Search results for " Statistical"

showing 10 items of 1649 documents

A brief online transdiagnostic measure: Psychometric properties of the Overall Anxiety Severity and Impairment Scale (OASIS) among Spanish patients w…

2018

The Overall Anxiety Severity and Impairment Scale (OASIS) is a self-report questionnaire designed to evaluate the severity and functional impairment associated with anxiety. Given its transdiagnostic nature, it can be used indistinctly across anxiety and depressive disorders. In this study, the psychometric properties of the online version of the OASIS were evaluated in a Spanish clinical sample with emotional disorders. Patients (n = 583) with anxiety (n = 250) and depression (n = 333) with a mean age of 37.21 (SD = 12.22), underwent a diagnostic interview and questionnaires assessing anxiety, depression, positive and negative affect, and quality of life. Factorial structure, internal cons…

Male050103 clinical psychologyPsychometricsEmotionsSocial Scienceslcsh:MedicineTest validityAnxietySeverity of Illness Index0302 clinical medicineQuality of lifeMedicine and Health SciencesCutoffPsychologyDiagnosis Computer-AssistedComputer Networkslcsh:ScienceMultidisciplinaryDepression05 social sciencesMiddle AgedAnxiety DisordersConfirmatory factor analysisAnxietyFemalemedicine.symptomPsychologyClinical psychologyResearch ArticleAdultComputer and Information SciencesAdolescentPsychometricsNeuropsychiatric DisordersNeurosesSensitivity and Specificity03 medical and health sciencesYoung AdultRating scaleDiagnostic MedicineMental Health and PsychiatrymedicineHumans0501 psychology and cognitive sciencesAgedPsychiatric Status Rating ScalesDepressive DisorderInternetMood Disorderslcsh:RDiscriminant validityBiology and Life Sciences030227 psychiatryHealth CareSpainQuality of Lifelcsh:QFactor Analysis StatisticalPLoS ONE
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Confirmatory factor analysis and psychometric properties of the Spanish version of the Multidimensional Body-Self Relations Questionnaire-Appearance …

2015

The main aim of this study was to confirm the factorial structure of the Spanish version of the Multidimensional Body-Self Relations Questionnaire-Appearance Scales in early adolescents from 12 to 14 years. The sample included 355 participants, 189 girls and 166 boys, with ages ranging from 12 to 14 years old. The original MBSRQ-AS 5-factor structure was confirmed, and the model showed a good fit to the data: Appearance Evaluation, Appearance Orientation, Body Areas Satisfaction, Overweight Preoccupation, and Self-Classified Weight. The internal consistency of the test scores was adequate. Girls had higher score s than boys on Appearance Orientation, Overweight Preoccupation, and Self-Class…

Male050103 clinical psychologyconfirmatory factor analysisSocial PsychologyPsychometricsAdolescentPsychometricsbody image050109 social psychologyPersonal SatisfactionOverweightFactor structureDevelopmental psychologyInternal consistencySurveys and QuestionnairesmedicineBody ImageHumans0501 psychology and cognitive sciencesChildGeneral PsychologyApplied Psychology05 social sciencesReproducibility of ResultsSpanish versionearly adolescentsConfirmatory factor analysisTest (assessment)SpainPhysical Appearance BodyEarly adolescentsFemaleMBSRQ-ASmedicine.symptomPsychologyFactor Analysis Statistical
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Prevalence and severity of eating disorders: A comparison of DSM-IV and DSM-5 among German adolescents.

2016

Objective Changes in the DSM-5 eating disorders criteria sought to increase the clarity of the diagnostic categories and to decrease the preponderance of nonspecified eating disorders. The first objective of this study was to analyze how these revisions affect threshold and EDNOS/OSFED eating disorder diagnoses in terms of prevalence, sex ratios, and diagnostic distribution in a student sample. Second, we aimed to compare the impairment levels of participants with a threshold, an EDNOS/OSFED and no diagnosis using both DSM-IV and DSM-5. Method A sample of 1654 7th and 8th grade students completed self-report questionnaires to determine diagnoses and impairment levels in the context of an ea…

Male050103 clinical psychologymedicine.medical_specialtyAdolescentContext (language use)Affect (psychology)DSM-5GermanFeeding and Eating Disorders03 medical and health sciences0302 clinical medicineGroup differencesGermanySurveys and Questionnairesmental disordersEpidemiologyPrevalenceMedicineHumans0501 psychology and cognitive sciencesMedical diagnosisPsychiatryChildbusiness.industry05 social sciencesmedicine.diseaselanguage.human_language030227 psychiatryDiagnostic and Statistical Manual of Mental DisordersPsychiatry and Mental healthEating disorderslanguageFemalebusinessClinical psychologyThe International journal of eating disorders
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Impaired semantic processing during sentence reading in children with dyslexia: combined fMRI and ERP evidence

