concluded that the results of the FEM analysis can be considered acceptabl…