Search results for " Spectroscopy"

showing 10 items of 6851 documents

Near-infrared emitting fluorescent homobimetallic gold(I) complexes displaying promising in vitro and in vivo therapeutic properties

2021

International audience; Boron neutron capture therapy (BNCT) has the potential to specifically destroy tumor cells without damaging the tissues infiltrated by the tumor. BNCT is a binary treatment method based on the combination of two agents that have no effect when applied individually: 10B and thermal neutrons. Exclusively, the combination of both produces an effect, whose extent depends on the amount of 10B in the tumor but also on the organs at risk. It is not yet possible to determine the 10B concentration in a specific tissue using non-invasive methods. At present, it is only possible to measure the 10B concentration in blood and to estimate the boron concentration in tissues based o…

Boron Compoundsinorganic chemicalsCell SurvivalInfrared RaysAntineoplastic Agents01 natural sciencesMiceStructure-Activity Relationship03 medical and health sciencesOptical imagingCoordination ComplexesIn vivoDrug DiscoveryTumor Cells CulturedAza-bodipyAnimalsHumans[CHIM]Chemical SciencesNir fluorescenceComputingMilieux_MISCELLANEOUSCell ProliferationFluorescent Dyes030304 developmental biologyPharmacologyAza CompoundsMice Inbred BALB C0303 health sciencesDose-Response Relationship DrugMolecular Structure010405 organic chemistryChemistryOptical ImagingOrganic ChemistryNear-infrared spectroscopyNeoplasms ExperimentalGeneral MedicineFluorescenceIn vitro3. Good health0104 chemical sciencesBiophysicsGoldDrug Screening Assays AntitumorCancer cell lines
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Segregation of lipid in Ir-dye/DMPA mixed monolayers as strategy to fabricate 2D supramolecular nanostructures at the air–water interface

2008

A novel pseudospherical fluorinated iridium(III) derivative, Ir-dye/PF6, [Ir(F2-ppy)2(bpy)]PF6 (F2-ppy = 2-(2,4-difluoro)phenylpyridine, bpy = 2,2′-bipyridine), has been organized by using a lipid matrix, DMPA (dimyristoyl-phosphatidic acid), in several molar ratios at the air–water interface. The molecular organization of both components and the degree of miscibility in the different mixed films have been inferred by surface techniques such as π–A isotherms, ellipsometry, reflection spectroscopy, Brewster angle microscopy (BAM), and IR spectroscopy for the LB films, additionally the results have been discussed according to the additivity rule. The equimolecular Ir-dye/DMPA mixture leads to…

Brewster's angleChemistrySupramolecular chemistrychemistry.chemical_elementInfrared spectroscopyGeneral ChemistrySurface pressureMiscibilitysymbols.namesakeChemical engineeringEllipsometryMonolayerMaterials ChemistrysymbolsOrganic chemistryIridiumJournal of Materials Chemistry
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Dimerization control in the self-assembly behavior of copillar[5]arenes bearing ω-hydroxyalkoxy groups.

2012

Two novel copillar[5]arenes bearing ω-hydroxyalkoxy groups are synthesized and their self-assembly properties are studied by (1)H NMR spectroscopy, specific viscosity, and X-ray measurements. The copillar[5]arene 2b bearing a 6-hydroxyhexyloxy group exhibits a reversible self-assembly behavior, leading to the formation of the self-inclusion monomer and hugging dimers. The reversible self-assembly behavior can be controlled by tuning solvent, temperature, guest, and H-bond interaction. However, the copillar[5]arene 2a bearing a short 4-hydroxybutyloxy group does not show such a self-assembly behavior to the formation of the self-inclusion monomer and hugging dimers.

Bridged-Ring CompoundsModels Molecular1h nmr spectroscopyBearing (mechanical)Molecular StructureIntrinsic viscosityOrganic ChemistryPhotochemistrylaw.inventionSolventCrystallographychemistry.chemical_compoundMonomerchemistryGroup (periodic table)lawAlcoholsBenzene DerivativesDimerizationThe Journal of organic chemistry
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Emerging dynamics in surfactant-based liquid mixtures: octanoic acid/bis(2-ethylhexyl) amine systems.