2008

Developmental dyslexia is a specific disorder of reading acquisition characterized by a phonological core deficit. Sentence reading is also impaired in dyslexic readers, but whether semantic processing deficits contribute is unclear. Combining spatially and temporally sensitive neuroimaging techniques to focus on semantic processing can provide a more comprehensive characterization of sentence reading in dyslexia. We recorded brain activity from 52 children (16 with dyslexia, 31 controls) with functional magnetic resonance imaging (fMRI) and event-related potentials (ERP) in two separate counterbalanced sessions. The children silently read and occasionally judged simple sentences with seman…

Male2805 Cognitive NeuroscienceBrain activity and meditationCognitive Neurosciencemedia_common.quotation_subject610 Medicine & healthbehavioral disciplines and activitiesBrain mappingDyslexiaReading (process)medicineImage Processing Computer-AssistedSemantic memoryHumansLongitudinal StudiesChildEvoked Potentialsmedia_commonTemporal cortexCerebral CortexIntelligence TestsBrain Mappingmedicine.diagnostic_testEcho-Planar Imaging10093 Institute of PsychologyDyslexiaElectroencephalography10058 Department of Child and Adolescent Psychiatrymedicine.diseaseMagnetic Resonance ImagingSemanticsOxygenNeurologyReading10036 Medical ClinicData Interpretation Statistical10076 Center for Integrative Human Physiology2808 NeurologySpeech Perception570 Life sciences; biologyFemaleFunctional magnetic resonance imagingPsychology150 Psychologypsychological phenomena and processesSentencePsychomotor PerformanceCognitive psychology
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Antilymphocyte Globulin for Prevention of Chronic Graft-versus-Host Disease.

2016

Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; BACKGROUND Chronic graft-versus-host disease (GVHD) is the leading cause of later illness and death after allogeneic hematopoietic stem-cell transplantation. We hypothesized that the inclusion of antihuman T-lymphocyte immune globulin (ATG) in a myeloablative conditioning regimen for patients with acute leukemia would result in a significant reduction in chronic GVHD 2 years after allogeneic peripheral-blood stem-cell transplantation from an HLA-identical sibling. METHODS We conducted a prospective, multicenter, open-label, randomized phase 3 study of ATG as part of …

Male:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Models Statistical::Proportional Hazards Models [Medical Subject Headings]T-LymphocytesPhases of clinical researchGraft vs Host Disease:Named Groups::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings]Linfocitos t:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Immunosuppressive Agent0302 clinical medicineTrasplante homólogoEstudios prospectivosMedicineCumulative incidenceProspective StudiesProspective cohort studyChildTransplantation Homologou:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Blood Proteins::Immunoproteins::Immunoglobulins::Antibodies::Immune Sera::Antilymphocyte Serum [Medical Subject Headings]Acute leukemia:Anatomy::Cells::Blood Cells::Leukocytes::Leukocytes Mononuclear::Lymphocytes::T-Lymphocytes [Medical Subject Headings]:Diseases::Pathological Conditions Signs and Symptoms::Pathologic Processes::Disease Attributes::Chronic Disease [Medical Subject Headings]:Named Groups::Persons::Age Groups::Child::Child Preschool [Medical Subject Headings]Medicine (all)IncidenceSuero antilinfocíticoGeneral MedicineMiddle AgedModelos de riesgos proporcionales3. Good healthHumanosSurvival Rate030220 oncology & carcinogenesis:Named Groups::Persons::Age Groups::Adolescent [Medical Subject Headings]Child PreschoolFemale:Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Immunologic Factors::Immunosuppressive Agents [Medical Subject Headings]Immunosuppressive AgentsHumanHomologousAdultmedicine.medical_specialty:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Longitudinal Studies::Prospective Studies [Medical Subject Headings]:Named Groups::Persons::Age Groups::Adult::Young Adult [Medical Subject Headings]AdolescentEnfermedad injerto contra huéspedDisease-Free Survival03 medical and health sciencesYoung AdultInternal medicine:Named Groups::Persons::Age Groups::Adult [Medical Subject Headings]HumansTransplantation HomologousSupervivencia sin enfermedadPreschoolSurvival rate:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Disease-Free Survival [Medical Subject Headings]:Named Groups::Persons::Age Groups::Child [Medical Subject Headings]Antilymphocyte SerumProportional Hazards ModelsTransplantationbusiness.industryEnfermedad crónicamedicine.diseaseInmunosupresoresAnti-thymocyte globulinSurgeryTransplantation:Diseases::Immune System Diseases::Graft vs Host Disease [Medical Subject Headings]Prospective Studie:Analytical Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures Operative::Transplantation::Transplantation Homologous [Medical Subject Headings]Graft-versus-host diseaseT-Lymphocyte:Check Tags::Female [Medical Subject Headings]Chronic DiseaseProportional Hazards ModelAdolescent; Adult; Antilymphocyte Serum; Child; Child Preschool; Chronic Disease; Disease-Free Survival; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Incidence; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Survival Rate; T-Lymphocytes; Transplantation Homologous; Young Adult; Medicine (all)business030215 immunology
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Incidence rates of narcolepsy diagnoses in Taiwan, Canada, and Europe: The use of statistical simulation to evaluate methods for the rapid assessment…

