Search results for " Sn"

Invecchiamento cerebrale, nutraceutici e neuroprotezione

2017

The nervous system requires a high and continuous energy requirement and despite the brain represents only 2% of the body weight it receives about 15% of the cardiac output and consumes 20% of oxygen. The neuronal activity therefore determines a significant increase in energy consumption thus favoring the fact that the brain, during aging, becomes the seat of crucial structural and functional changes that condition the health in a fundamental way.

The sicilian network for inflammatory bowel disease (SN-IBD): preliminary data on efficacy of biological therapy.

2017

Introduction: The monitoring of appropriateness, costs, and clinical outcomes of biological therapy in inflammatory bowel disease (IBD) is a relevant need. Aims & Methods: We aimed to evaluate all these issues in Sicily through a webbased network of all prescribing centers. The Sicilian Network for Inflammatory Bowel Disease (SN-IBD) is composed by a super Hub coordinator centre and five Hub plus ten Spoke centres. From January 2013, all IBD patients starting a biological agent (incident cases) or already on treatment (prevalent cases) were entered in a web based software. Herein we report data of incident cases about the efficacy of biological therapy after twelve weeks and one year of…

THE EFFECT OF CYP3A5 AND ABCB1 SINGLE NUCLEOTIDE POLYMORPHISMS ON TACROLIMUS DOSE REQUIREMENTS IN CAUCASIAN LIVER TRANSPLANT PATIENTS

2008

Women e-participation: glass ceiling decrease?

2012

This paper aims to review useful theoretical frame work able to encapsulate new frontiers of research on women political participation. In particular based on the feminist dichotomy of public and private sphere it investigates how Internet can enrol women in solving glass ceiling in political activism and participation considering its grassroots networked nature.

Collisionless shock heating of heavy ions in SN 1987A

2019

Astrophysical shocks at all scales, from those in the heliosphere up to the cosmological shock waves, are typically "collisionless", because the thickness of their jump region is much shorter than the collisional mean free path. Across these jumps, electrons, protons, and ions are expected to be heated at different temperatures. Supernova remnants (SNRs) are ideal targets to study collisionless processes because of their bright post-shock emission and fast shocks. Although optical observations of Balmer-dominated shocks in young SNRs showed that the post-shock proton temperature is higher than the electron temperature, the actual dependence of the post-shock temperature on the particle mass…

Indications of a Si-rich bilateral jet of ejecta in the Vela SNR observed with XMM-Newton

2017

Context. The Vela supernova remnant displays several ejecta, which are fragment-like features protruding beyond the front of its primary blast shock wave. They appear to be "shrapnel", bowshock-shaped relics of the supernova explosion. One of these pieces of shrapnel (A), located in the northeastern edge of the remnant, is peculiar because its X-ray spectrum exhibits a high Si abundance, in contrast to the other observed ejecta fragments, which show enhanced O, Ne, and Mg abundances. Aims. In this Letter we present the analysis of another ejecta fragment located opposite to shrapnel A with respect to the center of the shell, in the southwestern boundary of the remnant, named shrapnel G. We …

3D MHD modeling of the expanding remnant of SN 1987A : role of magnetic field and non-thermal radio emission

2018

Aims. We investigate the role played by a pre-supernova (SN) ambient magnetic field on the dynamics of the expanding remnant of SN 1987A and the origin and evolution of the radio emission from the remnant, in particular, during the interaction of the blast wave with the nebula surrounding the SN. Methods. We model the evolution of SN 1987A from the breakout of the shock wave at the stellar surface to the expansion of its remnant through the surrounding nebula by 3D MHD simulations. The model considers the radiative cooling, the deviations from equilibrium of ionization, the deviation from temperature-equilibration between electrons and ions, and a plausible configuration of the pre-SN ambie…

Supernova 1987A: a Template to Link Supernovae to their Remnants

2015

The emission of supernova remnants reflects the properties of both the progenitor supernovae and the surrounding environment. The complex morphology of the remnants, however, hampers the disentanglement of the two contributions. Here we aim at identifying the imprint of SN 1987A on the X-ray emission of its remnant and at constraining the structure of the environment surrounding the supernova. We performed high-resolution hydrodynamic simulations describing SN 1987A soon after the core-collapse and the following three-dimensional expansion of its remnant between days 1 and 15000 after the supernova. We demonstrated that the physical model reproducing the main observables of SN 1987A during …

Sicilian Network for Inflammatory Bowel Disease (SN-IBD). A propensity score-matched comparison of infliximab and adalimumab in naïve and non-naïve p…

2018

Background: In the absence of head-to-head trials, there is an unmeet need to better understand the relative effectiveness of different biologics in inflammatory bowel disease (IBD). The Sicilian Network for Inflammatory Bowel Disease (SN-IBD) is a group composed by all Sicilian centres which continuously enter in a web-based software all clinical data of IBD patients treated with biologics. Methods: Data of all incident Crohn’s disease (CD) patients treated with infliximab (IFX) and adalimumab (ADA) from January 2013 to April 2017 were extracted from the cohort of SN-IBD. Patients were divided in biologic-naïve and non-naïve, and the two groups were analysed singularly. We used a one-to-tw…

Projekts: Uzņēmuma AUTO un SKAISTUMA STUDIJAS izveidošana

2015

Maģistra darbā „Projekts: Uzņēmuma AUTO un SKAISTUMA STUDIJA izveidošana” ir izstrādāts biznesa plāns jauna divu līmeņu automobiļu remontdarbnīcas un skaistuma studijas uzņēmuma dibināšanai. Autovadītājām ikdienā bieži nākas saskarties ar situāciju, ka ir nepieciešams apmeklēt automobiļu remontdarbnīcu. Parasti šīs remontdarbnīcas ir vietas, kuras nav ērtas un kuru piedāvātais serviss ir gana nepievilcīgs sievietēm. Bieži sievietēm nākas saskarties ar nelaipnu attieksmi no servisa darbinieku puses. Kamēr tiek veikts automobiļu remonts, klientiem nākas gaidīt kādā mazā klientiem paredzētā vietā, kas nav visai ērta un laiks, kurš tiek pavadīts gaidot tiek neefektīvi izmantots. Mūsdienu ātrais…