Search results for " Sinus"

showing 10 items of 276 documents

Clinical, immunological, and molecular analysis in a large cohort of patients with X-linked agammaglobulinemia: an Italian multicenter study

2002

A questionnaire-based retrospective clinical and immunological survey was conducted in 73 males with a definite diagnosis of X-linked agammaglobulinemia based on BTK sequence analysis. Forty-four were sporadic and 29 familial cases. At December 2000, the patients' ages ranged from 2 to 33 years; mean age at diagnosis and mean duration of follow-up were 3.5 and 10 years respectively. After the mid-1980s all but 2 were on intravenous immunoglobulin (IVIG) substitution therapy, with residual IgG >500 mg/dl in 94% of the patients at the time of enrollment. Respiratory infections were the most frequent manifestation both prior to diagnosis and over follow-up. Chronic lung disease (CLD) was prese…

Lung DiseasesAdultMalePediatricsmedicine.medical_specialtyGenetic Linkage; Agammaglobulinemia; Humans; Infant Newborn; Protein-Tyrosine Kinases; Child; Child Preschool; X Chromosome; Immunoglobulins Intravenous; Lung Diseases; Adult; Cohort Studies; Chronic Disease; Follow-Up Studies; Adolescent; Mutation; Maleclinical featuresX ChromosomeX-linked agammaglobulinemiaAdolescentGenetic LinkageImmunologyX-linked agammaglobulinemiaImmunoglobulinsX-linked agammaglobulinemia; infections; intravenous immunoglobulin; BTK mutationSepsisCohort StudiesAgammaglobulinemiaImmunopathologyintravenous immunoglobulinEpidemiologymedicineAgammaglobulinaemia Tyrosine KinaseImmunology and AllergyHumansinfectionsChildPreschoolSettore MED/38 - Pediatria Generale e SpecialisticaBTK mutationsbusiness.industryChronic sinusitisInfant NewbornMeningoencephalitisImmunoglobulins IntravenousInfantProtein-Tyrosine Kinasesmedicine.diseaseNewbornBTK mutationagammaglobulinemia; clinical features; BTK mutationsChild PreschoolChronic DiseaseMutationbusinessIntravenousMeningitisCohort studyFollow-Up Studies
researchProduct

Two-dimensional transthoracic echocardiographic normal reference ranges for proximal aorta dimensions: Results from the EACVI NORRE study

2017

International audience; AIMS: To report normal reference ranges for echocardiographic dimensions of the proximal aorta obtained in a large group of healthy volunteers recruited using state-of-the-art cardiac ultrasound equipment, considering different measurement conventions, and taking into account gender, age, and body size of individuals. METHODS AND RESULTS: A total of 704 (mean age: 46.0 ± 13.5 years) healthy volunteers (310 men and 394 women) were prospectively recruited from the collaborating institutions of the Normal Reference Ranges for Echocardiography (NORRE) study. A comprehensive echocardiographic examination was obtained in all subjects following pre-defined protocols. Aortic…

MaleAorta ThoracicSex Factor030204 cardiovascular system & hematologyReproducibility of resultCohort Studies0302 clinical medicineDiastoleMedicineThoracic aortaAge FactorReference ValueProspective Studies030212 general & internal medicineMultivariate AnalysiBody surface areaCardiac cycleAge FactorsGeneral MedicineNORRE studyMiddle AgedHealthy VolunteerHealthy VolunteersEuropeEchocardiographyNORRE study; echocardiography; reference values; reproducibility of results; sinus of valsalva; thoracic aortaCardiologyLinear Model[SDV.IB]Life Sciences [q-bio]/BioengineeringFemaleCardiology and Cardiovascular MedicineHumanAdultmedicine.medical_specialtySystoleDiastoleNormal valuesThoracic aortaReference values03 medical and health sciencesYoung AdultSex FactorsInternal medicinemedicine.arteryAscending aortaHumansRadiology Nuclear Medicine and imagingMeasurement methodAortaAnalysis of Variancebusiness.industrySinus of valsalvaReproducibility of ResultsMED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLAREProspective StudieMultivariate AnalysisLinear ModelsCohort Studiebusiness
researchProduct

Intermediate filament protein profiles of human testicular non-seminomatous germ cell tumors: correlation of cytokeratin synthesis to cell differenti…

1991

Abstract The patterns of cytoskeletal differentiation were studied in 20 testicular non-seminomatous germ cell tumors by immunohistochemistry, using diverse monoclonal antibodies specific for different intermediate filament (IF) proteins and for desmoplakin. Immuno-fluorescence and immunoperoxidase methods on both formalin-fixed and frozen tissues were applied, in some cases together with a gel electrophoretic analysis of IF proteins. The tumors examined included embryonal carcinoma (EC), endodermal sinus tumor (EST), choriocar-cinoma and teratoma. Nine of the tumors were composed of only one histological type, the others showed mixed components. Cytokeratins 8 and 18 were identified in all…

