Search results for " Structure"

showing 10 items of 25475 documents

Tenascin in denervated human muscle

1996

Tenascin is a large oligomeric glycoprotein of the extracellular matrix. Its location is limited in innervated muscle tissues. We investigated immunohistologically, using two monoclonal antibodies (mab) against Tenascin, biopsied denervated human muscle of children and adults. Tenascin was present in the interstitial space among denervated muscle fibres. Accumulation of Tenascin in denervated adult muscle tissue was frequent, accumulation in denervated muscle tissue of children was sparse and weak. The two antibodies reacted correspondingly. Tenascin was not only found in the vicinity of atrophic muscle fibres, but also close to normally sized fibres, suggesting an early stage of denervatio…

chemistry.chemical_classificationMuscle tissueDenervationendocrine systemPathologymedicine.medical_specialtyanimal structuresbiologymedicine.drug_classTenascinmusculoskeletal systemMonoclonal antibodyExtracellular matrixmedicine.anatomical_structureNeurologychemistryInterstitial spaceembryonic structuresmedicinebiology.proteinImmunohistochemistryNeurology (clinical)GlycoproteinJournal of the Neurological Sciences
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Gender differences in implicit and explicit anxiety measures

2004

Abstract Explicit measures assess introspectively accessible self-descriptions and evaluations. In contrast, implicit measures assess introspectively inaccessible processes that operate outside of awareness. While women consistently yield higher scores on explicit anxiety measures, there are to date no studies available that examine gender differences in implicit anxiety measures. To analyse this topic, we used the Implicit Association Test (Study 1, N =248) and the Emotional Stroop task (Study 2, N =121) as implicit anxiety measures and a standard trait questionnaire as explicit anxiety measure. As expected, women scored higher on the explicit anxiety test. Women also yielded higher anxiet…

genetic structuresPsychometricsImplicit-association testContrast (statistics)Developmental psychologymedicineTraitAnxiety testAnxietymedicine.symptomPersonality Assessment InventoryPsychologypsychological phenomena and processesGeneral PsychologyStroop effectPersonality and Individual Differences
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Atrophic Forms (Dry AMD)

2009

Atrophic form of “Dry AMD” is defined by areas of RPE atrophy, often resulting from regression of confluent soft drusen.

medicine.medical_specialtyRPE atrophymedicine.anatomical_structuregenetic structuresbusiness.industryOphthalmologyMacular atrophymedicinesense organsSoft drusenOuter nuclear layerbusinesseye diseases
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Genetic-based evaluation of management units for sustainable vendace (Coregonus albula) fisheries in a large lake system

2022

Abstract The goal of the processing industry, trade and consumers is to get eco-labelled freshwater fish products from sustainable fisheries into the market as soon as possible. The fourth largest natural lake system in Europe, the Saimaa lake system supports a fishery for vendace (Coregonus albula). Certification of the fishery requires an understanding of population structure to help determine the number and spatial extent of management units. In this study, we analysed the genetic diversity of local vendace populations in the Saimaa lake system and aimed to identify the conservation and management units of vendace. Within the Saimaa, the genetic divergence between local populations of ve…

FisheryGenetic divergenceGenetic diversityGeographybiologyGeographical distancePopulation structureFreshwater fishCoregonus albulaLake districtAquatic ScienceLife historybiology.organism_classificationFisheries Research
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FUNCIONES NEUROPSICOLÓGICAS EN LAS HABILIDADES DE INICIO A LA LECTOESCRITURA

2016

Abstract:Numerous studies have tried to identify the set of skills and knowledge that are the basis for the development of literacy as phonological awareness, orthographic awareness and RAN. Since learning of literacy has its onset between 3 and 6 years, which is the maximum period of brain plasticity, it is clear the need to relate certain brain functions with the early onset of the skills that are the basis of its learning. Thus, the main objective of this work is the detection of neuropsychological functions that allow proper development of all those skills. Participants were 119 students who have been assessed twice, when 4 and 5 years old. The instruments used were the BIL, the Rapid A…

Visual perceptionSpatial structureEarly literacymedia_common.quotation_subject05 social sciences050301 educationLiteracy03 medical and health sciences0302 clinical medicinePhonological awarenessSet (psychology)Psychology0503 educationRapid automatized namingNeurocognitive030217 neurology & neurosurgerymedia_commonCognitive psychology
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Crystal structure of bis(cyclohexylammonium) diphenyldioxalatostannate(IV)

2015

In the title salt, (CyNH3)2[Sn(Ph2)(C2O4)2] (Cy is cyclo­hexyl and Ph is phen­yl), the SnPh2 moiety is chelated by two oxalate anions, leading to a cis arrangement within the distorted octa­hedral coordination sphere of the SnIV atom.

crystal structureStereochemistryOxalic acidcyclo­hexyl­ammoniumorganotin(IV) compoundSalt (chemistry)Crystal structureMedicinal chemistryOxalateResearch CommunicationsCrystalchemistry.chemical_compoundMoietyGeneral Materials ScienceCoordination geometrychemistry.chemical_classificationCrystallographycis arrangementHydrogen bondoxalate ligandsGeneral ChemistryCondensed Matter PhysicschemistryQD901-999N—H...O hydrogen bondingN—H⋯O hydrogen bondingcyclohexylammoniumActa Crystallographica Section E: Crystallographic Communications
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Cecal trap: CT findings of isolated cecal necrosis

2016

Learning objectives Background Findings and procedure details Conclusion Personal information References

genetic structuresGastrointestinal tractIschaemia / InfarctioneducationAbdomenEmergencyCT cecal necrosisAcuteContrast agent-intravenousSettore MED/36 - Diagnostica Per Immagini E RadioterapiaCT
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Synthesis and molecular and electronic structures of a series of Mo3CoSe4 cluster complexes with three different metal electron populations.

