Search results for " Tom"

showing 10 items of 1742 documents

Whole-body MRI radiomics model to predict relapsed/refractory Hodgkin Lymphoma: A preliminary study.

2022

Purpose A strong prognostic score that enables a stratification of newly diagnosed Hodgkin Lymphoma (HL) to identify patients at high risk of refractory/relapsed disease is still needed. Our aim was to investigate the potential value of a radiomics analysis pipeline from whole-body MRI (WB-MRI) exams for clinical outcome prediction in patients with Hodgkin Lymphoma (HL). Materials and methods Index lesions from baseline WB-MRIs of 40 patients (22 females; mean age 31.7 ± 11.4 years) with newly diagnosed HL treated by ABVD chemotherapy regimen were manually segmented on T1-weighted, STIR, and DWI images for texture analysis feature extraction. A machine learning approach based on the Extra T…

AdultPositron emission tomographymedicine.medical_specialtyWhole body mriBiomedical EngineeringBiophysicsVinblastineBleomycinYoung AdultRefractoryRadiomicsPositron Emission Tomography Computed TomographyMachine learningAntineoplastic Combined Chemotherapy ProtocolsMedicineHumansRadiology Nuclear Medicine and imagingMagnetic resonance imaging Positron emission tomography Machine learning Texture analysis Hodgkin Lymphomamedicine.diagnostic_testHodgkin Lymphomabusiness.industryMagnetic resonance imagingMetabolic tumor volumeHodgkin DiseaseMagnetic Resonance ImagingDacarbazineTexture analysisPositron emission tomographyDoxorubicinRelapsed refractoryHodgkin lymphomaFemaleRadiologySettore MED/36 - Diagnostica Per Immagini E RadioterapiabusinessMagnetic resonance imaging
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Differential Effects of Exercise on Tibial Shaft Marrow Density in Young Female Athletes

2013

Increased mechanical loading can promote the preferential differentiation of bone marrow mesenchymal stem cells to osteoblastogenesis, but it is not known whether long-term bone strength-enhancing exercise in humans can reduce marrow adiposity.Our objective was to examine whether bone marrow density (MaD), as an estimate of marrow adiposity 1) differs between young female athletes with contrasting loading histories and bone strengths and 2) is an independent predictor of bone strength at the weight-bearing tibia.Mid-tibial MaD, cortical area (CoA), total area, medullary area, strength strain index (SSI), and cortical volumetric bone mineral density (vBMD) (total, endocortical, midcortical, …

Adultmedicine.medical_specialtyAdolescentChemical PhenomenaMedullary cavityEndocrinology Diabetes and MetabolismAdipocytes WhiteClinical BiochemistryBone Marrow CellsContext (language use)BiochemistryWeight-BearingYoung AdultEndocrinologyBone DensityBone MarrowOsteogenesisInternal medicinemedicineHumansTibiaQuantitative computed tomographyExerciseAdiposityBone mineralOsteoblastsTibiabiologymedicine.diagnostic_testAthletesbusiness.industryBiochemistry (medical)Adolescent Developmentbiology.organism_classificationPeripheralEndocrinologymedicine.anatomical_structureAthletesFemaleDiaphysesBone marrowTomography X-Ray ComputedbusinessThe Journal of Clinical Endocrinology & Metabolism
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Bone age determination based on the study of the medial extremity of the clavicle

1998

The development of the medial clavicular epiphysis and its fusion with the clavicular shaft have been a subject of medical research since the second decade of this century. Computed tomography provides the imaging modality of choice in analyzing the maturation process of the sternal end of the clavicle. In a retrospective study, we analyzed normal development in 380 individuals under the age of 30 years. The appearance of an epiphyseal ossification center occurred between ages 11 and 22 years. Partial union was found from age 16 until age 26 years. Complete union was first noted at age 22 years and in 100 % of the sample at age 27 years. Based on these data, age-related standardized age dis…

Adultmedicine.medical_specialtyAdolescentComputed tomographyOssification centerReference ValuesAge Determination by SkeletonmedicineHumansRadiology Nuclear Medicine and imagingChildRetrospective StudiesNeuroradiologyOrthodonticsmedicine.diagnostic_testOssificationbusiness.industryInfantRetrospective cohort studyBone ageGeneral MedicineClavicleSurgerymedicine.anatomical_structureClavicleEpiphysisChild PreschoolRadiologymedicine.symptomTomography X-Ray ComputedbusinessEpiphysesEuropean Radiology
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Bone’s Structural Diversity in Adult Females Is Established before Puberty