2012

This work focuses on the dynamic phenomena emerging in self-assembled transient intermolecular networks formed when two different surfactants are mixed. In particular, the relaxation processes in liquid mixtures composed by bis(2-ethylhexyl)amine (BEEA) and octanoic acid (OA) in the whole composition range has been investigated by dielectric spectroscopy and Brillouin spectroscopy. A thorough analysis of all the experimental data consistently suggests that, mainly driven by acid-base interactions arising when the two surfactants are mixed, supra-molecular aggregates formation causes the slowing down of molecular dynamics. This, in turn, reflects to longer-range relaxations. These changes ha…

Brillouin SpectroscopyChemistryRelaxation (NMR)Intermolecular forceGeneral Physics and AstronomyConductivity..Dielectric spectroscopyMolecular dynamicsLiquid mixturesChemical physicsionic conductivitybis(2-ethylhexyl)amine octanoic acid dielectric spectroscopy Brillouin spectroscopy liquid mixturesOrganic chemistryIonic conductivitySelf-assemblyPhysical and Theoretical Chemistryionic conductivity; Liquid mixtures; Brillouin scatteringBrillouin scatteringSettore CHIM/02 - Chimica FisicaThe Journal of chemical physics
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Phoxonic Hybrid Superlattice

2015

We studied experimentally and theoretically the direction-dependent elastic and electromagnetic wave propagation in a supported film of hybrid PMMA (poly[methyl-methacrylate])-TiO2 superlattice (SL). In the direction normal to the layers, this one-dimensional periodic structure opens propagation band gaps for both hypersonic (GHz) phonons and near-UV photons. The high mismatch of elastic and optical impedance results in a large dual phoxonic band gap. The presence of defects inherent to the spin-coating fabrication technique is sensitively manifested in the band gap region. Utilizing Brillouin light scattering, phonon propagation along the layers was observed to be distinctly different from…

Brillouin zonePhotonMaterials scienceBrillouin SpectroscopyWave propagationbusiness.industryBand gapPhononSuperlatticeOptoelectronicsGeneral Materials SciencebusinessLight scatteringACS Applied Materials & Interfaces
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Drug Screening Boosted by Hyperpolarized Long-Lived States in NMR

2014

International audience; : Transverse and longitudinal relaxation times (T1ρ and T1 ) have been widely exploited in NMR to probe the binding of ligands and putative drugs to target proteins. We have shown recently that long-lived states (LLS) can be more sensitive to ligand binding. LLS can be excited if the ligand comprises at least two coupled spins. Herein we broaden the scope of ligand screening by LLS to arbitrary ligands by covalent attachment of a functional group, which comprises a pair of coupled protons that are isolated from neighboring magnetic nuclei. The resulting functionalized ligands have longitudinal relaxation times T1 ((1) H) that are sufficiently long to allow the powerf…

BromidesMagnetic Resonance SpectroscopyStereochemistryDrug Evaluation PreclinicalThiophenesLigands010402 general chemistry01 natural sciencesBiochemistrydynamic nuclear polarizationchemistry.chemical_compoundNMR spectroscopyCatalytic DomainDrug DiscoveryGeneral Pharmacology Toxicology and PharmaceuticsPharmacologySpins[CHIM.ORGA]Chemical Sciences/Organic chemistry010405 organic chemistryDrug discoveryOrganic ChemistryRelaxation (NMR)ProteinsNuclear magnetic resonance spectroscopyFull PapersLigand (biochemistry)0104 chemical sciencesCrystallographychemistryCovalent bondlong-lived statesExcited stateFunctional groupMolecular MedicineChemMedChem
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<title>Iodine and bromine resonance lamps in atmospheric research</title>

2003

For the first time previously developed iodine resonance spectra source has been tested in flash photolysis experiment. Quantitative measurements of concentration kinetics of iodine atomic species in a I2+O3 system are possible. The 183.038 nm resonance absorption transition of I(2P3/2) in previously developed EDL has been studied; dependence of self-absorption and self-reversal on iodine partial pressure in the discharge volume has been measured. The search for optimal conditions for an iodine EDL with minimized self-absorption and sufficient intensity were made. In condition of flash photolysis with previously described method it is possible to determine the emission temperature, oscillat…

