Search results for " Sn"

Le chaudron social de la SNCF

2018

International audience; Dans les représentations collectives, la SNCF demeure un bastion syndical, voire l’un de ces derniers bastions compte tenu de la désyndicalisation – assez générale en France et en Europe –depuis une trentaine d’années. Elle est aussi le foyer de grèves récurrentes qui polarisent l’actualité et traduisent une approche des relations sociales en termes de luttes semblant elles aussi, pour de bonnes ou de mauvaises raisons, appartenir à un autre temps. Tout cela confère à l’entreprise ferroviaire une certaine coloration, une image de chaudron social régulièrement en ébullition, qui a fini par supplanter une vision plus moderniste ou technologique de la SNCF. Cette représ…

Novel triplet of flexor muscles in the posterior tentacles of the snail, Helix pomatia.

2012

The anatomy of three novel flexor muscles in the posterior tentacles of Helix pomatia is described. The muscles originate from the ventral side of the sensory pad and are anchored at different sites in the base of the tentacle stem. The muscles span the tentacle and always take the length of the stem which depends on the rate of tentacle protrusion indicating that the muscles are both contractile and extremely stretchable. The three anchoring points at the base of the stem determine three space axes along which the contraction of a muscle or the synchronous contraction of the muscles can move the tentacle in space.

Shilling, Squeezing, Sniping. A further explanation for late bidding in online second-price auctions

2021

Abstract Several studies provide empirical evidence for sniping (i.e., waiting until the last few seconds to bid) in second-price internet auctions, particularly in auctions at eBay . This evidence was regarded as puzzling and an anomaly for an extended period: How could sniping be consistent with rational behaviour in second-price auctions, where theory predicts that bids’ timing plays no role and there is no incentive to bid less than one’s private value. An essential contribution to this puzzling issue has been the insight by Bose and Daripa (2017) that late bidding is itself a response to the shilling. Their paper explains well late bidding for repeating auctions. However, late bidding …

The stable repression of mesenchymal program is required for hepatocyte identity: A novel role for hepatocyte nuclear factor 4α

2011

The concept that cellular terminal differentiation is stably maintained once development is complete has been questioned by numerous observations showing that differentiated epithelium may undergo an epithelial-to-mesenchymal transition (EMT) program. EMT and the reverse process, mesenchymal-to-epithelial transition (MET), are typical events of development, tissue repair, and tumor progression. In this study, we aimed to clarify the molecular mechanisms underlying these phenotypic conversions in hepatocytes. Hepatocyte nuclear factor 4α (HNF4α) was overexpressed in different hepatocyte cell lines and the resulting gene expression profile was determined by real-time quantitative polymerase…

An epistatic mini-circuitry between the transcription factors Snail and HNF4α controls liver stem cell and hepatocyte features exhorting opposite reg…

2011

Preservation of the epithelial state involves the stable repression of epithelial-to-mesenchymal transition program, whereas maintenance of the stem compartment requires the inhibition of differentiation processes. A simple and direct molecular mini-circuitry between master elements of these biological processes might provide the best device to keep balanced such complex phenomena. In this work, we show that in hepatic stem cell Snail, a transcriptional repressor of the hepatocyte differentiation master gene HNF4α, directly represses the expression of the epithelial microRNAs (miRs)-200c and-34a, which in turn target several stem cell genes. Notably, in differentiated hepatocytes HNF4α, p…

Il turbamento nella tradizione letteraria e il riso turbato di Pirandello

2010

Si ripercorre la declinazione del turbamento nella tradizione letteraria per soffermarsi sul modo nuovo di rappresentarlo a partire dall'Ottocento. Dopo aver evidenziato l'importanza di Leopardi e analizzato alcuni campioni di Verga, Capuana, De Roberto si sottolinea il valore di snodo assunto dal riso turbato di Pirandello.

The snail

2021

Polymorphisms of β-defensin genes in Valle del Belice dairy sheep

2011

The aim of this work was to study β-defensin 1 (SBD1) and β-defensin 2 (SBD2) genes in Valle del Belice dairy sheep in order to identify polymorphisms that can be utilized as markers of the analyzed genes, and search for the functional effects and roles of the identified polymorphisms (variation of the amino acid sequence of the protein and stability of mRNA molecule). The study was conducted on 300 randomly selected animals belonging to four flocks. A total of seven SNPs were identified, two in SBD1 and five in SBD2. The two SNPs identified in SBD2 coding region, at position 1659 and position 1667, were non-synonymous, leading to amino acid changes in the protein product. Nevertheless, the…

The dark side of phubbing in the workplace: Investigating the role of intrinsic motivation and the use of enterprise social media (ESM) in a cross-cu…

2022

Despite the increasing phenomena of supervisor phubbing (a counterproductive workplace behaviour of managers), very few studies have explored its outcomes in organisations. This study aims to bridge this gap by investigating the relationships between supervisor phubbing and key employee outcomes. We conducted two studies in cross-cultural settings. In Study 1, which was conducted in Pakistan (a collectivistic culture), we collected 370 useable responses through an online survey from the employees working in the service sector organisations. Study 2, which was conducted in the United States of America (an individualistic culture), utilised the Prolific data collection service to gather 352 r…

Impact of corporate governance on firm performance and total shareholder return of german listed companies

2017

Promocijas darba mērķis ir izpētīt attiecības starp būtiskākajām Vācijas Korporatīvās vadības sistēmas daļām un uzņēmumu sniegumu Vācijas kotētajos uzņēmumos, lai noteiktu elementus ar pozitīvu un negatīvu ietekmi uz uzņēmumu sniegumu un kopējo akcionāru peļņu, pamatojoties uz fundamentālo literatūru, iepriekšējo pētījumu analītisko izpēti un uz divu pētījumu - empīriskā kvantitatīvā pētījuma un kvalitatīvās ekspertu interviju aptaujas - pierādījumiem. Darbu noslēdz ieteikumi Valdības komisijai pārskatīt kodeksu attiecībā uz tā negatīvo ietekmi uz uzņēmuma darbību un izvairīšanos no riska, akcionāriem un uzraudzības padomju priekšsēdētājiem uzlabot sastāva struktūru un ieviest padomes darbā…