2009

Bone must be rigid for leverage yet light for mobility. We studied how bone modeling and remodeling fashioned differences in bone size, shape, and mass during growth to achieve these properties in adulthood.We measured the structural features of a tibial cross-section using quantitative computed tomography and markers of remodeling in 258 10- to 13-yr-old girls during 2 yr and in 108 of their mothers.Tibia total cross-sectional area and mass correlated between daughters and their mothers (r = 0.34 and 0.44, respectively, both P0.01). The location of a daughter's tibial total cross-sectional area, medullar area, and bone mass in the lower, middle, or upper part of the sample distribution was…

Adultmedicine.medical_specialtyAdolescentEndocrinology Diabetes and Metabolismmedia_common.quotation_subjectClinical BiochemistryStructural diversityBiologyBiochemistryBone and BonesBone modelingFractures BoneEndocrinologyBone DensityInternal medicinemedicineHumansTibiaQuantitative computed tomographyChildmedia_commonBone mineralDaughterBone DevelopmentAnthropometryTibiamedicine.diagnostic_testPubertyBiochemistry (medical)Nutritional statusMiddle AgedEndocrinologyFemaleBone RemodelingBone massThe Journal of Clinical Endocrinology & Metabolism
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Lens-vault analysis and its correlation with other biometric parameters using swept-source OCT

2021

Purpose To measure lens vault (LV) and to assess its correlation with various ocular parameters in healthy eyes, using for all measurements the same high-resolution swept-source optical coherence tomographer (SS-OCT). Methods We prospectively recruited 67 Caucasian healthy patients whose mean age was 41.9 ± 12.4 years; only their right eye was included in the study. Data were all recorded with the ANTERION SS-OCT and comprised, for each patient, 5 consecutive measurements of LV, anterior chamber depth (ACD), lens thickness (LT), axial length (AL), white-to-white (WTW) distance, central corneal thickness (CCT), anterior chamber volume (ACV) and spur-to-spur (STS) distance. Results Mean LV wa…

Adultmedicine.medical_specialtyBiometryAnterior ChamberSignificant negative correlationPositive correlationSwept-source Fourier domainCorrelationLens thicknessOphthalmologyLens CrystallineHumansMedicineOptical coherence tomographybusiness.industrySpur-to-spurReproducibility of ResultsMean ageAxial lengthWhite-to-whiteMiddle AgedClinical routineCrystalline lens riseAxial Length Eyemedicine.anatomical_structureLens (anatomy)Original ArticlebusinessTomography Optical CoherenceOptometryJournal of Optometry
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Bone metastasis of a breast cancer detected by 3'-deoxy-3'-18F-fluorothymidine PET/CT

2008

International audience

Adultmedicine.medical_specialtyBone NeoplasmsBreast NeoplasmsDocetaxel[SDV.IB.MN]Life Sciences [q-bio]/Bioengineering/Nuclear medicine030204 cardiovascular system & hematology01 natural sciencesBone and Bones[SDV.IB.MN] Life Sciences [q-bio]/Bioengineering/Nuclear medicine[ SDV.IB.MN ] Life Sciences [q-bio]/Bioengineering/Nuclear medicine03 medical and health sciences0302 clinical medicineBreast cancermedicineHumansRadiology Nuclear Medicine and imagingComputingMilieux_MISCELLANEOUSEpirubicinPET-CT010405 organic chemistrybusiness.industryBone metastasisGeneral Medicinemedicine.diseaseDideoxynucleosides3. Good health0104 chemical sciences18f fluorothymidineTreatment OutcomePositron-Emission TomographyFemaleTaxoidsRadiologybusinessTomography X-Ray Computed
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SPECT Bone scintigraphy of benign and malignant lesions of the spine

1989

70 patients were examined with planar and SPECT bone scintigraphy. SPECT proved to be superior over planar bone scanning for imaging of traumatic, inflammatory, and malignant bone lesions. SPECT provides three-dimensional information and, therefore, delineates the exact location and extension of lesions. It also has a higher sensitivity than planar bone scintigraphy. The three-dimensional bone scan generates complementary diagnostic information which often facilitates an adequate therapy protocol.

