Search results for " Simulation"
showing 10 items of 4034 documents
Links and Bifurcations in Nonsingular Morse–Smale Systems
1997
Wada's theorem classifies the set of periodic orbits in NMS systems on S3 as links, that can be written in terms of six operations. This characterization allows us to study the topological restrictions that links require to suffer a given codimension one bifurcation. Moreover, these results are reproduced in the case of NMS systems with rotational symmetries, introducing new geometrical tools.
New-stage discharge relationships for free and submerged sluice gates
2012
Abstract The flow movement through a sluice gate is investigated for both free and submerged flow conditions. For free flow condition, the current dimensionless formula, indicated acceptable accuracy; while for submerged flow condition it was modified especially for low submerged condition. In this regard, Buckingham theorem along with the Incomplete Self-Similarity concept was employed and a new stage–discharge relationship was developed accordingly. Also, to achieve a suitable formula for submerged flow condition being accurate in low submergence, the maximum tailwater depth allowing the free flow condition and head loss factor were identified as missing parameters in the functional dimen…
New stage-discharge relationship for cylindrical and semi-cylindrical edged sluice gates
2019
Abstract Gates are simple hydraulic structures which have been widely used for flow control and measurement in irrigation networks. In this paper new sluice gates with cylindrical and semi-cylindrical edges were introduced and the flow movement below these types of gates was experimentally investigated for both free- and submerged-flow conditions. The Buckingham theorem of dimensional analysis and the self-similarity theory were applied for developing the stage-discharge relationships for the two investigated flow conditions. For these cylindrical and semi-cylindrical edged gates and a free-flow condition, the proposed stage-discharge relationship was characterized by an estimate error less…
Tackling the Limitations of Copolymeric Small Interfering RNA Delivery Agents by a Combined Experimental–Computational Approach
2019
Despite the first successful applications of nonviral delivery vectors for small interfering RNA in the treatment of illnesses, such as the respiratory syncytial virus infection, the preparation of a clinically suitable, safe, and efficient delivery system still remains a challenge. In this study, we tackle the drawbacks of the existing systems by a combined experimental-computational in-depth investigation of the influence of the polymer architecture over the binding and transfection efficiency. For that purpose, a library of diblock copolymers with a molar mass of 30 kDa and a narrow dispersity (Đ1.12) was synthesized. We studied in detail the impact of an altered block size and/or compos…
ENTROPY SOLUTIONS IN THE STUDY OF ANTIPLANE SHEAR DEFORMATIONS FOR ELASTIC SOLIDS
2000
The concept of entropy solution was recently introduced in the study of Dirichlet problems for elliptic equations and extended for parabolic equations with nonlinear boundary conditions. The aim of this paper is to use the method of entropy solutions in the study of a new problem which arise in the theory of elasticity. More precisely, we consider here the infinitesimal antiplane shear deformation of a cylindrical elastic body subjected to given forces and in a frictional contact with a rigid foundation. The elastic constitutive law is physically nonlinear and the friction is described by a static law. We present a variational formulation of the model and prove the existence and the uniquen…
The Task and Ego Orientation in Sport Questionnaire: Testing for Measurement Invariance and Latent Mean Differences in Spanish and Portuguese Adolesc…
2010
Within the theoretical framework of achievement goals (Nicholls, 1989), Duda and Nicholls (see Duda, 1989; Duda & Whitehead, 1998) developed the Task and Ego Orientation in Sport Questionnaire (TEOSQ) to assess individual differences in achievement goal orientations. This study searches for validity evidence of the TEOSQ in the case of Spanish (2473) and Portuguese (2486) junior high school. The results showed that factor structure, factor loadings, and intercepts could be considered invariant across groups. Between group differences in latent means showed slightly higher mean scores for the Spanish group for both factors. The results also provide high support for the internal consistency o…
Reservoir computing model of prefrontal cortex creates novel combinations of previous navigation sequences from hippocampal place-cell replay with sp…
2019
As rats learn to search for multiple sources of food or water in a complex environment, they generate increasingly efficient trajectories between reward sites. Such spatial navigation capacity involves the replay of hippocampal place-cells during awake states, generating small sequences of spatially related place-cell activity that we call “snippets”. These snippets occur primarily during sharp-wave-ripples (SWRs). Here we focus on the role of such replay events, as the animal is learning a traveling salesperson task (TSP) across multiple trials. We hypothesize that snippet replay generates synthetic data that can substantially expand and restructure the experience available and make learni…
Using random networks to study the dynamics of respiratory syncytial virus (RSV) in the Spanish region of Valencia
2011
[EN] Seasonal fluctuations in the incidence of several respiratory infections are a feature of epidemiological surveys all around the world. This phenomenon is characteristic of influenza and respiratory syncytial virus pandemics. However, the explanation of the seasonal outbreaks of these diseases remains poorly understood. Many statistical studies have been carried out in order to provide a correlation of the outbreaks with climatic or social factors without achieving a definitive conclusion. Here we show that, in a random social network, self-sustained seasonal epidemics emerge as a process modulated by the infection probability and the immunity period after recovering from the infection…
Interindividual Differences in Treatment Effects based on Structural Equation Models with Latent Variables: An EffectLiteR Tutorial
2019
The investigation of interindividual differences in the effects of a treatment is challenging, because many constructs-of-interest in psychological research such as depression or anxiety are latent variables and modeling heterogeneity in treatment effects requires interactions and potentially nonlinear relationships. In this paper, we present a tutorial of the EffectLiteR approach (Mayer, Dietzfelbinger, Rosseel, & Steyer, 2016) that allows for estimating individual treatment effects based on latent variable models. We describe step by step how to apply the approach using the EffectLiteR software package with data from the multicenter randomized controlled trial of the Social Phobia…
Shifting to climate change aware cities to facilitate the city resilience implementation
2020
Abstract Climate change (CC) is one of the most urgent threats to modern societies, having direct and indirect consequences on the rapid growth of urban areas. Cities are attempting to both reduce their impact on the environment and build resilience to be able to face the irreversible effects of CC through plans and strategies. However, barriers, such as the fact that cities are complex systems and the uncertainty posed by CC have led to less engaged and committed city stakeholders, which have hampered the operationalisation of city resilience. In this context, developing city stakeholders awareness has been demonstrated to be an effective way to put an end to passive behaviour and help tra…