Search results for " Scanning"

showing 10 items of 988 documents

Immunohistochemical marker for Na+ CP type Vα (C-20) and heterozygous nonsense SCN5A mutation W822X in a sudden cardiac death induced by mild anaphyl…

2009

A sudden death likely due to mild anaphylactic reaction in a young man is described. Autoptic, histologic, immunohistochemical, and laboratory findings were strongly consistent with the diagnosis of a mild anaphylactic reaction. Genetic molecular analysis, performed on formalin-fixed, paraffin-embedded tissues, showed a mutation described as W822X in a family with electrocardiographic pattern typical of Brugada Syndrome. It results in a nonsense mutation generating a truncated form of the channel protein. The mutation is due to a point substitution of a guanine with an adenine residue (G2466A). Immunohistochemistry and laser scanning confocal microscopy on sections from heart formalin-fixed…

MaleChannellopathies; Confocal laser scanning microscopy; Immunohistochemistry; Na+ CP type Vα (C-20); Sodium channel; Sudden cardiac death; W822X; Adult; Anaphylaxis; Brugada Syndrome; Fatal Outcome; Humans; Male; Muscle Proteins; Myocardium; Myocytes Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Peanut Hypersensitivity; Sodium Channels; Death Sudden Cardiac; Mutation Missense; 2734; Medical Laboratory Technology; HistologyMuscle Proteinsmedicine.disease_causeSodium ChannelsSudden cardiac deathNAV1.5 Voltage-Gated Sodium ChannelNa+ CP type V[alpha] (C-20)Fatal OutcomeMissense mutationMyocytes CardiacConfocal laser scanning microscopyCP type Vα (C-20)Cellular localizationBrugada syndromeBrugada SyndromeMutationChemistrySodium channelChannellopathiesImmunohistochemistryChannellopathies; Confocal laser scanning microscopy; Immunohistochemistry; Na; +; CP type Vα (C-20); Sodium channel; Sudden cardiac death; W822XDeathMedical Laboratory TechnologyCardiologyCardiacAdultmedicine.medical_specialtyHistologyNa+ CP type V[alpha] (C-20) confocal laser scanning microscopy immunohistochemistry sodium channel channellopathies W822X sudden cardiac deathNonsense mutation2734Mutation MissenseSocio-culturaleNa+ CP type Vα (C-20)+Sudden deathPathology and Forensic MedicineInternal medicinemedicineHumansPeanut HypersensitivityNacardiovascular diseasesW822XAnaphylaxisMyocytesSodium channelMyocardiummedicine.diseaseMolecular biologySuddenSudden cardiac deathDeath Sudden CardiacMutationMissenseNa+ CP type V[alpha] (C-20); confocal laser scanning microscopy; immunohistochemistry; sodium channel; channellopathies; W822X; sudden cardiac death
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Prognostic and therapeutic implications of dipyridamole stress cardiovascular magnetic resonance on the basis of the ischaemic cascade

2008

To determine the prognostic and therapeutic implications of stress perfusion cardiovascular magnetic resonance (CMR) on the basis of the ischaemic cascade.Single centre study in a teaching hospital in Spain.Dipyridamole stress CMR was performed on 601 patients with ischaemic chest pain and known or suspected coronary artery disease. On the basis of the ischaemic cascade, patients were categorised in C1 (no evidence of ischaemia, n = 354), C2 (isolated perfusion deficit at stress first-pass perfusion imaging, n = 181) and C3 (simultaneous perfusion deficit and inducible wall motion abnormalities, n = 66). CMR-related revascularisation (n = 102, 17%) was defined as the procedure prompted by t…

MaleChest Painmedicine.medical_specialtyPerfusion ImagingVasodilator AgentsPerfusion scanningCoronary Artery DiseaseChest painMagnetic resonance angiographyCoronary artery diseaseInternal medicineMyocardial RevascularizationmedicineHumanscardiovascular diseasesmedicine.diagnostic_testbusiness.industryUnstable anginaDipyridamoleMiddle AgedPrognosismedicine.diseaseDipyridamoleExercise TestCardiologyFemalemedicine.symptomCardiology and Cardiovascular MedicinebusinessPerfusionMagnetic Resonance AngiographyMacemedicine.drugHeart
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Fibrinogen Naples I (Bβ A68T) Nonsubstrate Thrombin-Binding Capacities

2001

Fibrinogen Naples I (Bbeta A68T) is characterized by defective thrombin binding and fibrinopeptide cleavage at the fibrinogen substrate site in the E domain. We evaluated the fibrinogen of three homozygotic members of this kindred (II.1, II.2, II.3) who have displayed thrombophilic phenotypes and two heterozygotic subjects (I.1, I.2) who were asymptomatic. Electron microscopy of Naples I fibrin networks showed relatively wide fiber bundles, probably due to slowed fibrin assembly secondary to delayed fibrinopeptide release. We evaluated 125I-thrombin binding to the fibrin from subjects I.1, I.2, II.1, and II.2 by Scatchard analysis with emphasis on the high-affinity site in the D domain of f…

