Search results for " Sam"

Tips and tricks for flow cytometry-based analysis and counting of microparticles

2015

Submicron-sized extra-cellular vesicles generated by budding from the external cell membranes, microparticles (MPs) are important actors in transfusion as well as in other medical specialties. After briefly positioning their role in the characterization of labile blood products, this technically oriented chapter aims to review practical points that need to be considered when trying to use flow cytometry for the analysis, characterization and absolute counting of MP subsets. Subjects of active discussions relative to instrumentation will include the choice of the trigger parameter, possible standardization approaches requiring instrument quality-control, origin and control of non-specific ba…

Distrés psicológico en adolescentes víctimas de cyberbullying || Psychological distress among adolescents victims of cyberbullying

2017

Las tecnologías de la información y la comunicación se han incorporado y extendido rápidamente en nuestra sociedad. Actualmente, los niños y adolescentes acceden en edades cada vez más tempranas a los dispositivos electrónicos. A pesar de las grandes ventajas que tienen las tecnologías de la información y la comunicación, las tecnologías también pueden ser utilizadas de manera inapropiada para intimidar y molestar a los iguales, causando graves daños psicológicos en las víctimas. Desde esta perspectiva, el principal objetivo del presente estudio ha sido comprobar el distrés psicológico en una muestra de adolescentes víctimas de cyberbullying. Para ello se midieron las variables: sintomatolo…

Diagnostic and prognostic value of H-FABP in acute coronary syndrome: Still evidence to bring

2018

Abstract The assessment of chest pain patients presenting to the emergency area (EA) is still a clinical challenge, as the majority of patients are not diagnosed with acute coronary syndrome (ACS). New generation high sensitivity c-Tn (hs-cTn) assays have showed better performances compared to the standard c-Tn. However, hs-Tn still presents some limitations. Hence, novel, early biomarkers are needed in this setting. Among all, heart-type fatty acid binding protein (H-FABP) has been largely investigated. This article reviews the studies evaluating H-FABP performance in diagnosing acute myocardial infarction (AMI) and stratifying chest pain patients by risk. H-FABP optimal performances in AC…

Need for Orthodontic Treatment in Pupils Aged between 12 and 15 in the Valencian Region (Spain)

2021

The World Health Organization recommends carrying out periodic epidemiological studies in order to provide a basis for the evaluation of the state of health of the population at any given time

Air pollution and airport apron workers: A neglected occupational setting in epidemiological research.

2020

Abstract Introduction Airport apron workers are occupationally exposed to jet exhaust and major concern is related to the exposure to ultrafine particles (UFP) from aircrafts. To date, little attention has been given to occupational exposures to aircraft-related UFP, although aircraft engines have high emissions of ultrafine particles, which are orders of magnitude higher than residential exposure. UFP could possibly contribute to the development of cancer, heart disease, mental illness, and respiratory symptoms. In addition to particulate matter, apron workers are exposed to other polluting substances associated with vehicles, aircraft exhaust or direct fuel emissions. Methods We performed…

World Health Organization guidelines for cancer pain: a reappraisal

2005

Pain is a prevalent symptom experienced by at least 30% ofpatients undergoing an oncological treatment for metastaticdisease and by more than 70% of advanced cancer patients[1]. In 1986 the World Health Organization [2] published a setof guidelines for cancer pain management based on the three-step analgesic ladder [2]. The main aim of WHO guidelienswas to legitimize the prescribing of strong opioids, arisingfrom evidence of poor management of cancer pain, due toreluctance of health care professionals, institutions, and gov-ernment to use opioids because of fears of addition, toleranceand illegal abuse.Its application is reported to achieve satisfactory pain reliefin up to 90% of patients w…

2017

Abstract Background Neurofeedback (NF) in children with ADHD has been investigated in a series of studies over the last years. Previous studies did not unanimously support NF as a treatment in ADHD. Most studies did not control for unspecific treatment effects and did not demonstrate that self-regulation took place. The present study examined the efficacy of NF in comparison to electromyographic feedback (EMG) to control for unspecific effects of the treatment, and assessed self-regulation of slow cortical potentials (SCP). Methods A total of 150 children aged 7 - 9 years diagnosed with ADHD (82% male; 43% medicated) were randomized to 25 sessions of feedback of slow cortical potentials (NF…

Untersuchungen zur Aktivit�tskinetik des Isoenzymes CK-MB im Serum nach Myokardinfarkt

1978

We investigated the activity kinetics of CK-total and CK-MB in 83 patients with proven myocardial infarctions. Serial serum samples were taken at intervals of 2--6 h. The activity of isoenzym CK-MB was determined by means of the immunological inhibition method. CK-MB activity was determined in all patients. The mean peak activity of CK-MB was 65 U/l (range: 9-241 U/l). At the time of peak CK-MB activity the mean percentage CK-MB activity was 13.2% (range: 3.4--21.7%). The CK-MB activity reached its peak at 17.4 h (range: 3.0--32.5 h) after the onset of retrosternal pain. This is 1.4 h after peak CK-total activity. The mean disappearance rate constant for CK-MB (n = 31) was found to be 9.3 X…

Oral hygiene practices and dental caries prevalence among 12 and 15 years school children in Ambala, Haryana -A cross-sectional study

2015

Background: Dental caries and gum disease are a major public health problem predominantly affecting children worldwide. Therefore the present study was conducted to assess oral hygiene practices, prevalence of dental caries and periodontal diseases among 12 and 15 years old high school children in public and government schools of Ambala district, Haryana and to provide data for planning and evaluation of oral health care promotion programs. Material and Methods: A cross-sectional descriptive survey of 12 and 15 years old children in government and private schools was conducted in Ambala, Haryana. A sample of 992 school children was selected by a two-stage cluster sampling method. Dental car…

Phenotypic Variability and Disparities in Treatment and Outcomes of Childhood Arthritis Throughout the World: Results from the EPOCA Study

2018

Background: The characteristics and burden of childhood arthritis have never been studied on a worldwide basis. We aimed to investigate prevalence of disease categories, treatment modalities and disease status across different geographic areas. Methods: International paediatric rheumatologists were asked to enrol a consecutive sample of children with juvenile idiopathic arthritis. Each patient underwent retrospective and cross-sectional assessments, including parent-reported outcomes. Level of disease activity and damage were correlated with wealth of the country, expressed as gross domestic product per capita. Findings: Between 2011 and 2016, 9,081 patients were enrolled at 130 centres in …