2018

Vacunación; Narcolepsia; Simulación y modelado: en Vacunació; Narcolèpsia; Simulació i modelització Vaccination; Narcolepsy; Simulation and modeling Background & objectives Vaccine safety signals require investigation, which may be done rapidly at the population level using ecological studies, before embarking on hypothesis-testing studies. Incidence rates were used to assess a signal of narcolepsy following AS03-adjuvanted monovalent pandemic H1N1 (pH1N1) influenza vaccination among children and adolescents in Sweden and Finland in 2010. We explored the utility of ecological data to assess incidence of narcolepsy following exposure to pandemic H1N1 virus or vaccination in 10 sites that use…

Male:Other subheadings::Other subheadings::/epidemiology [Other subheadings]medicine.medical_treatmentlcsh:Medicine:Other subheadings::Other subheadings::/drug therapy [Other subheadings]medicine.disease_causeGeographical locations:enfermedades del sistema nervioso::trastornos del sueño-vigilia::disomnias::trastornos intrínsecos del sueño::trastornos de somnolencia excesiva::narcolepsia [NarcolepsiaENFERMEDADES]Influenza A Virus H1N1 Subtype0302 clinical medicineRisk FactorsPandemicMedicine and Health SciencesInfluenza A virusMedicinePublic and Occupational Health030212 general & internal medicineYoung adultChildlcsh:Science:Otros calificadores::Otros calificadores::/tratamiento farmacológico [Otros calificadores]Aged 80 and overVaccinesMultidisciplinaryIncidenceSimulation and ModelingIncidence (epidemiology)Vaccination:Otros calificadores::Otros calificadores::/epidemiología [Otros calificadores]Middle AgedVaccination and ImmunizationEuropeVaccinationInfectious DiseasesNeurologyInfluenza VaccinesChild PreschoolsymbolsEngineering and TechnologyFemaleSafetyNarcolèpsia - TractamentAdjuvantResearch ArticleAdultCanadaAsiaAdolescentInfectious Disease ControlImmunologyTaiwanResearch and Analysis MethodsYoung Adult03 medical and health sciencessymbols.namesakeAdjuvants ImmunologicEnvironmental healthInfluenza HumanHumansComputer SimulationEuropean UnionPoisson regressionAgedTrastorns del sonNarcolepsySwedenModels Statisticalbusiness.industrylcsh:RInfant NewbornNarcolèpsia - EpidemiologiaInfantBiology and Life SciencesDyssomniasAge GroupsR - MedicineRelative riskSignal ProcessingPopulation Groupingslcsh:QPreventive MedicinePeople and placesSleep Disordersbusiness030217 neurology & neurosurgeryPLOS ONE
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Kinetic modelling of the intestinal transport of sarafloxacin. Studiesin situin rat andin vitroin Caco-2 cells

2005

The absorption kinetics of sarafloxacin, as a model of fluoroquinolone structure, were studied in the rat small intestine and in Caco-2 cells. The objective of the study was to investigate the mechanistic basis of the drug's intestinal transport in comparison with other members of the fluoroquinolone family and to apply a mathematical modelling approach to the transport process. In the rat small intestine, sarafloxacin showed dual mechanisms of intestinal absorption with a passive diffusional component and an absorptive carrier-mediated component. The characteristics of the animal study design made it suitable for population analysis, thus allowing the accurate estimation of transport param…

