Search results for " Second"
showing 10 items of 1396 documents
Therapy-Related Myeloid Neoplasms in Patients With Acute Promyelocytic Leukemia Treated With All-Trans-Retinoic Acid and Anthracycline-Based Chemothe…
2010
Purpose We analyzed the incidence, risk factors, and outcome of therapy-related myeloid neoplasms (t-MNs) in patients with acute promyelocytic leukemia (APL) in first complete remission (CR). Patients and Methods From 1996 to 2008, 1,025 patients with APL were enrolled onto three sequential trials (LPA96, LPA99, and LPA2005) of the Programa Español para el Tratamiento de Enfermedades Hematológicas and received induction and consolidation therapy with all-trans-retinoic acid (ATRA) and anthracycline-based chemotherapy. Results Seventeen of 918 patients who achieved CR developed t-MN (10 with < 20% and seven with ≥ 20% of bone marrow blasts) after a median of 43 months from CR. Partial and…
Content variability of bioactive secondary metabolites in Hypericum perforatum L
2021
Abstract St John’s Wort (Hypericum perforatum L.; Hypericaceae) is a perennial medicinal herb widespread and largely used in folk medicine inside the Mediterranean basin. Many bioactive compounds have been identified within its extracts. Under a pharmacological point of view, the most important of them belong to the chemical classes of naphthodianthrones, phloroglucinols and polyphenols. Many factors have been claimed responsible for the phytochemical variability in Hypericum perforatum, such as genotype, geographical origin, harvesting stage and age of the plants. Yet, when harvested plant material is addressed to the industry, the standardization of the active ingredients over cultivation…
Diferències de sexe i edat en la disposició empàtica dels estudiants de secundària
2010
Aquest treball presenta una aproximació a l'estudi de l'empatia i de les variables que influeixen en el seu desenvolupament. L'objectiu principal és determinar en quina mesura influeixen la variable de sexe i la variable d'edat en la disposició empàtica dels adolescents. L'estudi es realitza amb una mostra d'estudiants de secundària (n = 114), homes i dones. Els resultats indiquen que les dues variables analitzades (sexe i edat) tenen un efecte significatiu sobre l'empatia. Les dones es mostren més empàtiques que els homes en totes les dimensions que mesura l'escala IRI. A mesura que avancen en edat, els adolescents mostren una major capacitat per a posar-se en el lloc de l'altre i comprend…
Theodor W. Adorno e il concetto di seconda natura nel Doktor Faustus di Thomas Mann
2018
“Doktor Faustus” of Thomas Mann, as explained by its author, is a novel on German civilization in which music plays the role of paradigm. Nevertheless the author grasps a lot of quotations from different disciplines and topics, ― e.g., theology, policy, philosophy, music, chemistry ― with the aim of depicting the creation of a second nature in music according the rules of twelve-note composition established by Arnold Schoenberg. The starting point of this complicated narrative is the reinterpretation of Theodor W. Adorno’s “Philosophie der neuen Musik”, a book that inspired Mann in tracing the idea of “second nature” created by the composer Adrian Leverkühn. The article focuses on some keyw…
FACILITATING THE ADULT LEARNING PROCESSES IN SECOND CHANCE EDUCATION : WHAT DO THE LATVIAN ADULT LEARNERS AND THEIR EDUCATORS THINK ABOUT ?
2015
The paper aims at presenting the findings of the research on core competences of adult educators conducted in Latvia during the study "Identification and analysis of new challenges and solutions that have influence on engagement and reintegration of adults (18- 24 years) in lifelong learning" funded by ESF project "Support to research in educational field" (sub-activity 1.2.2.3.2.), No 011/0011/1DP/1.2.2.3.2/11/IPIA/VIAA/001. The adult educators and adult learners from the field of second chance education (evening shift schools) were involved in an online survey (2011-2012) using the research tool developed in the project “Qualified to Teach” − QF2TEACH. The main research results are analys…
Risk of second primary cancers in women diagnosed with endometrial cancer in G erman and S wedish cancer registries
2017
Along with the increasing incidence and favorable prognosis, more women diagnosed with endometrial cancer may develop second primary cancers (SPCs). We aimed at investigating risk of SPCs after endometrial cancer in Germany and Sweden to provide insight into prevention strategies for SPCs. Endometrial cancer patients diagnosed at age ≥15 years in Germany during 1997-2011 and in Sweden nationwide during 1997-2012 were selected. Standardized incidence ratios (SIRs), calculated as the ratio of observed to expected numbers of cases, were used to assess the risk of a specific second cancer after endometrial cancer for both German and Swedish datasets. Among 46,929 endometrial cancer survivors in…
25-hydroxy vitamin D levels in healthy premenopausal women: Association with bone turnover markers and bone mineral density
2008
Abstract Background Vitamin D deficiency is very common in elderly people while there are very few reports on its incidence, determinants and metabolic consequences in young subjects. Results In 608 young healthy premenopausal women participating in the BONTURNO study, levels of 25-hydroxyvitamin D [25(OH)D] below 20 ng/ml were found in almost a third of the women. Its levels were inversely ( P 2 ) and directly with sunlight exposure during the summer time, and latitude: i.e. the higher the latitude over Italy, the higher the 25(OH)D level. In women on contraceptive pill the mean 25(OH)D level was significantly increased even when the data were adjusted for age, BMI and sun exposure. 25(OH)…
Preterm birth: incidence, risk factors and second trimester cervical length in a single center population. A two-year retrospective study
2017
To report the incidence and the major risk factors (RFs) associated with preterm birth (PTB), combining both maternal RFs and cervical length (CL), and to understand if cervical length measurement is really useful in all the patients.The study population consisted of 2048 women admitted to the Department of Obstetrics and Gynecology, University Hospital of Messina, over a 2-year period. Preterm cases represented approximately 8.64% of our total population and, exactly, 65% were late preterm, 32% were preterm, and 3% were extremely preterm.An analysis of PTB sub-categories based on gestational age showed a stronger correlation between gestational age and CL among preterm and extremely preter…
The assesment of relationship between the angulation of impacted mandibular third molar teeth and the thickness of lingual bone: A prospective clinic…
2018
Background Our purpose was to investigate the relationship between the angulation of mandibular third molars and the thickness of the lingual bone, which can affect the risk of lingual nerve damage during lower third molars surgical extraction. Material and Methods This study consisted of 104 patients (42 males and 62 females), aged between 18-42 years (24.67 ± 6.11 years). Cone Beam Computed Tomography (CBCT) images were taken for preoperative assessment. The teeth were divided into four groups according to their positions: mesioangular, distoangular, vertical and horizontal. Lingual bone thickness around impacted teeth were measured at three points: cementoenamel junction (CEJ) of the man…
Risk of Second Primary Cancers in Multiple Myeloma Survivors in German and Swedish Cancer Registries
2016
AbstractWe aimed at investigating the distribution and risk of second primary cancers (SPCs) in multiple myeloma (MM) survivors in Germany and Sweden to provide etiological understanding of SPCs and insight into their incidence rates and recording practices. MM patients diagnosed in 1997–2010 at age ≥15 years were selected from the Swedish (nationwide) and 12 German cancer registries. Standardized incidence ratios (SIRs) were used to assess risk of a specific SPC compared to risk of the same first cancer in the corresponding background population. Among 18,735 survivors of first MM in Germany and 7,560 in Sweden, overall 752 and 349 SPCs were recorded, respectively. Significantly elevated S…