Search results for " TDCS"
showing 10 items of 23 documents
MEMORIA MOTORIA Protocollo di riabilitazione cognitiva dei disturbi del movimento, il ruolo della corteccia motoria primaria. Utilizzo di metodiche d…
l'obiettivo della presenti tesi è stato quello di verificare il ruolo della corteccia motoria primaria in un test cognitivo di memorizzazione e riconoscimento di immagini di movimento suddivisi in sequenza. Sono stati utilizzati strumenti di modulazione dell'attività cerebrale quali la TMS ( stimolazione magnetica transcranica) e per la registrazione dei MEP (potenziali evocati motori) e la tDCS (stimolazione cerebrale a corrente diretta) e per la modulazione dell'attività cerebrale durante lo svolgimento del compito cognitivo. Questi studi sono stati condotti grazie alla partecipazione di soggetti sani e soggetti con lesione cerebrale dell'emisfero desrtro. I risultati ottenuti sembrano di…
Transcranial direct current stimulation (TDCS) can modulate esophageal motility in gatroesophageal reflux disease (GERD)patients.
2012
Clinical effects of different montages of Transcranial Direct Current Stimulation (tDCS) in patients with Parkinson’s Disease
2016
Background: Parkinson’s disease (PD) is characterized by motor deficits which may not completely respond to the dopaminergic therapy, thus posing a therapeutic challenge. Non-invasive brain stimulation techniques such as transcranial direct current stimulation (tDCS) have shown promising results as possible alternative of treatment in different neurological disorders including PD. The therapeutic effect of tDCS, which may increase (anodal currents) or decrease (cathodal currents) the cortical excitability level, likely relies on modulation of cortico-subcortical interactions and abnormal patterns of cortical activation. Objective: To investigate safety and therapeutic potential of different…
Functional connectivity modulation induced by transcranial direct current stimulation of the motor network: a Resting-State fMRI study
2016
Resting-state functional connectivity represents a novel fMRI approach that allows detection of temporal correlations in spontaneous BOLD signal oscillations while subjects rest quietly in the scanner. Functional connectivity (FC) can be defined as the synchrony of neural activity among spatially distant regions. Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique that is known to modulate cortical activity and FC among brain regions. This study is aimed at measuring the variation of functional connectivity between cortical brain regions after tDCS along time. The temporal concatenation group ICA showed that immediately after anodal stimulation the a…
SHORT-TERM SYNAPTIC PLASTICITY IN MIGRAINE MOTOR CORTEX: EVIDENCE BY PRECONDITIONING OF HIGH-FREQUENCY REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION (…
2011
Background: Brief 5Hz repetitive transcranial magnetic stimulation (rTMS) trains at 120% of the resting- motorthreshold (RMT) intensity determine in healthy subjects a potentiation of motor evoked potentials (MEPs), likely due to short-term presynaptic plasticity facilitation. We recently showed paradoxical intensity-dependent MEP changes to 5Hz rTMS in migraine with MEP facilitation at 110% and inhibition at 130% RMT. This provides evidence of both hyper-responsivity and self-limiting hyperexcitability capacity in migraine, likely due to earlier activation of inhibitory homeostatic plasticity mechanisms. To explore this, we applied in migraineurs cathodal transcranial Direct Current Stimul…
Prismatic Adaptation as a new tool for non-invasive brain modulation: evidence from different neurophysiological techniques.
Neuromodulation of chronic headaches: position statement from the European Headache Federation
2013
The medical treatment of patients with chronic primary headache syndromes (chronic migraine, chronic tension-type headache, chronic cluster headache, hemicrania continua) is challenging as serious side effects frequently complicate the course of medical treatment and some patients may be even medically intractable. When a definitive lack of responsiveness to conservative treatments is ascertained and medication overuse headache is excluded, neuromodulation options can be considered in selected cases.Here, the various invasive and non-invasive approaches, such as hypothalamic deep brain stimulation, occipital nerve stimulation, stimulation of sphenopalatine ganglion, cervical spinal cord sti…
Brain stimulation in migraine
2013
Migraine is a very prevalent disease with great individual disability and socioeconomic burden. Despite intensive research effort in recent years, the etiopathogenesis of the disease remains to be elucidated. Recently, much importance has been given to mechanisms underlying the cortical excitability that has been suggested to be dysfunctional in migraine. In recent years, noninvasive brain stimulation techniques based on magnetic fields (transcranial magnetic stimulation, TMS) and on direct electrical currents (transcranial direct current stimulation, tDCS) have been shown to be safe and effective tools to explore the issue of cortical excitability, activation, and plasticity in migraine. M…
Resting state FMRI: A tool to investigate functional connectivity modulation induced by transcranial direct current stimulation of the motor network
2016
Introduction: Resting-state functional connectivity (fcMRI) represents a novel fMRI approach that allows detection of temporal correlations in spontaneous BOLD signal oscillations while subjects rest quietly in the scanner. Under resting conditions the brain is engaged in spontaneous activity that causes a low frequencies (<0.1 Hz) BOLD signal fluctuations. Functional connectivity (FC) can be defined as the synchrony of neural activity among spatially distant regions. Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique that is known to modulate cortical activity and FC among brain regions, as measured by functional magnetic resonance imaging. This st…
FUNCTIONAL CONNECTIVITY MODULATION INDUCED BY TRANSCRANIAL DIRECT CURRENT STIMULATION OF THE MOTOR NETWORK
2015
Background: Brain functions arise from the orchestrated activation and cooperation of networks of regions whose specific relationship varies dynamically across functional states. Resting state functional Magnetic Resonance Imaging (RS-fMRI) analyses focuses on spontaneous low frequency fluctuations (< 0.1 Hz) in the BOLD signal and investigates synchronous activations between regions that are spatially distinct (functional connectivity, FC), occurring in the absence of a task or stimulus. Transcranial Direct Current Stimulation (tDCS) is a non-invasive brain stimulation technique that is known to modulate cortical activity and FC among brain regions, as measured by functional Magnetic Reson…