Search results for " Technik"
showing 9 items of 39 documents
Die totale Produktion: Technik, Kapital und die Logik der Unendlichkeit
2020
Im Begriff der totalen Produktion verdichtet sich Gérard Granels kritische Auseinandersetzung mit der metaphysischen Tradition zu einer Epochendiagnose für die industrialisierte Moderne. In einer ungewöhnlichen Zusammenführung der zentralen Denkbewegungen von Heidegger und Marx werden Technik und Kapital als Schlüsselakteure einer alles ergreifenden Logik der Unendlichkeit aufgewiesen, die seit den epistemologisch-technologischen Revolutionen der frühen Neuzeit nach und nach die geschichtliche Gestalt des Zeitalters bestimmt. Die entsprechende Grunderfahrung der modernen Welt, die Granel in ihrer ganzen ontologischen Vielschichtigkeit über ihre engere ökonomisch-industrielle Bedeutung hinau…
Radiation Hardness Assurance Through System-Level Testing: Risk Acceptance, Facility Requirements, Test Methodology, and Data Exploitation
2021
International audience; Functional verification schemes at a level different from component-level testing are emerging as a cost-effective tool for those space systems for which the risk associated with a lower level of assurance can be accepted. Despite the promising potential, system-level radiation testing can be applied to the functional verification of systems under restricted intrinsic boundaries. Most of them are related to the use of hadrons as opposed to heavy ions. Hadrons are preferred for the irradiation of any bulky system, in general, because of their deeper penetration capabilities. General guidelines about the test preparation and procedure for a high-level radiation test ar…
Öffnung für alle
2017
The printing press played a major role in the emergence of an open science system. The Mertonian scientific norms reflect this openness. They also demonstrate, however, that science understands itself as a profession of certified experts. The openness of science was enabled by social closure. Open science challenges this social closure of scientific practice. Der Buchdruck ermöglichte die Ausdifferenzierung eines modernen Wissenschaftssystems, das in kognitiver Hinsicht auf Offenheit orientiert ist. Die Mertonschen Normen können als Selbstreflexion dieser Orientierung an Offenheit interpretiert werden. An ihnen wird sichtbar, dass sich die zeitliche und sachliche Offenheit der Wissenschaft …
Validity, reliability, and responsiveness of daily monitoring visual analog scales in MASK-air®
2021
International audience; Background: MASK-air® is an app that supports allergic rhinitis patients in disease control. Users register daily allergy symptoms and their impact on activities using visual analog scales (VASs). We aimed to assess the concurrent validity, reliability, and responsiveness of these daily VASs. Methods: Daily monitoring VAS data were assessed in MASK-air® users with allergic rhinitis. Concurrent validity was assessed by correlating daily VAS values with those of the EuroQol-5 Dimensions (EQ-5D) VAS, the Control of Allergic Rhinitis and Asthma Test (CARAT) score, and the Work Productivity and Activity Impairment Allergic Specific (WPAI-AS) Questionnaire (work and activi…
The international EAACI/GA²LEN/EuroGuiDerm/APAAACI guideline for the definition, classification, diagnosis, and management of urticaria
2022
This update and revision of the international guideline for urticaria was developed following the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is a joint initiative of the Dermatology Section of the European Academy of Allergology and Clinical Immunology (EAACI), the Global Allergy and Asthma European Network (GALEN) and its Urticaria and Angioedema Centers of Reference and Excellence (UCAREs and ACAREs), the European Dermatology Forum (EDF; EuroGuiDerm), and the Asia Pacific Association of Allergy, Asthma and Clinical Immunology with the participation of 64 delegates of 50 national and international soci…
Sustained safety and efficacy of ligelizumab in patients with chronic spontaneous urticaria: A one‐year extension study
2021
Background: Ligelizumab, a next-generation, humanized anti-immunoglobulin E (IgE) monoclonal antibody is in development as a treatment for patients with chronic spontaneous urticaria, whose symptoms are inadequately controlled with standard-of-care therapy. Objective: To evaluate the long-term safety and re-treatment efficacy of ligelizumab 240 mg in patients who completed the core study and extension study. Methods: This open-label, single-arm, long-term Phase 2b extension study was designed to assess patients who were previously administered various doses of ligelizumab, omalizumab or placebo in the Phase 2b, dose-finding core study and who presented with active disease after Week 32. In …
Metodologiczne aspekty badań regionu śląskiego w okresie międzywojennym z socjologicznej perspektywy
2021
The paper demonstrates the methodologic aspect of the Polish sociologic research on the Silesian region in the interwar period. Referring to pre-sociologic and sociologic research, it depicts the methodologic foundations and intellectual perspectives that were conceptualised by ludwik krzy-wicki and constitute the cognitive basis for the construction of the knowledge about Silesia – they are defined as the object analysis current and the subject analysis current. The article illustrates the evolution of research methods – from the questionnaire technique, via the existing materials analy-sis, to Florian Znaniecki’s id method and the monographic method used in field research. it touches upon…
Equal access to the top? Measuring selection into finnish academia
2019
In this article, we draw a parallel between equality of opportunity in educational transitions and equality of opportunity in academic careers. In both cases, many methodological problems can be ameliorated by the use of longitudinal rather than cross-sectional data. We illustrate this point by using Finnish full-population register data to follow the educational and academic careers of the 1964–1966 birth cohorts from birth to the present day. We show how the Finnish professoriate is highly selected both in terms of parental background and in terms of gender. Individuals of different backgrounds differ greatly in the likelihood of completing different educational and academic transitions, …
Internalization of novel non-viral vector TAT-streptavidin into human cells
2007
BMC Biotechnology, 7 (1)