Search results for " Steroids"
showing 6 items of 26 documents
Pediatric Recurrent Pericarditis: Appropriateness of the Standard of Care and Response to IL-1 Blockade
2022
Objective: To analyze, in a cohort of pediatric patients with recurrent pericarditis undergoing anti-interleukin (IL)-1 treatment: the agent and dosing used as first-line treatment, the long-term efficacy of IL-1 blockers, the percentage of patients achieving a drug-free remission, and the presence of variables associated with drug-free remission. Study design: Data were collected from patients' charts. The annualized relapse rate (ARR) was used for evaluation of treatment efficacy, and bivariate logistic regression analysis was used for variables associated with drug-free remission. Results: Fifty-eight patients, treated between 2008 and 2018, were included in the study (mean follow-up. 2.…
Esteroide anabolizanteak. Goi mailako kirol alorretik gimnasioetara
2013
El presente estudio pretende caracterizar sociológicamente el consumidor recreativo de esteroides anabolizantes en tierras valencianas. La investigación se desarrolla así a partir de la aplicación de una metodología explícitamente cualitativa y la puesta en práctica de la técnica de la entrevista semiestructurada. El perfil sociológico del consumidor recreativo de esteroides anabolizantes se caracteriza por un bajo nivel de estudios, cierta inestabilidad laboral vinculada a menudo con el mundo del ocio nocturno y de la seguridad tanto privada como pública, problemas familiares, gusto por las discotecas y la playa, y frecuentes rupturas en sus relaciones de pareja, entre otros aspectos. Se c…
Adverse Effects of Anabolic-Androgenic Steroids: A Literature Review
2021
Anabolic-androgenic steroids (AASs) are a large group of molecules including endogenously produced androgens, such as testosterone, as well as synthetically manufactured derivatives. AAS use is widespread due to their ability to improve muscle growth for aesthetic purposes and athletes’ performance, minimizing androgenic effects. AAS use is very popular and 1–3% of US inhabitants have been estimated to be AAS users. However, AASs have side effects, involving all organs, tissues and body functions, especially long-term toxicity involving the cardiovascular system and the reproductive system, thereby, their abuse is considered a public health issue. The aim of the proposed review is to highli…
Decreased serum levels of sex steroids associated with osteoporosis in a group of Romanian male patients
2016
Abstract Introduction. With age, sex hormone deficiency leads to reduced bone mineral density (BMD) in men. The aim of our research is to analyze the role of serum sex steroids in assessing BMD in the men included in this study. Materials and methods. This cross-sectional study included 146 men aged 65-85 years old with osteopenia or osteoporosis (study group) and 121 men with normal BMD (control group). Serum levels of total testosterone (Tt) and free testosterone (Tf) were measured by immunoassay, and estradiol (E2) levels were measured by the immunoenzymatic method. Femoral neck and lumbar spine BMD was examined by dual-energy X-ray absorptiometry. Results. Tf and E2 deficiency was signi…
Nuove dipendenze del terzo millennio: l'utilizzo di steroidi anabolizzanti come sostanza d'abuso
2005
Obiettivo. L'abuso di sostanze anabolizzanti si sta configurando come un problema di rilevanza psicosociale. L'uso di steroidi anabolizzanti in questi ultimi anni si è spostato dalla pratica sportiva professionale allo sport amatoriale e ad ambiti occupazionali particolari (buttafuori, modelli, ect.). La letteratura indica l'assuntore di steroidi come un poliassuntore che mette in atto condotte pericolose e aggressive per sé e per gli altri. L'obiettivo di questo studio è indagare le abitudini, le condotte di vita e il profilo psicologico di un gruppo di soggetti che frequentano centri sportivi nella città di Palermo (Italia), per verificare come l'utilizzo sconsiderato di sostanze anaboliz…
Inter‐individual variation of the urinary steroid profiles in Swedish and Norwegian athletes
2020
The steroidal module of the Athlete Biological Passport (ABP) aims to detect doping with endogenous steroids, e.g. testosterone (T), by longitudinally monitoring several biomarkers. These biomarkers are ratios combined of urinary concentrations of testosterone and metabolically related steroids. However, it is evident after five years of monitoring steroid passports, that there are large variations in the steroid ratios complicating its interpretation. In this study, we used over 11 000 urinary steroid profiles from Swedish and Norwegian athletes to determine both the inter‐ and intra‐individual variations of all steroids and ratios in the steroidal passport. Furthermore, we investigated if…