Search results for " Simulation"

Structural Parameters under Partial Least Squares and Covariance-Based Structural Equation Modeling : A Comment on Yuan and Deng (2021)

2023

In their article, Yuan and Deng argue that a structural parameter under partial least squares structural equation modeling (PLS-SEM) is zero if and only if the same structural parameter is zero under covariance-based structural equation modeling (CB-SEM). Yuan and Deng then conclude that statistical tests on individual structural parameters assessing the null hypothesis of no effect can achieve the same purpose in CB-SEM and PLS-SEM. Our response to their article highlights that the relationship they find between PLS-SEM and CB-SEM structural parameters is not universally valid, and that consequently, tests on individual parameters in CB-SEM and PLS-SEM generally do not fulfill the same pur…

Monotone generalized nonlinear contractions and fixed point theorems in ordered metric spaces

2011

The purpose of this paper is to present some fixed point theorems for T -weakly isotone increasing mappings which satisfy a generalized nonlinear contractive condition in complete ordered metric spaces. As application, we establish an existence theorem for a solution of some integral equations.

Enabling Energy Savings in Offshore Mechatronic Systems by using Self-Contained Cylinders

2019

This paper proposes a novel actuation system for an offshore drilling application. It consists of three self-contained electro-hydraulic cylinders that can share and store regenerated energy. The energy saving potential of the proposed solution is analyzed through a multibody system simulation. The self-contained system demonstrates superior energy efficiency compared to the benchmark system representing the state-of-the-art approach used today (i.e., valve-controlled cylinders by means of pressure-compensated directional control valves and counter-balance valves, supplied by a centralized hydraulic power unit). Due to the power on demand capability, the cancellation of the throttling losse…

ANALYSIS OF THE TRADITIONAL PASSIVE SYSTEMS PERFORMANCE THROUGH THE APPLICATION OF CFD SOFTWARE

2012

The need to reduce energy consumption is pushing the building design research to the evaluation of passive conditioning systems, since urban buildings are one of the major energy dissipater resulting in emission of CO2. This approach is not modern, but it is historically rooted in the architectural culture of the Mediterranean area and in the Middle East. The passive systems have ancient origins: they were developed to mitigate the summer heat and the winter cold. To understand the reasons that led to the development of passive systems, it should be remembered that about One-Fifth of the emerged planet surface and One-Third of the world's population live in conditions of warm-dry or hot-hum…

Iterative Learning Applied to Hydraulic Pressure Control

2018

This paper addresses a performance limiting phenomenon that may occur in the pressure control of hydraulic actuators subjected to external velocity disturbances. It is demonstrated that under certain conditions a severe peaking of the control error may be observed that significantly degrades the performance of the system due to the presence of nonlinearities. The phenomenon is investigated numerically and experimentally using a system that requires pressure control of two hydraulic cylinders. It is demonstrated that the common solution of feed forwarding the velocity disturbance is not effective in reducing the peaking that occurs as a result of this phenomenon. To improve the system perfor…

Impurity behaviour in JET-ILW plasmas fuelled with gas and/or with pellets: a comparative study with the transport code COREDIV

2021

Abstract This study deals with the comparison of impurity behaviour in pellet and gas fuelled JET-ITER like wall pulses with the aim of finding the mechanisms leading to the generally observed higher concentration of tungsten in pellet fuelled plasmas. In fact, tungsten is the main high-Z impurity in the JET-ILW plasmas and is responsible for most of the radiative losses in the plasma core. Analysis of the experimental data pertaining to pulses at different plasma currents, different input power and different electron densities is integrated by numerical modelling with the self-consistent fluid transport code COREDIV. Experimentally, and numerically, the ratio between the radiated power in …

Synthesis and Molecular Modeling Studies of Derivatives of a Highly Potent Peptidomimetic Vinyl Ester as Falcipain-2 Inhibitors

2012

Herein we report the synthesis of a set of constrained peptidomimetics endowed with an electrophilic vinyl ester warhead and structurally related to a previously identified lead compound, a potent and irreversible inhibitor of falcipain-2 (FP-2). FP-2 is the main hemoglobinase of the malaria parasite P. falciparum. The new compounds were evaluated for their inhibition against FP-2, and the results were rationalized on the basis of docking experiments. These studies underscore the pivotal role of both the ester function at the P1' site and the trifluoromethyl group of the P3 side chain in determining the correct orientation of the Michael acceptor warhead in the catalytic site, and as a cons…

The influence of others’ actions on perspective taking: Poster

2021

The influence of others’ actions on perspective taking: Oral presentation

2021

A study of Type B uncertainties associated with the photoelectric effect in low-energy Monte Carlo simulations

2021

The goal of this manuscript is to estimate Type B uncertainties in absorbed-dose calculations arising from the different implementations in current state-of-the-art Monte Carlo codes of low-energy photon cross-sections (<200 keV). Monte Carlo simulations are carried out using three codes widely used in the low-energy domain: PENELOPE-2018, EGSnrc, and MCNP. Mass energy-absorption coefficients for water, air, graphite, and their respective ratios; absorbed dose; and photon-fluence spectra are considered. Benchmark simulations using similar cross-sections have been performed. The differences observed between these quantities when different cross-sections are considered are taken to be a go…