Search results for " Stroke."

showing 10 items of 313 documents

Endothelial Dysfunction and Inflammation in Ischemic Stroke Pathogenesis

2020

: Stroke is a heterogeneous disease, and within the broad category of brain ischemia and its subtypes vary dramatically in its etiology. : The endothelium can regulate the vascular homeostasis by modulating processes of vascular dilation and constriction by producing and secreting cytokines and chemical mediators, and inflammation represents one of the most important factors that contribute to alteration in vessel structure and function by dysregulation of this fine balance. : Endothelial dysfunction means a basic determinant of the vascular damage, which can be identified in all different clinical subtypes of stroke, and, recently, it has been recognized as an interesting determinant of c…

EndotheliumInflammationDiseaseBioinformatics01 natural sciencesBrain IschemiaBrain ischemiaPathogenesis03 medical and health sciencesIschemicDrug DiscoverymedicineHumansEndotheliumEndothelial dysfunctionStrokeIschemic Stroke030304 developmental biologyInflammationPharmacology0303 health sciencesbusiness.industrymedicine.disease0104 chemical sciencesStroke010404 medicinal & biomolecular chemistrymedicine.anatomical_structureEtiologyEndothelium Vascularmedicine.symptombusinessHumanCurrent Pharmaceutical Design
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Heat stroke risk for open-water swimmers during long-distance events.

2013

Open-water swimming is a rapidly growing sport discipline worldwide, and clinical problems associated with long-distance swimming are now better recognized and managed more effectively. The most prevalent medical risk associated with an open-water swimming event is hypothermia; therefore, the Federation Internationale De Natation (FINA) has instituted 2 rules to reduce this occurrence related to the minimum water temperature and the time taken to complete the race. Another medical risk that is relevant to open-water swimmers is heat stroke, a condition that can easily go unnoticed. The purpose of this review is to shed light on this physiological phenomenon by examining the physiological re…

Engineeringmedicine.medical_specialtyHeat exhaustionHeat StrokePhysical ExertionPoison controlbody composition water sport skin temperature body temperature triathlon swimmingSuicide preventionRisk AssessmentStroke riskRisk FactorsInjury preventionmedicineHumansSwimmingbusiness.industrySettore BIO/16 - Anatomia UmanaPublic Health Environmental and Occupational HealthTemperatureWatermedicine.diseaseOpen waterWater temperatureEmergency MedicinePhysical therapybusinessRisk assessmentWildernessenvironmental medicine
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Safety and Outcome of Revascularization Treatment in Patients With Acute Ischemic Stroke and COVID-19: The Global COVID-19 Stroke Registry.

2023

Background and ObjectivesCOVID-19–related inflammation, endothelial dysfunction, and coagulopathy may increase the bleeding risk and lower the efficacy of revascularization treatments in patients with acute ischemic stroke (AIS). We aimed to evaluate the safety and outcomes of revascularization treatments in patients with AIS and COVID-19.MethodsThis was a retrospective multicenter cohort study of consecutive patients with AIS receiving intravenous thrombolysis (IVT) and/or endovascular treatment (EVT) between March 2020 and June 2021 tested for severe acute respiratory syndrome coronavirus 2 infection. With a doubly robust model combining propensity score weighting and multivariate regress…

Fibrinolytic Agents/therapeutic useCerebral Hemorrhage/complicationsStroke/epidemiologyBrain Ischemia/complicationsTreatment OutcomeIschemic Stroke/epidemiologyCOVID-19/complicationsHumansCohort studiesEndovascular Procedures/adverse effectsRegistriesNeurology (clinical)610 Medicine & healthIntracranial Hemorrhages/etiologyThrombolytic Therapy/adverse effectsResearch Article
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Development and validation of a 5 stroke engine for range extenders application

2014

International audience; A 5-stroke turbo-charged port-injection spark-ignition engine has been developed in the present study for use as a range extender or series-hybrid main power source. The development and the design of the engine are based on 0D/1D model and experimental results have been compared with the engine model. The 5-stroke engine is a three-cylinder in which two cylinders perform a four-stroke cycle and alternatively a second expansion of the burnt gases is performed in the third cylinder. The boost pressure delivered by the turbocharger is controlled by a particular innovative system called “smart wastegate”, different from a conventional wastegate, consisting in a variable …

Five strokeEngineeringEnergy Engineering and Power TechnologyMechanical engineeringInternal combustion engines7. Clean energyAutomotive engineeringCylinder (engine)law.invention[SPI]Engineering Sciences [physics]law[INFO]Computer Science [cs]HybridizationPetrol engineWastegateRenewable Energy Sustainability and the Environmentbusiness.industryRange extenderFuel TechnologyIntegrated engine pressure ratioNuclear Energy and EngineeringInternal combustion engineEngine efficiencyCompression ratiobusinessEngine control unitHigh efficiency
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Analysis of Upper Limbs Target-Reaching Movement and Muscle Co-Activation in Patients with First Time Stroke for Rehabilitation Progress Monitoring

2022

In this paper, the authors analysed changes occurring during the rehabilitation processes in patients after early stroke based on analysis of their upper limbs’ target-reaching movement and muscle co-activation. Ischemic stroke often results in reduced mobility of the upper extremities and frequently is a cause for long-term disability. The ever-developing technology of 3D movement analysis and miniaturisation of equipment for testing the bioelectrical activity of muscles can help to assess the progress of rehabilitation. The aim of this study was to examine the use of analysis of target-reaching movement indicators and muscle co-activation for diagnosing the rehabilitation process in post-…