2008

The synthesis, crystal structure, and magnetic properties of [Mo 3(CoCO)Se 4(dmpe) 3Cl 3] ( 1), [Mo 3(CoCl)Se 4(dmpe) 3Cl 3] ( 2), and [Mo 3(CoCl)Se 4(dmpe) 3Cl 3](TCNQ) ([ 2](TCNQ)) (dmpe = 1,2-bis(dimethylphosphanyl)ethane; TCNQ = 7,7,8,8-tetracyanoquinomethane) cubane-type complexes with 16, 15, and 14 metal electrons, respectively, are reported. These compounds complete the series of cobalt-containing Mo 3CoQ 4 (Q = S, Se) cubane-type complexes, which allows a complete analysis of the consequences of replacing the inner chalcogen and the metal electron count on the structural, magnetic, and electrochemical properties. The experimental evidence is theoretically supported and rationalized…

ChemistryHeteroatomElectronCrystal structureElectrochemistrylaw.inventionInorganic ChemistryMetalChalcogenCrystallographylawComputational chemistryvisual_artvisual_art.visual_art_mediumPhysical and Theoretical ChemistryElectron paramagnetic resonanceHOMO/LUMOInorganic chemistry
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Patients experiencing statin-induced myalgia exhibit a unique program of skeletal muscle gene expression following statin re-challenge

2017

Statins, the 3-hydroxy-3-methyl-glutaryl (HMG)-CoA reductase inhibitors, are widely prescribed for treatment of hypercholesterolemia. Although statins are generally well tolerated, up to ten percent of statin-treated patients experience myalgia symptoms, defined as muscle pain without elevated creatinine phosphokinase (CPK) levels. Myalgia is the most frequent reason for discontinuation of statin therapy. The mechanisms underlying statin myalgia are not clearly understood. To elucidate changes in gene expression associated with statin myalgia, we compared profiles of gene expression in skeletal muscle biopsies from patients with statin myalgia who were undergoing statin re-challenge (cases)…

Male0301 basic medicinemyalgiaGene Expressionlcsh:MedicineApoptosis030204 cardiovascular system & hematologyPathology and Laboratory MedicineBioinformaticsBiochemistry0302 clinical medicineMedicine and Health SciencesGene Regulatory Networkslcsh:ScienceMusculoskeletal SystemEnergy-Producing OrganellesMyositisRegulation of gene expressionMultidisciplinaryCell DeathbiologyMusclesDrugsMiddle AgedMitochondriaCell ProcessesHMG-CoA reductaseFemalelipids (amino acids peptides and proteins)AnatomyCellular Structures and Organellesmedicine.symptomResearch ArticleSenescencemedicine.medical_specialtyStatinmedicine.drug_classPainBioenergeticsPolymorphism Single Nucleotide03 medical and health sciencesSigns and SymptomsDiagnostic MedicineInternal medicineGeneticsmedicineHumansGene Regulationcardiovascular diseasesMuscle SkeletalAgedPharmacologybusiness.industrylcsh:RStatinsBiology and Life SciencesComputational Biologynutritional and metabolic diseasesMyalgiaCell Biologymedicine.disease030104 developmental biologyEndocrinologyGene Expression RegulationSkeletal MusclesLeukocytes Mononuclearbiology.proteinProtein prenylationlcsh:QHydroxymethylglutaryl-CoA Reductase InhibitorsSLCO1B1businessPLOS ONE
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Evidence for the mechanosensor function of filamin in tissue development

2016

AbstractCells integrate mechanical properties of their surroundings to form multicellular, three-dimensional tissues of appropriate size and spatial organisation. Actin cytoskeleton-linked proteins such as talin, vinculin and filamin function as mechanosensors in cells, but it has yet to be tested whether the mechanosensitivity is important for their function in intact tissues. Here we tested, how filamin mechanosensing contributes to oogenesis in Drosophila. Mutations that require more or less force to open the mechanosensor region demonstrate that filamin mechanosensitivity is important for the maturation of actin-rich ring canals that are essential for Drosophila egg development. The ope…

MaleTalin0301 basic medicineanimal structuresFilaminsMutantmacromolecular substancesPlasma protein bindingFilaminmedicine.disease_causeArticle03 medical and health sciencesFilamin bindingOogenesismedicineAnimalsActinOvumMutationMultidisciplinarybiologyta1182VinculinActinsVinculin3. Good healthCell biology030104 developmental biologymechanosensor functionMutationddc:000biology.proteinDrosophilaFemaletissue developmentFunction (biology)Protein BindingScientific Reports
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