Adultmedicine.medical_specialtyDiagnostic informationHumansMedicineRachisTomography Emission-Computed Single-PhotonSpinal Neoplasmsmedicine.diagnostic_testbusiness.industryGeneral MedicineSpineVertebraBone scanningmedicine.anatomical_structureBone scintigraphyBone lesionPositron emission tomographyFemaleSpinal DiseasesSurgeryNeurology (clinical)NeurosurgeryRadiologybusinessNuclear medicineNeurosurgical Review
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Virtopsy and Living Individuals Evaluation Using Computed Tomography in Forensic Diagnostic Imaging

2019

The applications of forensic radiology involve both Virtopsy both studies on living people - to demonstrate bone age, search for foreign bodies, such as voluntary injection of drug ovules or surgical sponges accidentally forgotten, to assess gunshot wounds, to evaluate injuries by road accidents, and cases of violence or abuse (both in adults and in children). Computed tomography is the most used imaging tool used in forensic pathology and its indications are mainly focused on cases of unnatural deaths or when a crime is suspected. It is preferred over the standard autopsy in selected cases, such as in putrefied, carbonized or badly damaged bodies; or as a preliminary evaluation in mass dis…

Adultmedicine.medical_specialtyForensic pathologyAutopsyComputed tomographyWounds Nonpenetrating030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineVirtopsyAge Determination by SkeletonMedical imagingHumansMedicineRadiology Nuclear Medicine and imagingChildmedicine.diagnostic_testbusiness.industryGeneral surgerySurgical SpongesForensic MedicineForeign BodiesForensic scienceForensic radiologyWounds GunshotAutopsyTomography X-Ray Computedbusiness030217 neurology & neurosurgerySeminars in Ultrasound, CT and MRI
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Neuromuscular performance and body mass as indices of bone loading in premenopausal and postmenopausal women.

2009

The strong association between body mass and skeletal robusticity has been attributed to increasing skeletal loading with increasing mass. However, it is unclear whether body mass is merely a coarse substitute for bone loading rather than a true independent predictor of bone strength. As indices of neuromuscular performance, impulse and peak power were determined from vertical ground reaction force during a maximal counter movement jump test in 221 premenopausal and 82 postmenopausal women. Bone compressive (BSI(d) g(2)/cm(4)) and bending (SSImax(mid) mm(3)) strength indices were measured with peripheral quantitative computed tomography (pQCT) at the distal ((d)) and midshaft ((mid)) sites …

Adultmedicine.medical_specialtyHistologyCompressive StrengthPhysiologyEndocrinology Diabetes and MetabolismMovementPhysical Exertion030209 endocrinology & metabolismIndependent predictorWeight-Bearing03 medical and health sciences0302 clinical medicineBone strengthBone loadingWeight lossOsteoarthritisMedicineHumansTibiaMuscle StrengthQuantitative computed tomography030304 developmental biologyOrthodontics0303 health sciencesHip fracturePostmenopausal womenmedicine.diagnostic_testTibiabusiness.industryBody WeightAge FactorsMiddle Agedmedicine.diseaseSurgeryPostmenopauseRadiographyPremenopauseBody CompositionRegression AnalysisFemaleStress Mechanicalmedicine.symptombusinessMuscle ContractionBone
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The diagnostic value of CT for radiotherapy of cerebral tumors

1978

The paper deals with CT followup studies on 73 patients with cerebral tumors who received radiotherapy. The value of CT for the indication of radiotherapy, for followup therapy and for the demonstration of therapeutic success are discussed. Since the cerebral tumors become visualized by means of CT in their entire extent and can be differentiated from perifocal edema, the question arises whether radiotherapy should consist of higher doses in the future. It is also suggested that the "clinical malignancy" may be used to compare the behavior of cerebral tumors when there is no exact histological classification. The possible histopathological effects of radiotherapy (edema, necrosis) and their…

Adultmedicine.medical_specialtyNeurologymedicine.medical_treatmentBreast NeoplasmsComputed tomographyMalignancyEdemaHumansMedicinePerifocal edemaRadiology Nuclear Medicine and imagingNeoplasm MetastasisChildNeuroradiologymedicine.diagnostic_testBrain Neoplasmsbusiness.industryMiddle Agedmedicine.diseaseRadiation therapyFemaleNeurology (clinical)RadiologyNeurosurgerymedicine.symptomTomography X-Ray ComputedCardiology and Cardiovascular MedicinebusinessPinealomaFollow-Up StudiesNeuroradiology
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