MaleCleavage (embryo)FibrinogenFibrinEpitopeRadioligand AssayThrombinmedicineHumansFibrinopeptideBinding siteFamily Healthchemistry.chemical_classificationFibrinBinding SitesbiologyFibrinogens AbnormalThrombinSequence Analysis DNAHematologyMolecular biologyEnzymeBiochemistrychemistryMicroscopy Electron Scanningbiology.proteinFemaleProtein Bindingmedicine.drugThrombosis Research
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Tetraphyllidean plerocercoids from Western Mediterranean cetaceans and other marine mammals around the world: a comprehensive morphological analysis.

2005

Tetraphyllidean plerocercoids have occasionally been reported in marine mammals, but they have rarely been described in detail, and the ecological significance of these infections is unclear. We described plerocercoids collected from the mucosa of the terminal colon and rectum, the anal crypts, and the hepatopancreatic ducts of 7 striped dolphins Stenella coeruleoalba, 1 Cuvier's beaked whale Ziphius cavirostris, and 3 Risso's dolphins Grampus griseus from the Spanish Mediterranean. We also examined undescribed plerocercoids from 3 cetacean species from the Atlantic and the Pacific. All plerocercoids had a lanceolate body, and a scolex with an apical sucker and 4 sessile monolocular bothrid…

MaleColonDolphinsCetaceaAnal CanalHepatic Duct CommonStenella coeruleoalbaBeaked whalebiology.animalparasitic diseasesSuckerParasite hostingAnimalsGrampus griseusEcology Evolution Behavior and SystematicsbiologyRectumWhalesAnatomybiology.organism_classificationCestode InfectionsZiphius cavirostrisMorphological analysisMicroscopy Electron ScanningCestodaParasitologyFemaleBile DuctsThe Journal of parasitology
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Morphological and molecular characterization of tetraphyllidean merocercoids (Platyhelminthes: Cestoda) of striped dolphins (Stenella coeruleoalba) f…

2005

Two types of tetraphyllidean merocercoids, Phyllobothrium delphini and Monorygma grimaldii, are well known from most cetaceans world-wide. The role of cetaceans in the life-cycle of these merocercoids is unclear because their specific identity is as yet unknown. The problem is compounded by poor descriptions of both merocercoids. We used light and scanning electron microscopy, and histological techniques to provide a thorough description of merocercoids collected from 11 striped dolphins, Stenella coeruleoalba, from the Spanish Mediterranean. We also described, for the first time, specimens of P. delphini with immature proglottides. Our merocercoids were morphologically similar to those des…

MaleDolphinsCestodaCetaceaZoologyHelminth geneticsStenella coeruleoalbaPolymerase Chain ReactionPhylogeneticsbiology.animalMediterranean SeaParasite hostingAnimalsCladePhylogenybiologyBase SequenceAbdominal CavityDNA Helminthbiology.organism_classificationTetraphyllideaInfectious DiseasesRNA RibosomalSpainMicroscopy Electron ScanningCestodaAnimal Science and ZoologyParasitologyFemaleParasitology
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The ependyma on the pineal of the guinea pig (Cavia cobaya)

1978

The proximal part of the epiphysis cerebri of the guinea pig is in close contact with the cerebrosopinal fluid of the third ventricle. A direct contact is not present as the pineal tissue is covered by a continuous ependymal layer. Two types of ependymal cells with different surface protrusions are discussed as being involved in possible interactions between the neuroendocrine tissue of the pineal organ and the cerebrospinal fluid. In addition, two different types of supraependymal structures are found on the ependymal surface of the habenulae and the wall of the third ventricle. Because of their morphological characteristics, these supraependymal structures are thought to be neural element…

MaleEmbryologyPathologymedicine.medical_specialtyEpendymal CellGuinea PigsBiologyPineal GlandCerebral VentriclesGuinea pigCerebrospinal fluidEpendymamedicineAnimalsClose contactThird ventricleEpiphysis cerebriCell BiologyAnatomymedicine.anatomical_structureMicroscopy Electron ScanningFemaleAnatomyEpendymaCavia cobayaDevelopmental BiologyAnatomy and Embryology
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The role of configural information in facial emotion recognition in schizophrenia

2005

International audience; The schizophrenia deficit in facial emotion recognition could be accounted for by a deficit in processing the configural information of the face. The present experiment was designed to further test this hypothesis by studying the face-inversion effect in a facial emotion recognition task. The ability of 26 schizophrenic patients and 26 control participants to recognize facial emotions on upright and upside-down faces was assessed. Participants were told to state whether faces expressed one of six possible emotions (happiness, anger, disgust, fear, sadness, neutrality) in two sessions, one with upright faces and the other with upside-down faces. Discriminability and t…