MaleAbsorption (pharmacology)Chemical PhenomenaAntimetabolitesPopulationPharmaceutical ScienceOxidative PhosphorylationIntestinal absorptionDiffusionchemistry.chemical_compoundAdenosine TriphosphateSarafloxacinAnti-Infective AgentsCiprofloxacinAnimalsHumansIntestinal MucosaRats WistarSodium AzideeducationAntibacterial agenteducation.field_of_studyModels StatisticalChemistry PhysicalBiological TransportLipidsRatsIntestinal AbsorptionchemistryBiochemistryPermeability (electromagnetism)BiophysicsSodium azideEffluxCaco-2 CellsEnergy MetabolismAlgorithmsFluoroquinolonesJournal of Drug Targeting
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Sport burnout inventory–Dual career form for student-athletes: Assessing validity and reliability in a Finnish sample of adolescent athletes

2020

Background: The pressure of pursuing an athletic career simultaneously with education may set adolescent student-athletes at risk for sport and school burnout. Although the 2 life domains of student-athletes are strongly intertwined, so far, there has not been an instrument for investigating sport burnout parallel to school burnout. The aim of the present study was to introduce a sport burnout measure for adolescents in a dual career context and investigate its validity and reliability by using confirmatory factor analysis. Methods: The participants were 391 student-athletes (51% females) who filled in a questionnaire of sport burnout and background variables in the beginning of upper secon…

MaleAdolescent athleteshealth care facilities manpower and servicesApplied psychologyValidityBurnout0302 clinical medicineSurveys and QuestionnairesSelf-esteemOrthopedics and Sports MedicineFinlandmedia_commonSCHOOL BURNOUTSchoolsDepression05 social sciencesYouth SportsDepressive symptomsSelf-esteemConfirmatory factor analysisDual careerRegular paperFemalePsychologylcsh:RC1200-1245psychological phenomena and processesClinical psychologyAdolescent515 Psychologymedia_common.quotation_subjectSport burnout inventoryeducationPhysical Therapy Sports Therapy and RehabilitationContext (language use)Sample (statistics)Burnout Psychological050105 experimental psychologyConfirmatory factor analysis03 medical and health scienceslcsh:GV557-1198.995health services administrationHumans0501 psychology and cognitive sciencesPERFECTIONISMlcsh:Sports medicineStudentslcsh:SportsSport task valuesReproducibility of Results030229 sport sciencesSelf ConceptDual (category theory)Cross-Sectional Studies516 Educational sciencesFactor Analysis Statisticalhuman activitiesJournal of Sport and Health Science
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Statistical power of disease cluster and clustering tests for rare diseases: A simulation study of point sources

2012

Abstract Two recent epidemiological studies on clustering of childhood leukemia showed different results on the statistical power of disease cluster and clustering tests, possibly an effect of spatial data aggregation. Eight different leukemia cluster scenarios were simulated using individual addresses of all 1,009,332 children living in Denmark in 2006. For each scenario, a number of point sources were defined with an increased risk ratio at centroid, decreasing linearly to 1.0 at the edge; aggregation levels were administrative units of Danish municipalities and squares of 5, 12.5 and 25 km 2 . Six statistical methods were compared. Generally, statistical power decreased with increasing s…

MaleAdolescentEpidemiologyDenmarkHealth Toxicology and MutagenesisGeography Planning and DevelopmentDisease clustercomputer.software_genreStatistical powerStatisticsCluster AnalysisHumansComputer SimulationPoint (geometry)Poisson DistributionChildCluster analysisSpatial analysisk-medians clusteringMathematicsStatistical hypothesis testingSpatial AnalysisLeukemiaModels StatisticalData CollectionIncidenceCentroidInfectious DiseasesChild PreschoolFemaleData miningcomputerSpatial and Spatio-temporal Epidemiology
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Nordic adolescents responding to demanding survey scales in boring contexts: Examining straightlining

2022

Introduction Straightlining, or identical responses across all items within a multi-item scale, is often taken as an indication that responses to all items in a questionnaire are of poor quality. The purpose of this study was to examine straightlining on two scales: The Sense of Unity Scale (SUS) and the short version of the Warwick-Edinburgh Mental Well-being Scale (SWEMWBS). Methods Data stem from the 2017–2018 data collections in four Nordic countries of the Health Behaviour in School-children study (HBSC) (15-year-old students only; 50.9% girls; n = 5928). Data were weighted to adjust for oversampling of Swedish-speaking Finnish students and to equalize sample size across countries. The…

MaleAdolescentPsychometricsSocial Psychologyvastauksetscaleskyselytutkimusmitta-asteikotpohjoismaalaisethenkinen hyvinvointisurveysnuoretSurveys and QuestionnairesDevelopmental and Educational PsychologyHumansadolescentsChildStudentsstraightliningquestionnairesPsychiatry and Mental healthNordic countriesPediatrics Perinatology and Child HealthQuality of LifeFemaleFactor Analysis Statisticalsurvey-tutkimusJournal of Adolescence
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