Search results for " Severity"
showing 10 items of 284 documents
Inpatient Step Counts, Symptom Severity, and Perceived Health Status After Lung Resection Surgery.
2020
BACKGROUND The clinical relevance of inpatient step counts after lung surgery remains unknown. OBJECTIVE The aim of this study was to identify those factors related to physical activity measured by step count, during the inpatient stay, and its relationship with symptom severity and perceived health status at hospital admission, discharge, and 1 month after discharge. METHODS We studied the inpatient step count of 73 participants who underwent lung resection surgery. The number of steps was measured using a triaxial accelerometer. The health status and the severity of symptoms were examined at hospital admission, discharge, and 1 month after discharge. RESULTS Of the 73 participants, 35 wer…
OARSI/OMERACT Initiative to Define States of Severity and Indication for Joint Replacement in Hip and Knee Osteoarthritis. An OMERACT 10 Special Inte…
2011
Objective.To define pain and physical function cutpoints that would, coupled with structural severity, define a surrogate measure of “need for joint replacement surgery,” for use as an outcome measure for potential structure-modifying interventions for osteoarthritis (OA).Methods.New scores were developed for pain and physical function in knee and hip OA. A cross-sectional international study in 1909 patients was conducted to define data-driven cutpoints corresponding to the orthopedic surgeons’ indication for joint replacement. A post hoc analysis of 8 randomized clinical trials (1379 patients) evaluated the prevalence and validity of cutpoints, among patients with symptomatic hip/knee OA.…
Comparison of two delayed strategies for renal replacement therapy initiation for severe acute kidney injury (AKIKI 2): a multicentre, open-label, ra…
2021
International audience; BACKGROUND: Delaying renal replacement therapy (RRT) for some time in critically ill patients with severe acute kidney injury and no severe complication is safe and allows optimisation of the use of medical devices. Major uncertainty remains concerning the duration for which RRT can be postponed without risk. Our aim was to test the hypothesis that a more-delayed initiation strategy would result in more RRT-free days, compared with a delayed strategy. METHODS: This was an unmasked, multicentre, prospective, open-label, randomised, controlled trial done in 39 intensive care units in France. We monitored critically ill patients with severe acute kidney injury (defined …
Major autohemotherapy as a treatment modality for alveolar osteitis
2018
Purpose.
 Alveolar osteitis is the most common post-odontectomy complication. Although blood clot disintegration is known to be the cause of the condition, an agreement is lacking regarding a treatment of choice. The aim of the current study therefore was to evaluate major autohemotherapy as one treatment method.
 
 Patients and Methods.
 A total of 183 patients were categorized into 4 groups (I, II, III, and IV) according to pain severity (mild, moderate, severe, or agonizing, respectively). Major autohemotherapy was performed for all patients by withdrawing 225mL of patient's blood and mixing them with 225mL of Oxygen-Ozone gas (where Ozone concentration was 50µg/mL ga…
Restoring Neurological Physiology: The Innovative Role of High-Energy MR-Guided Focused Ultrasound (HIMRgFUS). Preliminary Data from a New Method of …
2017
Background Tremor is a disabling condition, common to several neurodegenerative diseases. Lesioning procedures and deep brain stimulation, respectively, of the ventralis intermedius nucleus for intentional tremor, and of the subthalamic nucleus for parkinsonian resting tremor, have been introduced in clinical practice for patients refractory to medical treatment. The combination of high-energy focused ultra-sound (HIFUS) with sophisticated magnetic resonance (MR) instrumentation, together with accurate knowledge of the stereotactic brain coordinates, represents a revolution in neuromodulation. Methods At the Neurosurgical Clinic and the Radiology Department of the University of Palermo,, tw…
Rotavirus gastroenteritis: epidemiological, clinical, therapeutic aspects and economic implications
2013
Results 114 cases were diagnosed with rotavirus gastroenteritis in 2011 and 122 cases in 2012, frequently in the colder months, sex ratio M/F 1.42/1 in 2011, 1.18/1 in 2012 and in the age group 1-3 (58.90% of cases). The clinical severity was assessed by Vesikari score: 91 cases admitted in 2011 (79.82%) and 112 cases admitted in 2012 (91.80%) presenting a medium/severe score. 15 cases presented neurological symptoms and also 15 cases had renal failure. Among the electrolyte disorders the most commonly found was hyponatremia ( 150mEq/L). The hospitalization costs of rotavirus gastroenteritis cases ranged from 58.60€ to 5345 RON (1243.02€).
Consortium for the lifespan examination of ADHD registry (Clear): An update on methodology and recruitment
2011
IntroductionADHD is often unrecognised and untreated, particularly in Europe. There is a need for improved understanding of ADHD in adults and its impact on patients across the lifespan. Registries allow for multiple real-world comparisons based on assessment of patients that are typically excluded from clinical studies. Data describing the cost, burden and consequences of ADHD are essential to inform clinicians, regulatory agencies, payers and patients about the condition.ObjectivesTo address the gaps in our current understanding of the care and cost of treating adult patients with ADHD by documenting real-life experiences.MethodsA prospective, longitudinal, observational study of adults &…
Stress fractures in elite male football players
2010
The objective was to investigate the incidence, type and distribution of stress fractures in professional male football players. Fifty-four football teams, comprising 2379 players, were followed prospectively for 189 team seasons during the years 2001-2009. Team medical staff recorded individual player exposure and time-loss injuries. The first team squads of 24 clubs selected by UEFA as belonging to the 50 best European teams, 15 teams of the Swedish Super League and 15 teams playing their home matches on artificial turf pitches were included. In total, 51 stress fractures occurred during 1,180,000 h of exposure, giving an injury incidence of 0.04 injuries/1000 h. A team of 25 players can …
Clinical characteristics and outcomes of thymoma-associated myasthenia gravis
2021
[Background and purpose] Prognosis of myasthenia gravis (MG) in patients with thymoma is not well established. Moreover, it is not clear whether thymoma recurrence or unresectable lesions entail a worse prognosis of MG.
SARS-CoV-2 RNA load in the lower respiratory tract, viral RNAemia and N-antigenemia in critically ill adult COVID-19 patients: relationship with biom…
2021
ABSTRACTBackgroundLittle is known about the comparative kinetics of SARS-CoV-RNA load in the lower respiratory tract and in blood compartment in patients admitted to the intensive care unit, and how these relate to biomarkers of COVID-19 severity.MethodsSeventy-three consecutive critically ill COVID-19 patients (median age, 65 years) were recruited. Serial lower respiratory tract (n=165) and plasma (n=340) specimens were collected. RT-PCR and lateral flow immunochromatography assay were used for SARS-CoV-2 RNA quantitation and N protein detection in plasma, respectively. Serum levels of inflammatory and tissue-damage biomarkers in paired specimens were analyzed.ResultsSARS-CoV-RNA was detec…