MaleEmotions[SHS.PSY]Humanities and Social Sciences/PsychologyFACESNeuropsychological TestsAngerBehavioral NeuroscienceDiscrimination Psychological0302 clinical medicineComputingMilieux_MISCELLANEOUSmedia_commonVISUAL SCANNING BEHAVIORAFFECTIVE-DISORDERSSCANPATHSFacial ExpressionSadnessPattern Recognition VisualSchizophrenia[SCCO.PSYC]Cognitive science/PsychologyFemaleSchizophrenic Psychology[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]JUDGMENTOBJECTSPsychologyCognitive psychologyAdultEXPRESSIONPsychosisCognitive Neurosciencemedia_common.quotation_subjectExperimental and Cognitive PsychologyStatistics Nonparametric[ SHS.PSY ] Humanities and Social Sciences/Psychology03 medical and health sciencesPerceptionmedicineHumansPERCEPTIONFacial expressionMemoriaRecognition Psychologymedicine.diseaseDisgust030227 psychiatryDEFICIT[ SDV.NEU ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]SchizophreniaIDENTITYPhotic Stimulation030217 neurology & neurosurgeryNeuropsychologia
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Evaluation of the tissue reaction to a new bilayered collagen matrix in vivo and its translation to the clinic.

2011

This study evaluates a new collagen matrix that is designed with a bilayered structure in order to promote guided tissue regeneration and integration within the host tissue. This material induced a mild tissue reaction when assessed in a murine model and was well integrated within the host tissue, persisting in the implantation bed throughout the in vivo study. A more porous layer was rapidly infiltrated by host mesenchymal cells, while a layer designed to be a barrier allowed cell attachment and host tissue integration, but at the same time remained impermeable to invading cells for the first 30 days of the study. The tissue reaction was favorable, and unlike a typical foreign body respons…

MaleMaterials scienceBiomedical EngineeringConnective tissueNeovascularization PhysiologicBioengineeringContext (language use)Pilot ProjectsMatrix (biology)BiomaterialsMiceMaterials TestingmedicineAnimalsHumansTissue ScaffoldsRegeneration (biology)Foreign-Body ReactionMesenchymal stem cellGranulation tissueSoft tissueBiomaterialCell biologymedicine.anatomical_structureGuided Tissue Regeneration PeriodontalMicroscopy Electron ScanningFemaleCollagenPorosityBiomedical engineeringBiomedical materials (Bristol, England)
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Short-term response of three resin-based materials as desensitizing agents under oral environmental exposure

2012

Objective. This paper focuses on clinical responses after 7 days of oral exposure to two resin-based materials as desensitizing agents compared to a fluoride varnish and on morphological and analytical study as a means to elucidate the mechanism of action. Materials and methods. The elemental composition of Vertise™ Flow (VF), Universal Dentine Sealant (UDS) and Flor-Opal® Varnish (FOV) were investigated by using an X-ray energy dispersive spectrometer (EDX) in conjunction with a scanning electron microscope (SEM). SEM morphology of the material-treated dentine surfaces and pain reduction ability according to the Visual Analogue Scale (VAS) were evaluated in selected hypersensitive teeth. P…

MaleMaterials scienceScanning electron microscopeVisual analogue scaleResin Materials Desensitizing agentsVarnishAdministration OralDentistryChloridechemistry.chemical_compoundSettore MED/28 - Malattie OdontostomatologichemedicineHumansGeneral Dentistrybusiness.industrySealantFluoride varnishSpectrometry X-Ray EmissionEnvironmental ExposureGeneral MedicineEnvironmental exposureResins Syntheticstomatognathic diseaseschemistryvisual_artMicroscopy Electron Scanningvisual_art.visual_art_mediumFemalebusinessFluoridemedicine.drugBiomedical engineering
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Analysis of the tegument of Zygocotyle lunata (Trematoda: Paramphistomidae) adults by scanning electron microscopy.

2012

Paramphistomiasis is a parasitic disease caused by various species of the Paramphistomidae. These species mainly affect domestic and wild ruminants; the economic impact of these diseases is often underestimated. Traditionally, the identification of paramphistomes has been difficult and has been based on morphological aspects such as the body shape, the position of the esophagus and cecae, or the tegumental papillae. Despite the many investigations regarding the tegumental papillae for other paramphistomes, very few efforts have been made using Zygocotyle lunata, partly because many authors differ with respect to the importance of papillae in the classification of paramphistomids. Herein, we…

MaleMice Inbred BALB CbiologyRosette (schizont appearance)SnailsViral tegumentAnatomyRuminantsTrematode InfectionsParamphistomatidaebiology.organism_classificationMicestomatognathic systemMicroscopy Electron ScanningHelminthsAnimalsParasitologyIntegumentParamphistomatidaeTrematodaZygocotyle lunataEcology Evolution Behavior and SystematicsThe Journal of parasitology
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