Search results for " Smoke"
showing 10 items of 127 documents
Tobacco use in the third trimester of pregnancy and its relationship to birth weight. A prospective study in Spain
2015
Abstract Background Few studies have been carried out in Spain examining the use of tobacco amongst expectant mothers and its effect on birth weight. Aims To observe the proportion of expectant mothers who smoke during their pregnancy, and the impact of tobacco consumption on maternal and birth weight. We also aimed to identify the trimester of pregnancy in which tobacco use produced the greatest reduction in birth weight. Methods Prospective observational study in Spain. A random sampling strategy was used to select health centres and participant women. A total of 137 individuals were enrolled in the study. Exposure to tobacco was measured through a self-reported questionnaire. Regressions…
Counseling intervention to improve quality of life in patients with pre-existing acute myocardial infarction (AMI) or chronic obstructive pulmonary d…
2018
In the light of diagnostic and therapeutic advances, patients with a previous myocardial infarction or with a diagnosis of chronic obstructive pulmonary disease are vulnerable and need continuous monitoring over time. These pathological frameworks have a strong impact on the economy and on the status of the population and require effective and low-cost solutions.The objective of this clinical trial is to evaluate the efficacy in the short term of a telephone counseling intervention to modify the lifestyles of these two patient populations.In May 2015, all the patients included in the study underwent a questionnaire to evaluate their eating and smoking habits and their quality of life. After…
El humo del tabaco y su asociación con la caries dental en niños y niñas de 10 a 15 años atendidos en la unidad de odontología del departamento 9 de …
2011
Fundamentos: Recientemente se ha destacado el papel de la exposición al humo del tabaco ambiental en la etiología de la caries dental. El objetivo del trabajo es valorar la asociación entre la inhalación del humo del tabaco ambiental y la experiencia de caries en niños de entre 10 y 15 años. Métodos: Estudio descriptivo transversal, realizado en la Unidad de Odontología de Atención Primaria del Departamento 9 de Salud de la Comunidad Valenciana. Se seleccionó una muestra aleatoria de 380 niños. Se realizó una exploración clínica a cada uno y se les entregó un cuestionario de opinión y contacto con el humo del tabaco para cumplimentar de forma autoadministrada. Se determinó: índice CAOD, índ…
A systematic review of maternal smoking during pregnancy and fetal measurements with meta-analysis
2017
Maternal smoking during pregnancy is linked to reduced birth weight but the gestation at onset of this relationship is not certain. We present a systematic review of the literature describing associations between maternal smoking during pregnancy and ultrasound measurements of fetal size, together with an accompanying meta-analysis. Studies were selected from electronic databases (OVID, EMBASE and Google Scholar) that examined associations between maternal smoking or smoke exposure and antenatal fetal ultrasound measurements. Outcome measures were first, second or third trimester fetal measurements. There were 284 abstracts identified, 16 papers were included in the review and the meta-anal…
Fire safety investigation for road tunnel ventilation systems – An overview
2014
Abstract In recent years, research activities about fire events in tunnel have received a significant impulse, especially after several accidents. The Computational Fluid Dynamic (CFD) has a fundamental role about. Researchers have spent resources on various topics involving numerical tools as the performance of a ventilation system, the influence of this on the air flow motion in the tunnel or the methods for fire schematization, fire-induced smoke characterization, turbulence models, etc. One of the main phenomena to consider for the safety when a fire occurs in a tunnel is the possibility of the fire-induced smoke to rise the tunnel (backlayering). A well-designed ventilation system shal…
Mosses as Biomonitor of Air Pollution with Analytes Originating from Tobacco Smoke
2018
Abstract The aim of the carried out research was the assessment of the possibility to use a popular bioindicator - Pleurozium schreberi mosses as a biosensor of the air pollution in living quarters with the analytes originating from tobacco smoke. The moss bag method of active biomonitoring, popular in environmental studies, was applied; the method is based on exposing mosses collected in clean areas in the locations polluted with, for example, heavy metals. However, this experiment involved exposing mosses in living quarters, in which approximately 10 cigarettes were smoked daily (first room - kitchen). For the purpose of comparison, moss samples were also placed in another room (bedroom),…
Human HSP10 variants downregulation after cigarette smoke extract exposure in lung cells
2009
The impact of cigarette-smoke stress (a form of oxidative stress) on human lung fibroblasts and epithelial cells, particularly its effect on Hsp10 expression, has not been characterized despite the fact that a role for mitochondrial chaperonins in the development of lung diseases, ranging from chronic obstructive pulmonary disease to bronchial carcinogenesis, has been suggested (1). We studied the effects of non-lethal doses of cigarette smoke extract (CSE) on the expression of Hsp10 in human lung fibroblasts (HFL-1 line) and epithelial cells (16HBE line). Proteomics was carried out using 2D-IPG, silver stain, western blotting, and mass-spectrometry; mRNA was measured by RT-PCR. Database se…
Cigarette smoke promotes inflammasome‐independent activation of caspase‐1 and ‐4 leading to gasdermin D cleavage in human macrophages
2022
Mechanisms and consequences of gasdermin D (GSDMD) activation in cigarette smoke (CS)-associated inflammation and lung disease are unknown. GSDMD is a downstream effector of caspase-1, -8, and -4. Upon cleavage, GSDMD generates pores into cell membranes. Different degrees of GSDMD activation are associated with a range of physiological outputs ranging from cell hyperactivation to pyroptosis. We have previously reported that in human monocyte-derived macrophages CS extract (CSE) inhibits the NLRP3 inflammasome and shifts the response to lipopolysaccharide (LPS) towards the TLR4-TRIF axis leading to activation of caspase-8, which, in turn, activates caspase-1. In the present work, we investig…
Cellular and Molecular Signatures of Oxidative Stress in Bronchial Epithelial Cell Models Injured by Cigarette Smoke Extract
2022
Exposure of the airways epithelium to environmental insults, including cigarette smoke, results in increased oxidative stress due to unbalance between oxidants and antioxidants in favor of oxidants. Oxidative stress is a feature of inflammation and promotes the progression of chronic lung diseases, including Chronic Obstructive Pulmonary Disease (COPD). Increased oxidative stress leads to exhaustion of antioxidant defenses, alterations in autophagy/mitophagy and cell survival regulatory mechanisms, thus promoting cell senescence. All these events are amplified by the increase of inflammation driven by oxidative stress. Several models of bronchial epithelial cells are used to study the molec…
COVID-19 Y SU REPERCUSIÓN EN LAS ADICCIONES
2021
espanolObjetivo. Indagar acerca de la literatura cientifica emergente a nivel internacional sobre la repercusion de la pandemia por COVID-19 en las adicciones. Metodologia. La base de datos Web of Science se utilizo para analizar la literatura cientifica sobre la pandemia por COVID-19 y la influencia que esta pueda tener en el ambito de las adicciones. Resultados. Se identificaron 320 documentos, de los cuales 38 cumplieron los criterios de inclusion. Sobresalieron tres problematicas: el consumo de tabaco, opioides y alcohol. Segun la literatura incipiente, entre los consumidores de opiaceos existe el riesgo de aumento de las sobredosis, asi como un empeoramiento del binomio estres-alcohol …