Fluid Flow and Transfer ProcessesTechnologyQH301-705.5TPhysicsQC1-999Process Chemistry and TechnologyGeneral EngineeringEngineering (General). Civil engineering (General)rehabilitation; stroke; biomedical data; statistical analysisstrokerehabilitationComputer Science ApplicationsChemistrystatistical analysisGeneral Materials ScienceTA1-2040Biology (General)biomedical dataQD1-999InstrumentationApplied Sciences
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Stroke incidence, prevalence and mortality in women worldwide

2016

Background The study of sex differences on stroke incidence, prevalence and mortality is an emerging field of stroke epidemiology and care. Aims This study sought to determine the information available on stroke epidemiology in women worldwide and possible sex differences in stroke epidemiology, and, if so, describe the nature of these differences and whether they are consistent across countries/groups of countries. Summary We searched the available literature in English published between 1 January 2008 and 5 May 2015. Out of 17.789 papers only 56 peer-reviewed papers (29 community-based studies, 17 retrospective studies, 6 reviews, and 4 cross-sectional studies) have been included in the s…

GerontologyMalemedicine.medical_specialtyEpidemiologyEthnic Groups030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineSex FactorsFemalesEpidemiology; Females; Incidence; Mortality; Prevalence; Stroke; Age Factors; Ethnic Groups; Female; Humans; Male; Prevalence; Stroke; Survival Analysis; Sex Factors; NeurologyEpidemiologymedicineEthnicityPrevalenceHumansMortalityStrokebusiness.industryIncidence (epidemiology)IncidenceAge FactorsRetrospective cohort studymedicine.diseaseSurvival AnalysisStrokeEpidemiological transitionNeurologyFemalebusinessStroke incidence030217 neurology & neurosurgeryDemography
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Diabetes and Ischemic Stroke: An Old and New Relationship an Overview of the Close Interaction between These Diseases

2022

Diabetes mellitus is a comprehensive expression to identify a condition of chronic hyperglycemia whose causes derive from different metabolic disorders characterized by altered insulin secretion or faulty insulin effect on its targets or often both mechanisms. Diabetes and atherosclerosis are, from the point of view of cardio- and cerebrovascular risk, two complementary diseases. Beyond shared aspects such as inflammation and oxidative stress, there are multiple molecular mechanisms by which they feed off each other: chronic hyperglycemia and advanced glycosylation end-products (AGE) promote ‘accelerated atherosclerosis’ through the induction of endothelial damage and cellular dysfunction. …

Glycation End Products AdvancedOrganic ChemistryGeneral MedicineCatalysisComputer Science ApplicationsInorganic ChemistryHyperglycemiaHypertensionDiabetes MellitusAnimalsHumansAtherosclerosis Cerebrovascular disease Diabetes Stroke Animals Diabetes Mellitus Glycation End Products Advanced Humans Hyperglycemia Hypertension Ischemic StrokePhysical and Theoretical ChemistryMolecular BiologySpectroscopyIschemic Stroke
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Post-rehabilitation home exercises after stroke and hip fracture: results of a pilot study in Palermo

2010

Although most patients having sustained a stroke or hip fracture (PSHF) attend a period of therapy and rehabilitation program, it usually only last a few months and they may not continue an exercise program when the rehabilitation treatment has ended. Many Authors suggests that PSHF can improve or maintain the rehabilitation outcomes through an exercise program. At the geriatric assessment and integrated home-care Unit, Health-District 10, ASP6-Palermo, we enrolled 51 PSHF who were able to collaborate and follow the home exercise program and compared them with 50 PSHF who had been discharged from the same Unit in the period preceding the beginning of the study. The home exercise program was…

Home Exercise Stroke Hip Fracture
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Analgesic hypnotic treatment in a post-stroke patient

2021

In recent years, hypnotic suggestions have been used in several clinical conditions. This treatment is often used for anxiety treatment, somatization, and post-traumatic stress disorder. Hypnotic analgesia is one of the most clinically useful phenomena of hypnosis. The article describes the case of a patient who underwent hypnotic treatments for hypersensitivity and chronic pain. Results showed an improvement of pain control and a decrease of pain hypersensibility. In addition, during rehabilitative treatments, the patient reported a high level of compliance with the multidisciplinary team. These findings suggest that hypnosis could be a useful treatment for post-stroke pain management.

Hypnosismedicine.medical_specialtymedicine.drug_classmedicine.medical_treatmentAnalgesic050109 social psychologyHypnotic03 medical and health sciences0302 clinical medicinemedicineHumansHypnotics and Sedatives0501 psychology and cognitive sciencesPain MeasurementAnalgesicsRehabilitationbusiness.industry05 social sciencesChronic painGeneral Medicinemedicine.diseaseComplementary and alternative medicinePost strokePhysical therapyAnxietyAnalgesiamedicine.symptombusinessSomatizationHypnosis030217 neurology & neurosurgeryAmerican Journal of Clinical Hypnosis
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Acute Stroke Care during COVID-19: National Data.

2022

(1) Background: The pandemic of COVID-19 and subsequent lockdown strategies had a profound impact on many aspects of everyday life. During this time the world faced the unprecedented crisis of healthcare disrupting timely care delivery. This study was designed to evaluate the impact of the pandemic on the acute treatment of stroke in Poland. (2) Methods: The national data on hospitalizations with stroke as a primary diagnosis were obtained from the National Health Fund of Poland. Poisson regression was used to determine the significance of the change in hospital admissions. The differences between proportions were analyzed using the “N-1” Chi-squared test. (3) Results: During the COVID-19 p…

Infectious Diseasesacute stroke; COVID-19; pandemicInfectious disease reports
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