Search results for " Simulation"
showing 10 items of 4034 documents
Targeting the aryl hydrocarbon receptor with a novel set of triarylmethanes
2020
International audience; The aryl hydrocarbon receptor (AhR) is a chemical sensor upregulating the transcription of responsive genes associated with endocrine homeostasis, oxidative balance and diverse metabolic, immunological and inflammatory processes, which have raised the pharmacological interest on its modulation. Herein, a novel set of 32 unsymmetrical triarylmethane (TAM) class of structures has been synthesized, characterized and their AhR transcriptional activity evaluated using a cell-based assay. Eight of the assayed TAM compounds (14, 15, 18, 19, 21, 22, 25, 28) exhibited AhR agonism but none of them showed antagonist effects. TAMs bearing benzotrifluoride, naphthol or heteroarom…
Steady, periodic, quasi-periodic and chaotic flow regimes in toroidal pipes
2012
Incompressible flow in a toroidal pipe was investigated by direct numerical simulation. The curvature a/c (radius of the cross section / radius of the torus) was 0.3 or 0.1 and the bulk Reynolds number ranged between 3500 and 14 700. The study revealed a rich scenario of transition to turbulence. For the higher curvature a/c = 0.3, a supercritical transition from stationary to periodic flow (Hopf bifurcation) was observed at Re=4600. The periodic flow was characterized by a travelling wave which, in the whole periodic Re range, took the form of a varicose modulation of the twin Dean vortex rings, included 8 wavelengths along the axis of the torus, and exhibited instantaneous anti-symmetry a…
Relation entre transitivité et structure de communauté dans les réseaux complexes
2011
The relation between community structure and other topological properties in complex networks, has not been analyzed clearly. In this preliminary study, we explore experimentally the potential link between transitivity and community structure. We study the evolution of transitivity based on the quality of the community structure on artificially generated networks. Then we observe the evolution of community structure according to transitivity value. The results show a relationship between high transitivity and community structure. Additional analytical work is needed to identify the exact nature of this relationship.
EFFECTS OF THE PENETRATION OF WIND POWER IN THE BRAZILIAN ELECTRICITY MARKET
2016
Climate variability has been the main driver for renewables in the Brazilian electricity market. This article analyzes the vulnerabilities of the dependence on hydropower in renewable energy production due to climate variation, as well as wind power penetration in Brazil, given a set of wind industry policies. Despite Brazilian renewable energy increase, the study shows the impact in energy supply in north region, due to the lack of transmission infrastructure. In Brazil, the potential trade-offs between renewables growth, and transmission infrastructure inconsistencies in terms of policy implementation are not yet well analyzed. Simulation results show the potential conflicts between energ…
Corrigendum to “Smooth and non-smooth traveling wave solutions of some generalized Camassa–Holm equations” [19 (6) (2014) 1746–1769]
2015
Corrigendum Corrigendum to ‘‘Smooth and non-smooth traveling wave solutions of some generalized Camassa–Holm equations’’ [19 (6) (2014) 1746–1769] M. Russo , S. Roy Choudhury , T. Rehman , G. Gambino b University of Central Florida, Department of Mathematics, 4000 Central Florida Blvd., Orlando, USA University of Palermo, Department of Mathematics and Computer Science, Via Archirafi 34, 90123 Palermo, Italy
Corrigendum to “Regular and singular pulse and front solutions and possible isochronous behavior in the short-pulse equation: Phase-plane, multi-infi…
2022
Section 7 of the original paper contained several errors which are corrected here. Equations (54) and (55) are incorrect. In the following, the corrected versions of these equations are given and the subsequent results of Section 7 are also revised.
Boundary-layer Flows Past an Hemispherical Roughness Element: DNS, Global Stability and Sensitivity Analysis
2015
Abstract We investigate the full three-dimensional instability mechanism arising in the wake of an hemispherical roughness element immersed in a laminar Blasius boundary layer. The inherent three-dimensional flow pattern beyond the critical Reynolds number is characterized by coherent vortical structures called hairpin vortices. Direct numerical simulation is used to analyze the formation and the shedding of hairpin packets inside the shear layer. The first bifurcation characteristics are investigated by global stability tools. We show the spatial structure of the linear direct and adjoint global eigenmodes of the linearized Navier-Stokes operator and use structural sensitivity analysis to …
Solving a large multicontainer loading problem in the car manufacturing industry
2017
Abstract Renault, a large car manufacturer with factories all over the world, has a production system in which not every factory produces all the parts required to assemble a vehicle. Every day, large quantities of car parts are sent from one factory to another, defining very large truck/container transportation problems. The main challenge faced by the Renault logistics platforms is to load the items into trucks and containers as efficiently as possible so as to minimize the number of vehicles sent. Therefore, the problem to be solved is a multicontainer loading problem in which, besides the usual geometric constraints preventing items from overlapping and exceeding the dimensions of the c…
Bidirectional labeling for solving vehicle routing and truck driver scheduling problems
2020
Abstract This paper studies the vehicle routing and truck driver scheduling problem where routes and schedules must comply with hours of service regulations for truck drivers. It presents a backward labeling method for generating feasible schedules and shows how the labels generated with the backward method can be combined with labels generated by a forward labeling method. The bidirectional labeling is embedded into a branch-and-price-and-cut approach and evaluated for hours of service regulations in the United States and the European Union. Computational experiments show that the resulting bidirectional branch-and-price-and-cut approach is significantly faster than unidirectional counterp…
A ride comfort tyre model for off-highway vehicles
2014
Tyre modelling is a major challenge when using time domain multibody simulation models to evaluate ride comfort on off-highway commercial vehicles. Further, parameters for these big tyres are difficult to obtain and thus, commercial car tyre models are difficult to apply. In this research work, a simple vertical tyre model for off-highway ride comfort evaluation is suggested. A displaced volume approach has been developed and combined with the slip theory to yield a tyre model that can be characterised by only three parameters. Full scale measurements on a dump truck have been carried out. Force responses from measurements are compared to the simulation results. Acceleration responses and t…