BromineAbsorption spectroscopyOscillator strengthChemistryAnalytical chemistryAbsorption cross sectionFlash photolysisResonancechemistry.chemical_elementAbsorption (electromagnetic radiation)SpectroscopySPIE Proceedings
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Laser-induced plasma spectroscopy in near vacuum ultraviolet using ordinary spectrograph and ICCD

2002

An experimental setup to measure laser-induced plasma emission spectra with an ordinary Czerny-Turner spectrograph and intensified charge-coupled device in the near vacuum ultraviolet down to 130 nm is described. Spectra of bromine, chlorine and iodine were recorded to demonstrate the performance of the setup.

BromineMaterials sciencebusiness.industrychemistry.chemical_elementAstrophysics::Cosmology and Extragalactic AstrophysicsPlasmaLaserSpectral linelaw.inventionVacuum ultravioletOpticschemistrylawLaser-induced breakdown spectroscopyEmission spectrumbusinessSpectrographAstrophysics::Galaxy AstrophysicsLaser Induced Plasma Spectroscopy and Applications
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Lattice dynamics of wurtzite and rocksalt AlN under high pressure: Effect of compression on the crystal anisotropy of wurtzite-type semiconductors

2008

Raman spectra of aluminum nitride (AlN) under pressure have been measured up to $25\phantom{\rule{0.3em}{0ex}}\mathrm{GPa}$, i.e., beyond the onset of the wurtzite-to-rocksalt phase transition around $20\phantom{\rule{0.3em}{0ex}}\mathrm{GPa}$. The experimental pressure coefficients for all the Raman-active modes of the wurtzite phase are reported and compared to those obtained from ab initio lattice dynamical calculations, as well as to previous experimental and theoretical results. The pressure coefficients of all the Raman-active modes in wurtzite-type semiconductors (AlN, GaN, InN, ZnO, and BeO), as well as the relatively low bulk modulus and phase transition pressure in wurtzite AlN, a…

Bulk modulusPhase transitionMaterials scienceCondensed matter physicsCondensed Matter::Otherbusiness.industryAb initioNitrideCondensed Matter::Mesoscopic Systems and Quantum Hall EffectCondensed Matter PhysicsElectronic Optical and Magnetic MaterialsCondensed Matter::Materials Sciencesymbols.namesakeSemiconductorLattice (order)symbolsbusinessRaman spectroscopyWurtzite crystal structurePhysical Review B
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Sulfated Lupane Triterpene Derivatives and a Flavone C-Glycoside from Gypsophila repens

2007

A new sulfated lupane triterpene, Gypsophilin (1), and its glucosyl ester, Gypsophilinoside (2) were isolated from the roots of Gypsophila repens whereas a new flavone C-glycoside (3) was obtained from the aerial parts. Their structures were established as (3beta)-3-O-(sulfo)lup-20(29)-en-23,28-dioic acid (1), (3beta)-3-O-(sulfo)lup-20(29)-en-23,28-dioic acid -28-O-beta-D-glucopyranosyl ester (2) and luteolin-7-O-alpha-L-arabinopyranosyl-6-C-beta-glucopyranoside (3) by spectroscopic methods such as 1D and 2D NMR, HR-ESI-MS and FAB-MS.

C glycosidesSpectrometry Mass Electrospray IonizationMagnetic Resonance SpectroscopySpectrophotometry InfraredStereochemistrySaponinCaryophyllaceaeCaryophyllaceaeSpectrometry Mass Fast Atom BombardmentSulfuric Acid EstersPlant RootsTerpeneSulfationTriterpeneDrug DiscoveryGlycosidesGypsophilinosidechemistry.chemical_classificationbiologyPlant ExtractsChemistryHydrolysisGypsophila repensGeneral ChemistryGeneral MedicineSaponinsbiology.organism_classificationTriterpenesSpectrophotometry UltravioletTwo-dimensional nuclear magnetic resonance spectroscopyGypsophilinChemical and Pharmaceutical Bulletin
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