Search results for " Structures"
showing 10 items of 4162 documents
Repetitiveness Measures based on String Attractors and Burrows-Wheeler Transform: Properties and Applications
2023
Long Non Coding RNA H19: A New Player in Hypoxia-Induced Multiple Myeloma Cell Dissemination
2019
The long non-coding RNA H19 (lncH19) is broadly transcribed in the first stage of development and silenced in most cells of an adult organism
Efficient differentiation of embryonic stem cells into mesodermal precursors by BMP, retinoic acid and Notch signalling
2012
The ability to direct differentiation of mouse embryonic stem (ES) cells into specific lineages not only provides new insights into the pathways that regulate lineage selection but also has translational applications, for example in drug discovery. We set out to develop a method of differentiating ES cells into mesodermal cells at high efficiency without first having to induce embryoid body formation. ES cells were plated on a feeder layer of PA6 cells, which have membrane-associated stromal-derived inducing activity (SDIA), the molecular basis of which is currently unknown. Stimulation of ES/PA6 co-cultures with Bone Morphogenetic Protein 4 (BMP4) both favoured self-renewal of ES cells and…
Limited Resistance Rigid Perfectly Plastic Hinges for Steel Frames
2017
The paper concerns the proposal of a new special device for steel frames that can be utilized as external constraint as well as internal one connecting the structure beam elements. The device is designed as a rigid perfectly plastic hinge characterized by suitably chosen stiffness and resistance. Its constituting material is steel. The elastic stiffness and the limit resistance, treated as independent of each other, are fixed with the aim of satisfying special features required to the structure. The proposed device is thought as a sandwich section with wing thickness appropriately variable. Its dimensions are designed so that it can exhibit the fixed independent stiffness and limit resistan…
Influence of composition(CO2 and Sugar) on aroma release and perception of mint-flavored carbonated beverages
2009
The aim of the present work was to identify and quantify physical mechanisms responsible for in-nose aroma release during the consumption of mint-flavored carbonated beverages in order to better understand how they are perceived. The effect of two composition factors (sugar and CO(2)) was investigated on both the sensory and physicochemical properties of drinks by studying in vitro and in vivo aroma release. Sensory results revealed that the presence of CO(2) increased aroma perception regardless of the sugar content. In agreement with volatility parameters, in vivo measurements showed that carbonated drinks released a greater quantity of aroma compounds in the nose space than non-carbonate…
Classification of SD-OCT volumes with multi pyramids, LBP and HOG descriptors: application to DME detections.
2016
This paper deals with the automated detection of Diabetic Macular Edema (DME) on Optical Coherence Tomography (OCT) volumes. Our method considers a generic classification pipeline with preprocessing for noise removal and flattening of each B-Scan. Features such as Histogram of Oriented Gradients (HOG) and Local Binary Patterns (LBP) are extracted and combined to create a set of different feature vectors which are fed to a linear-Support Vector Machines (SVM) Classifier. Experimental results show a promising sensitivity/specificity of 0.75/0.87 on a challenging dataset.
Correlating Solution‐ and Solid‐State Structures of Conformationally Flexible Resorcinarenes: Significance of a Sulfonyl Group in Intramolecular Self…
2020
Abstract The synthesis of tetramethoxyresorcinarene podands bearing p‐toluene arms connected by ‐SO3‐ (1) and ‐CH2O‐ (2) linkers is presented herein. In the solid state, the resorcinarene podand 1 forms an intramolecular self‐inclusion complex with the pendant p‐toluene group of a podand arm, whereas the resorcinarene podand 2 does not show self‐inclusion. The conformations of the flexible resorcinarene podands in solution were investigated by variable‐temperature experiments using 1D and 2D NMR spectroscopic techniques as well as by computational methods, including a conformational search and subsequent DFT optimisation of representative structures. The 1H NMR spectra of 1 and 2 at room te…
Phase-bistable patterns and cavity solitons induced by spatially periodic injection into vertical-cavity surface-emitting lasers
2014
Spatial rocking is a kind of resonant forcing able to convert a self-oscillatory system into a phase-bistable, pattern forming system, whereby the phase of the spatially averaged oscillation field locks to one of two values differing by $\ensuremath{\pi}$. We propose the spatial rocking in an experimentally relevant system---the vertical-cavity surface-emitting laser (VCSEL)---and demonstrate its feasibility through analytical and numerical tools applied to a VCSEL model. We show phase bistability, spatial patterns, such as roll patterns, domain walls, and phase (dark-ring) solitons, which could be useful for optical information storage and processing purposes.
Resting-State Functional Magnetic Resonance Imaging for Brain Tumor Surgical Planning: Feasibility in Clinical Setting.
2019
The aim of this study was to introduce resting-state functional magnetic resonance imaging (rest-fMRI) capability for brain tumor surgical planning. rest-fMRI is an emerging functional neuroimaging technique potentially able to provide new insights into brain physiology and to provide useful information regarding brain tumors in preoperative and postoperative settings. rest-fMRI evaluates low-frequency fluctuations in the blood oxygen level–dependent signal while the subject is at rest during magnetic resonance imaging examination. Multiple resting-state networks have been identified, including the somatosensory, language, and visual networks, which are of primary importance for surgical pl…
Analysis of the Impact of the Triple Helix on Sustainable Innovation Targets in Spanish Technology Companies
2020
The establishment of broad-based networks, such as the Triple Helix, for innovation and sustainability is sufficiently corroborated. In this work we suggest that the information received from the Triple Helix has a significant and different impact on the objectives of sustainable innovation, depending on whether companies cooperate or not. To this end, an empirical analysis of a stratified sample of more than 5000 Spanish medium and high technology companies in 2010-2014-2015 was carried out. The results confirm that companies that do not cooperate place more importance on the information received from the Triple Helix to establish their sustainable innovation targets.