Search results for " Short-Term"
showing 10 items of 173 documents
CSF APPsα and Phosphorylated Tau Protein Levels in Mild Cognitive Impairment and Dementia of Alzheimer's Type
2008
We exploratively measured APPs alpha, a secreted fragment of the non-amyloidogenic cleavage of amyloid precursor protein via a-secretase, and tau protein phosphorylated at threonine 181 (p tau) in the cerebrospinal fluid of 10 patients with mild cognitive impairment, 20 patients with dementia of Alzheimer's type, and 10 controls. Cerebrospinal fluid APPs alpha and p tau levels were correlated with cognitive performance. P tau levels were significantly elevated in mild cognitive impairment and in patients with dementia of Alzheimer's type, APPs alpha levels were significantly reduced in patients with dementia of Alzheimer's type compared to the controls. APPs alpha levels were associated wit…
Working Memory Function in Children with Single Side Deafness Using a Bone-Anchored Hearing Implant: A Case-Control Study
2018
The importance of a good hearing function to preserve memory and cognitive abilities has been shown in the adult population, but studies on the pediatric population are currently lacking. This study aims at evaluating the effects of a bone-anchored hearing implant (BAHI) on speech perception, speech processing, and memory abilities in children with single side deafness (SSD). We enrolled <i>n</i> = 25 children with SSD and assessed them prior to BAHI implantation, and at 1-month and 3-month follow-ups after BAHI implantation using tests of perception in silence and perception in phonemic confusion, dictation in silence and noise, and working memory and short-term memory function…
Reading–writing disorder in children with idiopathic epilepsy
2020
Abstract Several studies have documented learning disabilities (LDs) in subjects with epilepsy, who have been shown to be at greater risk of mild neuropsychological damage, with the consequent risk of academic failure. This retrospective study aimed to investigate the peculiarities of reading and writing disorders in subjects with idiopathic epilepsy. The reading and writing performance of 35 children affected by reading and writing disorders and idiopathic epilepsy (R/WD + E group) has been compared with the performance of 37 children with only reading and writing disorders (R/WD group). A comparison group of 22 typical developing healthy children (TDC group) was also included in the study…
Computer-aided neurocognitive remediation in schizophrenia: durability of rehabilitation outcomes in a follow-up study.
2010
Cognitive deficits in patients with schizophrenia constitute a limiting factor to the chances of rehabilitation of daily living abilities, like personal and relational autonomy and working ability. Cognitive Remediation Therapy (CRT) is a rehabilitative technique that aims at the recovery of single cognitive functions through the execution of massive exercises of impaired cognitive domains. This study aims to establish if the results achieved through an intensive deficit-specific neurocognitive treatment of three months duration, were maintained over time. The sample consists in 100 patients diagnosed with schizophrenia according to the criteria of DSM IV. Patients were assessed on cognitiv…
Improving Children's Coordinative Skills and Executive Functions
2016
Recent studies have focused on the positive influence of regular physical activity on executive functioning in children. Coordinative skills (agility) and executive functions (updating, attention, inhibition and planning processes) were investigated in children before and after 6 months of a Football Exercise Program compared to a control group of sedentary peers. The participants were 44 children aged 8.8 years: Group 1 comprised 24 children in a football (i.e., soccer) exercise program and Group 2 comprised 20 sedentary children. At pre-test and post-test, coordinative skills and executive functions were measured. After the Football Exercise Program, there were significant differences be…
rTMS evidence of different delay and decision processes in a fronto-parietal neuronal network activated during spatial working memory.
2003
The existence of a specific and widely distributed network for spatial working memory (WM) in humans, involving the posterior parietal cortex and the prefrontal cortex, is supported by a number of neuroimaging studies. We used a repetitive transcranial magnetic stimulation (rTMS) approach to investigate the temporal dynamics and the reciprocal interactions of the different areas of the parieto-frontal network in normal subjects performing a spatial WM task, with the aim to compare neural activity of the different areas in the delay and decision phases of the task. Trains of rTMS at 25 Hz were delivered over the posterior parietal cortex (PPC), the premotor cortex (SFG) and the dorsolateral …
When the amnestic mild cognitive impairment disappears: characterisation of the memory profile
2009
BACKGROUND/OBJECTIVES: Subjects affected by mild cognitive impairment (MCI) may improve during the observation period. This is the first study investigating qualitative features of memory deficits in subjects affected by reversible MCI [reversible cognitive impairment (RCI)]. METHODS: Baseline cognitive and memory performances of 18 subjects affected by amnestic MCI who had normalized cognitive performances at follow-ups were compared with those of 76 amnestic MCI subjects who still showed impaired cognitive performances at the 24-month follow-up (MCI) and with those of a group of 87 matched control subjects (normal controls). RESULTS: Compared with normal controls the memory deficit in the…
The contribution of acetylcholine and dopamine to subprocesses of visual working memory--what patients with amnestic mild cognitive impairment and Pa…
2014
Attentional selection, i.e. filtering out of irrelevant sensory input and information storage are two crucial components of working memory (WM). It has been proposed that the two processes are mediated by different neurotransmitters, namely acetylcholine for attentional selection and dopamine for memory storage. However, this hypothesis has been challenged by others, who for example linked a lack in dopamine levels in the brain to filtering deficits. Here we tested the above mentioned hypothesis in two patient cohorts which either served as a proxy for a cholinergic or a dopaminergic deficit. The first group comprised 18 patients with amnestic mild cognitive impairment (aMCI), the second 22…
Effects of recreational scuba diving on Mediterranean fishes: evidence of involuntary feeding?
2013
Despite a large body of literature assessing the impacts of recreational scuba diving on marine habitats, little attention has been paid to the potentially harmful effects this has on fishes. The aim of this study was the assessment of the immediate response of different fish species to divers’ activities. A decrease of fishes’ natural diffidence towards divers is shown, probably due to an enhanced availability of their prey as a result of divers’ contacts with the substrate.
The passive state: A protective mechanism for information in working memory tasks.
2021
Memory representations can be stored in a passive state in a visual working memory (VWM) task. However, it remains unclear whether the representations stored in the passive state are prone to interference and decay. To explore this issue, we asked participants to successively remember two sets of memory items (M1 and M2) in three test manners: a combined test (both M1 and M2 are probed simultaneously), a backward test (probe M2 first and M1 second), or a forward test (probe M1 first and M2 second). We found that the contralateral delay activity (CDA) amplitude after the onset of M2 only tracked M2 independently of M1 in the two separate tests (Experiments 1-3), and the accuracy of M1 was we…