MaleCancer ResearchPathologymedicine.medical_specialtyCellular differentiationFluorescent Antibody TechniqueVimentinBiologyEmbryonal carcinomaCytokeratinIntermediate Filament ProteinsTesticular NeoplasmsMesonephromamedicineHumansElectrophoresis Gel Two-DimensionalChoriocarcinomaIntermediate filamentMolecular BiologyTeratomaCell DifferentiationDesmosomesCell BiologyEndodermal sinus tumormedicine.diseaseImmunologybiology.proteinKeratinsTeratomaGerm cell tumorsDevelopmental BiologyDifferentiation
researchProduct

Occlusion of the pig superior sagittal sinus, bridging and cortical veins: multistep evolution of sinus-vein thrombosis

1992

✓ Cerebral sinus-vein thrombosis may lead to severe hemodynamic changes, elevated intracranial pressure (ICP), and brain edema. It is supposed that progression of the thrombus from the sinus into bridging and cortical veins plays a key role in the development of these pathophysiological changes, but this hypothesis lacks experimental proof. The aim of this study, using a novel animal model of sinus-vein thrombosis, was to evaluate the effects of a standardized occlusion of the superior sagittal sinus and its bridging and cortical veins on hemodynamic alterations, on brain water content, and on ICP in domestic pigs. In 10 animals, the middle third of the superior sagittal sinus was occluded …

MaleCerebral veinsIntracranial PressureSwinebusiness.industryBrainAnatomymedicine.diseaseCerebral VeinsThrombosisCerebral AngiographySinus Thrombosis Intracranialmedicine.anatomical_structureBody WaterCerebrovascular CirculationOcclusionmedicineAnimalsFemaleCerebral perfusion pressureFibrin gluebusinessSinus (anatomy)Intracranial pressureSuperior sagittal sinusJournal of Neurosurgery
researchProduct

Frequency of the odontogenic maxillary sinusitis extended to the anterior ethmoid sinus and response to surgical treatment

2014

Objectives: Odontogenic sinusitis usually affects the maxillary sinus but may extend to the anterior ethmoid sinuses. The purpose of this study is to determine the percentage of odontogenic maxillary sinusitis extended to the anterior ethmoid sinuses and determine also the surgical resolution differences between odontogenic maxillary sinusitis and odontogenic maxillary associated to anterior ethmoidal sinusitis. Study Design: This is a retrospective cohort study performed on 55 patients diagnosed of odontogenic sinusitis and treated surgically by functional endoscopic sinus surgery. Results: This study showed that 52.7% of odontogenic maxillary sinusitis spreads to anterior ethmoid, causing…

MaleEthmoid Sinusitismedicine.medical_specialtyMaxillary sinusDentistryOdontologíaCohort Studiesmedicineotorhinolaryngologic diseasesHumansSinusitisGeneral DentistryRetrospective StudiesEthmoid Sinusitisbusiness.industryResearchStomatognathic DiseasesEthmoidal SinusitisEthmoidectomyFunctional endoscopic sinus surgeryMiddle AgedMaxillary Sinusitismedicine.disease:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludeye diseasesOdontogenicSurgerymedicine.anatomical_structureOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASAnterior ethmoid sinusFemaleSurgeryOral Surgerybusiness
researchProduct

Maxillary Sinus Anatomy: A Cadaveric Study With Clinical Implications

2009

This study measured maxillary sinus volume, evaluated the location of the semilunar hiatus in correlation to the nasal floor, and the incidence, location, and height of antral septa and discusses their clinical implications. Maxillary sinus volume was quantified in 65 cadavers (130 sinuses) by water application through the semilunar hiatus and measuring the used amount. The location of the semilunar hiatus was identified as distance from the nasal floor. The septa were counted, evaluated, and the size measured from the antral floor. The medium maxillary sinus volume was 12.5 mL (range, 5-22 mL). The medium location of the semilunar hiatus was 25.6 mm above the nasal floor (range, 18-35 mm).…

MaleHistologyMaxillary sinusMandibular first molarMandibular second molarCadaverCadaverotorhinolaryngologic diseasesmedicinePremolarHumansJaw EdentulousEcology Evolution Behavior and SystematicsAgedAged 80 and overSemilunar hiatusbusiness.industryAnatomyMaxillary SinusMiddle Agedmedicine.anatomical_structureMaxillaFemaleAnatomybusinessCadaveric spasmBiotechnologyThe Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
researchProduct

A novel trephine design for sinus lift lateral approach. Case report

2010

Various techniques are described in the literature, either by crestal or lateral approach. Sinus augmentation has a high percentage of success, but presents a number of intraoperative and postoperative complications. The most frequent complication is the Schneiderian membrane perforation with a percentage of perforations between 11% and 56% according to authors. The aim of this study is to describe another membrane approach technique for the sinus lateral wall osteotomy that minimizes the risk of Schneiderian membrane perforation. We present a case of a 50 year old patient attended the University Dental Clinic (UDC) of International University of Catalonia for implant and crown treatment du…

MaleMaxillary sinusbusiness.industrymedicine.medical_treatmentPerforation (oil well)Sinus liftDentistryMaxillary SinusMiddle Aged:CIENCIAS MÉDICAS [UNESCO]OsteotomyOsteotomyDental Implantationmedicine.anatomical_structureOtorhinolaryngologyTrephineUNESCO::CIENCIAS MÉDICASMaxillary first molarHumansMedicineSurgeryImplantbusinessGeneral DentistrySinus (anatomy)Medicina Oral Patología Oral y Cirugia Bucal
researchProduct

