Search results for " TMS"
showing 10 items of 37 documents
Motor intracortical inhibition in PD: L-DOPA modulation of high-frequency rTMS effects
2007
Dopaminergic drugs and deep brain stimulation restore cortical inhibition in Parkinson disease (PD) patients. High-frequency rTMS was also found to increase cortical inhibition in PD but its therapeutic effect is still controversial. Here we hypothesize that, if dopaminergic drugs reverse to normal cortical excitability in M1, the effect of high-frequency (hf)-rTMS in PD patients could depend on whether they are in a medicated or unmedicated state. The present study aims to explore the lasting effects of sub-threshold hf rTMS trains over M1 on cortical inhibition in patients with "on" and without "off" L-DOPA treatment. Fourteen PD patients were examined twice while "on" and "off" medicatio…
Left but not right temporal involvement in opaque idiom comprehension: a repetitive transcranial magnetic stimulation study
2004
Abstract It has been suggested that figurative language, which includes idioms, is controlled by the right hemisphere. We tested the right hemisphere hypothesis by using repetitive transcranial magnetic stimulation (rTMS) to transiently disrupt the function of the frontal and temporal areas of the right versus left hemisphere in a group of normal participants involved in a task of opaque idiom versus literal sentence comprehension. Forty opaque, nonambiguous idioms were selected. Fifteen young healthy participants underwent rTMS in two sessions. The experiment was run in five blocks, corresponding to the four stimulated scalp positions (left frontal and temporal and right frontal and tempor…
MEMORIA MOTORIA Protocollo di riabilitazione cognitiva dei disturbi del movimento, il ruolo della corteccia motoria primaria. Utilizzo di metodiche d…
l'obiettivo della presenti tesi è stato quello di verificare il ruolo della corteccia motoria primaria in un test cognitivo di memorizzazione e riconoscimento di immagini di movimento suddivisi in sequenza. Sono stati utilizzati strumenti di modulazione dell'attività cerebrale quali la TMS ( stimolazione magnetica transcranica) e per la registrazione dei MEP (potenziali evocati motori) e la tDCS (stimolazione cerebrale a corrente diretta) e per la modulazione dell'attività cerebrale durante lo svolgimento del compito cognitivo. Questi studi sono stati condotti grazie alla partecipazione di soggetti sani e soggetti con lesione cerebrale dell'emisfero desrtro. I risultati ottenuti sembrano di…
Ruolo dei processitop-down e bottom-up in compiti di ricerca visiva: studi con r-TMS
2009
Evaluating the role of dorsolateral prefrontal cortex on recognition memory with rTMS: evidence from healthy subjects and neurological patients
2010
Converging evidence from functional imaging and lesion studies suggested that a distributed neural network comprising the hippocampal formation, medial and lateral parietal regions as well as the prefrontal cortex is involved in episodic memory. Some findings suggested that successful memory formation requires the coordinated modulation of neural activity among these different cortical areas. It appears particularly important to understand the functional interactions between these regions during memory processes. My talk will be focused on the prefrontal contribution to verbal and non-verbal recognition memory and to familiarity and recollection processes. New evidence will be provided and …
The role of the prefrontal cortex in familiarity and recollection processes during verbal and non verbal recognition memory: a rTMS study
Neuroimaging and lesion studies have documented the involvement of the frontal lobes in recognition memory. However, the precise nature of prefrontal contributions to verbal and non verbal memory and to familiarity and recollection processes remains unclear. The aim of the current rTMS study was to investigate for the first time the role of the DLPFC in encoding and retrieval of non verbal and verbal memoranda and its contribution to recollection and familiarity processes. Recollection and familiarity processes were studied using the ROC and unequal variance signal detection methodologies. We found that rTMS delivered over left and right DLPFC at encoding resulted in material specific later…
Interazione tra diversi codici attenzionali: spazio e semantica
2010
The asymmetric distribution of human spatial attention has been repeatedly documented in both patients and healthy controls. Biases in the distribution of attention and/or in the mental representation of space may also affect some aspects of language processing. The present talk will be focused whether biases in attention and/or mental representation of space affect semantic representations. In particular, we investigated whether semantic judgments could be modulated by the location in space where the semantic information was presented and the role of the left and right parietal cortices in this task. Findings suggest the existence of an attentional and/or mental representational bias in se…