Search results for " Strategies"
showing 10 items of 514 documents
Literary critical narrative in latvian daily press
2013
Promocijas darba LITERATŪRKRITISKAIS NARATĪVS LATVIEŠU DIENAS PRESĒ Anotācija Promocijas darbā Literatūrkritiskais naratīvs dienas presē latviešu dienas laikrakstu literatūrkritiskie naratīvi tiek analizēti ar semiotiskā komunikācijas modeļa palīdzību. Literatūrkritiskie naratīvi veido daļu no mediju kultūras komunikācijas procesa un sastāv no zīmēm – semantiskām un sintaktiskām makrostruktūrām, kas radušās semiotiskas darbības rezultātā. Makrostruktūru klātbūtne un izvietojums tekstā nosaka laikrakstu literatūrkritiskā teksta tipus. Promocijas darbā analizētie preses teksti sistematizēti, veidojot sešus tipus: grāmatu recenzijas, īsās ziņas, intervijas, blogus, garākus avīžrakstus un inter…
Exploring translation strategies in video game localization
2012
This paper addresses the issue of video game localisation focusing on the different strategies to be used from the point of view of Translation Studies. More precisely, the article explores the possible relation between the translation approaches used in the field and the different genres or textual typologies of video games. As the narrative techniques and the story lines of video games have become more complex and well-developed, the adaptation of games entails a serious challenge for translators. Video games have evolved into multimodal and multidimensional products and new approaches and insights are required when studying the adaptation of games into different cultures. Electronic ente…
Novel therapeutic strategies for patients with NSCLC that do not respond to treatment with EGFR inhibitors
2014
Abstract: Introduction: Treatment with epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) yields tumour responses in non-small cell lung cancer (NSCLC) patients harbouring activating EGFR mutations. However, even in long-lasting responses, resistance to EGFR TKIs invariably occurs. Areas covered: This review examines resistance mechanisms to EGFR TKI treatment, which mainly arise from secondary EGFR mutations. Other resistance-inducing processes include mesenchymal-epithelial transition factor (MET) amplification, epithelial-mesenchymal transformation, phenotypic change from NSCLC to small-cell lung carcinoma, and modifications in parallel signalling pathways. Current…
New Potential Therapeutic Approach for the Treatment of B-Cell Malignancies Using Chlorambucil/Hydroxychloroquine-Loaded Anti-CD20 Nanoparticles
2013
Current B-cell disorder treatments take advantage of dose-intensive chemotherapy regimens and immunotherapy via use of monoclonal antibodies. Unfortunately, they may lead to insufficient tumor distribution of therapeutic agents, and often cause adverse effects on patients. In this contribution, we propose a novel therapeutic approach in which relatively high doses of Hydroxychloroquine and Chlorambucil were loaded into biodegradable nanoparticles coated with an anti-CD20 antibody. We demonstrate their ability to effectively target and internalize in tumor B-cells. Moreover, these nanoparticles were able to kill not only p53 mutated/deleted lymphoma cell lines expressing a low amount of CD20…
Membrane bioreactors sludge: From production to disposal
2020
Abstract This chapter reviews the MBR activated sludge from production to disposal. Starting from sludge characterization, the chapter first presents the features of MBR sludge (morphology and EPS chemical composition), also in terms of differences with the activated sludge from conventional activated sludge plants. Sludge dewaterability is then discussed, focusing on the differences between aerobically and anaerobically digested sludge. An analysis of the costs related to MBR sludge treatment and disposal also is presented in order to provide a framework for a sustainable MBR sludge management.
Age-dependent allocation of carotenoids to coloration versus antioxidant defences.
2009
SUMMARYAging is commonly attributed to age-related changes in oxidative damage due to an increased production of reactive oxygen species (ROS) and a weakened efficacy of enzymatic antioxidants. These age-related changes might therefore modify the use of dietary antioxidants, including carotenoids. As carotenoids are closely associated with the expression of secondary sexual signals, the allocation of carotenoids to sexual signal versus antioxidant defences may vary with age. In this study, we explored how carotenoid-based ornament and antioxidant activity varied with age and how an inflammatory-induced oxidative burst affected ornament and antioxidant activity across a range of ages. Using …
Relationship between Cyberbullying, Motivation and Learning Strategies, Academic Performance, and the Ability to Adapt to University
2021
Cyberbullying has become a frequent relational problem among young people, which has made it necessary to evaluate and prevent it in the university setting. The aim of this study is to examine the relationship between cyberbullying, motivation and learning strategies, the ability to adapt to university, and academic performance. A sample of 1368 Spanish university students (64% female) was administered a battery consisting of the European Bullying Intervention Project Questionnaire, the Learning and Study Strategies Inventory Short version, and the Student Adaptation to College Questionnaire, with their academic performance also being studied. The results found that the victimized bullies h…
Revisiting the multidimensional interaction model of stress, anxiety and coping during the COVID-19 pandemic: a longitudinal study
2022
Abstract Background Although the Multidimensional Interaction Model of Stress, Anxiety and Coping (MIMSAC) has been known for years, there is a lack of research examining this theory longitudinally in stressful events. This study aims to revisit the MIMSAC among university students during the COVID-19 pandemic. Methods A prospective cohort study with the longitudinal design was performed during the first (W1, March 30–April 29, 2020) and second wave (W2, November 3–December 3, 2020) of the COVID-19 pandemic. A total of 216 university students with a mean age of 22 years (ranging from 20 to 36, M = 22.13, SD = 2.04) participated in the study. An online survey included Perceived Stress Scale,…
Implicit Learning in Children Is Not Related to Age: Evidence from Drawing Behavior
2000
Three experiments are reported on implicit learning in 432 children between the ages of 4 and 10 years, using a new paradigm ("the neutral parameter procedure") based on drawing behavior. The first two experiments demonstrated that children modified their drawing behavior following specially devised practice in such a way that these modifications could not be viewed as the result of deliberate adaptive strategies. The third experiment showed that these behavioral modifications lasted for at least 1 hr after the training phase. No age-related differences appeared in the experiments. A comparison of children's data with similar adults' data also failed to reveal any age differences. These res…
Are changes in pain, cognitive appraisals and coping strategies associated with changes in physical functioning in older adults with joint pain and c…
2019
Background As the population ages, the number of people with chronic diseases increases. Frequently, older people suffer from joint pain together with other chronic diseases, which can lead to decreased physical functioning. Aims To investigate the associations of the changes in cognitive appraisals, coping strategies and pain with the change in physical functioning in older people, who have chronic pain and chronic diseases. Methods Elderly persons (n = 407, mean age 77 years, and 62% female), with self-reported joint pain and at least two chronic diseases, filled in questionnaires about cognitive appraisals, coping strategies, pain intensity and physical functioning at baseline, at 6- and…