Microsurgical treatment of midfacial tumours involving the skull base

1998

Various approaches to the base of the skull for the treatment of cranial base tumours are described in detail. Advantages and disadvantages of the particular approaches are discussed. This clinical experience is based on 303 neoplasms involving the base of the skull, operated on by the authors. Retrospective survival studies are presented and a review of the literature on the subject is discussed. Utilizing microsurgical techniques the 2-, 3- and 5-year survival rates were significantly improved. The functional and aesthetic outcomes were also dramatically superior compared with standard ablative procedures. Reconstructive postoperative strategies are suggested.

MaleMicrosurgerymedicine.medical_specialtyEstheticsmedicine.medical_treatmentSkull NeoplasmsNoseSkull Base NeoplasmsFacial BonesParanasal SinusesAblative casemedicineHumansNeoplasm InvasivenessSurvival rateRetrospective StudiesMouthSurgical approachbusiness.industryRetrospective cohort studyPlastic Surgery ProceduresMicrosurgeryCarcinoma Adenoid CysticMicrosurgical treatmentOsteotomySurgerySurvival RateSkullTreatment Outcomemedicine.anatomical_structureOtorhinolaryngologyNeoplasm InvasivenessCarcinoma Squamous CellFemaleRadiotherapy AdjuvantSurgeryOral SurgeryMeningiomabusinessCraniotomyJournal of Cranio-Maxillofacial Surgery
researchProduct

Gastritis and gastroesophageal reflux disease are strongly associated with non-allergic nasal disorders

2021

AbstractBackgroundGastroesophageal reflux disease (GERD) has been reported to be significantly associated with chronic rhinosinusitis, but the strength of the association is still debated.AimsTo evaluate the strength of the association between gastritis/GERD and non-allergic rhinitis (NAR)/allergic rhinitis (AR)/sinusitis.MethodsWe investigated 2887 subjects aged 20–84 years, who underwent a clinical visit in seven Italian centres (Ancona, Palermo, Pavia, Terni, Sassari, Torino, Verona) within the study on Gene Environment Interactions in Respiratory Diseases, a population-based multicase-control study between 2008 and 2014. Subjects were asked if they had doctor-diagnosed “gastritis or sto…

MaleNon-allergic rhinitisGastroesophageal reflux diseaseGastroenterologyAllergic rhinitis0302 clinical medicinePrevalenceNon-allergic rhiniti030223 otorhinolaryngologySinusitisRhinitisAged 80 and overeducation.field_of_studyMiddle AgedGastrititItalyGastritisGastroesophageal RefluxFemalePublic HealthGastritismedicine.symptomResearch ArticleAdultPulmonary and Respiratory Medicinemedicine.medical_specialtyPopulationGastrititsSettore MED/10 - Malattie Dell'Apparato RespiratorioNOHiatal herniaGastritits Gastroesophageal refux disease Allergic rhinitis Non-allergic rhinitis SinusitisYoung Adult03 medical and health sciencesAllergic rhinitis; Gastritits; Gastroesophageal reflux disease; Non-allergic rhinitis; SinusitisInternal medicineAllergic rhinitimedicineHumansGastroesophageal refux diseaseSinusitiseducationAgedlcsh:RC705-779business.industrylcsh:Diseases of the respiratory systemmedicine.diseaseRhinitis AllergicSinusitidigestive system diseases030228 respiratory systemRelative riskChronic DiseaseGERDAllergic rhinitis; Gastritits; Gastroesophageal reflux disease; Non-allergic rhinitis; Sinusitis Public HealthNon-allergic rhinitisbusinessEsophagitis
researchProduct

A Scanning Technique to Measure Regional Cerebral Blood Flow and Oxyhemoglobin Level

2001

OBJECTIVE: The application of a laser scanning technique to measure regional cerebral blood flow (CBF) and tissue hemoglobin oxygenation (HbO 2 ) using the rat closed cranial window preparation is described. METHODS: Twenty-nine male Wistar rats were used to consecutively measure local CBF by laser Doppler flowmetry and tissue HbO 2 by a microspectrophotometric method at multiple corresponding cortical locations. The scanning technique used a computer-controlled micromanipulator. Data from three experimental models are presented: the whisker stimulation model, the ischemia-reperfusion model, and the sinus-vein thrombosis model. Sequential changes in local CBF and HbO 2 data before, during, …

MaleOptics and PhotonicsIschemiaHemodynamicsStimulationBrain IschemiaPhysical StimulationLaser-Doppler FlowmetrymedicineAnimalsSagittal Sinus ThrombosisRats WistarBalayagebusiness.industryBrainOxygenationLaser Doppler velocimetrymedicine.diseaseThrombosisRatsCerebral blood flowSpectrophotometryCerebrovascular CirculationOxyhemoglobinsReperfusion InjuryVibrissaeAnesthesiaSurgeryNeurology (clinical)businessBiomedical engineeringNeurosurgery
researchProduct