Search results for " Simulation"
showing 10 items of 4034 documents
Reverse-engineering post-transcriptional regulation of gap genes in Drosophila melanogaster
2013
16 páginas, 6 figuras, 1 tabla
epiModel: A system to build automatically systems of differential equations of compartmental type-epidemiological models
2011
In this paper we describe epiModel, a code developed in Mathematica that facilitates the building of systems of differential equations corresponding to type-epidemiological linear or quadratic models whose characteristics are defined in text files following an easy syntax. It includes the possibility of obtaining the equations of models involving age and/or sex groups. © 2011.
Historical Buildings in protected areas in Italy: a re-design study of a rural building
2017
Historic and traditional buildings, including rural ones, are a territorial resource in Europe and constitute an integral part of the European’s cultural heritage. However they are often characterized by poor energy performances and a large potential for energy retrofit actions. On the other hand, the hardest part of retrofitting such buildings is the limited invasiveness that such actions need to have on the historical and heritage value of the building itself. The paper describes an experience of re-design of an existing rural building located in Sicily, inside the ancient Greeks “Valley of the Temples”. An energy audit was performed on the building, its energy uses thoroughly investigate…
Novel method and instruments for the optimal techno-economic sizing of borehole heat exchangers
2021
El test de respuesta térmica (TRT) es ampliamente utilizado como método estándar para caracterizar las propiedades térmicas del terreno adyacente a un intercambiador de calor enterrado (BHE). Los métodos tradicionales para interpretar los resultados aplican soluciones analíticas o numéricas asumiendo que el terreno es infinito, homogéneo e isotrópico. Sin embargo, en realidad el subsuelo presenta generalmente una estructura estratificada y heterogénea, y por lo tanto las propiedades térmicas pueden variar sustancialmente con la profundidad. En este sentido y con la intención de resolver las limitaciones del TRT estándar, la presente tesis doctoral se centra en el desarrollo de métodos e ins…
Non-invasive localization of atrial ectopic beats by using simulated body surface P-wave integral maps
2017
Non-invasive localization of continuous atrial ectopic beats remains a cornerstone for the treatment of atrial arrhythmias. The lack of accurate tools to guide electrophysiologists leads to an increase in the recurrence rate of ablation procedures. Existing approaches are based on the analysis of the P-waves main characteristics and the forward body surface potential maps (BSPMs) or on the inverse estimation of the electric activity of the heart from those BSPMs. These methods have not provided an efficient and systematic tool to localize ectopic triggers. In this work, we propose the use of machine learning techniques to spatially cluster and classify ectopic atrial foci into clearly diffe…
In silico pace-mapping: prediction of left vs. right outflow tract origin in idiopathic ventricular arrhythmias with patient-specific electrophysiolo…
2019
Abstract Aims A pre-operative non-invasive identification of the site of origin (SOO) of outflow tract ventricular arrhythmias (OTVAs) is important to properly plan radiofrequency ablation procedures. Although some algorithms based on electrocardiograms (ECGs) have been developed to predict left vs. right ventricular origins, their accuracy is still limited, especially in complex anatomies. The aim of this work is to use patient-specific electrophysiological simulations of the heart to predict the SOO in OTVA patients. Methods and results An in silico pace-mapping procedure was designed and used on 11 heart geometries, generating for each case simulated ECGs from 12 clinically plausible SOO…
Comparison of different assembly and annotation tools on analysis of simulated viral metagenomic communities in the gut
2013
Abstract Background The main limitations in the analysis of viral metagenomes are perhaps the high genetic variability and the lack of information in extant databases. To address these issues, several bioinformatic tools have been specifically designed or adapted for metagenomics by improving read assembly and creating more sensitive methods for homology detection. This study compares the performance of different available assemblers and taxonomic annotation software using simulated viral-metagenomic data. Results We simulated two 454 viral metagenomes using genomes from NCBI's RefSeq database based on the list of actual viruses found in previously published metagenomes. Three different ass…
Pitfalls in the Development of Agent-Based Models in Social Sciences: Avoiding Them and Learning from Them
2019
The references on the principles and methodology for developing agent-based models of social phenomena usually describe general principles and illustrate the process using worked examples, but seldom focus on the pitfalls and errors that make practical model building a tortuous and difficult task. This chapter contains a discussion of the positive and negative aspects of my personal experience in a PhD work on simulation of large scale social conflict. The purpose will be to describe the process from the initial plan to the final dissertation, analyze the pitfalls and their overcoming in terms of principles of model development, and summarize the ideas that I found useful for practical deve…
Novel Concept for Electro-Hydrostatic Actuators for Motion Control of Hydraulic Manipulators
2021
Self-contained hydraulic cylinders have gained popularity in the recent years but have not been implemented for high power articulated hydraulic manipulators. This paper presents a novel concept for an electro-hydrostatic actuator applicable to large hydraulic manipulators. The actuator is designed and analyzed to comply with requirements such as load holding, overload handling, and differential flow compensation. The system is analyzed during four quadrant operation to investigate energy efficiency and regenerative capabilities. Numerical simulation is carried out using path control and 2DOF anti-swing of a hydraulic crane as a load case to illustrate a real world scenario. A comparison wi…
Position paper - progress towards standards in integrated (aerobic) MBR modelling.
2020
Membrane bioreactor (MBR) models are useful tools for both design and management. The system complexity is high due to the involved number of processes which can be clustered in biological and physical ones. Literature studies are present and need to be harmonized in order to gain insights from the different studies and allow system optimization by applying a control. This position paper aims at defining the current state of the art of the main integrated MBR models reported in the literature. On the basis of a modelling review, a standardized terminology is proposed to facilitate the further development and comparison of integrated membrane fouling models for aerobic MBRs. ispartof: WATER …