Search results for " Strategy"

Transarterial radioembolization for hepatocellular carcinoma: a review

2016

Rodolfo Sacco,1 Caterina Conte,2 Emanuele Tumino,1 Giuseppe Parisi,1 Sara Marceglia,3 Salvatore Metrangolo,1 Roberto Eggenhoffner,4 Giampaolo Bresci,1 Giuseppe Cabibbo,5 Luca Giacomelli4 1Department of Gastroenterology, Cisanello Hospital, Pisa, 2Endocrinology and Metabolic Diseases, Policlinico A. Gemelli, Università Cattolica del Sacro Cuore, Rome, 3Department of Engineering and Architecture, University of Trieste, Trieste, 4Department of Surgical Sciences and Integrated Diagnostics, School of Medicine, Genova University, Genoa, 5Section of Gastroenterology, DIBIMIS, University of Palermo, Palermo, Italy Abstract: Hepatocellular carcinoma (HCC) is the most common type of liver canc…

Lung cancer: does age affect treatment strategy?

2009

Does firm’s network position enhance open innovation performance? Evidences from the biopharmaceutical industry

2013

This paper explores the relationship between open innovation (OI) and firm's network position on enhancing firm's innovation performance, such as new product development (NPD). We build a theoretical framework and test it on the biopharmaceutical context. Our result shows how firm's network position influences NPD performance obtained through OI practices.

Diversification and performance in the mobile app market: The role of the platform ecosystem

2019

Abstract We examine the effect of app developers' product line diversification decision on their performance and shed light on whether the type of platform ecosystem (open versus closed) where they commercialize apps influences this effect. We compare the revenue performance of diversified and specialized developers in Apple's App Store and Google Play. We show that in the Apple's App Store (closed platform) diversified developers always display lower performance than their specialized counterparts. In Google Play (open platform) diversification is beneficial in categories where diversified developers have predominant market share, whereas it is detrimental in categories dominated by specia…

An Effort-Accuracy Framework for IIMT

2011

In this chapter, we analyze to what extent INTACMATO meets the requirement of low effort. We take an existing effort-accuracy model, adapt and extend it to INTACMATO and show analytically the savings of effort achieved.

Opportunities and pitfalls related to e-commerce strategies in small-medium firms: A system dynamics approach

2002

E-commerce is often perceived as a powerful lever to foster growth of SMEs. However, both the literature and empirical evidence have shown the perils hidden in superficial decision making by SME entrepreneurs. A system dynamics (SD) approach is used in this article to demonstrate how managing processes of accumulation and depletion of strategic assets, detecting inertial effects of decisions made in the past, and selectively acting on policy levers are likely to help entrepreneurs in understanding opportunities and pitfalls related to e-commerce strategies. A feedback analysis of three case studies selected from the literature and the main findings from a survey conducted by the authors on …

Base-isolated structure equipped with tuned liquid column damper: An experimental study

2019

Abstract In this study, a novel passive vibration control strategy is investigated experimentally, where a Tuned Liquid Column Damper protects a base-isolated structure. The Tuned Liquid Column Damper is attached to the base, in contrast to typical attachment points of passive energy dissipation devices in high-rise buildings at elevated levels. Experiments on a base-excited small-scale three-story shear frame are conducted in order to study effects of both control devices – base-isolation and Tuned Liquid Column Damper – on the structural model. The dynamic properties of the stand-alone shear frame and the base-isolation subsystem are derived using standard dynamic test methods based on di…

Optimal design of complex passive-damping systems for vibration control of large structures: An energy-to-peak approach

2014

Published version of an article in the journal: Abstract and Applied Analysis. Also available from the publisher at: http://dx.doi.org/10.1155/2014/510236 Open Access We present a new design strategy that makes it possible to synthesize decentralized output-feedback controllers by solving two successive optimization problems with linear matrix inequality (LMI) constraints. In the initial LMI optimization problem, two auxiliary elements are computed: a standard state-feedback controller, which can be taken as a reference in the performance assessment, and a matrix that facilitates a proper definition of the main LMI optimization problem. Next, by solving the second optimization problem, the …

An original multi-objective criterion for the design of small-scale polygeneration systems based on realistic operating conditions

2008

The optimal design and operation of cogeneration and trigeneration systems for buildings applications is a complex issue, which has been investigated by several different approaches. Both the two basic management strategies, namely heat-tracking and electricity-tracking, have advantages and drawbacks in terms of operating results and may lead the plant designer either to undersize or oversize the CHP unit with respect to the optimal lay-out. Experimental works have demonstrated how the actual on-site performance of small-scale polygeneration systems significantly differs from their expected operation, due to the need for a regular plant operation and the effects of outages for scheduled or …

Shakedown optimal design of reinforced concrete structures by evolution strategies

2000

Approaches the shakedown optimal design of reinforced concrete (RC) structures, subjected to variable and repeated external quasi‐static actions which may generate the well‐known shakedown or adaptation phenomenon, when constraints are imposed on deflection and/or deformation parameters, in order to simulate the limited flexural ductility of the material, in the presence of combined axial stress and bending. Within this context, the classical shakedown optimal design problem is revisited, using a weak upper bound theorem on the effective plastic deformations. For this problem a new computational algorithm, termed evolution strategy, is herein presented. This algorithm, derived from analogy …